JP2004530137A5 - - Google Patents
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- Publication number
- JP2004530137A5 JP2004530137A5 JP2003500537A JP2003500537A JP2004530137A5 JP 2004530137 A5 JP2004530137 A5 JP 2004530137A5 JP 2003500537 A JP2003500537 A JP 2003500537A JP 2003500537 A JP2003500537 A JP 2003500537A JP 2004530137 A5 JP2004530137 A5 JP 2004530137A5
- Authority
- JP
- Japan
- Prior art keywords
- probe
- measurement
- confocal
- luminescent
- optical
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 238000000034 method Methods 0.000 claims 16
- 230000003287 optical effect Effects 0.000 claims 11
- 238000005259 measurement Methods 0.000 claims 9
- 239000000523 sample Substances 0.000 claims 8
- 239000012491 analyte Substances 0.000 claims 6
- 238000001514 detection method Methods 0.000 claims 5
- 239000003153 chemical reaction reagent Substances 0.000 claims 4
- 230000005284 excitation Effects 0.000 claims 4
- 238000000926 separation method Methods 0.000 claims 3
- 238000004020 luminiscence type Methods 0.000 claims 2
- 238000007899 nucleic acid hybridization Methods 0.000 claims 2
- 238000010791 quenching Methods 0.000 claims 2
- 230000001419 dependent effect Effects 0.000 claims 1
- 230000023077 detection of light stimulus Effects 0.000 claims 1
- 239000012634 fragment Substances 0.000 claims 1
- 238000002844 melting Methods 0.000 claims 1
- 230000008018 melting Effects 0.000 claims 1
- 230000004001 molecular interaction Effects 0.000 claims 1
- 150000007523 nucleic acids Chemical class 0.000 claims 1
- 102000039446 nucleic acids Human genes 0.000 claims 1
- 108020004707 nucleic acids Proteins 0.000 claims 1
- 230000000171 quenching effect Effects 0.000 claims 1
- 230000005855 radiation Effects 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10126083A DE10126083A1 (de) | 2001-05-29 | 2001-05-29 | Verwendung von optischen Diffraktionselementen in Nachweisverfahren |
| PCT/EP2002/005866 WO2002097406A1 (de) | 2001-05-29 | 2002-05-28 | Verwendung von optischen diffraktionselementen in nachweisverfahren |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2004530137A JP2004530137A (ja) | 2004-09-30 |
| JP2004530137A5 true JP2004530137A5 (enExample) | 2006-01-05 |
Family
ID=7686488
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2003500537A Pending JP2004530137A (ja) | 2001-05-29 | 2002-05-28 | 検出法における光学的回折要素の使用 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US7259847B2 (enExample) |
| EP (1) | EP1390725B1 (enExample) |
| JP (1) | JP2004530137A (enExample) |
| CA (1) | CA2449190A1 (enExample) |
| DE (1) | DE10126083A1 (enExample) |
| WO (1) | WO2002097406A1 (enExample) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1637871B1 (en) * | 2003-05-30 | 2011-03-23 | Olympus Corporation | Measuring apparatus including a light-receiving unit |
| DE10336080A1 (de) * | 2003-08-06 | 2005-03-03 | Gnothis Holding Sa | Verfahren und Vorrichtung zur Bestimmung von lumineszierenden Molekülen, insbesondere nach der Methode der Fluoreszenzkorrelationsspektroskopie |
| DE202004012992U1 (de) * | 2004-08-19 | 2005-12-29 | Storz Endoskop Produktions Gmbh | Endoskopisches Video-Meßsystem |
| JP2008523383A (ja) | 2004-12-10 | 2008-07-03 | コーニンクレッカ フィリップス エレクトロニクス エヌ ヴィ | マルチスポット調査装置 |
| DE102005000840B4 (de) * | 2005-01-05 | 2007-12-27 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. | Verfahren und Vorrichtung zur Elementanalyse mittels Laser-Emissionsspektrometrie |
| CN100372947C (zh) * | 2005-03-03 | 2008-03-05 | 华南师范大学 | 转基因物种的荧光相关光谱检测方法 |
| US20100049055A1 (en) * | 2005-05-31 | 2010-02-25 | W.O.M. World Of Medicine Ag | Method and apparatus for visual characterization of tissue |
| US20100167413A1 (en) * | 2007-05-10 | 2010-07-01 | Paul Lundquist | Methods and systems for analyzing fluorescent materials with reduced autofluorescence |
