FR2879946B1 - Dispositif de dispense de gouttes - Google Patents

Dispositif de dispense de gouttes

Info

Publication number
FR2879946B1
FR2879946B1 FR0453211A FR0453211A FR2879946B1 FR 2879946 B1 FR2879946 B1 FR 2879946B1 FR 0453211 A FR0453211 A FR 0453211A FR 0453211 A FR0453211 A FR 0453211A FR 2879946 B1 FR2879946 B1 FR 2879946B1
Authority
FR
France
Prior art keywords
drops
dispenser device
dispenser
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
FR0453211A
Other languages
English (en)
Other versions
FR2879946A1 (fr
Inventor
Yves Fouillet
Dorothee Jary
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Commissariat a lEnergie Atomique et aux Energies Alternatives CEA
Original Assignee
Commissariat a lEnergie Atomique CEA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Commissariat a lEnergie Atomique CEA filed Critical Commissariat a lEnergie Atomique CEA
Priority to FR0453211A priority Critical patent/FR2879946B1/fr
Priority to PCT/FR2005/051131 priority patent/WO2006070162A1/fr
Priority to US11/722,637 priority patent/US7922886B2/en
Priority to JP2007547602A priority patent/JP4824697B2/ja
Priority to EP05848241A priority patent/EP1827694B1/fr
Publication of FR2879946A1 publication Critical patent/FR2879946A1/fr
Application granted granted Critical
Publication of FR2879946B1 publication Critical patent/FR2879946B1/fr
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502769—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by multiphase flow arrangements
    • B01L3/502784—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by multiphase flow arrangements specially adapted for droplet or plug flow, e.g. digital microfluidics
    • B01L3/502792—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by multiphase flow arrangements specially adapted for droplet or plug flow, e.g. digital microfluidics for moving individual droplets on a plate, e.g. by locally altering surface tension
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
    • F04B—POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
    • F04B19/00—Machines or pumps having pertinent characteristics not provided for in, or of interest apart from, groups F04B1/00 - F04B17/00
    • F04B19/006—Micropumps
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06—Fluid handling related problems
    • B01L2200/0605—Metering of fluids
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0809—Geometry, shape and general structure rectangular shaped
    • B01L2300/0816—Cards, e.g. flat sample carriers usually with flow in two horizontal directions
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/089—Virtual walls for guiding liquids
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0415—Moving fluids with specific forces or mechanical means specific forces electrical forces, e.g. electrokinetic
    • B01L2400/0427—Electrowetting
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/02—Burettes; Pipettes
    • B01L3/0241—Drop counters; Drop formers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Clinical Laboratory Science (AREA)
  • Hematology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Analytical Chemistry (AREA)
  • Mechanical Engineering (AREA)
  • General Engineering & Computer Science (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Feeding, Discharge, Calcimining, Fusing, And Gas-Generation Devices (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • Micromachines (AREA)
FR0453211A 2004-12-23 2004-12-23 Dispositif de dispense de gouttes Active FR2879946B1 (fr)

Priority Applications (5)

Application Number Priority Date Filing Date Title
FR0453211A FR2879946B1 (fr) 2004-12-23 2004-12-23 Dispositif de dispense de gouttes
PCT/FR2005/051131 WO2006070162A1 (fr) 2004-12-23 2005-12-22 Dispositif de dispense de gouttes
US11/722,637 US7922886B2 (en) 2004-12-23 2005-12-22 Drop dispenser device
JP2007547602A JP4824697B2 (ja) 2004-12-23 2005-12-22 小滴分配装置
EP05848241A EP1827694B1 (fr) 2004-12-23 2005-12-22 Dispositif de dispense de gouttes

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0453211A FR2879946B1 (fr) 2004-12-23 2004-12-23 Dispositif de dispense de gouttes

Publications (2)

Publication Number Publication Date
FR2879946A1 FR2879946A1 (fr) 2006-06-30
FR2879946B1 true FR2879946B1 (fr) 2007-02-09

