JP2005512965A5 - - Google Patents
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- Publication number
- JP2005512965A5 JP2005512965A5 JP2003530311A JP2003530311A JP2005512965A5 JP 2005512965 A5 JP2005512965 A5 JP 2005512965A5 JP 2003530311 A JP2003530311 A JP 2003530311A JP 2003530311 A JP2003530311 A JP 2003530311A JP 2005512965 A5 JP2005512965 A5 JP 2005512965A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutical composition
- topiramate
- effective amount
- therapeutically effective
- alkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 239000008194 pharmaceutical composition Substances 0.000 claims 15
- 125000000217 alkyl group Chemical group 0.000 claims 12
- KJADKKWYZYXHBB-XBWDGYHZSA-N Topiramic acid Chemical compound C1O[C@@]2(COS(N)(=O)=O)OC(C)(C)O[C@H]2[C@@H]2OC(C)(C)O[C@@H]21 KJADKKWYZYXHBB-XBWDGYHZSA-N 0.000 claims 9
- 239000001257 hydrogen Substances 0.000 claims 9
- 229910052739 hydrogen Inorganic materials 0.000 claims 9
- 229960004394 topiramate Drugs 0.000 claims 9
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 claims 6
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 claims 6
- 150000001875 compounds Chemical class 0.000 claims 6
- 239000001301 oxygen Substances 0.000 claims 6
- 229910052760 oxygen Inorganic materials 0.000 claims 6
- 206010038743 Restlessness Diseases 0.000 claims 5
- 208000011580 syndromic disease Diseases 0.000 claims 5
- 125000002009 alkene group Chemical group 0.000 claims 3
- 125000000113 cyclohexyl group Chemical group [H]C1([H])C([H])([H])C([H])([H])C([H])(*)C([H])([H])C1([H])[H] 0.000 claims 3
- 125000001511 cyclopentyl group Chemical group [H]C1([H])C([H])([H])C([H])([H])C([H])(*)C1([H])[H] 0.000 claims 3
- 150000002431 hydrogen Chemical class 0.000 claims 3
- -1 methylenedioxy group Chemical group 0.000 claims 3
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 claims 3
- 208000016285 Movement disease Diseases 0.000 claims 2
- 208000008705 Nocturnal Myoclonus Syndrome Diseases 0.000 claims 2
- 229940079593 drug Drugs 0.000 claims 2
- 239000003814 drug Substances 0.000 claims 2
- 208000023515 periodic limb movement disease Diseases 0.000 claims 2
- 208000005793 Restless legs syndrome Diseases 0.000 claims 1
- 208000019116 sleep disease Diseases 0.000 claims 1
- 0 *CCC1C(*)C(*)C(*)C*1 Chemical compound *CCC1C(*)C(*)C(*)C*1 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US32444001P | 2001-09-24 | 2001-09-24 | |
| US10/252,814 US20030092759A1 (en) | 2001-09-24 | 2002-09-23 | Anticonvulsant derivatives useful for the treatment of restless limb syndrome and periodic limb movement disorder |
| PCT/US2002/030194 WO2003026676A1 (en) | 2001-09-24 | 2002-09-23 | Anticonvulsant derivatives useful for the treatment of restless limb syndrome and periodic limb movement disorder |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2005512965A JP2005512965A (ja) | 2005-05-12 |
| JP2005512965A5 true JP2005512965A5 (https=) | 2006-01-05 |
Family
ID=23263595
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2003530311A Withdrawn JP2005512965A (ja) | 2001-09-24 | 2002-09-23 | 不穏四肢症候群および定期的四肢運動障害の処置に有用な抗痙攣誘導体 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20030092759A1 (https=) |
| EP (1) | EP1429787A1 (https=) |
| JP (1) | JP2005512965A (https=) |
| AU (1) | AU2002336765B2 (https=) |
| CA (1) | CA2461539A1 (https=) |
| MX (1) | MXPA04002709A (https=) |
| NZ (1) | NZ531871A (https=) |
| WO (1) | WO2003026676A1 (https=) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1041987B1 (en) | 1997-12-22 | 2006-04-19 | Euro-Celtique S.A. | Pharmaceutical oral dosage form comprising a combination of an opioid agonist and naltrexone |
| US6375957B1 (en) | 1997-12-22 | 2002-04-23 | Euro-Celtique, S.A. | Opioid agonist/opioid antagonist/acetaminophen combinations |
