JP2004527490A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2004527490A5 JP2004527490A5 JP2002567283A JP2002567283A JP2004527490A5 JP 2004527490 A5 JP2004527490 A5 JP 2004527490A5 JP 2002567283 A JP2002567283 A JP 2002567283A JP 2002567283 A JP2002567283 A JP 2002567283A JP 2004527490 A5 JP2004527490 A5 JP 2004527490A5
- Authority
- JP
- Japan
- Prior art keywords
- agent
- pharmaceutically acceptable
- promoter
- acceptable salt
- organ
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000003795 chemical substances by application Substances 0.000 claims 9
- 210000004698 lymphocyte Anatomy 0.000 claims 7
- 210000000056 organ Anatomy 0.000 claims 7
- 150000003839 salts Chemical class 0.000 claims 7
- 239000008194 pharmaceutical composition Substances 0.000 claims 6
- 210000003734 kidney Anatomy 0.000 claims 5
- 150000001875 compounds Chemical class 0.000 claims 3
- 230000024924 glomerular filtration Effects 0.000 claims 3
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical group [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 claims 2
- 125000000217 alkyl group Chemical group 0.000 claims 2
- 125000004432 carbon atom Chemical group C* 0.000 claims 2
- 239000003018 immunosuppressive agent Substances 0.000 claims 2
- 125000000843 phenylene group Chemical group C1(=C(C=CC=C1)*)* 0.000 claims 2
- 238000011084 recovery Methods 0.000 claims 2
- 229940122739 Calcineurin inhibitor Drugs 0.000 claims 1
- 102100024123 Calcineurin-binding protein cabin-1 Human genes 0.000 claims 1
- 101710192106 Calcineurin-binding protein cabin-1 Proteins 0.000 claims 1
- 239000000969 carrier Substances 0.000 claims 1
- 230000003111 delayed effect Effects 0.000 claims 1
- 239000003085 diluting agent Substances 0.000 claims 1
- KKGQTZUTZRNORY-UHFFFAOYSA-N fingolimod Chemical compound CCCCCCCCC1=CC=C(CCC(N)(CO)CO)C=C1 KKGQTZUTZRNORY-UHFFFAOYSA-N 0.000 claims 1
- 230000002519 immonomodulatory effect Effects 0.000 claims 1
- 239000002955 immunomodulating agent Substances 0.000 claims 1
- 230000002584 immunomodulator Effects 0.000 claims 1
- 229940121354 immunomodulator Drugs 0.000 claims 1
- 229960003444 immunosuppressant agent Drugs 0.000 claims 1
- 230000001861 immunosuppressant effect Effects 0.000 claims 1
- 229940125721 immunosuppressive agent Drugs 0.000 claims 1
- 230000001737 promoting effect Effects 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0104438A GB0104438D0 (en) | 2001-02-22 | 2001-02-22 | Organic compounds |
| GB0105000A GB0105000D0 (en) | 2001-02-28 | 2001-02-28 | Organic compounds |
| PCT/EP2002/001860 WO2002067915A1 (en) | 2001-02-22 | 2002-02-21 | Use of accelerated lymphocyte homing agents for the manufacture of a medicament for the treatment of delayed graft function |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2004527490A JP2004527490A (ja) | 2004-09-09 |
| JP2004527490A5 true JP2004527490A5 (https=) | 2005-05-26 |
| JP4318921B2 JP4318921B2 (ja) | 2009-08-26 |
Family
ID=26245749
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2002567283A Expired - Fee Related JP4318921B2 (ja) | 2001-02-22 | 2002-02-21 | 移植片の機能発現遅延の処置のための医薬の製造のためのリンパ球ホーミング促進剤の使用 |
Country Status (11)
| Country | Link |
|---|---|
| US (2) | US20040087662A1 (https=) |
| EP (1) | EP1368015B1 (https=) |
| JP (1) | JP4318921B2 (https=) |
| CN (1) | CN100479814C (https=) |
| AT (1) | ATE335475T1 (https=) |
| BR (1) | BR0207434A (https=) |
| CA (1) | CA2435739A1 (https=) |
| DE (1) | DE60213766T2 (https=) |
| ES (1) | ES2267993T3 (https=) |
| PT (1) | PT1368015E (https=) |
| WO (1) | WO2002067915A1 (https=) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2322442T3 (es) * | 2001-06-08 | 2009-06-22 | Novartis Ag | Tratamiento o profilaxis del rechazo de injertos de celulas productoras de insulina. |
| BR0306811A (pt) | 2002-01-11 | 2004-10-26 | Sankyo Co | Composto, éster farmacologicamente aceitável do mesmo, composição farmacêutica e métodos para prevenção ou tratamento de doenças autoimunes, da artrite reumatóide e da rejeição causada pelo transplante de vários órgãos em um mamìfero |
| JP2005272453A (ja) | 2004-02-24 | 2005-10-06 | Sankyo Co Ltd | アミノアルコール化合物 |
| CN101014329B (zh) * | 2004-07-16 | 2010-09-08 | 杏林制药株式会社 | 用于对器官或组织的移植的排异反应或骨髓移植的移植物抗宿主反应预防或治疗的药物组合物 |
| EP1806338B1 (en) * | 2004-10-12 | 2016-01-20 | Kyorin Pharmaceutical Co., Ltd. | Process for producing 2-amino-2-[2-[4-(3-benzyloxy-phenylthio)-2-chlorophenyl[ethyl]-1,3-propanediol hydrochloride and hydrates thereof. and intermediates the production thereof |