Family

ID=34953970

Family Applications (1)

Application Number Title Priority Date Filing Date
FR0453211A Active FR2879946B1 (fr) 2004-12-23 2004-12-23 Dispositif de dispense de gouttes

Country Status (5)

Country Link
US (1) US7922886B2 (fr)
EP (1) EP1827694B1 (fr)
JP (1) JP4824697B2 (fr)
FR (1) FR2879946B1 (fr)
WO (1) WO2006070162A1 (fr)

Families Citing this family (58)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006081558A2 (fr) 2005-01-28 2006-08-03 Duke University Appareils et procedes de manipulation de gouttelettes sur une carte de circuits imprimes
JP2008539759A (ja) 2005-05-11 2008-11-20 ナノリティックス・インコーポレイテッド 多数の温度で生化学的又は化学的な反応を実施する方法及び装置
FR2888912B1 (fr) 2005-07-25 2007-08-24 Commissariat Energie Atomique Procede de commande d'une communication entre deux zones par electromouillage, dispositif comportant des zones isolables les unes des autres et procede de realisation d'un tel dispositif
US8734003B2 (en) * 2005-09-15 2014-05-27 Alcatel Lucent Micro-chemical mixing
US20140193807A1 (en) 2006-04-18 2014-07-10 Advanced Liquid Logic, Inc. Bead manipulation techniques
US9476856B2 (en) 2006-04-13 2016-10-25 Advanced Liquid Logic, Inc. Droplet-based affinity assays
US8637324B2 (en) 2006-04-18 2014-01-28 Advanced Liquid Logic, Inc. Bead incubation and washing on a droplet actuator
US7901947B2 (en) 2006-04-18 2011-03-08 Advanced Liquid Logic, Inc. Droplet-based particle sorting
US8658111B2 (en) * 2006-04-18 2014-02-25 Advanced Liquid Logic, Inc. Droplet actuators, modified fluids and methods
US7851184B2 (en) 2006-04-18 2010-12-14 Advanced Liquid Logic, Inc. Droplet-based nucleic acid amplification method and apparatus
US8980198B2 (en) * 2006-04-18 2015-03-17 Advanced Liquid Logic, Inc. Filler fluids for droplet operations
US7439014B2 (en) 2006-04-18 2008-10-21 Advanced Liquid Logic, Inc. Droplet-based surface modification and washing
US8716015B2 (en) 2006-04-18 2014-05-06 Advanced Liquid Logic, Inc. Manipulation of cells on a droplet actuator
US10078078B2 (en) 2006-04-18 2018-09-18 Advanced Liquid Logic, Inc. Bead incubation and washing on a droplet actuator
US8809068B2 (en) 2006-04-18 2014-08-19 Advanced Liquid Logic, Inc. Manipulation of beads in droplets and methods for manipulating droplets
WO2007123908A2 (fr) 2006-04-18 2007-11-01 Advanced Liquid Logic, Inc. Opérations en puits multiples à base de gouttelettes
US9675972B2 (en) 2006-05-09 2017-06-13 Advanced Liquid Logic, Inc. Method of concentrating beads in a droplet
CN101490562B (zh) * 2006-07-10 2012-12-19 株式会社日立高新技术 液体输送设备
US8685344B2 (en) 2007-01-22 2014-04-01 Advanced Liquid Logic, Inc. Surface assisted fluid loading and droplet dispensing
KR101431778B1 (ko) 2007-02-09 2014-08-20 어드밴스드 리퀴드 로직, 아이엔씨. 자성 비즈를 이용하는 액적 작동기 장치 및 방법
WO2008101194A2 (fr) 2007-02-15 2008-08-21 Advanced Liquid Logic, Inc. Détection de capacité sur un actuateur goutte
US8202686B2 (en) * 2007-03-22 2012-06-19 Advanced Liquid Logic, Inc. Enzyme assays for a droplet actuator
EP2126038B1 (fr) 2007-03-22 2015-01-07 Advanced Liquid Logic, Inc. Essais enzymatique pour actionneur à gouttelettes
AU2008237017B2 (en) * 2007-04-10 2013-10-24 Advanced Liquid Logic, Inc. Droplet dispensing device and methods
WO2009002920A1 (fr) 2007-06-22 2008-12-31 Advanced Liquid Logic, Inc. Amplification d'acide nucléique à base de gouttelette dans un gradient de température
WO2009032863A2 (fr) 2007-09-04 2009-03-12 Advanced Liquid Logic, Inc. Actionneur de gouttelette avec substrat supérieur amélioré
US20100236928A1 (en) * 2007-10-17 2010-09-23 Advanced Liquid Logic, Inc. Multiplexed Detection Schemes for a Droplet Actuator
