JP2004524299A - アミノアセトニトリル化合物を含有する薬学的組成物および動物における体内寄生性害虫を処置する薬学的組成物を調製するためのその使用 - Google Patents
アミノアセトニトリル化合物を含有する薬学的組成物および動物における体内寄生性害虫を処置する薬学的組成物を調製するためのその使用 Download PDFInfo
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- JP2004524299A JP2004524299A JP2002560463A JP2002560463A JP2004524299A JP 2004524299 A JP2004524299 A JP 2004524299A JP 2002560463 A JP2002560463 A JP 2002560463A JP 2002560463 A JP2002560463 A JP 2002560463A JP 2004524299 A JP2004524299 A JP 2004524299A
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- Prior art keywords
- halo
- alkyl
- alkoxy
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- alkylthio
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- 125000001424 substituent group Chemical group 0.000 claims description 92
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- 125000004093 cyano group Chemical group *C#N 0.000 claims description 41
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- 125000003545 alkoxy group Chemical group 0.000 claims description 17
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- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 claims description 12
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- JWVCLYRUEFBMGU-UHFFFAOYSA-N quinazoline Chemical compound N1=CN=CC2=CC=CC=C21 JWVCLYRUEFBMGU-UHFFFAOYSA-N 0.000 description 1
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/275—Nitriles; Isonitriles
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N37/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids
- A01N37/44—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing at least one carboxylic group or a thio analogue, or a derivative thereof, and a nitrogen atom attached to the same carbon skeleton by a single or double bond, this nitrogen atom not being a member of a derivative or of a thio analogue of a carboxylic group, e.g. amino-carboxylic acids
- A01N37/46—N-acyl derivatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/275—Nitriles; Isonitriles
- A61K31/277—Nitriles; Isonitriles having a ring, e.g. verapamil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/10—Anthelmintics
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Environmental Sciences (AREA)
- Wood Science & Technology (AREA)
- Pest Control & Pesticides (AREA)
- Engineering & Computer Science (AREA)
- Dentistry (AREA)
- Agronomy & Crop Science (AREA)
- Zoology (AREA)
- Plant Pathology (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Tropical Medicine & Parasitology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH972001 | 2001-01-22 | ||
| PCT/EP2002/000568 WO2002060257A1 (en) | 2001-01-22 | 2002-01-21 | Pharmaceutical composition containing aminoacetonitril compounds and the use thereof for the preparation of a pharmaceutical composition for the treatment of endoparasitic pests in animals |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2004524299A true JP2004524299A (ja) | 2004-08-12 |
| JP2004524299A5 JP2004524299A5 (cg-RX-API-DMAC7.html) | 2005-06-02 |
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| JP2002560463A Pending JP2004524299A (ja) | 2001-01-22 | 2002-01-21 | アミノアセトニトリル化合物を含有する薬学的組成物および動物における体内寄生性害虫を処置する薬学的組成物を調製するためのその使用 |
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| US (2) | US7052707B2 (cg-RX-API-DMAC7.html) |
| EP (1) | EP1367891A1 (cg-RX-API-DMAC7.html) |
