JP2004530703A5 - - Google Patents
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- Publication number
- JP2004530703A5 JP2004530703A5 JP2002591516A JP2002591516A JP2004530703A5 JP 2004530703 A5 JP2004530703 A5 JP 2004530703A5 JP 2002591516 A JP2002591516 A JP 2002591516A JP 2002591516 A JP2002591516 A JP 2002591516A JP 2004530703 A5 JP2004530703 A5 JP 2004530703A5
- Authority
- JP
- Japan
- Prior art keywords
- azithromycin
- crystalline form
- ppm
- solid state
- nmr spectrum
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- MQTOSJVFKKJCRP-BICOPXKESA-N azithromycin Chemical compound O([C@@H]1[C@@H](C)C(=O)O[C@@H]([C@@]([C@H](O)[C@@H](C)N(C)C[C@H](C)C[C@@](C)(O)[C@H](O[C@H]2[C@@H]([C@H](C[C@@H](C)O2)N(C)C)O)[C@H]1C)(C)O)CC)[C@H]1C[C@@](C)(OC)[C@@H](O)[C@H](C)O1 MQTOSJVFKKJCRP-BICOPXKESA-N 0.000 claims 19
- 229960004099 azithromycin Drugs 0.000 claims 19
- 238000004922 13C solid-state nuclear magnetic resonance spectroscopy Methods 0.000 claims 6
- 238000001228 spectrum Methods 0.000 claims 6
- 239000000126 substance Substances 0.000 claims 6
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US29256501P | 2001-05-22 | 2001-05-22 | |
| US29774101P | 2001-06-12 | 2001-06-12 | |
| US34304101P | 2001-12-21 | 2001-12-21 | |
| PCT/IB2002/001570 WO2002094843A1 (en) | 2001-05-22 | 2002-05-01 | Crystal forms of azithromycin |
Related Child Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006061758A Division JP4584162B2 (ja) | 2001-05-22 | 2006-03-07 | 結晶形アジスロマイシン |
| JP2007030654A Division JP2007161726A (ja) | 2001-05-22 | 2007-02-09 | 結晶形アジスロマイシン |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2004530703A JP2004530703A (ja) | 2004-10-07 |
| JP2004530703A5 true JP2004530703A5 (cg-RX-API-DMAC7.html) | 2006-04-27 |
Family
ID=27404135
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2002591516A Withdrawn JP2004530703A (ja) | 2001-05-22 | 2002-05-01 | 結晶形アジスロマイシン |
| JP2006061758A Expired - Fee Related JP4584162B2 (ja) | 2001-05-22 | 2006-03-07 | 結晶形アジスロマイシン |
| JP2007030654A Pending JP2007161726A (ja) | 2001-05-22 | 2007-02-09 | 結晶形アジスロマイシン |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006061758A Expired - Fee Related JP4584162B2 (ja) | 2001-05-22 | 2006-03-07 | 結晶形アジスロマイシン |
| JP2007030654A Pending JP2007161726A (ja) | 2001-05-22 | 2007-02-09 | 結晶形アジスロマイシン |
Country Status (35)
Families Citing this family (53)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HRP20020231A2 (en) | 2002-03-18 | 2003-12-31 | Pliva D D | ISOSTRUCTURAL PSEUDOPOLYMORPHS OF 9-DEOXO-9a-AZA-9a-METHYL-9a-HOMOERYTHROMYCIN A |
| KR100603226B1 (ko) * | 1998-11-30 | 2006-08-28 | 테바 파마슈티컬 인더스트리즈 리미티드 | 아지스로마이신의 에탄올레이트, 이의 제조 방법 및 약학 조성물 |
| EP1313749B1 (en) * | 2000-08-23 | 2005-10-12 | Wockhardt Limited | Process for preparation of anhydrous azithromycin |
| KR100431431B1 (ko) * | 2001-04-25 | 2004-05-14 | 한미약품 주식회사 | 아지트로마이신 수화물의 1,2-프로필렌글리콜 내포화합물,그의 제조방법 및 그의 약학적 조성물 |
| KR100574153B1 (ko) * | 2001-05-22 | 2006-04-25 | 화이자 프로덕츠 인코포레이티드 | 아지트로마이신의 결정형 |