US20100236929A1 (en) * 2007-10-18 2010-09-23 Advanced Liquid Logic, Inc. Droplet Actuators, Systems and Methods
EP2232535A4 (fr) * 2007-12-10 2016-04-13 Advanced Liquid Logic Inc Configurations d'actionneur de gouttelette et procédés
CN103707643B (zh) * 2007-12-23 2016-06-01 先进液体逻辑公司 液滴致动器配置以及引导液滴操作的方法
FR2930457B1 (fr) * 2008-04-24 2010-06-25 Commissariat Energie Atomique Procede de fabrication de microcanaux reconfigurables
US9206794B2 (en) * 2008-04-28 2015-12-08 Nxp, B.V. Microfluidic pump with metal electrode having variable oxidation state
US8852952B2 (en) 2008-05-03 2014-10-07 Advanced Liquid Logic, Inc. Method of loading a droplet actuator
EP2286228B1 (fr) 2008-05-16 2019-04-03 Advanced Liquid Logic, Inc. Dispositifs et procédés actionneurs de gouttelettes pour manipuler des billes
FR2937690B1 (fr) * 2008-10-28 2010-12-31 Commissariat Energie Atomique Micropome a actionnement par gouttes
WO2010062163A1 (fr) * 2008-11-25 2010-06-03 Miortech Holding B.V. Élément optique d'électromouillage et système de miroir comprenant ledit élément
US8877512B2 (en) * 2009-01-23 2014-11-04 Advanced Liquid Logic, Inc. Bubble formation techniques using physical or chemical features to retain a gas bubble within a droplet actuator
US8926065B2 (en) 2009-08-14 2015-01-06 Advanced Liquid Logic, Inc. Droplet actuator devices and methods
DE102009038469B4 (de) * 2009-08-21 2015-02-12 Advanced Display Technology Ag Anzeigeelement und Verfahren zum Ansteuern eines Anzeigeelementes
JP5610258B2 (ja) * 2009-09-09 2014-10-22 国立大学法人 筑波大学 送液装置
US8846414B2 (en) 2009-09-29 2014-09-30 Advanced Liquid Logic, Inc. Detection of cardiac markers on a droplet actuator
WO2011057197A2 (fr) 2009-11-06 2011-05-12 Advanced Liquid Logic, Inc. Actionneur de gouttelettes intégré pour électrophorèse sur gel et analyse moléculaire
EP2516669B1 (fr) 2009-12-21 2016-10-12 Advanced Liquid Logic, Inc. Analyses d'enzymes sur un diffuseur à gouttelettes
EP2553473A4 (fr) 2010-03-30 2016-08-10 Advanced Liquid Logic Inc Plateforme pour opérations sur des gouttelettes
EP2588322B1 (fr) 2010-06-30 2015-06-17 Advanced Liquid Logic, Inc. Ensembles actionneurs à gouttelettes et leurs procédés de fabrication
CA2833897C (fr) 2011-05-09 2020-05-19 Advanced Liquid Logic, Inc. Retroaction microfluidique utilisant une detection d'impedance
AU2012253595B2 (en) 2011-05-10 2016-10-20 Advanced Liquid Logic, Inc. Enzyme concentration and assays
CN103733059B (zh) 2011-07-06 2016-04-06 先进流体逻辑公司 在微滴执行机构上的试剂储存
US8901043B2 (en) 2011-07-06 2014-12-02 Advanced Liquid Logic, Inc. Systems for and methods of hybrid pyrosequencing
US9513253B2 (en) 2011-07-11 2016-12-06 Advanced Liquid Logic, Inc. Droplet actuators and techniques for droplet-based enzymatic assays
US9446404B2 (en) 2011-07-25 2016-09-20 Advanced Liquid Logic, Inc. Droplet actuator apparatus and system
US8637242B2 (en) 2011-11-07 2014-01-28 Illumina, Inc. Integrated sequencing apparatuses and methods of use
WO2013078216A1 (fr) 2011-11-21 2013-05-30 Advanced Liquid Logic Inc Dosages de la glucose-6-phosphate déshydrogénase
US9223317B2 (en) 2012-06-14 2015-12-29 Advanced Liquid Logic, Inc. Droplet actuators that include molecular barrier coatings
IN2015DN00359A (fr) 2012-06-27 2015-06-12 Advanced Liquid Logic Inc
US9863913B2 (en) 2012-10-15 2018-01-09 Advanced Liquid Logic, Inc. Digital microfluidics cartridge and system for operating a flow cell
JP6463375B2 (ja) 2014-04-16 2019-01-30 アボット・ラボラトリーズＡｂｂｏｔｔ Ｌａｂｏｒａｔｏｒｉｅｓ 液滴アクチュエータ製造装置、システム、および関連方法
FR3127810A1 (fr) 2021-10-01 2023-04-07 Commissariat à l'Energie Atomique et aux Energies Alternatives Procédé de tri de gouttes

