JP2005528380A5 - - Google Patents

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Publication number
JP2005528380A5
JP2005528380A5 JP2003582125A JP2003582125A JP2005528380A5 JP 2005528380 A5 JP2005528380 A5 JP 2005528380A5 JP 2003582125 A JP2003582125 A JP 2003582125A JP 2003582125 A JP2003582125 A JP 2003582125A JP 2005528380 A5 JP2005528380 A5 JP 2005528380A5
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JP
Japan
Prior art keywords
substituted
alkyl
group
compound
heteroalkyl
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Application number
JP2003582125A
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English (en)
Japanese (ja)
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JP4527404B2 (ja
JP2005528380A (ja
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Publication date
Application filed filed Critical
Priority claimed from PCT/US2003/009875 external-priority patent/WO2003084926A2/en
Publication of JP2005528380A publication Critical patent/JP2005528380A/ja
Publication of JP2005528380A5 publication Critical patent/JP2005528380A5/ja
Application granted granted Critical
Publication of JP4527404B2 publication Critical patent/JP4527404B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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JP2003582125A 2002-04-04 2003-03-31 インドールのポリマー性アシル誘導体 Expired - Fee Related JP4527404B2 (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US36973202P 2002-04-04 2002-04-04
PCT/US2003/009875 WO2003084926A2 (en) 2002-04-04 2003-03-31 Polymeric acyl derivatives of indoles

Publications (3)

Publication Number Publication Date
JP2005528380A JP2005528380A (ja) 2005-09-22
JP2005528380A5 true JP2005528380A5 (https=) 2006-03-02
JP4527404B2 JP4527404B2 (ja) 2010-08-18

Family

ID=28791989

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2003582125A Expired - Fee Related JP4527404B2 (ja) 2002-04-04 2003-03-31 インドールのポリマー性アシル誘導体

Country Status (6)

Country Link
US (1) US7393953B2 (https=)
EP (1) EP1494757A2 (https=)
JP (1) JP4527404B2 (https=)
AU (1) AU2003226166A1 (https=)
CA (1) CA2479810A1 (https=)
WO (1) WO2003084926A2 (https=)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1757607A1 (en) 2005-08-24 2007-02-28 Molisa GmbH N5-substituted benzo¬2,3|azepino¬4,5-b|indol-6-ones for treating tropical diseases
JP2010521465A (ja) * 2007-03-12 2010-06-24 ネクター セラピューティックス 複合体のデノボ合成
WO2008112287A1 (en) * 2007-03-12 2008-09-18 Nektar Therapeutics Oligomer-beta blocker conjugates
US8748648B2 (en) 2007-09-06 2014-06-10 Nektar Therapeutics Oligomer-calcium channel blocker conjugates
AU2010277559B2 (en) 2009-07-31 2016-08-11 Sanofi-Aventis Deutschland Gmbh Prodrugs comprising an insulin linker conjugate
PL2459171T3 (pl) 2009-07-31 2017-11-30 Sanofi-Aventis Deutschland Gmbh Kompozycja insuliny o długim działaniu
CN102573913B (zh) 2009-07-31 2014-06-18 阿森迪斯药物股份有限公司 可生物降解的基于聚乙二醇的水不溶性水凝胶
CN102724967A (zh) * 2009-12-31 2012-10-10 安龙制药公司 包括可释放的脲连接体的含芳香胺化合物的聚合缀合物
EP2438930A1 (en) 2010-09-17 2012-04-11 Sanofi-Aventis Deutschland GmbH Prodrugs comprising an exendin linker conjugate
AU2012296950B2 (en) 2011-08-12 2016-09-22 Ascendis Pharma A/S Polymeric hyperbranched carrier-linked prodrugs
WO2013024047A1 (en) 2011-08-12 2013-02-21 Ascendis Pharma A/S High-loading water-soluble carrier-linked prodrugs
AU2012296951B2 (en) 2011-08-12 2016-09-15 Ascendis Pharma A/S Protein carrier-linked prodrugs
US20150010634A1 (en) 2011-10-12 2015-01-08 Ascendis Pharma Ophthamology Division A/S Prevention and treatment of ocular conditions
CA2885169C (en) 2012-10-11 2021-06-22 Ascendis Pharma A/S Diagnosis, prevention and treatment of diseases of the joint

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5840900A (en) * 1993-10-20 1998-11-24 Enzon, Inc. High molecular weight polymer-based prodrugs
DE19636889A1 (de) * 1996-09-11 1998-03-12 Felix Dr Kratz Antineoplastisch wirkende Transferrin- und Albuminkonjugate zytostatischer Verbindungen aus der Gruppe der Anthrazykline, Alkylantien, Antimetabolite und Cisplatin-Analoga und diese enthaltende Arzneimittel
US6251382B1 (en) * 1998-04-17 2001-06-26 Enzon, Inc. Biodegradable high molecular weight polymeric linkers and their conjugates
US6153655A (en) * 1998-04-17 2000-11-28 Enzon, Inc. Terminally-branched polymeric linkers and polymeric conjugates containing the same
WO1999065910A1 (en) 1998-06-16 1999-12-23 The Government Of The United States Of America, Represented By The Secretary, Department Of Health And Human Services Fused azepinone cyclin dependent kinase inhibitors
FR2804959B1 (fr) * 2000-02-15 2006-04-28 Centre Nat Rech Scient Utilisation de derives de paullones pour la fabrication de medicaments

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