CN101549148A - 多肽在制备用于促进心内膜细胞向间质细胞转化的药物中的应用 - Google Patents
多肽在制备用于促进心内膜细胞向间质细胞转化的药物中的应用 Download PDFInfo
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- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/26—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against hormones ; against hormone releasing or inhibiting factors
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
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| CNA028166884A Pending CN1547480A (zh) | 2001-08-29 | 2002-08-29 | 用胸腺素β4、类似物、同型物和其他衍生物在心肌事件发生前、过程中或刚发生后治疗或预防炎症、损伤和其他改变的方法 |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN109789182A (zh) * | 2016-07-18 | 2019-05-21 | 雷根特里有限责任公司 | 治疗干眼综合征的方法 |
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| EP2266595A3 (en) * | 2002-02-06 | 2011-07-06 | Regenerx Biopharmaceuticals, Inc. | Treatment of infections and other disorders |
| WO2006076254A2 (en) * | 2005-01-11 | 2006-07-20 | Regenerx Biopharmaceuticals, Inc. | Method of treating or preventing respiratory microbial infection of respiratory tissue |
| US20080051348A1 (en) * | 2002-02-06 | 2008-02-28 | Regenerx Biopharmaceuticals, Inc. | Treatment of infections and other disorders |
| CN1852727A (zh) * | 2003-03-31 | 2006-10-25 | 雷金纳克斯生物制药公司 | 递送胸腺素β4、类似物、同工型和其它衍生物的组合物和方法 |
| CA2532542A1 (en) * | 2003-07-18 | 2005-01-27 | Regenerx Biopharmaceuticals, Inc. | Treatment or prevention of damage due to radiation exposure |
| US20090053194A1 (en) * | 2003-12-22 | 2009-02-26 | Regenerx Biopharmaceuticals, Inc. | Method of treating or preventing biological or immunological responses to a reactive chemical or biological or toxic agent |
| WO2005087805A1 (en) * | 2004-03-05 | 2005-09-22 | Regenerx Biopharmaceuticals, Inc. | Treating or preventing extracellular matrix build-up |
| JP2008510732A (ja) * | 2004-08-20 | 2008-04-10 | ザ・ボード・オブ・リージェンツ・オブ・ザ・ユニバーシティ・オブ・テキサス・システム | 心臓組織の損傷を処置、予防、阻害、または緩和する方法 |
| US7531318B2 (en) | 2004-08-20 | 2009-05-12 | Board Of Regents, The University Of Texas System | Screening of agents for activity against ischemic myocardial insults |
| CA2612522A1 (en) * | 2005-06-17 | 2006-12-28 | Regenerx Biopharmaceuticals, Inc. | Lkktet and/or lkktnt peptide compositions and methods |
| JP2009502938A (ja) * | 2005-07-26 | 2009-01-29 | リジェナークス・バイオファーマスーティカルズ・インコーポレイテッド | 鬱血性心不全が原因である組織の劣化、損傷、または破損を処置または予防する方法 |
| WO2007014254A2 (en) * | 2005-07-26 | 2007-02-01 | Regenerx Biopharmaceuticals, Inc. | Method of treating or preventing tissue deterioration, injury or damage due to hypertrophic muscle disease |
| CN100372572C (zh) * | 2005-09-29 | 2008-03-05 | 北京诺思兰德生物技术有限责任公司 | 携带人胸腺素β4基因的重组质粒 |
| US8399412B2 (en) * | 2006-10-06 | 2013-03-19 | Regenerx Biopharmaceuticals, Inc. | Method of treating or preventing tissue deterioration, injury or damage due to periodontal disease or disease of oral mucosa, and/or downregulating NF-kappabeta or supressing NF-kappabeta-mediated actions |
| HUP0600814A3 (en) * | 2006-10-27 | 2009-08-28 | Biostatin Gyogyszerkutato Fejl | Peptides for activation of angiogenesis, pharmaceutical compounds containing same and use of these compounds |
| MX2010010177A (es) * | 2008-03-17 | 2012-08-23 | Regenerx Biopharmaceuticals | Fragmentos de beta timosina mejorada. |
| KR101297037B1 (ko) * | 2010-03-26 | 2013-08-14 | 숙명여자대학교산학협력단 | 혈관신생촉진용 펩타이드 및 이의 용도 |