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IL69431A (en) 1983-08-04 1987-12-31 Omikron Scient Ltd Liquid delivery system particularly useful as an implantable micro-pump for delivering insulin or other drugs
FI980874A (fi) * 1998-04-20 1999-10-21 Wallac Oy Menetelmä ja laite pienten nestemäärien kemiallisen analyysin suorittamiseksi
FR2794039B1 (fr) * 1999-05-27 2002-05-03 Osmooze Sa Dispositif de formation, de deplacement et de diffusion de petites quantites calibrees de liquides
US7016560B2 (en) * 2001-02-28 2006-03-21 Lightwave Microsystems Corporation Microfluidic control for waveguide optical switches, variable attenuators, and other optical devices
FR2841063B1 (fr) 2002-06-18 2004-09-17 Commissariat Energie Atomique Dispositif de deplacement de petits volumes de liquide le long d'un micro-catenaire par des forces electrostatiques
US6989234B2 (en) * 2002-09-24 2006-01-24 Duke University Method and apparatus for non-contact electrostatic actuation of droplets
US7329545B2 (en) * 2002-09-24 2008-02-12 Duke University Methods for sampling a liquid flow
WO2004058333A1 (fr) * 2002-12-30 2004-07-15 Koninklijke Philips Electronics N.V. Système de distribution de fluide
KR100474851B1 (ko) * 2003-01-15 2005-03-09 삼성전자주식회사 잉크 토출 방법 및 이를 채용한 잉크젯 프린트헤드
FR2872809B1 (fr) * 2004-07-09 2006-09-15 Commissariat Energie Atomique Methode d'adressage d'electrodes
JP2006058031A (ja) * 2004-08-17 2006-03-02 Hitachi High-Technologies Corp 化学分析装置

Also Published As

Publication number Publication date
FR2879946A1 (fr) 2006-06-30
JP4824697B2 (ja) 2011-11-30
US7922886B2 (en) 2011-04-12
EP1827694A1 (fr) 2007-09-05
US20080142376A1 (en) 2008-06-19
WO2006070162A1 (fr) 2006-07-06
JP2008525778A (ja) 2008-07-17
EP1827694B1 (fr) 2013-02-20

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