| US20080277595A1 (en) * | 2007-05-10 | 2008-11-13 | Pacific Biosciences Of California, Inc. | Highly multiplexed confocal detection systems and methods of using same |
| AU2008251861B2 (en) * | 2007-05-10 | 2014-03-20 | Pacific Biosciences Of California, Inc. | Methods and systems for analyzing fluorescent materials with reduced autofluorescence |
| DE102010016818A1 (de) * | 2010-03-16 | 2011-09-22 | Leica Microsystems Cms Gmbh | Verfahren und Vorrichtung zur Durchführung von Multipoint-FCS |
| WO2013131888A1 (en) | 2012-03-06 | 2013-09-12 | Rudolf Rigler | Cyclic single molecule sequencing process |
| CN106460034B (zh) | 2014-01-10 | 2021-05-07 | 格诺特斯控股股份公司 | 具有高准确度的单分子分析 |
| EP3112841A1 (en) | 2015-06-30 | 2017-01-04 | Gnothis Holding SA | Single molecule analysis in an electrical field |
| EP3330763A1 (en) | 2016-12-05 | 2018-06-06 | Gnothis AB | Apparatus for characterizing luminescent entities |
| DE102017105113B4 (de) | 2017-03-10 | 2021-09-30 | Leibniz-Institut für Photonische Technologien e.V. (Engl.Leibniz Institute of Photonic Technology) | Anordnung und Verfahren für die Erfassung von Änderungen der optischen Weglänge in einem Nano-Kapillarkanal |
| CN112912715B (zh) * | 2018-10-25 | 2024-08-09 | 浜松光子学株式会社 | 光学测定装置及光学测定方法 |
| EP4379378A1 (en) | 2022-11-29 | 2024-06-05 | Gnothis Holding AG | Selective-area coated protein resistant surface |
| EP4616193A1 (en) | 2022-11-07 | 2025-09-17 | Gnothis Holding AG | Selective-area coated protein resistant surface |
| EP4623095A1 (en) | 2022-11-21 | 2025-10-01 | Gnothis Holding AG | Multiple molecular binding sites |
| EP4403643A1 (en) | 2023-01-19 | 2024-07-24 | Gnothis Holding AG | Multiple molecular binding sites |
| EP4375644A1 (en) | 2022-11-22 | 2024-05-29 | Gnothis Holding AG | Fingerprint analysis of single molecule events |
| EP4379355A1 (en) | 2022-11-29 | 2024-06-05 | Gnothis Holding AG | High throughput analysis of single molecule events |
| EP4382614A1 (en) | 2022-12-06 | 2024-06-12 | Gnothis Holding AG | High yield support |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK0679251T3 (da) | 1993-01-18 | 1999-01-25 | Evotec Biosystems Aktiengesell | Fremgangsmåde og apparat til vurdering af biopolymerers fitness |
| JP3474652B2 (ja) * | 1994-11-11 | 2003-12-08 | 株式会社モリテックス | 多点レーザトラッピング装置及びその方法 |
| DE19748211A1 (de) | 1997-10-31 | 1999-05-06 | Zeiss Carl Fa | Optisches Array-System und Reader für Mikrotiterplatten |
| US6055106A (en) * | 1998-02-03 | 2000-04-25 | Arch Development Corporation | Apparatus for applying optical gradient forces |
| US6208411B1 (en) * | 1998-09-28 | 2001-03-27 | Kla-Tencor Corporation | Massively parallel inspection and imaging system |
| US6455861B1 (en) * | 1998-11-24 | 2002-09-24 | Cambridge Research & Instrumentation, Inc. | Fluorescence polarization assay system and method |
| GB9906929D0 (en) * | 1999-03-26 | 1999-05-19 | Univ Glasgow | Assay system |
| JP2001228756A (ja) * | 2000-02-18 | 2001-08-24 | Canon Inc | 画像形成装置 |
| WO2001063262A1 (en) * | 2000-02-25 | 2001-08-30 | Cambridge Research & Instrumentation Inc. | Multiple label fluorescence polarization assay system and method |
| DE10065632A1 (de) | 2000-05-12 | 2001-11-15 | Smtech Biovision Holding Ag Ec | Verfahren zum Nachweis von Polynukleotiden |
| DE10065626A1 (de) | 2000-06-30 | 2002-01-10 | Smtech Biovision Holding Ag Ec | Einzelmolekül-Sequenzierungsverfahren |
-
2001
- 2001-05-29 DE DE10126083A patent/DE10126083A1/de not_active Withdrawn
-
2002
- 2002-05-28 JP JP2003500537A patent/JP2004530137A/ja active Pending
- 2002-05-28 WO PCT/EP2002/005866 patent/WO2002097406A1/de not_active Ceased
- 2002-05-28 CA CA002449190A patent/CA2449190A1/en not_active Abandoned
- 2002-05-28 EP EP02747328.9A patent/EP1390725B1/de not_active Expired - Lifetime
- 2002-05-28 US US10/479,177 patent/US7259847B2/en not_active Expired - Lifetime
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