JP2005343897A5 - - Google Patents
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- Publication number
- JP2005343897A5 JP2005343897A5 JP2005161734A JP2005161734A JP2005343897A5 JP 2005343897 A5 JP2005343897 A5 JP 2005343897A5 JP 2005161734 A JP2005161734 A JP 2005161734A JP 2005161734 A JP2005161734 A JP 2005161734A JP 2005343897 A5 JP2005343897 A5 JP 2005343897A5
- Authority
- JP
- Japan
- Prior art keywords
- liquid formulation
- taxane
- formulation according
- agents
- liquid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000012669 liquid formulation Substances 0.000 claims 10
- 239000003795 chemical substances by application Substances 0.000 claims 7
- 229940123237 Taxane Drugs 0.000 claims 6
- DKPFODGZWDEEBT-QFIAKTPHSA-N taxane Chemical class C([C@]1(C)CCC[C@@H](C)[C@H]1C1)C[C@H]2[C@H](C)CC[C@@H]1C2(C)C DKPFODGZWDEEBT-QFIAKTPHSA-N 0.000 claims 6
- 239000008137 solubility enhancer Substances 0.000 claims 5
- 239000007972 injectable composition Substances 0.000 claims 4
- 239000003381 stabilizer Substances 0.000 claims 4
- 229940079593 drug Drugs 0.000 claims 3
- 239000003814 drug Substances 0.000 claims 3
- VLKZOEOYAKHREP-UHFFFAOYSA-N n-Hexane Chemical compound CCCCCC VLKZOEOYAKHREP-UHFFFAOYSA-N 0.000 claims 3
- GVJHHUAWPYXKBD-UHFFFAOYSA-N (±)-α-Tocopherol Chemical compound OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-UHFFFAOYSA-N 0.000 claims 2
- LYCAIKOWRPUZTN-UHFFFAOYSA-N Ethylene glycol Chemical compound OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 claims 2
- 229930012538 Paclitaxel Natural products 0.000 claims 2
- 238000000034 method Methods 0.000 claims 2
- 229960001592 paclitaxel Drugs 0.000 claims 2
- RCINICONZNJXQF-MZXODVADSA-N taxol Chemical compound O([C@@H]1[C@@]2(C[C@@H](C(C)=C(C2(C)C)[C@H](C([C@]2(C)[C@@H](O)C[C@H]3OC[C@]3([C@H]21)OC(C)=O)=O)OC(=O)C)OC(=O)[C@H](O)[C@@H](NC(=O)C=1C=CC=CC=1)C=1C=CC=CC=1)O)C(=O)C1=CC=CC=C1 RCINICONZNJXQF-MZXODVADSA-N 0.000 claims 2
- 208000019553 vascular disease Diseases 0.000 claims 2
- AOBORMOPSGHCAX-UHFFFAOYSA-N Tocophersolan Chemical compound OCCOC(=O)CCC(=O)OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C AOBORMOPSGHCAX-UHFFFAOYSA-N 0.000 claims 1
- 229930003427 Vitamin E Natural products 0.000 claims 1
- 201000010099 disease Diseases 0.000 claims 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 1
- WIGCFUFOHFEKBI-UHFFFAOYSA-N gamma-tocopherol Natural products CC(C)CCCC(C)CCCC(C)CCCC1CCC2C(C)C(O)C(C)C(C)C2O1 WIGCFUFOHFEKBI-UHFFFAOYSA-N 0.000 claims 1
- WGCNASOHLSPBMP-UHFFFAOYSA-N hydroxyacetaldehyde Natural products OCC=O WGCNASOHLSPBMP-UHFFFAOYSA-N 0.000 claims 1
- 239000000725 suspension Substances 0.000 claims 1
- 229940046009 vitamin E Drugs 0.000 claims 1
- 235000019165 vitamin E Nutrition 0.000 claims 1
- 239000011709 vitamin E Substances 0.000 claims 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10/858,954 US7989490B2 (en) | 2004-06-02 | 2004-06-02 | Injectable formulations of taxanes for cad treatment |
| US858954 | 2004-06-02 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2005343897A JP2005343897A (ja) | 2005-12-15 |
| JP2005343897A5 true JP2005343897A5 (enExample) | 2011-03-31 |
| JP5615474B2 JP5615474B2 (ja) | 2014-10-29 |
Family
ID=35124435
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2005161734A Expired - Fee Related JP5615474B2 (ja) | 2004-06-02 | 2005-06-01 | Ｃａｄ治療のためのタキサンの注入可能な配合物 |
Country Status (4)
| Country | Link |
|---|---|
| US (2) | US7989490B2 (enExample) |
| EP (1) | EP1618879B1 (enExample) |
| JP (1) | JP5615474B2 (enExample) |
| CA (1) | CA2509077C (enExample) |
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| KR20030019328A (ko) * | 2000-03-24 | 2003-03-06 | 아이박스 리서치 인코포레이티드 | 탁산-기저 조성물 및 이를 이용한 방법 |
| JP2004536026A (ja) | 2000-11-28 | 2004-12-02 | トランスフォーム ファーマシューティカルズ，インコーポレーティッド． | パクリタキセル、その誘導体、および薬剤として許容される塩を含む医薬品製剤 |
| DE10115740A1 (de) * | 2001-03-26 | 2002-10-02 | Ulrich Speck | Zubereitung für die Restenoseprophylaxe |
| CA2471572A1 (en) | 2001-12-28 | 2003-07-17 | Ivax Research, Inc. | Taxane based compositions and methods of use |
| ES2283756T3 (es) * | 2002-03-01 | 2007-11-01 | Novagali Pharma Sa | Sistemas autoemulsionantes de administracion de farmaco para taxoides. |
| ITMI20020680A1 (it) * | 2002-03-29 | 2003-09-29 | Acs Dobfar Spa | Composizione antitumorale migliorata a base di paclitaxel e metodo per il suo ottenimento |
| US7438722B1 (en) * | 2002-09-20 | 2008-10-21 | Advanced Cardiovascular Systems, Inc. | Method for treatment of restenosis |
| WO2004091506A2 (en) | 2003-04-10 | 2004-10-28 | Ivax Research, Inc. | Taxane-based compositions and methods of use |
| US7989490B2 (en) * | 2004-06-02 | 2011-08-02 | Cordis Corporation | Injectable formulations of taxanes for cad treatment |
-
2004
- 2004-06-02 US US10/858,954 patent/US7989490B2/en not_active Expired - Fee Related
-
2005
- 2005-05-18 EP EP05253046A patent/EP1618879B1/en not_active Expired - Lifetime
- 2005-06-01 JP JP2005161734A patent/JP5615474B2/ja not_active Expired - Fee Related
- 2005-06-02 CA CA2509077A patent/CA2509077C/en not_active Expired - Lifetime
-
2011
- 2011-06-13 US US13/158,610 patent/US9402804B2/en not_active Expired - Fee Related
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