| JP (1) | JP2004524299A (cg-RX-API-DMAC7.html) |
| KR (1) | KR20030063373A (cg-RX-API-DMAC7.html) |
| CN (1) | CN1487788A (cg-RX-API-DMAC7.html) |
| AR (1) | AR035531A1 (cg-RX-API-DMAC7.html) |
| AU (1) | AU2002250841B2 (cg-RX-API-DMAC7.html) |
| BR (1) | BR0206576A (cg-RX-API-DMAC7.html) |
| CA (1) | CA2429493A1 (cg-RX-API-DMAC7.html) |
| MX (1) | MXPA03006526A (cg-RX-API-DMAC7.html) |
| NZ (1) | NZ525874A (cg-RX-API-DMAC7.html) |
| RU (1) | RU2282357C2 (cg-RX-API-DMAC7.html) |
| WO (1) | WO2002060257A1 (cg-RX-API-DMAC7.html) |
| ZA (1) | ZA200304017B (cg-RX-API-DMAC7.html) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2006043654A1 (ja) * | 2004-10-22 | 2006-04-27 | Nihon Nohyaku Co., Ltd. | アセトニトリル誘導体及び有害生物防除剤並びにその使用方法 |
| JP2007513911A (ja) * | 2003-12-10 | 2007-05-31 | ノバルティス アクチエンゲゼルシャフト | アミドアセトニトリル誘導体 |
| JP2010519249A (ja) * | 2007-02-21 | 2010-06-03 | ファイザー・リミテッド | ベンゾフラン抗寄生虫剤 |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2002049641A2 (en) * | 2000-12-20 | 2002-06-27 | Novartis Ag | Anti-endoparasitic amidoacetonitrils |
| AR040082A1 (es) * | 2002-05-22 | 2005-03-16 | Novartis Ag | Derivados de n-acilaminoacetonitrilo y su uso para el control de parasitos |
| TW200400932A (en) * | 2002-06-19 | 2004-01-16 | Novartis Ag | Organic compounds |
| GB0402677D0 (en) | 2003-11-06 | 2004-03-10 | Novartis Ag | Organic compounds |
| AU2004293075A1 (en) * | 2003-11-20 | 2005-06-09 | Angiotech International Ag | Soft tissue implants and anti-scarring agents |
| AR049391A1 (es) * | 2004-06-10 | 2006-07-26 | Novartis Ag | Derivados de aminoacetonitrilo y su uso para controlar parasitos en animales de sangre caliente |
| MX2009007482A (es) | 2007-02-09 | 2009-08-13 | Pfizer Ltd | Agentes antiparasitarios. |
| PT2155699E (pt) * | 2007-05-15 | 2015-11-12 | Merial Inc | Compostos de ariloazol-2-il-cianoetilamino, método de fabrico e método de utilização |
| WO2010025451A2 (en) | 2008-08-29 | 2010-03-04 | Dow Agrosciences Llc | 5,8-difluoro-4-(2-(4-(heteroaryloxy)-phenyl)ethylamino)quinazolines and their use as agrochemicals |
| CA2741186C (en) * | 2008-10-21 | 2016-07-19 | Merial Limited | Thioamide compounds, method of making and method of using thereof |
| CA2945453C (en) * | 2008-11-14 | 2021-03-02 | Merial, Inc. | Enantiomerically enriched aryloazol-2-yl cyanoethylamino paraciticidal compounds |
| GB0905365D0 (en) | 2009-03-27 | 2009-05-13 | Norbrook Lab Ltd | A topical parasiticide composition |
| RU2413513C2 (ru) * | 2009-04-06 | 2011-03-10 | Государственное образовательное учреждение высшего профессионального образования "Казанский государственный университет им. В.И. Ульянова-Ленина" | Антигельминтная композиция на основе соли четвертичного фосфония и замещенного динитробензофуроксана |
| RU2452180C2 (ru) * | 2010-08-31 | 2012-06-10 | Общество с ограниченной ответственностью "Научно-внедренческое предприятие "Астрафарм" | Комплексная антипаразитарная композиция |
| US8822689B2 (en) | 2012-09-19 | 2014-09-02 | Merial Limited | Aryloazol-2-yl cyanoethylamino compounds, method of making and method of using thereof |
| AR094961A1 (es) | 2013-03-15 | 2015-09-09 | Lilly Co Eli | 1-hidroxi-benzooxaboroles como agentes antiparasitarios |
| US9907778B2 (en) | 2013-09-13 | 2018-03-06 | Pitney Pharmaceuticals Pty Limited | Anticancer agent comprising aminoacetonitrile compound as active ingredient |
