JP2005501548A5 - - Google Patents

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Publication number
JP2005501548A5
JP2005501548A5 JP2003525297A JP2003525297A JP2005501548A5 JP 2005501548 A5 JP2005501548 A5 JP 2005501548A5 JP 2003525297 A JP2003525297 A JP 2003525297A JP 2003525297 A JP2003525297 A JP 2003525297A JP 2005501548 A5 JP2005501548 A5 JP 2005501548A5
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JP
Japan
Prior art keywords
fusion protein
enzyme
protein
cell
cellular
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Application number
JP2003525297A
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English (en)
Japanese (ja)
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JP5580505B2 (ja
JP2005501548A (ja
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Priority claimed from PCT/US2002/027497 external-priority patent/WO2003021265A1/en
Publication of JP2005501548A publication Critical patent/JP2005501548A/ja
Publication of JP2005501548A5 publication Critical patent/JP2005501548A5/ja
Application granted granted Critical
Publication of JP5580505B2 publication Critical patent/JP5580505B2/ja
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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JP2003525297A 2001-08-30 2002-08-27 遺伝子構築細胞モニターシステム Expired - Lifetime JP5580505B2 (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US31642801P 2001-08-30 2001-08-30
US60/316,428 2001-08-30
US34315601P 2001-10-21 2001-10-21
US60/343,156 2001-10-22
US35308602P 2002-01-30 2002-01-30
US60/353,086 2002-01-30
PCT/US2002/027497 WO2003021265A1 (en) 2001-08-30 2002-08-27 Genetic construct intracellular monitoring system

Publications (3)

Publication Number Publication Date
JP2005501548A JP2005501548A (ja) 2005-01-20
JP2005501548A5 true JP2005501548A5 (https=) 2008-11-20
JP5580505B2 JP5580505B2 (ja) 2014-08-27

Family

ID=27405870

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2003525297A Expired - Lifetime JP5580505B2 (ja) 2001-08-30 2002-08-27 遺伝子構築細胞モニターシステム

Country Status (6)

Country Link
US (1) US7479377B2 (https=)
EP (1) EP1421385B1 (https=)
JP (1) JP5580505B2 (https=)
AU (1) AU2002332724A1 (https=)
CA (1) CA2458879C (https=)
WO (1) WO2003021265A1 (https=)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1582332A (zh) * 2001-12-29 2005-02-16 Seoul大学校产学协力财团 转染gfp的克隆猪、敲除gt的克隆猪及其生产方法
EP1556682B8 (en) * 2002-10-21 2010-02-17 DiscoveRx Corporation Ip3 protein binding assay
JP2007521021A (ja) * 2003-11-06 2007-08-02 ディスカヴァーエックス インコーポレイテッド 細胞膜タンパク質の検定
US8586294B2 (en) * 2004-05-18 2013-11-19 The Board Of Trustees Of The Leland Stanford Junior University Detection of protein translocation by beta-galactosidase reporter fragment complementation
JP4796059B2 (ja) 2004-06-30 2011-10-19 ディスカヴァーエックス コーポレイション 細胞内修飾の分析
WO2007002200A2 (en) * 2005-06-21 2007-01-04 Discoverx, Inc. Mitotic index assay
WO2009043953A1 (es) * 2007-10-05 2009-04-09 Proyecto De Biomedicina Cima, S.L. Empleo de inhibidores de ppar alfa truncado en el tratamiento de la insuficiencia cardiaca en sujetos con cardiopatía hipertensiva
US8865421B2 (en) * 2008-07-02 2014-10-21 Discoverx Corporation Assays for nuclear hormone receptor binding
US20100120063A1 (en) * 2008-10-10 2010-05-13 Discoverx Corporation GPCR Arrestin Assays
US8211655B2 (en) * 2009-02-12 2012-07-03 Discoverx Corporation Wild-type receptor assays
GB0905419D0 (en) 2009-03-30 2009-05-13 Ge Healthcare Uk Ltd Methods for testing ligand binding to G protein-coupled receptors
GB0917877D0 (en) 2009-10-13 2009-11-25 Ge Healthcare Uk Ltd Enzyme fragment complementation assays for monitoring the activiation of the voltage-gated potassium ion channel herg
WO2013119579A1 (en) * 2012-02-06 2013-08-15 Discoveryx Corporation Detection of intracellular binding events by measuring protein abundance

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5604091A (en) * 1984-03-01 1997-02-18 Microgenics Corporation Methods for protein binding enzyme complementation
US4708929A (en) * 1984-10-29 1987-11-24 Microgenics Corporation Methods for protein binding enzyme complementation assays
DE69731960T2 (de) * 1996-09-24 2005-12-15 Cadus Pharmaceutical Corp. Verfahren und zusammensetzungen für die identifizierung von receptor effectoren
US6037133A (en) * 1998-04-17 2000-03-14 Clontech Laboratories, Inc. IκBEGFP constructs, cell lines and methods of use

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