JP2023513419A5 - - Google Patents
Info
- Publication number
- JP2023513419A5 JP2023513419A5 JP2022544153A JP2022544153A JP2023513419A5 JP 2023513419 A5 JP2023513419 A5 JP 2023513419A5 JP 2022544153 A JP2022544153 A JP 2022544153A JP 2022544153 A JP2022544153 A JP 2022544153A JP 2023513419 A5 JP2023513419 A5 JP 2023513419A5
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- membered
- ring
- cancer
- independently
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNPCT/CN2020/073786 | 2020-01-22 | ||
| CN2020073786 | 2020-01-22 | ||
| CNPCT/CN2020/076159 | 2020-02-21 | ||
| CN2020076159 | 2020-02-21 | ||
| CNPCT/CN2020/085922 | 2020-04-21 | ||
| CN2020085922 | 2020-04-21 | ||
| PCT/CN2021/073169 WO2021147974A1 (en) | 2020-01-22 | 2021-01-22 | Novel heterocyclic compounds useful as aurora a selective inhibitors |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2023513419A JP2023513419A (ja) | 2023-03-31 |
| JP2023513419A5 true JP2023513419A5 (https=) | 2024-01-25 |
| JP7688646B2 JP7688646B2 (ja) | 2025-06-04 |
Family
ID=76993163
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022544153A Active JP7688646B2 (ja) | 2020-01-22 | 2021-01-22 | オーロラａ選択的阻害剤として有用な新規複素環式化合物 |
Country Status (13)
| Country | Link |
|---|---|
| US (2) | US20230128198A1 (https=) |
| EP (1) | EP4093736A4 (https=) |
| JP (1) | JP7688646B2 (https=) |
| KR (1) | KR102828343B1 (https=) |
| CN (2) | CN114423751B (https=) |
| AU (1) | AU2021209744B2 (https=) |
| CL (1) | CL2022001951A1 (https=) |
| CO (1) | CO2022010878A2 (https=) |
| IL (1) | IL294247B2 (https=) |
| MX (1) | MX2022009059A (https=) |
| PH (1) | PH12022551858A1 (https=) |
| TW (1) | TWI785474B (https=) |
| WO (1) | WO2021147974A1 (https=) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3823974A1 (en) | 2018-07-20 | 2021-05-26 | F. Hoffmann-La Roche AG | Sulfonimidamide compounds as inhibitors of interleukin-1 activity |
| CN112239465A (zh) | 2019-07-16 | 2021-01-19 | 微境生物医药科技(上海)有限公司 | 极光激酶抑制剂及其用途 |
| CN112898292A (zh) | 2019-12-03 | 2021-06-04 | 微境生物医药科技(上海)有限公司 | 新型极光激酶抑制剂及其用途 |
| JP2025506772A (ja) * | 2022-02-23 | 2025-03-13 | リペア セラピューティクス インコーポレイテッド | ポロ様キナーゼ４（ｐｌｋ４）阻害剤、医薬組成物、ならびにそれらを調製する方法、及びそれらの使用方法 |
| CN115057811B (zh) * | 2022-05-26 | 2024-06-14 | 安庆朗坤药业有限公司 | 一种2-溴甲基-3,5-二氟吡啶的制备方法 |
| CN115322143B (zh) * | 2022-07-21 | 2023-07-14 | 安徽德诺医药股份有限公司 | 一种4-哌啶甲酸叔丁酯盐酸盐的制备方法 |
| WO2024230647A1 (zh) * | 2023-05-05 | 2024-11-14 | 苏州信诺维医药科技股份有限公司 | 杂环类化合物、其药物组合物和其应用 |
| CN116903587B (zh) * | 2023-06-01 | 2024-03-22 | 三峡大学 | 一种角鲨烯环氧酶抑制剂及其用途 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2008081492A (ja) * | 2006-08-31 | 2008-04-10 | Banyu Pharmaceut Co Ltd | オーロラａ選択的阻害作用を有する新規アミノピリジン誘導体 |
| EP2254888B1 (en) * | 2008-02-22 | 2014-12-24 | Msd K.K. | Novel aminopyridine derivatives having aurora a selective inhibitory action |
| TWI485146B (zh) * | 2012-02-29 | 2015-05-21 | Taiho Pharmaceutical Co Ltd | Novel piperidine compounds or salts thereof |
| TWI693218B (zh) * | 2014-11-14 | 2020-05-11 | 美商美國禮來大藥廠 | 極光ａ激酶抑制劑 |
| MX2021006011A (es) * | 2018-11-30 | 2021-09-21 | Lilly Co Eli | Un inhibidor de la quinasa aurora a para su uso en el tratamiento del neuroblastoma. |
