JP2004537595A5 - - Google Patents
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- Publication number
- JP2004537595A5 JP2004537595A5 JP2003519023A JP2003519023A JP2004537595A5 JP 2004537595 A5 JP2004537595 A5 JP 2004537595A5 JP 2003519023 A JP2003519023 A JP 2003519023A JP 2003519023 A JP2003519023 A JP 2003519023A JP 2004537595 A5 JP2004537595 A5 JP 2004537595A5
- Authority
- JP
- Japan
- Prior art keywords
- group
- atom
- saturated
- groups
- carbon atoms
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 125000004432 carbon atom Chemical group C* 0.000 claims 39
- 150000001875 compounds Chemical class 0.000 claims 36
- 229920006395 saturated elastomer Chemical group 0.000 claims 34
- 229910052717 sulfur Inorganic materials 0.000 claims 31
- 125000000217 alkyl group Chemical group 0.000 claims 30
- 125000004434 sulfur atom Chemical group 0.000 claims 29
- BUGBHKTXTAQXES-UHFFFAOYSA-N Selenium Chemical group [Se] BUGBHKTXTAQXES-UHFFFAOYSA-N 0.000 claims 22
- 229910052711 selenium Inorganic materials 0.000 claims 22
- 125000004435 hydrogen atom Chemical group [H]* 0.000 claims 20
- 125000004430 oxygen atom Chemical group O* 0.000 claims 17
- 125000005842 heteroatom Chemical group 0.000 claims 10
- 229910052799 carbon Inorganic materials 0.000 claims 8
- 239000000203 mixture Substances 0.000 claims 4
- 239000008194 pharmaceutical composition Substances 0.000 claims 4
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical group [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 claims 2
- HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 claims 2
- 239000002537 cosmetic Substances 0.000 claims 2
- 230000006698 induction Effects 0.000 claims 2
- 238000004519 manufacturing process Methods 0.000 claims 2
- 230000002438 mitochondrial effect Effects 0.000 claims 2
- 239000011593 sulfur Substances 0.000 claims 2
- WKBOTKDWSSQWDR-UHFFFAOYSA-N Bromine atom Chemical compound [Br] WKBOTKDWSSQWDR-UHFFFAOYSA-N 0.000 claims 1
- 208000024172 Cardiovascular disease Diseases 0.000 claims 1
- ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical compound [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 claims 1
- 208000032928 Dyslipidaemia Diseases 0.000 claims 1
- 102000004190 Enzymes Human genes 0.000 claims 1
- 108090000790 Enzymes Proteins 0.000 claims 1
- PXGOKWXKJXAPGV-UHFFFAOYSA-N Fluorine Chemical compound FF PXGOKWXKJXAPGV-UHFFFAOYSA-N 0.000 claims 1
- 206010020772 Hypertension Diseases 0.000 claims 1
- 208000017170 Lipid metabolism disease Diseases 0.000 claims 1
- 206010028980 Neoplasm Diseases 0.000 claims 1
- 208000008589 Obesity Diseases 0.000 claims 1
- 102000023984 PPAR alpha Human genes 0.000 claims 1
- 102000000536 PPAR gamma Human genes 0.000 claims 1
- 108010016731 PPAR gamma Proteins 0.000 claims 1
- 206010040954 Skin wrinkling Diseases 0.000 claims 1
- 230000004913 activation Effects 0.000 claims 1
- 125000004429 atom Chemical group 0.000 claims 1
- GDTBXPJZTBHREO-UHFFFAOYSA-N bromine Substances BrBr GDTBXPJZTBHREO-UHFFFAOYSA-N 0.000 claims 1
- 229910052794 bromium Inorganic materials 0.000 claims 1
- 201000011510 cancer Diseases 0.000 claims 1
- 229910052801 chlorine Inorganic materials 0.000 claims 1