| BR112013000923A2 (pt) * | 2010-07-14 | 2016-05-17 | Adistem Ltd | método de tratamento de hiv ou aids |
| WO2012044783A2 (en) * | 2010-09-30 | 2012-04-05 | Regenerx Biopharmaceuticals, Inc. | Method of achieving a thymosin beta 4 concentration in a human patient |
| WO2021225960A2 (en) * | 2020-05-05 | 2021-11-11 | Regenerx Biopharmaceuticals, Inc. | Beta thymosin peptides for treating viral infections |
| CN111821424B (zh) * | 2020-07-21 | 2023-03-31 | 广东海洋大学深圳研究院 | 胸腺素及其衍生物的应用和治疗抑郁症的药物 |
| CN112023027B (zh) * | 2020-07-21 | 2023-03-14 | 广东海洋大学 | 胸腺素或其衍生物的应用和治疗快感缺乏型抑郁症的药物 |
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| US4297276A (en) * | 1979-03-23 | 1981-10-27 | Hoffman-La Roche Inc. | Thymosin beta 3 and beta 4 |
| JPS61500431A (ja) | 1982-12-09 | 1986-03-13 | ビルトン，ジエラルド エル． | 傷治癒に有用な活性化され、安定化された酵素 |
| US4543340A (en) | 1983-04-07 | 1985-09-24 | George Washington University | Radioimmunoassay of thymosin β4 |
| JPH02124815A (ja) | 1987-10-29 | 1990-05-14 | Takeda Chem Ind Ltd | 血管形成促進剤 |
| US5654267A (en) | 1988-12-20 | 1997-08-05 | La Jolla Cancer Research Center | Cooperative combinations of ligands contained within a matrix |
| JPH03178988A (ja) | 1989-09-14 | 1991-08-02 | Takeda Chem Ind Ltd | 生理活性物質ｔａｎ―８８３、その製造法および用途 |
| CN1173991C (zh) | 1992-11-13 | 2004-11-03 | 马克斯普朗克科学促进协会 | 作为血管内皮生长因子受体的f1k-1 |
| EP0725652A1 (en) | 1993-10-07 | 1996-08-14 | The George Washington University Medical Center | METHOD OF TREATING SEPTIC SHOCK USING THYMOSIN $g(b) 4? |
| US5578570A (en) | 1993-10-07 | 1996-11-26 | The George Washington University Medical Center | Method of treating septic shock using thymosin β4 |
| AU3733295A (en) | 1994-10-06 | 1996-05-02 | Alpha 1 Biomedicals, Inc. | Treatment of obstructive airway disease by administering thymosin beta 4, or coadministration of thymosin beta 4 and dnase i |
| US5663071A (en) | 1996-06-17 | 1997-09-02 | Children's Medical Center Corporation | Human thymosin β 15 gene, protein and uses thereof |
| US6013780A (en) * | 1996-09-06 | 2000-01-11 | Technion Research & Development Co. Ltd. | VEGF145 expression vectors |
| GB9806632D0 (en) | 1998-03-28 | 1998-05-27 | Stevenson Robert | Peptide factor |
| JP4301602B2 (ja) | 1998-09-28 | 2009-07-22 | 株式会社マルハニチロ水産 | 血管内皮細胞増殖促進剤 |
| PT1100529E (pt) | 1998-07-30 | 2005-10-31 | Us Gov Health & Human Serv | A timosina beta 4 promove a preparacao de feridas |
| US7560280B2 (en) * | 2000-11-03 | 2009-07-14 | Kourion Therapeutics Gmbh | Human cord blood derived unrestricted somatic stem cells (USSC) |
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- 2002-08-29 US US10/488,084 patent/US9056087B2/en not_active Expired - Lifetime
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109789182A (zh) * | 2016-07-18 | 2019-05-21 | 雷根特里有限责任公司 | 治疗干眼综合征的方法 |
Also Published As
| Publication number | Publication date |
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| CA2458883A1 (en) | 2003-03-13 |
| EP1427432A4 (en) | 2008-01-23 |
| US9056087B2 (en) | 2015-06-16 |
| CA2458883C (en) | 2017-11-28 |
| JP2009221211A (ja) | 2009-10-01 |
| WO2003020215A2 (en) | 2003-03-13 |
| JP2005502672A (ja) | 2005-01-27 |
| WO2003020215A3 (en) | 2004-03-25 |
| CN1547480A (zh) | 2004-11-17 |
| AU2002336408B2 (en) | 2006-12-21 |
| EP1427432A2 (en) | 2004-06-16 |
| MXPA04001942A (es) | 2004-07-23 |
| US20040258680A1 (en) | 2004-12-23 |
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