JP2004527490A5 - - Google Patents
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- Publication number
- JP2004527490A5 JP2004527490A5 JP2002567283A JP2002567283A JP2004527490A5 JP 2004527490 A5 JP2004527490 A5 JP 2004527490A5 JP 2002567283 A JP2002567283 A JP 2002567283A JP 2002567283 A JP2002567283 A JP 2002567283A JP 2004527490 A5 JP2004527490 A5 JP 2004527490A5
- Authority
- JP
- Japan
- Prior art keywords
- agent
- pharmaceutically acceptable
- promoter
- acceptable salt
- organ
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000003795 chemical substances by application Substances 0.000 claims 9
- 210000004698 lymphocyte Anatomy 0.000 claims 7
- 210000000056 organ Anatomy 0.000 claims 7
- 150000003839 salts Chemical class 0.000 claims 7
- 239000008194 pharmaceutical composition Substances 0.000 claims 6
- 210000003734 kidney Anatomy 0.000 claims 5
- 150000001875 compounds Chemical class 0.000 claims 3
- 230000024924 glomerular filtration Effects 0.000 claims 3
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical group [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 claims 2
- 125000000217 alkyl group Chemical group 0.000 claims 2
- 125000004432 carbon atom Chemical group C* 0.000 claims 2
- 239000003018 immunosuppressive agent Substances 0.000 claims 2
- 125000000843 phenylene group Chemical group C1(=C(C=CC=C1)*)* 0.000 claims 2
- 238000011084 recovery Methods 0.000 claims 2
- 229940122739 Calcineurin inhibitor Drugs 0.000 claims 1
- 102100024123 Calcineurin-binding protein cabin-1 Human genes 0.000 claims 1
- 101710192106 Calcineurin-binding protein cabin-1 Proteins 0.000 claims 1
- 239000000969 carrier Substances 0.000 claims 1
- 230000003111 delayed effect Effects 0.000 claims 1
- 239000003085 diluting agent Substances 0.000 claims 1
- KKGQTZUTZRNORY-UHFFFAOYSA-N fingolimod Chemical compound CCCCCCCCC1=CC=C(CCC(N)(CO)CO)C=C1 KKGQTZUTZRNORY-UHFFFAOYSA-N 0.000 claims 1
- 230000002519 immonomodulatory effect Effects 0.000 claims 1
- 239000002955 immunomodulating agent Substances 0.000 claims 1
- 230000002584 immunomodulator Effects 0.000 claims 1
- 229940121354 immunomodulator Drugs 0.000 claims 1
- 229960003444 immunosuppressant agent Drugs 0.000 claims 1
- 230000001861 immunosuppressant effect Effects 0.000 claims 1
- 229940125721 immunosuppressive agent Drugs 0.000 claims 1
- 230000001737 promoting effect Effects 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0104438A GB0104438D0 (en) | 2001-02-22 | 2001-02-22 | Organic compounds |
| GB0105000A GB0105000D0 (en) | 2001-02-28 | 2001-02-28 | Organic compounds |
| PCT/EP2002/001860 WO2002067915A1 (en) | 2001-02-22 | 2002-02-21 | Use of accelerated lymphocyte homing agents for the manufacture of a medicament for the treatment of delayed graft function |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2004527490A JP2004527490A (ja) | 2004-09-09 |
| JP2004527490A5 true JP2004527490A5 (https=) | 2005-05-26 |
| JP4318921B2 JP4318921B2 (ja) | 2009-08-26 |
Family
ID=26245749
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2002567283A Expired - Fee Related JP4318921B2 (ja) | 2001-02-22 | 2002-02-21 | 移植片の機能発現遅延の処置のための医薬の製造のためのリンパ球ホーミング促進剤の使用 |
Country Status (11)
| Country | Link |
|---|---|
| US (2) | US20040087662A1 (https=) |
| EP (1) | EP1368015B1 (https=) |
| JP (1) | JP4318921B2 (https=) |
| CN (1) | CN100479814C (https=) |
| AT (1) | ATE335475T1 (https=) |
| BR (1) | BR0207434A (https=) |
| CA (1) | CA2435739A1 (https=) |
| DE (1) | DE60213766T2 (https=) |
| ES (1) | ES2267993T3 (https=) |
| PT (1) | PT1368015E (https=) |