- 239000000460 chlorine Substances 0.000 claims 1
- 235000012000 cholesterol Nutrition 0.000 claims 1
- 230000007850 degeneration Effects 0.000 claims 1
- 206010012601 diabetes mellitus Diseases 0.000 claims 1
- 235000014113 dietary fatty acids Nutrition 0.000 claims 1
- 230000000694 effects Effects 0.000 claims 1
- 229930195729 fatty acid Natural products 0.000 claims 1
- 239000000194 fatty acid Substances 0.000 claims 1
- 150000004665 fatty acids Chemical class 0.000 claims 1
- 229910052731 fluorine Inorganic materials 0.000 claims 1
- 239000011737 fluorine Substances 0.000 claims 1
- 125000005843 halogen group Chemical group 0.000 claims 1
- 230000002440 hepatic effect Effects 0.000 claims 1
- 230000002401 inhibitory effect Effects 0.000 claims 1
- PNDPGZBMCMUPRI-UHFFFAOYSA-N iodine Chemical compound II PNDPGZBMCMUPRI-UHFFFAOYSA-N 0.000 claims 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 claims 1
- 235000020824 obesity Nutrition 0.000 claims 1
- 238000007254 oxidation reaction Methods 0.000 claims 1
- 230000001590 oxidative effect Effects 0.000 claims 1
- 229910052760 oxygen Inorganic materials 0.000 claims 1
- 230000000858 peroxisomal effect Effects 0.000 claims 1
- 108091008725 peroxisome proliferator-activated receptors alpha Proteins 0.000 claims 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 claims 1
- 230000035755 proliferation Effects 0.000 claims 1
- 208000037803 restenosis Diseases 0.000 claims 1
- 230000009759 skin aging Effects 0.000 claims 1
- 208000017520 skin disease Diseases 0.000 claims 1
- 210000001189 slow twitch fiber Anatomy 0.000 claims 1
- 125000001424 substituent group Chemical group 0.000 claims 1
- 208000011580 syndromic disease Diseases 0.000 claims 1
- UFTFJSFQGQCHQW-UHFFFAOYSA-N triformin Chemical compound O=COCC(OC=O)COC=O UFTFJSFQGQCHQW-UHFFFAOYSA-N 0.000 claims 1
- 210000004881 tumor cell Anatomy 0.000 claims 1
- 230000004614 tumor growth Effects 0.000 claims 1
- 210000003854 type 2 muscle cell Anatomy 0.000 claims 1
- 230000037303 wrinkles Effects 0.000 claims 1
- 0 *SCC(NC(CO)CO)=O Chemical compound *SCC(NC(CO)CO)=O 0.000 description 2
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR0110645A FR2828487B1 (fr) | 2001-08-09 | 2001-08-09 | Nouveaux composes derives d'acides gras, preparation et utilisations |
| PCT/FR2002/002831 WO2003014073A1 (fr) | 2001-08-09 | 2002-08-08 | Composes derives d'acides gras preparation et utilisations |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2004537595A JP2004537595A (ja) | 2004-12-16 |
| JP2004537595A5 true JP2004537595A5 (https=) | 2006-01-05 |
Family
ID=8866413
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2003519023A Pending JP2004537595A (ja) | 2001-08-09 | 2002-08-08 | 脂肪酸誘導体、その製造法及び使用 |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US7375135B2 (https=) |
| EP (1) | EP1673338B1 (https=) |
| JP (1) | JP2004537595A (https=) |
| AT (1) | ATE373638T1 (https=) |
| AU (1) | AU2002342968B2 (https=) |
| CA (1) | CA2456288A1 (https=) |
| CY (1) | CY1107806T1 (https=) |
| DE (1) | DE60222596T2 (https=) |
| DK (1) | DK1673338T3 (https=) |
| ES (1) | ES2292824T3 (https=) |
| FR (1) | FR2828487B1 (https=) |
| PT (1) | PT1673338E (https=) |
| WO (1) | WO2003014073A1 (https=) |
