JP2004532289A5 - - Google Patents

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Publication number
JP2004532289A5
JP2004532289A5 JP2002565549A JP2002565549A JP2004532289A5 JP 2004532289 A5 JP2004532289 A5 JP 2004532289A5 JP 2002565549 A JP2002565549 A JP 2002565549A JP 2002565549 A JP2002565549 A JP 2002565549A JP 2004532289 A5 JP2004532289 A5 JP 2004532289A5
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JP
Japan
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group
independently
substituted
compound
alkyl
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2002565549A
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English (en)
Japanese (ja)
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JP2004532289A (ja
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Publication date
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Priority claimed from PCT/US2002/004781 external-priority patent/WO2002065988A2/en
Publication of JP2004532289A publication Critical patent/JP2004532289A/ja
Publication of JP2004532289A5 publication Critical patent/JP2004532289A5/ja
Pending legal-status Critical Current

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JP2002565549A 2001-02-20 2002-02-19 末端分枝高分子リンカーおよびそれを含む高分子複合体 Pending JP2004532289A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US27000901P 2001-02-20 2001-02-20
PCT/US2002/004781 WO2002065988A2 (en) 2001-02-20 2002-02-19 Terminally-branched polymeric linkers and polymeric conjugates containing the same

Publications (2)

Publication Number Publication Date
JP2004532289A JP2004532289A (ja) 2004-10-21
JP2004532289A5 true JP2004532289A5 (https=) 2005-12-22

Family

ID=23029515

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2002565549A Pending JP2004532289A (ja) 2001-02-20 2002-02-19 末端分枝高分子リンカーおよびそれを含む高分子複合体

Country Status (10)

Country Link
US (1) US20020183259A1 (https=)
EP (1) EP1362053B1 (https=)
JP (1) JP2004532289A (https=)
AT (1) ATE378342T1 (https=)
AU (1) AU2002251988A1 (https=)
CA (1) CA2437989A1 (https=)
DE (1) DE60223499T2 (https=)
DK (1) DK1362053T3 (https=)
MX (1) MXPA03007392A (https=)
WO (1) WO2002065988A2 (https=)

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US8334364B2 (en) 2006-11-06 2012-12-18 Nipon Kayaku Kabushiki Kaisha High-molecular weight derivative of nucleic acid antimetabolite
JP5548365B2 (ja) * 2006-11-08 2014-07-16 日本化薬株式会社 核酸系代謝拮抗剤の高分子誘導体
EP2118127A4 (en) 2007-01-31 2010-12-01 Affymax Inc NICKET-BASED LINKER FOR BONDING MODIFYING GROUPS OF POLYPEPTIDES AND OTHER MACROMOLECULES
JP5349318B2 (ja) 2007-09-28 2013-11-20 日本化薬株式会社 ステロイド類の高分子結合体
CN101977631A (zh) * 2008-03-18 2011-02-16 日本化药株式会社 生理活性物质的高分子量偶联物
JP5366940B2 (ja) 2008-05-08 2013-12-11 日本化薬株式会社 葉酸若しくは葉酸誘導体の高分子結合体
JP5544357B2 (ja) 2009-05-15 2014-07-09 日本化薬株式会社 水酸基を有する生理活性物質の高分子結合体
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KR20140024833A (ko) 2010-11-17 2014-03-03 니폰 가야꾸 가부시끼가이샤 신규한 시티딘계 대사길항제의 고분자 유도체
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CN103874722B (zh) 2011-09-11 2016-06-29 日本化药株式会社 嵌段共聚物的制造方法
EP3820879B1 (en) 2018-06-29 2024-11-06 Changchun Changcheng Pharmaceutical Technology Co., LTD Phosphorus-containing prodrugs of gemcitabine

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