JP2005179557A5 - - Google Patents
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- Publication number
- JP2005179557A5 JP2005179557A5 JP2003424376A JP2003424376A JP2005179557A5 JP 2005179557 A5 JP2005179557 A5 JP 2005179557A5 JP 2003424376 A JP2003424376 A JP 2003424376A JP 2003424376 A JP2003424376 A JP 2003424376A JP 2005179557 A5 JP2005179557 A5 JP 2005179557A5
- Authority
- JP
- Japan
- Prior art keywords
- phenylene
- group
- difluoro
- ocf
- hydrogen
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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- 229910052739 hydrogen Inorganic materials 0.000 claims description 38
- 239000001257 hydrogen Substances 0.000 claims description 37
- 125000000217 alkyl group Chemical group 0.000 claims description 34
- -1 —N═C ═S Chemical group 0.000 claims description 28
- 229910052736 halogen Inorganic materials 0.000 claims description 24
- 150000002367 halogens Chemical class 0.000 claims description 24
- 150000002431 hydrogen Chemical class 0.000 claims description 24
- 125000004955 1,4-cyclohexylene group Chemical group [H]C1([H])C([H])([H])C([H])([*:1])C([H])([H])C([H])([H])C1([H])[*:2] 0.000 claims description 17
- 125000004432 carbon atom Chemical group C* 0.000 claims description 16
- 229910052731 fluorine Inorganic materials 0.000 claims description 16
- 239000011737 fluorine Substances 0.000 claims description 16
- 125000002947 alkylene group Chemical group 0.000 claims description 14
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 claims description 13
- 125000003545 alkoxy group Chemical group 0.000 claims description 11
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 claims description 11
- PXGOKWXKJXAPGV-UHFFFAOYSA-N Fluorine Chemical compound FF PXGOKWXKJXAPGV-UHFFFAOYSA-N 0.000 claims description 10
- 125000001140 1,4-phenylene group Chemical group [H]C1=C([H])C([*:2])=C([H])C([H])=C1[*:1] 0.000 claims description 7
- 150000001350 alkyl halides Chemical class 0.000 claims description 3
- 150000001875 compounds Chemical class 0.000 claims 34
- 125000005714 2,5- (1,3-dioxanylene) group Chemical group [H]C1([H])OC([H])([*:1])OC([H])([H])C1([H])[*:2] 0.000 claims 10
- 229920000642 polymer Polymers 0.000 claims 10
- 229910052799 carbon Inorganic materials 0.000 claims 7
- 239000004973 liquid crystal related substance Substances 0.000 claims 7
- 125000005732 2,6-difluoro-1,4-phenylene group Chemical group [H]C1=C(F)C([*:1])=C(F)C([H])=C1[*:2] 0.000 claims 6
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 claims 6
- 125000001153 fluoro group Chemical group F* 0.000 claims 6
- HNYOPLTXPVRDBG-UHFFFAOYSA-N barbituric acid Chemical compound O=C1CC(=O)NC(=O)N1 HNYOPLTXPVRDBG-UHFFFAOYSA-N 0.000 claims 1
- 239000007788 liquid Substances 0.000 claims 1
- 230000003287 optical effect Effects 0.000 claims 1
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2003424376A JP4923380B2 (ja) | 2003-12-22 | 2003-12-22 | 低屈折率異方性化合物、組成物およびそれらの重合体または重合体組成物 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2003424376A JP4923380B2 (ja) | 2003-12-22 | 2003-12-22 | 低屈折率異方性化合物、組成物およびそれらの重合体または重合体組成物 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2005179557A JP2005179557A (ja) | 2005-07-07 |