| ITMI20011762A1 (it) | 2001-08-10 | 2003-02-10 | Cosmo Spa | Esteri di 17alfa,21-diidrossipregnene, loro uso come agenti anti-androgenetici e procedimenti per la loro preparazione |
| BR0215175A (pt) * | 2001-12-21 | 2004-12-28 | Pfizer Prod Inc | Métodos para a granulação úmida de azitromicina |
| JP2005513099A (ja) * | 2001-12-21 | 2005-05-12 | ファイザー・プロダクツ・インク | アジスロマイシンの直接的に圧縮可能な配合品 |
| WO2003063838A1 (en) | 2002-02-01 | 2003-08-07 | Pfizer Products Inc. | Dry granulated formulations of azithromycin |
| HRP20020614A2 (en) | 2002-07-22 | 2004-06-30 | PLIVA-ISTRAŽIVAČKI INSTITUT d.o.o. | Rhombic pseudopolymorph of 9-deoxo-9a-aza-9a-methyl-9a-homoerythromycin a |
| CA2422972A1 (en) * | 2003-03-21 | 2004-09-21 | Apotex Inc. | Isopropanolate of azithromycin and method of manufacturing |
| US20050013835A1 (en) * | 2003-07-15 | 2005-01-20 | Pfizer Inc. | Stable non-dihydrate azithromycin oral suspensions |
| ATE421882T1 (de) | 2003-07-24 | 2009-02-15 | Pliva Hrvatska D O O | Schnellösliches azithromycin in einzeldosisform |
| EP1878432A1 (en) * | 2003-07-24 | 2008-01-16 | Pliva - Research and Development Ltd. | Single dose fast dissolving azithromycin |
| ES2755334T3 (es) * | 2003-11-17 | 2020-04-22 | Merck & Cie | Proceso para la preparación de formas cristalinas B de clorhidrato de (6R)-L-eritro-tetrahidrobiopterina a partir de otras formas cristalinas |
| US7943585B2 (en) | 2003-12-22 | 2011-05-17 | Sandoz, Inc. | Extended release antibiotic composition |
| US7468428B2 (en) | 2004-03-17 | 2008-12-23 | App Pharmaceuticals, Llc | Lyophilized azithromycin formulation |
| US20060116336A1 (en) * | 2004-03-17 | 2006-06-01 | American Pharmaceutical Partners, Inc. | Lyophilized azithromycin formulation |
| US20050250714A1 (en) * | 2004-05-06 | 2005-11-10 | Lin Kangwen L | Crystalline forms of 9-(S)-erythromycylamine |
| WO2005118586A1 (en) * | 2004-06-02 | 2005-12-15 | Sandoz Ag | Meropenem intermediate in crystalline form |
| US7683162B2 (en) | 2004-08-30 | 2010-03-23 | Taro Pharmaceutical Industries Limited | Process of preparing a crystalline azithromycin monohydrate |
| US8495244B2 (en) * | 2005-06-29 | 2013-07-23 | Jumpstart Wireless Corporation | System and method for dynamic automatic communication path selection, distributed device synchronization and task delegation |
| EP1910393A2 (en) * | 2005-07-05 | 2008-04-16 | Hetero Drugs Limited | A novel process for the preparation of didanosine using novel intermediates |
| WO2007007148A1 (en) * | 2005-07-14 | 2007-01-18 | Pfizer Products Inc. | Process for forming amorphous azithromycin particles |
| NZ566073A (en) * | 2005-09-21 | 2011-08-26 | 4Sc Ag | Sulphonylpyrrole hydrochloride salts as histone deacetylases inhibitors |
| KR20080067365A (ko) * | 2005-10-31 | 2008-07-18 | 얀센 파마슈티카 엔.브이. | 피페라지닐 및 디아자파닐 벤즈아미드 유도체의 신규한제조 방법 |
| US8558765B2 (en) * | 2005-11-07 | 2013-10-15 | Global Oled Technology Llc | Method and apparatus for uniformity and brightness correction in an electroluminescent display |
| EA016054B1 (ru) * | 2006-06-16 | 2012-01-30 | Х. Лундбекк А/С | Кристаллические формы 4-[2-(4-метилфенилсульфанил)фенил] пиперидина с объединенным ингибированием повторного поглощения серотонина и норадреналина для лечения невропатической боли |
