FR2828487B1 - Nouveaux composes derives d'acides gras, preparation et utilisations - Google Patents

Nouveaux composes derives d'acides gras, preparation et utilisations

Info

Publication number
FR2828487B1
FR2828487B1 FR0110645A FR0110645A FR2828487B1 FR 2828487 B1 FR2828487 B1 FR 2828487B1 FR 0110645 A FR0110645 A FR 0110645A FR 0110645 A FR0110645 A FR 0110645A FR 2828487 B1 FR2828487 B1 FR 2828487B1
Authority
FR
France
Prior art keywords
preparation
fatty acids
novel compounds
compounds derived
alkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR0110645A
Other languages
English (en)
French (fr)
Other versions
FR2828487A1 (fr
Inventor
Fruchart Jamila Najib
Bertrand Karine Caumont
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Genfit SA
Original Assignee
Genfit SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to FR0110645A priority Critical patent/FR2828487B1/fr
Application filed by Genfit SA filed Critical Genfit SA
Priority to DK02779622T priority patent/DK1673338T3/da
Priority to ES02779622T priority patent/ES2292824T3/es
Priority to EP02779622A priority patent/EP1673338B1/fr
Priority to AT02779622T priority patent/ATE373638T1/de
Priority to PT02779622T priority patent/PT1673338E/pt
Priority to PCT/FR2002/002831 priority patent/WO2003014073A1/fr
Priority to SI200230624T priority patent/SI1673338T1/sl
Priority to JP2003519023A priority patent/JP2004537595A/ja
Priority to AU2002342968A priority patent/AU2002342968B2/en
Priority to CA002456288A priority patent/CA2456288A1/fr
Priority to DE60222596T priority patent/DE60222596T2/de
Priority to US10/484,350 priority patent/US7375135B2/en
Publication of FR2828487A1 publication Critical patent/FR2828487A1/fr
Application granted granted Critical
Publication of FR2828487B1 publication Critical patent/FR2828487B1/fr
Priority to CY20071101482T priority patent/CY1107806T1/el
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
    • C07C323/51—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C323/60—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton with the carbon atom of at least one of the carboxyl groups bound to nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
    • C07C323/51—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C323/52—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C327/00—Thiocarboxylic acids
    • C07C327/20—Esters of monothiocarboxylic acids
    • C07C327/28—Esters of monothiocarboxylic acids having sulfur atoms of esterified thiocarboxyl groups bound to carbon atoms of hydrocarbon radicals substituted by singly-bound oxygen atoms

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Diabetes (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Vascular Medicine (AREA)
  • Dermatology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Fats And Perfumes (AREA)
  • Cosmetics (AREA)
FR0110645A 2001-08-09 2001-08-09 Nouveaux composes derives d'acides gras, preparation et utilisations Expired - Fee Related FR2828487B1 (fr)

Priority Applications (14)

Application Number Priority Date Filing Date Title
FR0110645A FR2828487B1 (fr) 2001-08-09 2001-08-09 Nouveaux composes derives d'acides gras, preparation et utilisations
CA002456288A CA2456288A1 (fr) 2001-08-09 2002-08-08 Composes derives d'acides gras preparation et utilisations
EP02779622A EP1673338B1 (fr) 2001-08-09 2002-08-08 Composes derives d'acides gras preparation et utilisations
AT02779622T ATE373638T1 (de) 2001-08-09 2002-08-08 Fettsäureverbindungen und deren herstellung und verwendungen
PT02779622T PT1673338E (pt) 2001-08-09 2002-08-08 Compostos derivados de ácidos gordos, preparação e utilizações
PCT/FR2002/002831 WO2003014073A1 (fr) 2001-08-09 2002-08-08 Composes derives d'acides gras preparation et utilisations
SI200230624T SI1673338T1 (sl) 2001-08-09 2002-08-08 Spojine maščobne kisline, priprava in njihova uporaba
JP2003519023A JP2004537595A (ja) 2001-08-09 2002-08-08 脂肪酸誘導体、その製造法及び使用
DK02779622T DK1673338T3 (da) 2001-08-09 2002-08-08 Forbindelser afledt af fedtsyrer, fremstilling og anvendelse
ES02779622T ES2292824T3 (es) 2001-08-09 2002-08-08 Compuestos derivados de acidos grasos, preparacion y utilizaciones.
DE60222596T DE60222596T2 (de) 2001-08-09 2002-08-08 Fettsäureverbindungen und deren herstellung und verwendungen
US10/484,350 US7375135B2 (en) 2001-08-09 2002-08-08 Fatty acid derivatives; preparation and uses thereof
AU2002342968A AU2002342968B2 (en) 2001-08-09 2002-08-08 Fatty acid compounds, preparation and uses thereof
CY20071101482T CY1107806T1 (el) 2001-08-09 2007-11-16 Ενωσεις παραγωγα λιπαρων οξεων, παρασκευη και χρησεις τους