| EP3261636A1 (en) | 2015-02-24 | 2018-01-03 | Pitney Pharmaceuticals Pty Limited | Anti cancer agent comprising aminoacetonitrile compound as active ingredient |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH04198158A (ja) * | 1990-11-29 | 1992-07-17 | Hokko Chem Ind Co Ltd | ベンズアミド誘導体および除草剤 |
| DE69607974T2 (de) * | 1995-05-31 | 2000-10-05 | Ihara Chemical Industry Co., Ltd. | Phenylalkanamid-derivate und land- und gartenbauwirtschaftliche baterizide |
| US6239077B1 (en) * | 1998-05-01 | 2001-05-29 | Nihon Nohyaku Co., Ltd. | Aminoacetonitrile derivative agricultural and horticultural insecticide containing the same and use thereof |
| EP1343506A1 (de) * | 2000-12-19 | 2003-09-17 | MERCK PATENT GmbH | Pharmazeutische formulierung enthaltend pyrazolo 4,3-d]pyrimidine und antithrombotica, calcium-antagonisten, prostaglandine oder prostaglandinderivate |
| WO2002049641A2 (en) * | 2000-12-20 | 2002-06-27 | Novartis Ag | Anti-endoparasitic amidoacetonitrils |
| WO2002050052A1 (en) | 2000-12-20 | 2002-06-27 | Syngenta Participations Ag | N-acyl aminoacetonitriles having pesticidal properties |
-
2002
- 2002-01-18 AR ARP020100190A patent/AR035531A1/es not_active Application Discontinuation
- 2002-01-21 WO PCT/EP2002/000568 patent/WO2002060257A1/en not_active Ceased
- 2002-01-21 RU RU2003124076/04A patent/RU2282357C2/ru not_active IP Right Cessation
- 2002-01-21 AU AU2002250841A patent/AU2002250841B2/en not_active Ceased
- 2002-01-21 JP JP2002560463A patent/JP2004524299A/ja active Pending
- 2002-01-21 MX MXPA03006526A patent/MXPA03006526A/es unknown
- 2002-01-21 CA CA002429493A patent/CA2429493A1/en not_active Abandoned
- 2002-01-21 NZ NZ525874A patent/NZ525874A/en unknown
- 2002-01-21 EP EP02719711A patent/EP1367891A1/en not_active Withdrawn
- 2002-01-21 KR KR10-2003-7006238A patent/KR20030063373A/ko not_active Ceased
- 2002-01-21 US US10/466,824 patent/US7052707B2/en not_active Expired - Fee Related
- 2002-01-21 CN CNA028039955A patent/CN1487788A/zh active Pending
- 2002-01-21 BR BR0206576-2A patent/BR0206576A/pt not_active IP Right Cessation
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2003
- 2003-05-23 ZA ZA200304017A patent/ZA200304017B/en unknown
- 2003-10-02 US US10/677,972 patent/US7063856B2/en not_active Expired - Fee Related
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2007513911A (ja) * | 2003-12-10 | 2007-05-31 | ノバルティス アクチエンゲゼルシャフト | アミドアセトニトリル誘導体 |
| WO2006043654A1 (ja) * | 2004-10-22 | 2006-04-27 | Nihon Nohyaku Co., Ltd. | アセトニトリル誘導体及び有害生物防除剤並びにその使用方法 |
| JP2010519249A (ja) * | 2007-02-21 | 2010-06-03 | ファイザー・リミテッド | ベンゾフラン抗寄生虫剤 |
Also Published As
| Publication number | Publication date |
|---|---|
| KR20030063373A (ko) | 2003-07-28 |
| ZA200304017B (en) | 2004-07-09 |
| EP1367891A1 (en) | 2003-12-10 |
| AU2002250841B2 (en) | 2005-03-03 |
| US20040063766A1 (en) | 2004-04-01 |
| CA2429493A1 (en) | 2002-08-08 |
| WO2002060257A1 (en) | 2002-08-08 |
| RU2282357C2 (ru) | 2006-08-27 |
| CN1487788A (zh) | 2004-04-07 |
| AR035531A1 (es) | 2004-06-02 |
| NZ525874A (en) | 2005-09-30 |
| MXPA03006526A (es) | 2003-09-22 |
| US7063856B2 (en) | 2006-06-20 |
| US20040044074A1 (en) | 2004-03-04 |
| BR0206576A (pt) | 2003-12-16 |
| RU2003124076A (ru) | 2005-03-10 |
| US7052707B2 (en) | 2006-05-30 |
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