| SI1932522T1 (sl) * | 2005-10-07 | 2012-08-31 | Kyorin Seiyaku Kk | Terapevtsko sredstvo za jetrno bolezen, ki vsebuje 2-amino-1,3- propandiolni derivat kot aktivno sestavino |
| TWI389683B (zh) * | 2006-02-06 | 2013-03-21 | Kyorin Seiyaku Kk | A therapeutic agent for an inflammatory bowel disease or an inflammatory bowel disease treatment using a 2-amino-1,3-propanediol derivative as an active ingredient |
| MX2009001457A (es) * | 2006-08-08 | 2009-02-19 | Kyorin Seiyaku Kk | Derivados de aminoalcohol e inmunosupresores que contienen lo mismo como ingrediente activo. |
| JP5188972B2 (ja) * | 2006-08-08 | 2013-04-24 | 杏林製薬株式会社 | アミノリン酸エステル誘導体及びそれらを有効成分とするｓ１ｐ受容体調節剤 |
| WO2009099174A1 (ja) | 2008-02-07 | 2009-08-13 | Kyorin Pharmaceutical Co., Ltd. | アミノアルコール誘導体を有効成分とする炎症性腸疾患の治療剤又は予防剤 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3928572A (en) * | 1971-02-11 | 1975-12-23 | Ayerst Mckenna & Harrison | Myriocin and process of preparation |
| US5604229A (en) * | 1992-10-21 | 1997-02-18 | Yoshitomi Pharmaceutical Industries, Ltd. | 2-amino-1,3-propanediol compound and immunosuppressant |
| ES2230571T3 (es) * | 1995-12-28 | 2005-05-01 | Mitsubishi Pharma Corporation | `composicion farmaceutica destinada para la administracion topica que comprende el 2-amino-2-(2-(4-octilfenil)etil) propan-1,3-diol para el tratamiento de las enfermedades causadas por una alteracion inmunitaria. |
| GB9624038D0 (en) * | 1996-11-19 | 1997-01-08 | Sandoz Ltd | Organic compounds |
| ATE298740T1 (de) * | 1997-04-04 | 2005-07-15 | Mitsubishi Pharma Corp | 2-aminopropan-1,3-diol-verbindungen, ihre medizinische anwendung und zwischenprodukte zu ihrer synthese |
| JPH1180026A (ja) * | 1997-09-02 | 1999-03-23 | Yoshitomi Pharmaceut Ind Ltd | 新規免疫抑制剤、その使用方法およびその同定方法 |
| ES2322442T3 (es) * | 2001-06-08 | 2009-06-22 | Novartis Ag | Tratamiento o profilaxis del rechazo de injertos de celulas productoras de insulina. |
-
2002
- 2002-02-21 ES ES02711877T patent/ES2267993T3/es not_active Expired - Lifetime
- 2002-02-21 AT AT02711877T patent/ATE335475T1/de not_active IP Right Cessation
- 2002-02-21 CA CA002435739A patent/CA2435739A1/en not_active Abandoned
- 2002-02-21 JP JP2002567283A patent/JP4318921B2/ja not_active Expired - Fee Related
- 2002-02-21 BR BR0207434-6A patent/BR0207434A/pt not_active IP Right Cessation
- 2002-02-21 CN CNB028053958A patent/CN100479814C/zh not_active Expired - Fee Related
- 2002-02-21 DE DE60213766T patent/DE60213766T2/de not_active Expired - Fee Related
- 2002-02-21 US US10/468,471 patent/US20040087662A1/en not_active Abandoned
- 2002-02-21 PT PT02711877T patent/PT1368015E/pt unknown
- 2002-02-21 WO PCT/EP2002/001860 patent/WO2002067915A1/en not_active Ceased
- 2002-02-21 EP EP02711877A patent/EP1368015B1/en not_active Expired - Lifetime
-
2007
- 2007-09-26 US US11/861,586 patent/US20080015261A1/en not_active Abandoned
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| RU2487119C2 (ru) | Производные иминопиридина и их применение в качестве микробиоцидов | |
| JP2004527490A5 (https=) | ||
| JP2005529182A5 (https=) | ||
| JP2010515731A5 (https=) | ||
| EP2340830A3 (en) | Hepatitis C Virus Inhibitors | |
| JP2017535610A5 (https=) | ||
| JP2016505595A5 (https=) | ||
| RU2006113600A (ru) | Неседативный а-2-агонист 1-(2,3-диметил-фенил)-этил-1,3-дигидро-имидазол-2-тион | |
| JP2007510662A5 (https=) | ||
| WO2005095403B1 (en) | Macrocyclic compounds as inhibitors of viral replication | |
| JP2005526857A5 (https=) | ||
| RU2009115963A (ru) | Производные оксадиазола, обладающие противовоспалительными и иммунодепрессантными свойствами | |
| EP2311851A3 (en) | Inhibitors of serine proteases, particularly HCV NS3-NS4A protease | |
| JP2010530881A5 (https=) | ||
| EA200800932A1 (ru) | Модифицированные 4`-нуклеозиды в качестве противовирусных агентов | |
| EP1862458A3 (en) | Therapeutic agents useful for treating pain | |
| RU2011133900A (ru) | Аналоги циклоспорина для предупреждения или лечения инфекции гепатита с | |
| WO2006039668B1 (en) | 3-ether and 3-thioether substituted cyclosporin derivatives for the treatment and prevention of hepatitis c infection | |
| RU2012117829A (ru) | Фосфорамидатные производные нуклеозидов | |
| JP2009541225A5 (https=) | ||
| JP2004534788A5 (https=) | ||
| JP2002519355A5 (https=) | ||
| JP2005536503A5 (https=) | ||
| JP2010500962A5 (https=) | ||
| JP2004131511A5 (https=) |