| CN112239465A (zh) * | 2019-07-16 | 2021-01-19 | 微境生物医药科技(上海)有限公司 | 极光激酶抑制剂及其用途 |
| CN112898292A (zh) * | 2019-12-03 | 2021-06-04 | 微境生物医药科技(上海)有限公司 | 新型极光激酶抑制剂及其用途 |
-
2021
- 2021-01-21 TW TW110102296A patent/TWI785474B/zh active
- 2021-01-22 WO PCT/CN2021/073169 patent/WO2021147974A1/en not_active Ceased
- 2021-01-22 MX MX2022009059A patent/MX2022009059A/es unknown
- 2021-01-22 CN CN202180003823.8A patent/CN114423751B/zh active Active
- 2021-01-22 CN CN202310353468.8A patent/CN116354936A/zh active Pending
- 2021-01-22 JP JP2022544153A patent/JP7688646B2/ja active Active
- 2021-01-22 AU AU2021209744A patent/AU2021209744B2/en active Active
- 2021-01-22 PH PH1/2022/551858A patent/PH12022551858A1/en unknown
- 2021-01-22 IL IL294247A patent/IL294247B2/en unknown
- 2021-01-22 US US17/794,641 patent/US20230128198A1/en not_active Abandoned
- 2021-01-22 KR KR1020227021336A patent/KR102828343B1/ko active Active
- 2021-01-22 EP EP21743926.4A patent/EP4093736A4/en active Pending
- 2021-09-24 US US17/484,456 patent/US11384066B1/en active Active
-
2022
- 2022-07-19 CL CL2022001951A patent/CL2022001951A1/es unknown
- 2022-08-02 CO CONC2022/0010878A patent/CO2022010878A2/es unknown
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2023513419A5 (https=) | ||
| KR100256853B1 (ko) | 혈관 내막과 형성 증진을 억제하기위한 약제학적 조성물 | |
| JP2001526269A5 (https=) | ||
| JP2008523099A5 (https=) | ||
| JP2001525359A5 (https=) | ||
| JP2001247459A (ja) | 癌の組み合わせ療法 | |
| CA2440037A1 (en) | Benzimidazole derivatives for modulating the rage receptor | |
| CA2708149A1 (en) | Combinations of therapeutic agents for treating cancer | |
| EP0527494B1 (en) | Compositon containing rhodacyanine dyes for treating cancer | |
| CA2946890A1 (en) | Naphthofuran compounds and compositions for targeting cancer stem cells | |
| JP2005507938A5 (https=) | ||
| JP2008500366A5 (https=) | ||
| CN102821605B (zh) | 改进的稳定的（e）-4-羧基苯乙烯基-4-氯苄基砜水性制剂 | |
| WO2003074053A1 (en) | Use of epothilones in the treatment of brain diseases associated with proliferative processes | |
| RU2004122427A (ru) | Пирролидин-2-оны в качестве ингибиторов фактора ха | |
| JP2002505276A (ja) | 潰瘍用医薬組成物 | |
| WO1999018099B1 (en) | Aryl thiophene derivatives as pde iv inhibitors | |
| NZ541187A (en) | Use of a combination containing a non-nucleoside reverse transcriptase inhibitor (NNRTI) with an inhibitor of cytochrome P450, such as protease inhibitors | |
| JP4610481B2 (ja) | 抗腫瘍効果増強剤及び抗腫瘍剤 | |
| RU2208013C2 (ru) | ПРОИЗВОДНЫЕ 8-ЗАМЕЩЕННОГО-9H-1,3-ДИОКСОЛ/4,5-h//2,3/БЕНЗОДИАЗЕПИНА, ЯВЛЯЮЩИЕСЯ ИНГИБИТОРАМИ AMPA/КАИНАТНОГО РЕЦЕПТОРА, СПОСОБ ИХ ПОЛУЧЕНИЯ, ФАРМАЦЕВТИЧЕСКАЯ КОМПОЗИЦИЯ НА ИХ ОСНОВЕ И СПОСОБ ЛЕЧЕНИЯ | |
| Barbhaiya et al. | Clinical pharmacological studies of amoxycillin: effect of probenecid. | |
| JP2006523233A5 (https=) | ||
| JP2002518506A5 (https=) | ||
| RU2007104176A (ru) | Синтез и применение (-)-бета-элемена, (-)-бета-элеменала, (-)-бета-элеменола, фторида (-)-бета-элемена и их аналогов, а также промежуточных продуктов и композитов | |
| US5618831A (en) | Composition and method for treating cancer |