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0110645A FR2828487B1 (fr) 2001-08-09 2001-08-09 Nouveaux composes derives d'acides gras, preparation et utilisations

Publications (2)

Publication Number Publication Date
FR2828487A1 FR2828487A1 (fr) 2003-02-14
FR2828487B1 true FR2828487B1 (fr) 2005-05-27

Family

ID=8866413

Family Applications (1)

Application Number Title Priority Date Filing Date
FR0110645A Expired - Fee Related FR2828487B1 (fr) 2001-08-09 2001-08-09 Nouveaux composes derives d'acides gras, preparation et utilisations

Country Status (13)

Country Link
US (1) US7375135B2 (https=)
EP (1) EP1673338B1 (https=)
JP (1) JP2004537595A (https=)
AT (1) ATE373638T1 (https=)
AU (1) AU2002342968B2 (https=)
CA (1) CA2456288A1 (https=)
CY (1) CY1107806T1 (https=)
DE (1) DE60222596T2 (https=)
DK (1) DK1673338T3 (https=)
ES (1) ES2292824T3 (https=)
FR (1) FR2828487B1 (https=)
PT (1) PT1673338E (https=)
WO (1) WO2003014073A1 (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2261705C1 (ru) * 2004-01-29 2005-10-10 Медведев Илья Николаевич Способ лечения тромбоцитопатии при метаболическом синдроме

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FR2828487B1 (fr) 2001-08-09 2005-05-27 Genfit S A Nouveaux composes derives d'acides gras, preparation et utilisations
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FR2850650B1 (fr) * 2003-01-31 2005-03-25 Genfit S A Utilisation therapeutique d'acylglycerols et de leurs analogues azotes et sulfures
FR2850870B1 (fr) * 2003-02-12 2006-07-28 Genfit S A Utilisation therapeutique de glycerols acyles et de leurs analogues azotes et sulfures
FR2850869B1 (fr) * 2003-02-12 2005-03-25 Genfit S A Utilisations d'aminopropanediols acyles et de leurs analogues azotes et sulfures
FR2853834B1 (fr) * 2003-04-17 2008-08-15 Vincience Composition cosmetique ou pharmaceutique comprenant l'association d'au moins un diacyglycerol et d'au moins un alcool gras
FR2858216B1 (fr) * 2003-07-31 2008-04-04 Oreal Composition contenant un 2-thioacetamide, son utilisation pour stimuler la pousse des fibres keratiniques et/ou freiner leur chute
RU2388490C2 (ru) * 2004-07-19 2010-05-10 Тиа Медика Ас Композиция, содержащая растительный или рыбий жир, и соединения, содержащие неокисляющиеся структурные элементы жирных кислот
JP2008506774A (ja) * 2004-07-19 2008-03-06 ティア メディカ アクスイェ セルスカプ タンパク質材料と非酸化性脂肪酸体を含む組成物
DE102006019907A1 (de) * 2006-04-28 2007-10-31 Müller-Enoch, Dieter, Prof. Dr. Verwendung von substituierten Glycerinderivaten zur Herstellung einer pharmazeutischen Zubereitung
DE102007051338A1 (de) * 2007-10-26 2009-04-30 Müller-Enoch, Dieter, Prof. Dr. Verwendung von substituierten Glycerinderivaten zur Herstellung einer pharmazeutischen Zubereitung zur Behandlung und zur Vorbeugung von Dyslipidämien
WO2009061208A1 (en) 2007-11-09 2009-05-14 Pronova Biopharma Norge As Lipid compounds for use in cosmetic products, as food supplement or as a medicament
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BRPI1015120B8 (pt) 2009-05-08 2022-02-15 Basf As Composto lipídico alfa-substituídos, derivados de ácidos graxos beta-oxo poli-insaturados, composição farmacêutica e lipídica e métodos para produzir composto lipídico e ácido 2-((5z,8z,11z,14z,17z)-icosa-5,8,11,14,17-pentaeniloxi)butanóico
WO2010149170A1 (en) * 2009-06-24 2010-12-29 Københavns Universitet Treatment of insulin resistance and obesity by stimulating glp-1 release
ES2618604T3 (es) 2010-11-05 2017-06-21 Pronova Biopharma Norge As Métodos de tratamiento usando compuestos lipídicos
MX377728B (es) 2013-02-28 2025-03-11 Pronova Biopharma Norge As Composición que comprende un compuesto lípido, un triglicerido y un tensioactivo, y métodos de uso de la misma.
CA2904898C (en) 2013-03-11 2019-10-15 Jan Remmereit Lipid compositions containing bioactive fatty acids
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US9744542B2 (en) 2013-07-29 2017-08-29 Apeel Technology, Inc. Agricultural skin grafting
ES2980790T3 (es) 2015-04-28 2024-10-03 Basf As Acidos grasos estructuralmente mejorados que contienen azufre para su uso en el tratamiento de la esteatohepatitis no alcohólica
WO2016187581A1 (en) 2015-05-20 2016-11-24 Apeel Technology, Inc. Plant extract compositions and methods of preparation thereof
WO2017048951A1 (en) 2015-09-16 2017-03-23 Apeel Technology, Inc. Precursor compounds for molecular coatings
FR3044556B1 (fr) 2015-12-08 2019-10-18 Pierre Fabre Dermo-Cosmetique Utilisation de diglyceride 1,3 dans une composition topique pour lutter contre la fragilisation de la barriere cutanee
JP6549326B2 (ja) 2015-12-10 2019-07-24 アピール テクノロジー，インコーポレイテッド 保護コーティングを形成するための植物抽出物組成物
CN109068627B (zh) 2016-01-26 2022-03-18 阿比尔技术公司 用于制备和保存消毒产品的方法
EP3541192B1 (en) 2016-11-17 2025-06-25 Apeel Technology, Inc. Methods of preparing fatty acid esters from crosslinked polyesters
KR102701244B1 (ko) 2017-10-23 2024-09-02 에피트래커, 인코포레이티드 지방산 유사체 및 대사 증후군 관련 병태 치료에서의 그의 용도
IL308604B2 (en) 2017-12-06 2025-08-01 Basf As Fatty acid derivatives for treating non-alcoholic steatohepatitis
AU2019271067B2 (en) * 2018-05-16 2023-08-03 Epitracker, Inc. Compositions and methods for diagnosis and treatment of conditions related to aging
AU2019274431B2 (en) 2018-05-23 2025-03-13 Epitracker, Inc. Compositions and methods for diagnosis and treatment of conditions related to the quality of aging and longevity
US12245605B2 (en) 2018-09-05 2025-03-11 Apeel Technology, Inc. Compounds and formulations for protective coatings
EP3908374A4 (en) 2019-01-09 2022-12-28 Epitracker, Inc. COMPOSITIONS AND METHODS FOR DIAGNOSIS AND TREATMENT OF NEURODEGENERATIVE DISEASES
JP7404382B2 (ja) 2019-03-04 2023-12-25 エピトラッカー インコーポレイテッド 脂肪酸アナログ、ならびに認知機能障害、行動症状および慢性疼痛の処置におけるそれらの使用
US11641865B2 (en) 2020-03-04 2023-05-09 Apeel Technology, Inc. Compounds and formulations for protective coatings
US11827591B2 (en) 2020-10-30 2023-11-28 Apeel Technology, Inc. Compositions and methods of preparation thereof
CN118159138A (zh) 2021-09-08 2024-06-07 阿比尔技术公司 用于保护性涂层的化合物和制剂
EP4426130A1 (en) 2021-11-03 2024-09-11 Epitracker, Inc. Pentadecanoylcarnitine for treatment of conditions related to the quality of aging and longevity
US12133863B1 (en) * 2023-06-07 2024-11-05 King Saud University Green synthesis of silver nanoparticles encapsulated in a nanostructured lipid carrier

