JP4881950B2 - 液体搬送デバイス - Google Patents
液体搬送デバイス Download PDFInfo
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- JP4881950B2 JP4881950B2 JP2008524737A JP2008524737A JP4881950B2 JP 4881950 B2 JP4881950 B2 JP 4881950B2 JP 2008524737 A JP2008524737 A JP 2008524737A JP 2008524737 A JP2008524737 A JP 2008524737A JP 4881950 B2 JP4881950 B2 JP 4881950B2
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- 0 CC[C@@](CC(C)(CC1)[C@]23C=C[C@]12[C@@](*)[C@](C)C3)C(C)(C)C Chemical compound CC[C@@](CC(C)(CC1)[C@]23C=C[C@]12[C@@](*)[C@](C)C3)C(C)(C)C 0.000 description 1
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- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
- F04B—POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
- F04B19/00—Machines or pumps having pertinent characteristics not provided for in, or of interest apart from, groups F04B1/00 - F04B17/00
- F04B19/006—Micropumps
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F33/00—Other mixers; Mixing plants; Combinations of mixers
- B01F33/30—Micromixers
- B01F33/302—Micromixers the materials to be mixed flowing in the form of droplets
- B01F33/3021—Micromixers the materials to be mixed flowing in the form of droplets the components to be mixed being combined in a single independent droplet, e.g. these droplets being divided by a non-miscible fluid or consisting of independent droplets
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F33/00—Other mixers; Mixing plants; Combinations of mixers
- B01F33/30—Micromixers
- B01F33/3031—Micromixers using electro-hydrodynamic [EHD] or electro-kinetic [EKI] phenomena to mix or move the fluids
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
- B01L3/502769—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by multiphase flow arrangements
- B01L3/502784—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by multiphase flow arrangements specially adapted for droplet or plug flow, e.g. digital microfluidics
- B01L3/502792—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by multiphase flow arrangements specially adapted for droplet or plug flow, e.g. digital microfluidics for moving individual droplets on a plate, e.g. by locally altering surface tension
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0809—Geometry, shape and general structure rectangular shaped
- B01L2300/0819—Microarrays; Biochips
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
- B01L2300/0867—Multiple inlets and one sample wells, e.g. mixing, dilution
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/089—Virtual walls for guiding liquids
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/04—Moving fluids with specific forces or mechanical means
- B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
- B01L2400/0406—Moving fluids with specific forces or mechanical means specific forces capillary forces
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/04—Moving fluids with specific forces or mechanical means
- B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
- B01L2400/0415—Moving fluids with specific forces or mechanical means specific forces electrical forces, e.g. electrokinetic
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/04—Moving fluids with specific forces or mechanical means
- B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
- B01L2400/0415—Moving fluids with specific forces or mechanical means specific forces electrical forces, e.g. electrokinetic
- B01L2400/0427—Electrowetting
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- Chemical Kinetics & Catalysis (AREA)