| EP1387673B1 (en) | 2001-05-11 | 2010-12-29 | Endo Pharmaceuticals Inc. | Abuse-resistant controlled-release opioid dosage form |
| HUE032656T2 (en) * | 2002-04-05 | 2017-10-30 | Euro Celtique Sa | Pharmaceutical composition containing oxicodone and naloxone |
| US20040115263A1 (en) * | 2002-08-26 | 2004-06-17 | Robertson David W. | Use of bupropion for treating restless legs syndrome |
| AU2004274002B2 (en) | 2003-09-17 | 2011-04-28 | Arbor Pharmaceuticals, Llc | Treating or preventing restless legs syndrome using prodrugs of GABA analogs |
| EP1604666A1 (en) * | 2004-06-08 | 2005-12-14 | Euro-Celtique S.A. | Opioids for the treatment of the Chronic Obstructive Pulmonary Disease (COPD) |
| EP1604667A1 (en) * | 2004-06-08 | 2005-12-14 | Euro-Celtique S.A. | Opioids for the treatment of the restless leg syndrome |
| GEP20105052B (en) * | 2005-01-28 | 2010-07-26 | Euro Celtique Sa | Alcohol resistant dosage forms |
| EP1702558A1 (en) | 2005-02-28 | 2006-09-20 | Euro-Celtique S.A. | Method and device for the assessment of bowel function |
| EP1695700A1 (en) * | 2005-02-28 | 2006-08-30 | Euro-Celtique S.A. | Dosage form containing oxycodone and naloxone |
| EP1813276A1 (en) * | 2006-01-27 | 2007-08-01 | Euro-Celtique S.A. | Tamper resistant dosage forms |
| EP2317991B1 (en) * | 2008-07-07 | 2017-05-03 | Euro-Celtique S.A. | Use of opioid antagonists for treating urinary retention |
| WO2010036977A2 (en) * | 2008-09-25 | 2010-04-01 | New England Medical Center Hospitals, Inc. | Combination therapies with topiramate for seizures, restless legs syndrome, and other neurological conditions |
| SG174286A1 (en) | 2009-03-10 | 2011-10-28 | Euro Celtique Sa | Immediate release pharmaceutical compositions comprising oxycodone and naloxone |
| US8690933B2 (en) * | 2009-08-31 | 2014-04-08 | Brigham Young University | System and method for treating symptoms of restless legs syndrome |
| US8652527B1 (en) | 2013-03-13 | 2014-02-18 | Upsher-Smith Laboratories, Inc | Extended-release topiramate capsules |
| US9101545B2 (en) | 2013-03-15 | 2015-08-11 | Upsher-Smith Laboratories, Inc. | Extended-release topiramate capsules |
| JP2016525138A (ja) | 2013-07-23 | 2016-08-22 | ユーロ−セルティーク エス.エイ. | 疼痛および腸内ディスバイオシスをもたらす疾患および/または腸内細菌移行に対するリスクを高める疾患に罹患している患者における痛みの治療への使用のためのオキシコドンおよびナロキソンの組み合わせ |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BR0008791A (pt) * | 1999-02-17 | 2005-04-05 | Ortho Mcneil Pharm Inc | Derivados anticonvulsivos, úteis no tratamento de tremor essencial |
| WO2000061138A1 (en) * | 1999-04-08 | 2000-10-19 | Ortho-Mcneil Pharmaceutical, Inc. | Anticonvulsant derivatives useful in treating chronic neurodegenerative disorders |
| HUP0203198A3 (en) * | 1999-08-20 | 2005-07-28 | Ortho Mcneil Pharm Inc | Pharmaceutical composition comprising a tramadol material and an anticonvulsant drug, process for its preparation and its use |
| SE0000601D0 (sv) * | 2000-02-24 | 2000-02-24 | Jan Hedner | Sätt att behandla och diagnostisera andningsstörningar i sömnen och medel för att utföra sättet |
-
2002
- 2002-09-23 JP JP2003530311A patent/JP2005512965A/ja not_active Withdrawn
- 2002-09-23 CA CA002461539A patent/CA2461539A1/en not_active Abandoned
- 2002-09-23 MX MXPA04002709A patent/MXPA04002709A/es not_active Application Discontinuation
- 2002-09-23 EP EP02773544A patent/EP1429787A1/en not_active Withdrawn
- 2002-09-23 AU AU2002336765A patent/AU2002336765B2/en not_active Ceased
- 2002-09-23 WO PCT/US2002/030194 patent/WO2003026676A1/en not_active Ceased
- 2002-09-23 NZ NZ531871A patent/NZ531871A/en not_active IP Right Cessation
- 2002-09-23 US US10/252,814 patent/US20030092759A1/en not_active Abandoned
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