JP2005274573A - ナノ構造表面を有する動的に制御可能な生物学的/化学的検出器 - Google Patents
ナノ構造表面を有する動的に制御可能な生物学的/化学的検出器 Download PDFInfo
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Abstract
【解決手段】第1の実施形態において、流体流は検出器を通過し、したがって、例示的な化学化合物または生物学的種を全体的または部分的に含む粒子を、検出器中のナノ構造の先端上に収集させる。液滴はナノ構造の先端を横切って移動され、したがって、粒子を液体内に吸収する。液滴は所望の位置でナノ構造に浸透させられ、したがって、上記液滴内の化学化合物または生物学的種を、例えば試薬と接触させる。他の実施形態において、流体流は、化学化合物および/または生物学的種が所望のピクセルのナノ柱間に堆積されるように、検出器のナノ構造表面を通過させられる。液滴はその所望のピクセルへ表面を横切って移動され、ピクセルのナノ構造に浸透させられ、したがって、試薬と接触する。
【選択図】図1
Description
Claims (10)
- 上に配置された複数のナノ構造を有する少なくとも1つの第1のナノ構造表面と、
少なくとも1つの第1の液滴と、
少なくとも1つの第1の試薬ピクセルと、
前記少なくとも1つの第1の液滴を、前記少なくとも1つの第1の液滴が前記少なくとも1つの第1の試薬ピクセルと接触するような方法で、前記少なくとも1つの第1のナノ構造表面を横切って移動するための手段と、を含む検出器。 - 移動のための前記手段は前記複数のナノ構造を含み、前記複数のナノ構造におけるナノ構造の密度が、前記少なくとも1つの第1の液滴が最高密度の前記ナノ構造を有する前記少なくとも1つの第1のナノ構造表面上の領域に向かって移動するように変化する請求項1に記載の検出器。
- 移動のための前記手段は、複数の電極のうちの電極の少なくとも1つに電圧を連続的に印加すると液滴が所望の方向に移動するように前記少なくとも1つの第1のナノ構造表面上に配置された前記複数の電極を含む請求項1に記載の検出器。
- 前記少なくとも1つの第1の液滴は試薬の液滴である請求項1に記載の検出器。
- 前記少なくとも1つの第1の液滴は、前記複数のナノ構造の先端上に配置された粒子を吸収するように構成されており、前記ナノ構造は前記少なくとも1つの第1のナノ構造表面上に配置されている請求項1に記載の検出器。
- 前記少なくとも1つの第1の液滴は、前記少なくとも1つの第1のナノ構造表面上のピクセルのアレイ内の所望の試薬ピクセルなど所望の目的場所に前記粒子を搬送するようにさらに構成されている請求項5に記載の検出器。
- 複数のナノ構造表面を有し、該表面の少なくとも1つはその表面上に配置された対応する複数のナノ構造を有する検出器を使用して流体の流れ中の物質を検出するための方法であって、
前記ナノ構造表面の少なくとも一部を介して流体流を通過させる工程と、
前記ナノ構造表面の少なくとも1つの表面上で粒子を収集する工程と、
液滴を、前記液体が前記ナノ構造表面上の所望のピクセルに到達するように前記ナノ構造の一部上を移動させる工程と、
前記液滴を、前記所望のピクセル内のナノ構造間に浸透させる工程と、を含み、
前記液滴を、前記所望のピクセル内のナノ構造間に浸透させる前記工程は、特定の生物学的種または化学化合物の粒子が前記流体流中に配置されているか否かについての少なくとも1つの第1の示度を発生する方法。 - 前記液滴は試薬の液滴である請求項7に記載の方法。
- 前記液滴は、前記複数のナノ構造の先端上に配置された粒子を吸収するように構成されており、前記ナノ構造は前記少なくとも1つのナノ構造表面上に配置されている請求項7に記載の方法。
- 前記浸透操作は音響エネルギーまたは電磁エネルギーの発生源を適用する請求項7に記載の方法。
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US10/806543 | 2004-03-23 | ||
US10/806,543 US7048889B2 (en) | 2004-03-23 | 2004-03-23 | Dynamically controllable biological/chemical detectors having nanostructured surfaces |
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JP2005274573A true JP2005274573A (ja) | 2005-10-06 |
JP2005274573A5 JP2005274573A5 (ja) | 2008-05-08 |
JP4711398B2 JP4711398B2 (ja) | 2011-06-29 |
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JP2006105980A (ja) * | 2004-09-30 | 2006-04-20 | Lucent Technol Inc | 微粒子の分析および操作のためのナノ構造表面 |
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JP2015514991A (ja) * | 2012-04-20 | 2015-05-21 | ヒューレット−パッカード デベロップメント カンパニー エル.ピー.Hewlett‐Packard Development Company, L.P. | 集積化センサ |
JPWO2014010534A1 (ja) * | 2012-07-13 | 2016-06-23 | 東洋製罐株式会社 | 内容物に対する滑り性に優れた包装容器 |
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JP2016197077A (ja) * | 2015-04-06 | 2016-11-24 | 国立大学法人大阪大学 | サンプル検出デバイス用のサンプル捕集装置、及び該サンプル捕集装置を含むサンプル検出デバイス |
Also Published As
Publication number | Publication date |
---|---|
EP1584375B1 (en) | 2008-07-02 |
US20060040375A1 (en) | 2006-02-23 |
DE602005007789D1 (de) | 2008-08-14 |
EP1584375A1 (en) | 2005-10-12 |
US7048889B2 (en) | 2006-05-23 |
JP4711398B2 (ja) | 2011-06-29 |
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