- Dispersion Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Engineering & Computer Science (AREA)
- Physics & Mathematics (AREA)
- Mechanical Engineering (AREA)
- Fluid Mechanics (AREA)
- Analytical Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Hematology (AREA)
- Clinical Laboratory Science (AREA)
- Automatic Analysis And Handling Materials Therefor (AREA)
- Sampling And Sample Adjustment (AREA)
Description
本発明の他の目的、特徴及び利点は添付図面に関する以下の本発明の実施例の記載から明らかになるであろう。
ΔP=γ(1/R1+1/R2)
従って、進行方向側の液体の圧力ΔPaとΔPbは以下で表される。
ΔPa=γ(1/Ra1+1/Ra2)
ΔPb=γ(1/Rb1+1/Rb2)
Rb1<Ra1、Rb2<Ra2であることから、ΔPb>ΔPaとなり液は紙面上で左から右側に移動する。すなわち、液体の搬送方向垂直な面における断面積の差に応じて搬送する力と方向が決まる。凹部は少なくとも一部において、液体搬送方向に垂直な面における断面積に差を有する。この断面積の差は、凹部の中心における搬送方向に垂直な面に対して、凹部の形状が非対称である形状により生じる。
上記記載は実施例についてなされたが、本発明はそれに限らず、本発明の精神と添付の請求の範囲の範囲内で種々の変更および修正をすることができることは当業者に明らかである。
Claims (10)
- 第1基板と、
前記第1基板の一の面に配列された複数の電極と、
前記第1基板の一の面と対面して配置される第2基板と、
前記第2基板の前記第1基板の一の面と対面する面に配置された一つの共通電極と、
前記共通電極の表面の少なくとも一部上に設けられ、複数の凹部と複数の凸部とを表面に具備する絶縁膜と、
前記共通電極と複数の電極に電圧を印加する電圧印加手段を有し、
前記凹部は、一方向に向かって幅が小さくなる、または、少なくとも一部において液体輸送方向の断面積に差を有することを特徴とする液体搬送装置。 - 第1基板と、
前記第1基板の一の面に配列された複数の電極と、
前記第1基板の一の面と対面して配置される第2基板と、
前記第2基板の前記第1基板の一の面と対面する面に配置され、複数の凹部と複数の凸部とを表面に具備する一つの共通電極と、
前記共通電極と複数の電極に電圧を印加する電圧印加手段を有し、
前記凹部は、一方向に向かって幅が小さくなる、または、少なくとも一部において液体輸送方向の断面積に差を有することを特徴とする液体搬送装置。 - 第1基板と、
前記第1基板の一の面に配列された複数の電極と、
前記第1基板の一の面と対面して配置される第2基板と、
前記第2基板の前記第1基板の一の面と対面する面に配置された一つの共通電極と、
前記共通電極の表面の少なくとも一部上に設けられる絶縁膜と、
前記絶縁膜の表面の少なくとも一部上に設けられ、複数の凹部と複数の凸部とを表面に具備する疎水膜と、
前記共通電極と複数の電極に電圧を印加する電圧印加手段を有し、
前記凹部は、一方向に向かって幅が小さくなる、または、少なくとも一部において液体輸送方向の断面積に差を有することを特徴とする液体搬送装置。 - 前記凸部の一部は、前記電極に対面する位置にあることを特徴とする請求項1及び3に記載の液体搬送装置。
- 前記凹部は、凹部の中心において、液体搬送方向に垂直な面に対して実質的に非対称であることを特徴とする請求項1乃至3に記載の液体搬送装置。
- 前記凹部は、前記複数の電極の隣接する一の電極と他の電極との間の領域に対応して配置されることを特徴とする請求項1乃至3に記載の液体搬送装置。
- 光源と検出部とをさらに有し、前記凹部は前記複数の電極の隣接する一の電極と他の電極との間の領域に対応して配置され、前記光源から出射された光は、前記凹部を通過し、前記検出部で検出されることを特徴とする請求項1乃至3記載の液体搬送装置。
- 前記絶縁膜の少なくとも一部の上に位置する疎水膜をさらに有することを特徴とする請求項1記載の液体搬送装置。
- 前記電極と前記共通電極との各々を覆う複数の絶縁膜と、前記複数の絶縁膜の各々の少なくとも一部の上に位置する疎水膜とをさらに有することを特徴とする請求項2記載の液体搬送装置。
- 前記凹部と前記凸部によって被搬送液体を変形させ、前記被搬送液体を混合することを特徴とする請求項1乃至3記載の液体搬送装置。
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2008524737A JP4881950B2 (ja) | 2006-07-10 | 2007-06-15 | 液体搬送デバイス |
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2006188786 | 2006-07-10 | ||
JP2006188786 | 2006-07-10 | ||
JP2008524737A JP4881950B2 (ja) | 2006-07-10 | 2007-06-15 | 液体搬送デバイス |
PCT/JP2007/062080 WO2008007511A1 (fr) | 2006-07-10 | 2007-06-15 | Dispositif de transfert de liquide |
Publications (2)
Publication Number | Publication Date |
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JPWO2008007511A1 JPWO2008007511A1 (ja) | 2009-12-10 |
JP4881950B2 true JP4881950B2 (ja) | 2012-02-22 |
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Application Number | Title | Priority Date | Filing Date |
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JP2008524737A Expired - Fee Related JP4881950B2 (ja) | 2006-07-10 | 2007-06-15 | 液体搬送デバイス |
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Country | Link |
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US (1) | US8128798B2 (ja) |
EP (1) | EP2040082A4 (ja) |
JP (1) | JP4881950B2 (ja) |
CN (1) | CN101490562B (ja) |
WO (1) | WO2008007511A1 (ja) |
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CN101490562B (zh) | 2012-12-19 |
JPWO2008007511A1 (ja) | 2009-12-10 |
US20090321262A1 (en) | 2009-12-31 |
EP2040082A4 (en) | 2014-04-23 |
US8128798B2 (en) | 2012-03-06 |
CN101490562A (zh) | 2009-07-22 |
EP2040082A1 (en) | 2009-03-25 |
WO2008007511A1 (fr) | 2008-01-17 |
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