| US7919598B2 (en) * | 2006-06-28 | 2011-04-05 | Bristol-Myers Squibb Company | Crystal structures of SGLT2 inhibitors and processes for preparing same |
| KR20150028857A (ko) * | 2006-10-27 | 2015-03-16 | 시그날 파마소티칼 엘엘씨 | 4-[9-(테트라하이드로-퓨란-3-일)-8-(2,4,6-트리플루오로-페닐아미노)-9ｈ-퓨린-2-일아미노]-사이클로헥산-1-올을포함하는 고체 형태들, 이들의 조성물들 및 이들의 용도 |
| CA2570949A1 (en) * | 2006-12-12 | 2008-06-12 | Apotex Pharmachem Inc. | Ibandronate sodium propylene glycol solvate and processes for the preparation thereof |
| US7834195B2 (en) | 2007-01-24 | 2010-11-16 | Apotex Pharmachem Inc. | Atorvastatin calcium propylene glycol solvates |
| US7919676B2 (en) | 2007-08-03 | 2011-04-05 | Pioneer Hi-Bred International, Inc. | Msca1 nucleotide sequences impacting plant male fertility and method of using same |
| ITMI20071616A1 (it) | 2007-08-03 | 2009-02-04 | Cosmo Spa | Processo enzimatico per l'ottenimento di 17-alfa monoesteri del cortexolone e/o suoi 9,11-deidroderivati. |
| EP2085397A1 (en) * | 2008-01-21 | 2009-08-05 | Esteve Quimica, S.A. | Crystalline form of abacavir |
| US7935817B2 (en) * | 2008-03-31 | 2011-05-03 | Apotex Pharmachem Inc. | Salt form and cocrystals of adefovir dipivoxil and processes for preparation thereof |
| AR071318A1 (es) * | 2008-04-15 | 2010-06-09 | Basilea Pharmaceutica Ag | Benzhidril ester del acido (6r,7r)-7-{2-(5-amino-[1,2,4]tiadiazol-3-il)-2-[(z)-tritiloxiimino]-acetilamino}-3-[(r)-1'-terc-butoxicarbonil-2-oxo-[1,3']bipirrolidinil-(3e)-ilidenometil]-8-oxo-5-tia-1-aza-biciclo[4.2.0]oct-2-eno-2-carboxilico cristalino; su elaboracion y uso |
| US8097719B2 (en) * | 2008-07-15 | 2012-01-17 | Genesen Labs | Meropenem intermediate in novel crystalline form and a method of manufacture of meropenem |
| US8216363B2 (en) * | 2008-10-27 | 2012-07-10 | Illinois Institute Of Technology | Continuous antisolvent crystallization process and system using plug flow reactors |
| US20100158821A1 (en) * | 2008-12-22 | 2010-06-24 | Eastman Chemical Company | Antimicrobial agents, compositions and products containing the same, and methods of using the compositions and products |
| BRPI1009823A2 (pt) | 2009-03-13 | 2019-09-24 | Da Volterra Assistance Publique Hopitaux De Paris E Univ Paris Diderot Paris 7 | "composição compreendendo um sistema de dispensação de droga, conjunto de uma primeira e uma segunda composição, e, kit." |
| US8106111B2 (en) | 2009-05-15 | 2012-01-31 | Eastman Chemical Company | Antimicrobial effect of cycloaliphatic diol antimicrobial agents in coating compositions |
| WO2011112828A1 (en) | 2010-03-12 | 2011-09-15 | Omeros Corporation | Pde10 inhibitors and related compositions and methods |
| CA2808904A1 (en) * | 2010-09-01 | 2012-03-08 | Arena Pharmaceuticals, Inc. | Non-hygroscopic salts of 5-ht2c agonists |
| CN103930419B (zh) * | 2011-09-30 | 2016-06-01 | 广东东阳光药业有限公司 | 阿齐沙坦的晶型及其制备方法 |
| WO2013088274A1 (en) | 2011-12-14 | 2013-06-20 | Wockhardt Limited | Anhydrous amorphous azithromycin composition free of azithromycin dihydrate |