Families Citing this family (41)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NO328803B1 (no) | 2000-03-03 | 2010-05-18 | Thia Medica | Nye fettsyreanaloger |
| FR2828487B1 (fr) | 2001-08-09 | 2005-05-27 | Genfit S A | Nouveaux composes derives d'acides gras, preparation et utilisations |
| WO2004000854A1 (en) * | 2002-06-20 | 2003-12-31 | Ic Vec Limited | Sulfur-containing phospholipid derivatives |
| FR2850650B1 (fr) * | 2003-01-31 | 2005-03-25 | Genfit S A | Utilisation therapeutique d'acylglycerols et de leurs analogues azotes et sulfures |
| FR2850870B1 (fr) * | 2003-02-12 | 2006-07-28 | Genfit S A | Utilisation therapeutique de glycerols acyles et de leurs analogues azotes et sulfures |
| FR2850869B1 (fr) * | 2003-02-12 | 2005-03-25 | Genfit S A | Utilisations d'aminopropanediols acyles et de leurs analogues azotes et sulfures |
| FR2853834B1 (fr) * | 2003-04-17 | 2008-08-15 | Vincience | Composition cosmetique ou pharmaceutique comprenant l'association d'au moins un diacyglycerol et d'au moins un alcool gras |
| FR2858216B1 (fr) * | 2003-07-31 | 2008-04-04 | Oreal | Composition contenant un 2-thioacetamide, son utilisation pour stimuler la pousse des fibres keratiniques et/ou freiner leur chute |
| RU2261705C1 (ru) * | 2004-01-29 | 2005-10-10 | Медведев Илья Николаевич | Способ лечения тромбоцитопатии при метаболическом синдроме |
| RU2388490C2 (ru) * | 2004-07-19 | 2010-05-10 | Тиа Медика Ас | Композиция, содержащая растительный или рыбий жир, и соединения, содержащие неокисляющиеся структурные элементы жирных кислот |
| NZ553260A (en) * | 2004-07-19 | 2010-12-24 | Thia Medica As | Composition comprising protein material and non-oxidizable fatty acid entities |
| DE102006019907A1 (de) * | 2006-04-28 | 2007-10-31 | Müller-Enoch, Dieter, Prof. Dr. | Verwendung von substituierten Glycerinderivaten zur Herstellung einer pharmazeutischen Zubereitung |
| DE102007051338A1 (de) * | 2007-10-26 | 2009-04-30 | Müller-Enoch, Dieter, Prof. Dr. | Verwendung von substituierten Glycerinderivaten zur Herstellung einer pharmazeutischen Zubereitung zur Behandlung und zur Vorbeugung von Dyslipidämien |
| JP5620272B2 (ja) | 2007-11-09 | 2014-11-05 | プロノヴァ・バイオファーマ・ノルゲ・アーエスＰｒｏｎｏｖａ ＢｉｏＰｈａｒｍａ ＮｏｒｇｅＡＳ | 化粧品において，食品サプリメントとして，または医薬品として用いるための脂質化合物 |
| EP2147910A1 (en) | 2008-07-15 | 2010-01-27 | Pronova BioPharma Norge AS | Novel lipid compounds |
| SG175401A1 (en) | 2009-05-08 | 2011-12-29 | Pronova Biopharma Norge As | Polyunsaturated fatty acids for the treatment of diseases related to cardiovascular, metabolic and inflammatory disease areas |
| EP2445494A4 (en) * | 2009-06-24 | 2012-12-12 | Univ Koebenhavn | TREATMENT OF INSULIN RESISTANCE AND OBESITY BY STIMULATING GLP-1 RELEASE |
| MY170076A (en) | 2010-11-05 | 2019-07-03 | Pronova Biopharma Norge As | Methods of treatment using lipid compounds |
| WO2014132134A1 (en) | 2013-02-28 | 2014-09-04 | Pronova Biopharma Norge As | A composition comprising a lipid compound, a triglyceride, and a surfactant, and methods of using the same |
| CA2904898C (en) | 2013-03-11 | 2019-10-15 | Jan Remmereit | Lipid compositions containing bioactive fatty acids |
| AU2014229506B2 (en) | 2013-03-11 | 2017-04-13 | Nobesita As | Natural lipids containing non-oxidizable fatty acids |