| WO (1) | WO2002067915A1 (https=) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BR0209319A (pt) * | 2001-06-08 | 2004-07-20 | Novartis Ag | Tratamento ou profilaxia de rejeição de enxerto de célula produtora de insulina |
| DK1471054T3 (da) | 2002-01-11 | 2009-11-09 | Daiichi Sankyo Co Ltd | Aminoalkohol-derivat eller phosphonsyre-derivat og medicinsk sammensætning, der indeholder disse |
| NZ549162A (en) | 2004-02-24 | 2009-12-24 | Sankyo Co | Amino-pyrrol alcohol compounds |
| US7781617B2 (en) * | 2004-07-16 | 2010-08-24 | Kyorin Pharmaceutical Co., Ltd | Effective use method of medicaments and method of preventing expression of side effect |
| EP1806338B1 (en) * | 2004-10-12 | 2016-01-20 | Kyorin Pharmaceutical Co., Ltd. | Process for producing 2-amino-2-[2-[4-(3-benzyloxy-phenylthio)-2-chlorophenyl[ethyl]-1,3-propanediol hydrochloride and hydrates thereof. and intermediates the production thereof |
| PL1932522T3 (pl) * | 2005-10-07 | 2012-09-28 | Kyorin Seiyaku Kk | Środek terapeutyczny do leczenia choroby wątroby zawierający jako składnik czynny pochodną 2-amino-1,3-propanodiolu |
| TWI389683B (zh) * | 2006-02-06 | 2013-03-21 | Kyorin Seiyaku Kk | A therapeutic agent for an inflammatory bowel disease or an inflammatory bowel disease treatment using a 2-amino-1,3-propanediol derivative as an active ingredient |
| CA2659598A1 (en) * | 2006-08-08 | 2008-02-14 | Kyorin Pharmaceutical Co., Ltd. | Amino phosphate derivative and s1p receptor modulator having same as an active ingredient |
| JP5140593B2 (ja) * | 2006-08-08 | 2013-02-06 | 杏林製薬株式会社 | アミノアルコール誘導体及びそれらを有効成分とする免疫抑制剤 |
| TW200946105A (en) | 2008-02-07 | 2009-11-16 | Kyorin Seiyaku Kk | Therapeutic agent or preventive agent for inflammatory bowel disease containing amino alcohol derivative as active ingredient |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3928572A (en) * | 1971-02-11 | 1975-12-23 | Ayerst Mckenna & Harrison | Myriocin and process of preparation |
| DE69321823T2 (de) * | 1992-10-21 | 1999-06-02 | Taito Co., Ltd., Tokio/Tokyo | 2-amino-1, 3- propandiolverbindung und immunosuppressium |
| WO1997024112A1 (en) * | 1995-12-28 | 1997-07-10 | Yoshitomi Pharmaceutical Industries, Ltd. | External preparation |
| GB9624038D0 (en) * | 1996-11-19 | 1997-01-08 | Sandoz Ltd | Organic compounds |
| ES2240868T3 (es) * | 1997-04-04 | 2005-10-16 | Mitsubishi Pharma Corporation | Compuesto de 2-aminopropano -1,3-diol, su uso farmaceutico e intermedios en su sintesis. |
| JPH1180026A (ja) * | 1997-09-02 | 1999-03-23 | Yoshitomi Pharmaceut Ind Ltd | 新規免疫抑制剤、その使用方法およびその同定方法 |
| BR0209319A (pt) * | 2001-06-08 | 2004-07-20 | Novartis Ag | Tratamento ou profilaxia de rejeição de enxerto de célula produtora de insulina |
-
2002
- 2002-02-21 JP JP2002567283A patent/JP4318921B2/ja not_active Expired - Fee Related
- 2002-02-21 BR BR0207434-6A patent/BR0207434A/pt not_active IP Right Cessation
- 2002-02-21 AT AT02711877T patent/ATE335475T1/de not_active IP Right Cessation
- 2002-02-21 US US10/468,471 patent/US20040087662A1/en not_active Abandoned
- 2002-02-21 CN CNB028053958A patent/CN100479814C/zh not_active Expired - Fee Related
- 2002-02-21 EP EP02711877A patent/EP1368015B1/en not_active Expired - Lifetime
- 2002-02-21 PT PT02711877T patent/PT1368015E/pt unknown
- 2002-02-21 DE DE60213766T patent/DE60213766T2/de not_active Expired - Fee Related
- 2002-02-21 CA CA002435739A patent/CA2435739A1/en not_active Abandoned
- 2002-02-21 ES ES02711877T patent/ES2267993T3/es not_active Expired - Lifetime
- 2002-02-21 WO PCT/EP2002/001860 patent/WO2002067915A1/en not_active Ceased
-
2007
- 2007-09-26 US US11/861,586 patent/US20080015261A1/en not_active Abandoned
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