| NZ716494A (en) | 2014-04-28 | 2017-07-28 | Omeros Corp | Processes and intermediates for the preparation of a pde10 inhibitor |
| NZ630803A (en) | 2014-04-28 | 2016-03-31 | Omeros Corp | Optically active pde10 inhibitor |
| BR112017022936A2 (pt) | 2015-04-24 | 2018-07-17 | Omeros Corp | inibidores da pde10 e composições e métodos relacionados |
| EP3108879A1 (en) | 2015-06-25 | 2016-12-28 | Cassiopea S.p.A. | High concentration formulation |
| WO2017079678A1 (en) | 2015-11-04 | 2017-05-11 | Omeros Corporation | Solid state forms of a pde10 inhibitor |
| KR102691700B1 (ko) * | 2017-09-07 | 2024-08-02 | 아테넥스 에이치케이 이노베이티브 리미티드 | 2-(5-(4-(2-모르폴리노에톡시)페닐)피리딘-2-일)-n-벤질아세트아미드의 고체 형태 |
| CN111303230B (zh) * | 2020-03-09 | 2021-07-13 | 中国食品药品检定研究院 | 一种黄体酮共晶物及其制备方法和用途 |
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| SI7910768A8 (en) | 1979-04-02 | 1996-06-30 | Pliva Pharm & Chem Works | Process for pripering 11-aza-4-0-cladinosyl-6-0-desosaminyl-15-ethyl- 7,13,14-trihydroxy-3,5,7,9,12,14-hexamethyl- oxacyclopentadecane-2-one and their derivatives |
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| KR100603226B1 (ko) * | 1998-11-30 | 2006-08-28 | 테바 파마슈티컬 인더스트리즈 리미티드 | 아지스로마이신의 에탄올레이트, 이의 제조 방법 및 약학 조성물 |
| EP1189915B1 (en) * | 1999-06-29 | 2006-07-26 | Sandoz Ag | Process for the production of azithromycin |
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| WO2002010144A1 (es) | 2000-07-25 | 2002-02-07 | Laboratorio Silanes, S.A. De C.V. | PROCESO PARA LA PREPARACION EN UN SOLO PASO DE 7,16-DIOXA-2-AZA-10-O-CLADINOSIL-12-O-DESOSAMINIL-4,5-DIHIDROXI-6-ETIL-3,5,9,11,13,15-HEXAMETILBICICLO[11.2.1]HEXADECA-1(2)-EN-8-ONA Y OBTENCION DE UNA FORMA NUEVA DE 9-DESOXO-9a-AZA-9a-METIL-9a-HOMOERITROMICINA A |
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| EP1313749B1 (en) | 2000-08-23 | 2005-10-12 | Wockhardt Limited | Process for preparation of anhydrous azithromycin |
| JP2004519430A (ja) | 2000-11-27 | 2004-07-02 | バイオケミ・エセ・ア | マクロライドの溶媒和物 |
| IN190080B (cg-RX-API-DMAC7.html) | 2001-01-29 | 2003-06-07 | Alembic Ltd | |
| KR100431431B1 (ko) | 2001-04-25 | 2004-05-14 | 한미약품 주식회사 | 아지트로마이신 수화물의 1,2-프로필렌글리콜 내포화합물,그의 제조방법 및 그의 약학적 조성물 |
| US6861413B2 (en) * | 2001-05-22 | 2005-03-01 | Pfizer Inc. | Stable non-dihydrate azithromycin oral suspensions |
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-
2002
- 2002-05-01 KR KR1020037015125A patent/KR100574153B1/ko not_active Expired - Fee Related
- 2002-05-01 EA EA200301115A patent/EA007618B1/ru not_active IP Right Cessation
- 2002-05-01 ES ES06110765T patent/ES2310886T3/es not_active Expired - Lifetime
- 2002-05-01 BR BR0209918-7A patent/BR0209918A/pt not_active IP Right Cessation
- 2002-05-01 NZ NZ539801A patent/NZ539801A/en unknown
- 2002-05-01 PT PT02726369T patent/PT1390377E/pt unknown
- 2002-05-01 NZ NZ529118A patent/NZ529118A/en unknown
- 2002-05-01 DK DK02726369T patent/DK1390377T3/da active
- 2002-05-01 HU HU0400446A patent/HUP0400446A2/hu unknown
- 2002-05-01 AU AU2002256846A patent/AU2002256846B2/en not_active Ceased
- 2002-05-01 GE GEAP20027185A patent/GEP20084399B/en unknown