| US9744542B2 (en) | 2013-07-29 | 2017-08-29 | Apeel Technology, Inc. | Agricultural skin grafting |
| BR112017023164A2 (en) | 2015-04-28 | 2018-07-24 | Pronova Biopharma Norge As | and method of preventing and / or treating non-alcoholic steatohepatitis in an individual in need thereof |
| EP3673738B1 (en) | 2015-05-20 | 2024-02-28 | Apeel Technology, Inc. | Plant extract compositions and methods of preparation thereof |
| CN108135188B (zh) | 2015-09-16 | 2022-08-05 | 阿比尔技术公司 | 用于分子涂层的前体化合物 |
| FR3044556B1 (fr) | 2015-12-08 | 2019-10-18 | Pierre Fabre Dermo-Cosmetique | Utilisation de diglyceride 1,3 dans une composition topique pour lutter contre la fragilisation de la barriere cutanee |
| WO2017100636A1 (en) | 2015-12-10 | 2017-06-15 | Apeel Technology, Inc. | Plant extract compositions for forming protective coatings |
| WO2017132281A1 (en) | 2016-01-26 | 2017-08-03 | Apeel Technology, Inc. | Method for preparing and preserving sanitized products |
| WO2018094269A1 (en) | 2016-11-17 | 2018-05-24 | Apeel Technology, Inc. | Compositions formed from plant extracts and methods of preparation thereof |
| AU2018354090B2 (en) | 2017-10-23 | 2024-10-24 | Epitracker, Inc. | Fatty acid analogs and their use in the treatment of conditions related to metabolic syndrome |
| HRP20241643T1 (hr) | 2017-12-06 | 2025-02-14 | Basf As | Derivati masnih kiselina za liječenje nealkoholnog steatohepatitisa |
| EP3793560A4 (en) * | 2018-05-16 | 2022-03-23 | Epitracker, Inc. | COMPOSITIONS AND METHODS FOR DIAGNOSIS AND TREATMENT OF AGING-RELATED CONDITIONS |
| AU2019274431B2 (en) | 2018-05-23 | 2025-03-13 | Epitracker, Inc. | Compositions and methods for diagnosis and treatment of conditions related to the quality of aging and longevity |
| US12245605B2 (en) | 2018-09-05 | 2025-03-11 | Apeel Technology, Inc. | Compounds and formulations for protective coatings |
| EP3908374A4 (en) | 2019-01-09 | 2022-12-28 | Epitracker, Inc. | COMPOSITIONS AND METHODS FOR DIAGNOSIS AND TREATMENT OF NEURODEGENERATIVE DISEASES |
| WO2020180814A1 (en) | 2019-03-04 | 2020-09-10 | Epitracker, Inc. | Fatty acid analogs and their use in the treatment of cognitive impairment, behavioral conditions, and chronic pain |
| US11641865B2 (en) | 2020-03-04 | 2023-05-09 | Apeel Technology, Inc. | Compounds and formulations for protective coatings |
| MX2023004343A (es) | 2020-10-30 | 2023-05-08 | Apeel Tech Inc | Composiciones y metodos de preparacion de las mismas. |
| EP4398731A1 (en) | 2021-09-08 | 2024-07-17 | Apeel Technology, Inc. | Compounds and formulations for protective coatings |
| EP4426130A1 (en) | 2021-11-03 | 2024-09-11 | Epitracker, Inc. | Pentadecanoylcarnitine for treatment of conditions related to the quality of aging and longevity |
| US12133863B1 (en) * | 2023-06-07 | 2024-11-05 | King Saud University | Green synthesis of silver nanoparticles encapsulated in a nanostructured lipid carrier |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2010154A (en) * | 1933-06-27 | 1935-08-06 | Herbert S Kreighbaum | Ether acid ester of polyhydric alcohols |
| GB1271179A (en) * | 1969-06-11 | 1972-04-19 | Mitsubishi Petrochemical Co | Polyolefin resin composition |