| JP2005179557A5 true JP2005179557A5 (enExample) | 2006-11-30 |
| JP4923380B2 JP4923380B2 (ja) | 2012-04-25 |
Family
ID=34784591
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2003424376A Expired - Fee Related JP4923380B2 (ja) | 2003-12-22 | 2003-12-22 | 低屈折率異方性化合物、組成物およびそれらの重合体または重合体組成物 |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JP4923380B2 (enExample) |
Families Citing this family (50)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20070119007A (ko) * | 2005-04-13 | 2007-12-18 | 아사히 가라스 가부시키가이샤 | 중합성 액정 조성물, 광학 이방성 재료, 광학 소자 및광헤드 장치 |
| US7919648B2 (en) | 2005-12-08 | 2011-04-05 | Chisso Corporation | Lateral α-substituted acrylate compound and polymer thereof |
| JP5163019B2 (ja) * | 2006-09-06 | 2013-03-13 | Ｊｎｃ株式会社 | アルケニルを有するシクロヘキセン誘導体、液晶組成物および液晶表示素子 |
| JP5803076B2 (ja) * | 2009-10-13 | 2015-11-04 | Jnc株式会社 | 重合性液晶化合物ならびにその重合体 |
| JP5962949B2 (ja) * | 2011-11-28 | 2016-08-03 | Dic株式会社 | 重合性液晶化合物 |
| JP6031781B2 (ja) * | 2012-03-01 | 2016-11-24 | Dic株式会社 | 重合性化合物及びそれを用いた液晶組成物 |
| JP5962347B2 (ja) * | 2012-05-08 | 2016-08-03 | Jsr株式会社 | 新規（メタ）アクリル酸エステルおよびその重合体 |
| EP2970121B1 (en) * | 2013-03-15 | 2017-12-13 | Araxes Pharma LLC | Covalent inhibitors of kras g12c |
| UY35464A (es) | 2013-03-15 | 2014-10-31 | Araxes Pharma Llc | Inhibidores covalentes de kras g12c. |
| TWI659021B (zh) | 2013-10-10 | 2019-05-11 | 亞瑞克西斯製藥公司 | Ｋｒａｓ ｇ１２ｃ之抑制劑 |
| JO3556B1 (ar) | 2014-09-18 | 2020-07-05 | Araxes Pharma Llc | علاجات مدمجة لمعالجة السرطان |
| CN104610978B (zh) * | 2015-02-09 | 2017-01-25 | 石家庄诚志永华显示材料有限公司 | 液晶化合物及包含该化合物的液晶介质 |
| EP3260450A4 (en) * | 2015-02-17 | 2018-10-10 | JNC Corporation | Compound having saturated six-membered ring and alkoxy group or alkoxyalkyl group, liquid crystal composition and liquid crystal display element |
| EA201792214A1 (ru) | 2015-04-10 | 2018-01-31 | Араксис Фарма Ллк | Соединения замещенного хиназолина |
| US10428064B2 (en) | 2015-04-15 | 2019-10-01 | Araxes Pharma Llc | Fused-tricyclic inhibitors of KRAS and methods of use thereof |
| WO2016208483A1 (ja) * | 2015-06-25 | 2016-12-29 | Dic株式会社 | 重合性化合物およびそれを使用した液晶表示素子 |
| WO2017007007A1 (ja) * | 2015-07-09 | 2017-01-12 | 富士フイルム株式会社 | 重合性化合物を含む重合性組成物、フィルム、投映像表示用ハーフミラー、および重合性化合物 |
| US10144724B2 (en) | 2015-07-22 | 2018-12-04 | Araxes Pharma Llc | Substituted quinazoline compounds and methods of use thereof |
| EP3356351A1 (en) | 2015-09-28 | 2018-08-08 | Araxes Pharma LLC | Inhibitors of kras g12c mutant proteins |
| EP3356354A1 (en) | 2015-09-28 | 2018-08-08 | Araxes Pharma LLC | Inhibitors of kras g12c mutant proteins |
| EP3356359B1 (en) | 2015-09-28 | 2021-10-20 | Araxes Pharma LLC | Inhibitors of kras g12c mutant proteins |
| EP3356353A1 (en) | 2015-09-28 | 2018-08-08 | Araxes Pharma LLC | Inhibitors of kras g12c mutant proteins |
| EP3356347A1 (en) | 2015-09-28 | 2018-08-08 | Araxes Pharma LLC | Inhibitors of kras g12c mutant proteins |
| EP3356349A1 (en) | 2015-09-28 | 2018-08-08 | Araxes Pharma LLC | Inhibitors of kras g12c mutant proteins |
| WO2017058902A1 (en) | 2015-09-28 | 2017-04-06 | Araxes Pharma Llc | Inhibitors of kras g12c mutant proteins |
| KR20240113606A (ko) | 2015-11-16 | 2024-07-22 | 아락세스 파마 엘엘씨 | 치환된 헤테로사이클릭 그룹을 포함하는 2-치환된 퀴나졸린 화합물 및 이의 사용 방법 |
