JP2004522781A5 - - Google Patents
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- Publication number
- JP2004522781A5 JP2004522781A5 JP2002567304A JP2002567304A JP2004522781A5 JP 2004522781 A5 JP2004522781 A5 JP 2004522781A5 JP 2002567304 A JP2002567304 A JP 2002567304A JP 2002567304 A JP2002567304 A JP 2002567304A JP 2004522781 A5 JP2004522781 A5 JP 2004522781A5
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- optionally substituted
- compound
- coor
- cooh
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 0 CC(C)c1c(C)c(*)c(C(C*)CN2C(*)=O)c2c1* Chemical compound CC(C)c1c(C)c(*)c(C(C*)CN2C(*)=O)c2c1* 0.000 description 2
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP01301609 | 2001-02-22 | ||
| PCT/GB2002/000785 WO2002067937A1 (en) | 2001-02-22 | 2002-02-22 | Indoline and tetrahydro-quinolines as prodrugs for tumour treatment |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2004522781A JP2004522781A (ja) | 2004-07-29 |
| JP2004522781A5 true JP2004522781A5 (enExample) | 2006-01-05 |
Family
ID=8181734
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2002567304A Pending JP2004522781A (ja) | 2001-02-22 | 2002-02-22 | 腫瘍処置のためのプロドラッグとしてのインドリンおよびテトラヒドロ−キノリン |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US7179921B2 (enExample) |
| EP (1) | EP1408970B1 (enExample) |
| JP (1) | JP2004522781A (enExample) |
| AT (1) | ATE361750T1 (enExample) |
| DE (1) | DE60220057T2 (enExample) |
| ES (1) | ES2287256T3 (enExample) |
| WO (1) | WO2002067937A1 (enExample) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP4862120B2 (ja) * | 2001-02-22 | 2012-01-25 | ユニヴァーシティ オブ ブラッドフォード | 腫瘍治療のためのプロドラッグとしてのベンズ−インドールおよびベンゾ−キノリン誘導体 |
| FR2825705B1 (fr) * | 2001-06-08 | 2005-05-20 | Aventis Pharma Sa | Nouveaux composes heterocycliques, leur preparation et leur utilisation comme medicaments, notamment comme anti-bacteriens |
| FR2835186B1 (fr) | 2002-01-28 | 2006-10-20 | Aventis Pharma Sa | Nouveaux composes heterocycliques, actifs comme inhibiteurs de beta-lactamases |
| FR2844273B1 (fr) | 2002-09-05 | 2008-04-04 | Aventis Pharma Sa | Nouveaux composes heterocycliques, procede et intermediaires de preparation et utilisation comme medicament, notamment comme inhibiteurs de beta-lactamases et anti-bacteriens. |
| GB0302094D0 (en) | 2003-01-29 | 2003-02-26 | Pharmagene Lab Ltd | EP4 receptor antagonists |
| GB0324269D0 (en) | 2003-10-16 | 2003-11-19 | Pharmagene Lab Ltd | EP4 receptor antagonists |
| GB0505644D0 (en) | 2005-03-18 | 2005-04-27 | Univ London Pharmacy | Analogues of the azinomycins as anti-tumour agents and as prodrugs |
| MX2008009956A (es) * | 2006-02-02 | 2008-12-12 | Syntarga Bv | Analogos de cc-1065 solubles en agua y sus conjugados. |
| US9901567B2 (en) | 2007-08-01 | 2018-02-27 | Syntarga B.V. | Substituted CC-1065 analogs and their conjugates |
| HUE035798T2 (en) | 2008-11-03 | 2018-05-28 | Syntarga Bv | CC-1065 analogues and conjugates |
| NO3056203T3 (enExample) | 2010-04-21 | 2018-05-12 | ||
| TR201810856T4 (tr) | 2014-01-10 | 2018-08-27 | Synthon Biopharmaceuticals Bv | CYS'le bağlı antikor-ilaç konjugatlarını saflaştırmak için usul. |
| US10973920B2 (en) | 2014-06-30 | 2021-04-13 | Glykos Finland Oy | Saccharide derivative of a toxic payload and antibody conjugates thereof |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5214065A (en) * | 1990-06-11 | 1993-05-25 | Kyowa Hakko Kogyo Co., Ltd. | Dc-89 derivatives |
| EP0702004A2 (de) * | 1994-09-15 | 1996-03-20 | Ciba-Geigy Ag | 2,9-Diamino- und 2-amino-8-carbamoyl-4-hydroxy-alkansäureamid-derivative |
| JPH08143565A (ja) * | 1994-11-16 | 1996-06-04 | Fujisawa Pharmaceut Co Ltd | ベンズアミド化合物 |
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2002
- 2002-02-22 US US10/468,743 patent/US7179921B2/en not_active Expired - Fee Related
- 2002-02-22 EP EP02712112A patent/EP1408970B1/en not_active Expired - Lifetime
- 2002-02-22 WO PCT/GB2002/000785 patent/WO2002067937A1/en not_active Ceased
- 2002-02-22 JP JP2002567304A patent/JP2004522781A/ja active Pending
- 2002-02-22 AT AT02712112T patent/ATE361750T1/de not_active IP Right Cessation
- 2002-02-22 ES ES02712112T patent/ES2287256T3/es not_active Expired - Lifetime
- 2002-02-22 DE DE60220057T patent/DE60220057T2/de not_active Expired - Lifetime