| JPS5738616B2 (https=) * | 1974-06-19 | 1982-08-17 | ||
| US4134770A (en) * | 1976-09-22 | 1979-01-16 | Mitsubishi Paper Mills, Ltd. | Gelatin-containing photographic layer incorporated with hardener |
| IL59407A (en) * | 1979-03-06 | 1983-12-30 | Sanofi Sa | Di-n-propylacetic acid diesters of glycerol,their preparation and pharmaceutical compositions containing them |
| JPS5782573A (en) * | 1980-11-05 | 1982-05-24 | Matsumoto Yushi Seiyaku Kk | Smoothening treatment agent for thermoplastic synthetic fiber |
| GB8813012D0 (en) | 1988-06-02 | 1988-07-06 | Norsk Hydro As | Non-b-oxidizable fatty acid analogues to reduce concentration of cholesterol & triglycerides in blood of mammals |
| WO1991003542A1 (fr) * | 1989-09-11 | 1991-03-21 | Kao Corporation | Composition de blanchiment |
| NO952796D0 (no) | 1995-07-14 | 1995-07-14 | Rolf Berge | Fettsyre analoger med ikkeoksyderbart B-sete, fremstilling og anvendelse i krapeutiske preparater |
| US5885595A (en) * | 1996-05-13 | 1999-03-23 | Elizabeth Arden Co., Division Of Conopco, Inc. | Cosmetic composition with a retinol fatty acid ester |
| PT1007509E (pt) | 1997-08-29 | 2004-07-30 | Univ Johns Hopkins | Compostos antimicrobioticos |
| JP2000169443A (ja) | 1998-10-02 | 2000-06-20 | Sankyo Co Ltd | ジチオ―ル誘導体 |
| US6117904A (en) * | 1999-09-03 | 2000-09-12 | Murphy; Donald M. | Treatment of pruritus |
| FR2828487B1 (fr) | 2001-08-09 | 2005-05-27 | Genfit S A | Nouveaux composes derives d'acides gras, preparation et utilisations |
| WO2004000854A1 (en) | 2002-06-20 | 2003-12-31 | Ic Vec Limited | Sulfur-containing phospholipid derivatives |
| FR2850650B1 (fr) | 2003-01-31 | 2005-03-25 | Genfit S A | Utilisation therapeutique d'acylglycerols et de leurs analogues azotes et sulfures |
| FR2850870B1 (fr) | 2003-02-12 | 2006-07-28 | Genfit S A | Utilisation therapeutique de glycerols acyles et de leurs analogues azotes et sulfures |
| FR2850969B1 (fr) | 2003-02-12 | 2005-03-25 | Genfit S A | Aminopropanediols acyles et analogues et leurs utilisations therapeutiques |
| FR2850869B1 (fr) | 2003-02-12 | 2005-03-25 | Genfit S A | Utilisations d'aminopropanediols acyles et de leurs analogues azotes et sulfures |
-
2001
- 2001-08-09 FR FR0110645A patent/FR2828487B1/fr not_active Expired - Fee Related
-
2002
- 2002-08-08 US US10/484,350 patent/US7375135B2/en not_active Expired - Fee Related
- 2002-08-08 AT AT02779622T patent/ATE373638T1/de not_active IP Right Cessation
- 2002-08-08 EP EP02779622A patent/EP1673338B1/fr not_active Expired - Lifetime
- 2002-08-08 ES ES02779622T patent/ES2292824T3/es not_active Expired - Lifetime
- 2002-08-08 WO PCT/FR2002/002831 patent/WO2003014073A1/fr not_active Ceased
- 2002-08-08 CA CA002456288A patent/CA2456288A1/fr not_active Abandoned
- 2002-08-08 AU AU2002342968A patent/AU2002342968B2/en not_active Ceased
- 2002-08-08 PT PT02779622T patent/PT1673338E/pt unknown
- 2002-08-08 JP JP2003519023A patent/JP2004537595A/ja active Pending
- 2002-08-08 DK DK02779622T patent/DK1673338T3/da active
- 2002-08-08 DE DE60222596T patent/DE60222596T2/de not_active Expired - Fee Related
-
2007
- 2007-11-16 CY CY20071101482T patent/CY1107806T1/el unknown
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