| TWI693275B (zh) * | 2016-01-20 | 2020-05-11 | 日商捷恩智股份有限公司 | 具有2原子鍵結基與2,3-二氟伸苯基的4環液晶化合物、液晶組成物和液晶顯示元件 |
| TWI744302B (zh) * | 2016-05-19 | 2021-11-01 | 日商捷恩智股份有限公司 | 聚合性組成物、液晶複合體、光學各向異性體、液晶顯示元件及其用途 |
| JP6772549B2 (ja) * | 2016-05-23 | 2020-10-21 | Dic株式会社 | 重合性化合物及び光学異方体 |
| US10646488B2 (en) | 2016-07-13 | 2020-05-12 | Araxes Pharma Llc | Conjugates of cereblon binding compounds and G12C mutant KRAS, HRAS or NRAS protein modulating compounds and methods of use thereof |
| JP6708042B2 (ja) * | 2016-07-27 | 2020-06-10 | Jnc株式会社 | ジフルオロメチレンオキシ基を有する液晶性化合物、液晶組成物および液晶表示素子 |
| CN110036010A (zh) | 2016-09-29 | 2019-07-19 | 亚瑞克西斯制药公司 | Kras g12c突变蛋白的抑制剂 |
| EP3523289A1 (en) | 2016-10-07 | 2019-08-14 | Araxes Pharma LLC | Heterocyclic compounds as inhibitors of ras and methods of use thereof |
| US11136308B2 (en) | 2017-01-26 | 2021-10-05 | Araxes Pharma Llc | Substituted quinazoline and quinazolinone compounds and methods of use thereof |
| WO2018140599A1 (en) | 2017-01-26 | 2018-08-02 | Araxes Pharma Llc | Benzothiophene and benzothiazole compounds and methods of use thereof |
| WO2018140513A1 (en) | 2017-01-26 | 2018-08-02 | Araxes Pharma Llc | 1-(3-(6-(3-hydroxynaphthalen-1-yl)benzofuran-2-yl)azetidin-1yl)prop-2-en-1-one derivatives and similar compounds as kras g12c modulators for treating cancer |
| EP3573954A1 (en) | 2017-01-26 | 2019-12-04 | Araxes Pharma LLC | Fused bicyclic benzoheteroaromatic compounds and methods of use thereof |
| JP7327802B2 (ja) | 2017-01-26 | 2023-08-16 | アラクセス ファーマ エルエルシー | 縮合ヘテロ－ヘテロ二環式化合物およびその使用方法 |
| KR102658093B1 (ko) * | 2017-03-09 | 2024-04-18 | 메르크 파텐트 게엠베하 | 중합성 화합물 및 이의 액정 디스플레이에서의 용도 |
| EP3630745A2 (en) | 2017-05-25 | 2020-04-08 | Araxes Pharma LLC | Covalent inhibitors of kras |
| EP3630747A1 (en) | 2017-05-25 | 2020-04-08 | Araxes Pharma LLC | Quinazoline derivatives as modulators of mutant kras, hras or nras |
| EP3630746A1 (en) | 2017-05-25 | 2020-04-08 | Araxes Pharma LLC | Compounds and methods of use thereof for treatment of cancer |
| CN108690634A (zh) * | 2017-12-08 | 2018-10-23 | 华南师范大学 | 一种棒状液晶及其应用 |
| JP6910527B2 (ja) * | 2018-02-14 | 2021-07-28 | 富士フイルム株式会社 | 重合性液晶組成物、光学異方性膜、光学フィルム、偏光板および画像表示装置 |
| JP6913226B2 (ja) * | 2018-02-14 | 2021-08-04 | 富士フイルム株式会社 | 重合性液晶組成物、光学異方性膜、光学フィルム、偏光板および画像表示装置 |
| JP2021532157A (ja) | 2018-08-01 | 2021-11-25 | アラクセス ファーマ エルエルシー | がんを処置するための複素環式スピロ化合物およびその使用方法 |
| CN111349447A (zh) * | 2018-12-24 | 2020-06-30 | 河北迈尔斯通电子材料有限公司 | 一种含有二氟甲氧基桥键的液晶化合物、制备方法及应用 |
| WO2025013896A1 (ja) | 2023-07-11 | 2025-01-16 | 富士フイルム株式会社 | 組成物、光学異方性層、硬化膜、回折素子 |
| WO2025013901A1 (ja) | 2023-07-11 | 2025-01-16 | 富士フイルム株式会社 | 液晶組成物、光学異方性層、硬化膜、回折素子、化合物 |
| WO2025164722A1 (ja) * | 2024-01-31 | 2025-08-07 | 大日本印刷株式会社 | 化合物、組成物、光学異方体、及び光学素子 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP4165062B2 (ja) * | 2001-12-18 | 2008-10-15 | チッソ株式会社 | ジフルオロメチレンオキシを有する化合物およびその重合体 |
| JP4088863B2 (ja) * | 2002-02-05 | 2008-05-21 | チッソ株式会社 | フマル酸ジエステルおよびその液晶性ポリマー |
| JP4016670B2 (ja) * | 2002-02-20 | 2007-12-05 | チッソ株式会社 | 液晶性ソルビン酸エステルおよびその重合体 |
| JP4039281B2 (ja) * | 2002-03-18 | 2008-01-30 | チッソ株式会社 | シクロプロパン化合物およびその重合体 |
-
2003
- 2003-12-22 JP JP2003424376A patent/JP4923380B2/ja not_active Expired - Fee Related
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