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NZ537762A (en) 2002-06-20 2007-02-23 Thia Medica As Sulfur-containing phospholipid derivatives
FR2850650B1 (fr) 2003-01-31 2005-03-25 Genfit S A Utilisation therapeutique d'acylglycerols et de leurs analogues azotes et sulfures
FR2850870B1 (fr) 2003-02-12 2006-07-28 Genfit S A Utilisation therapeutique de glycerols acyles et de leurs analogues azotes et sulfures
FR2850969B1 (fr) 2003-02-12 2005-03-25 Genfit S A Aminopropanediols acyles et analogues et leurs utilisations therapeutiques
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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2261705C1 (ru) * 2004-01-29 2005-10-10 Медведев Илья Николаевич Способ лечения тромбоцитопатии при метаболическом синдроме

Also Published As

Publication number Publication date
CA2456288A1 (fr) 2003-02-20
US7375135B2 (en) 2008-05-20
DE60222596T2 (de) 2008-07-24
WO2003014073A1 (fr) 2003-02-20
DE60222596D1 (de) 2007-10-31
EP1673338B1 (fr) 2007-09-19
US20040192908A1 (en) 2004-09-30
DK1673338T3 (da) 2008-01-14
AU2002342968B2 (en) 2008-05-15
PT1673338E (pt) 2007-12-12
ATE373638T1 (de) 2007-10-15
FR2828487A1 (fr) 2003-02-14
ES2292824T3 (es) 2008-03-16
EP1673338A1 (fr) 2006-06-28
JP2004537595A (ja) 2004-12-16
CY1107806T1 (el) 2013-06-19

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