- 2002-05-01 AT AT06110765T patent/ATE404575T1/de not_active IP Right Cessation
- 2002-05-01 WO PCT/IB2002/001570 patent/WO2002094843A1/en not_active Ceased
- 2002-05-01 MX MXPA03010028A patent/MXPA03010028A/es active IP Right Grant
- 2002-05-01 AP APAP/P/2003/002906A patent/AP2003002906A0/en unknown
- 2002-05-01 CZ CZ20033154A patent/CZ20033154A3/cs unknown
- 2002-05-01 YU YU91603A patent/YU91603A/sh unknown
- 2002-05-01 PL PL02367091A patent/PL367091A1/xx not_active Application Discontinuation
- 2002-05-01 EE EEP200300575A patent/EE200300575A/xx unknown
- 2002-05-01 ES ES02726369T patent/ES2258142T3/es not_active Expired - Lifetime
- 2002-05-01 DE DE60209704T patent/DE60209704T2/de not_active Revoked
- 2002-05-01 IL IL15859102A patent/IL158591A0/xx unknown
- 2002-05-01 EP EP02726369A patent/EP1390377B1/en not_active Revoked
- 2002-05-01 DE DE60228345T patent/DE60228345D1/de not_active Expired - Lifetime
- 2002-05-01 JP JP2002591516A patent/JP2004530703A/ja not_active Withdrawn
- 2002-05-01 CA CA002391659A patent/CA2391659C/en not_active Expired - Fee Related
- 2002-05-01 SK SK1440-2003A patent/SK14402003A3/sk unknown
- 2002-05-01 EA EA200500630A patent/EA009611B1/ru not_active IP Right Cessation
- 2002-05-01 AT AT02726369T patent/ATE319730T1/de not_active IP Right Cessation
- 2002-05-21 AR ARP020101875A patent/AR036022A1/es unknown
- 2002-05-21 US US10/152,106 patent/US6977243B2/en not_active Expired - Fee Related
- 2002-05-21 MY MYPI20021870A patent/MY129319A/en unknown
- 2002-05-21 PE PE2002000431A patent/PE20021064A1/es not_active Application Discontinuation
- 2002-05-22 PA PA20028545701A patent/PA8545701A1/es unknown
-
2003
- 2003-07-08 TN TNPCT/IB2002/001570A patent/TNSN03121A1/fr unknown
- 2003-08-27 US US10/650,252 patent/US7307156B2/en not_active Expired - Fee Related
- 2003-08-27 US US10/650,253 patent/US7282486B2/en not_active Expired - Fee Related
- 2003-08-27 US US10/650,254 patent/US20040138149A1/en not_active Abandoned
- 2003-08-28 US US10/652,962 patent/US20040043945A1/en not_active Abandoned
- 2003-08-28 US US10/652,655 patent/US7309782B2/en not_active Expired - Fee Related
- 2003-08-28 US US10/652,933 patent/US20050192234A1/en not_active Abandoned
- 2003-10-30 IS IS7007A patent/IS7007A/is unknown
- 2003-11-14 MA MA27397A patent/MA27023A1/fr unknown
- 2003-11-18 BG BG108370A patent/BG108370A/bg unknown
- 2003-11-20 CR CR7159A patent/CR7159A/es not_active Application Discontinuation
- 2003-11-21 NO NO20035177A patent/NO321894B1/no unknown
-
2005
- 2005-05-06 US US11/123,770 patent/US7053192B2/en not_active Expired - Fee Related
- 2005-05-06 US US11/123,703 patent/US7081525B2/en not_active Expired - Fee Related
- 2005-05-06 US US11/123,542 patent/US7105179B2/en not_active Expired - Fee Related
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2006
- 2006-03-03 NO NO20061049A patent/NO20061049L/no unknown
- 2006-03-07 JP JP2006061758A patent/JP4584162B2/ja not_active Expired - Fee Related
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2007
- 2007-02-09 JP JP2007030654A patent/JP2007161726A/ja active Pending