JP2004532289A5 - - Google Patents

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Publication number
JP2004532289A5
JP2004532289A5 JP2002565549A JP2002565549A JP2004532289A5 JP 2004532289 A5 JP2004532289 A5 JP 2004532289A5 JP 2002565549 A JP2002565549 A JP 2002565549A JP 2002565549 A JP2002565549 A JP 2002565549A JP 2004532289 A5 JP2004532289 A5 JP 2004532289A5
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JP
Japan
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group
independently
substituted
compound
alkyl
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
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JP2002565549A
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English (en)
Japanese (ja)
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JP2004532289A (ja
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Publication date
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Priority claimed from PCT/US2002/004781 external-priority patent/WO2002065988A2/en
Publication of JP2004532289A publication Critical patent/JP2004532289A/ja
Publication of JP2004532289A5 publication Critical patent/JP2004532289A5/ja
Pending legal-status Critical Current

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JP2002565549A 2001-02-20 2002-02-19 末端分枝高分子リンカーおよびそれを含む高分子複合体 Pending JP2004532289A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US27000901P 2001-02-20 2001-02-20
PCT/US2002/004781 WO2002065988A2 (en) 2001-02-20 2002-02-19 Terminally-branched polymeric linkers and polymeric conjugates containing the same

Publications (2)

Publication Number Publication Date
JP2004532289A JP2004532289A (ja) 2004-10-21
JP2004532289A5 true JP2004532289A5 (https=) 2005-12-22

Family

ID=23029515

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2002565549A Pending JP2004532289A (ja) 2001-02-20 2002-02-19 末端分枝高分子リンカーおよびそれを含む高分子複合体

Country Status (10)

Country Link
US (1) US20020183259A1 (https=)
EP (1) EP1362053B1 (https=)
JP (1) JP2004532289A (https=)
AT (1) ATE378342T1 (https=)
AU (1) AU2002251988A1 (https=)
CA (1) CA2437989A1 (https=)
DE (1) DE60223499T2 (https=)
DK (1) DK1362053T3 (https=)
MX (1) MXPA03007392A (https=)
WO (1) WO2002065988A2 (https=)

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WO2008056596A1 (fr) 2006-11-06 2008-05-15 Nippon Kayaku Kabushiki Kaisha Dérivé polymère d'un antagoniste métabolique d'acide nucléique
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US8106154B2 (en) 2007-01-31 2012-01-31 Affymax, Inc. Nitrogen-based linkers for attaching modifying groups to polypeptides and other macromolecules
US8703878B2 (en) 2007-09-28 2014-04-22 Nippon Kayaku Kabushiki Kaisha High-molecular weight conjugate of steroids
WO2009116509A1 (ja) 2008-03-18 2009-09-24 日本化薬株式会社 生理活性物質の高分子結合体
WO2009136572A1 (ja) 2008-05-08 2009-11-12 日本化薬株式会社 葉酸若しくは葉酸誘導体の高分子結合体
EP2431403B1 (en) 2009-05-15 2016-09-28 Nipponkayaku Kabushikikaisha Polymer conjugate of bioactive substance having hydroxy group
AU2011307608B8 (en) 2010-09-30 2015-08-27 Grünenthal GmbH Crystalline naloxol-PEG conjugate
EP2641605B1 (en) 2010-11-17 2018-03-07 Nippon Kayaku Kabushiki Kaisha Polymer derivative of cytidine metabolism antagonist
AU2012296950B2 (en) * 2011-08-12 2016-09-22 Ascendis Pharma A/S Polymeric hyperbranched carrier-linked prodrugs
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