JP2004519418A5 - - Google Patents
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- Publication number
- JP2004519418A5 JP2004519418A5 JP2002511766A JP2002511766A JP2004519418A5 JP 2004519418 A5 JP2004519418 A5 JP 2004519418A5 JP 2002511766 A JP2002511766 A JP 2002511766A JP 2002511766 A JP2002511766 A JP 2002511766A JP 2004519418 A5 JP2004519418 A5 JP 2004519418A5
- Authority
- JP
- Japan
- Prior art keywords
- thyroid hormone
- composition
- compound
- concentration
- receptor
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000000556 agonist Substances 0.000 description 9
- 150000001875 compounds Chemical class 0.000 description 9
- 230000003054 hormonal effect Effects 0.000 description 9
- 210000001685 thyroid gland Anatomy 0.000 description 9
- 239000005495 thyroid hormone Substances 0.000 description 8
- 229940036555 thyroid hormone Drugs 0.000 description 8
- -1 thyroid hormone compound Chemical class 0.000 description 8
- 239000003446 ligand Substances 0.000 description 6
- 102100031241 Thioredoxin reductase 2, mitochondrial Human genes 0.000 description 3
- 108010071769 Thyroid Hormone Receptors beta Proteins 0.000 description 3
- 238000010494 dissociation reaction Methods 0.000 description 3
- 230000005593 dissociations Effects 0.000 description 3
- 108020003175 receptors Proteins 0.000 description 3
- 108091008763 thyroid hormone receptors α Proteins 0.000 description 3
- 230000000699 topical effect Effects 0.000 description 3
- 235000014113 dietary fatty acids Nutrition 0.000 description 2
- 150000002148 esters Chemical class 0.000 description 2
- 229930195729 fatty acid Natural products 0.000 description 2
- 239000000194 fatty acid Substances 0.000 description 2
- 150000004665 fatty acids Chemical class 0.000 description 2
- 210000003491 skin Anatomy 0.000 description 2
- 150000003626 triacylglycerols Chemical class 0.000 description 2
- 206010003694 Atrophy Diseases 0.000 description 1
- 208000034656 Contusions Diseases 0.000 description 1
- PVNIQBQSYATKKL-UHFFFAOYSA-N Glycerol trihexadecanoate Natural products CCCCCCCCCCCCCCCC(=O)OCC(OC(=O)CCCCCCCCCCCCCCC)COC(=O)CCCCCCCCCCCCCCC PVNIQBQSYATKKL-UHFFFAOYSA-N 0.000 description 1
- 230000037444 atrophy Effects 0.000 description 1
- 210000004207 dermis Anatomy 0.000 description 1
- 230000002500 effect on skin Effects 0.000 description 1
- 150000003839 salts Chemical class 0.000 description 1
- 238000001356 surgical procedure Methods 0.000 description 1
- UOWZUVNAGUAEQC-UHFFFAOYSA-N tiratricol Chemical compound IC1=CC(CC(=O)O)=CC(I)=C1OC1=CC=C(O)C(I)=C1 UOWZUVNAGUAEQC-UHFFFAOYSA-N 0.000 description 1
- PHYFQTYBJUILEZ-IUPFWZBJSA-N triolein Chemical compound CCCCCCCC\C=C/CCCCCCCC(=O)OCC(OC(=O)CCCCCCC\C=C/CCCCCCCC)COC(=O)CCCCCCC\C=C/CCCCCCCC PHYFQTYBJUILEZ-IUPFWZBJSA-N 0.000 description 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/617,052 US6380255B1 (en) | 1995-06-07 | 2000-07-14 | Treatment for dermal skin atrophy using thyroid hormone compounds or thyroid hormone-like compounds |
| PCT/GB2001/003182 WO2002005834A2 (en) | 2000-07-14 | 2001-07-16 | Novel uses for thyroid hormones or thyroid hormone-like agonist compounds for treating dermis conditions |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012049349A Division JP2012144544A (ja) | 2000-07-14 | 2012-03-06 | 甲状腺ホルモンまたは甲状腺ホルモン様アゴニスト化合物 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2004519418A JP2004519418A (ja) | 2004-07-02 |
| JP2004519418A5 true JP2004519418A5 (enExample) | 2008-10-02 |
Family
ID=24472066
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2002511766A Pending JP2004519418A (ja) | 2000-07-14 | 2001-07-16 | 甲状腺ホルモンまたは甲状腺ホルモン様アゴニスト化合物 |
| JP2012049349A Pending JP2012144544A (ja) | 2000-07-14 | 2012-03-06 | 甲状腺ホルモンまたは甲状腺ホルモン様アゴニスト化合物 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012049349A Pending JP2012144544A (ja) | 2000-07-14 | 2012-03-06 | 甲状腺ホルモンまたは甲状腺ホルモン様アゴニスト化合物 |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US6380255B1 (enExample) |
| EP (1) | EP1328265A2 (enExample) |
| JP (2) | JP2004519418A (enExample) |
| AU (1) | AU2001270831A1 (enExample) |
| CA (1) | CA2415285A1 (enExample) |
| WO (1) | WO2002005834A2 (enExample) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2260992C (en) | 1996-08-20 | 2004-03-09 | The Regents Of The University Of California | Eye treatments using synthetic thyroid hormone compositions |
| FI107018B (fi) * | 2000-04-06 | 2001-05-31 | Ipsat Therapies Oy | Dermatologinen käyttö ja valmiste |
| GB0111314D0 (en) * | 2001-05-09 | 2001-07-04 | Karobio Ab | Dermatological formulations |
| JP4473491B2 (ja) * | 2002-05-28 | 2010-06-02 | 株式会社資生堂 | 毛穴縮小剤 |
| EP2428516A1 (en) * | 2003-11-19 | 2012-03-14 | Metabasis Therapeutics, Inc. | Novel phosphorus-containing thyromimetics |
| US7919533B2 (en) * | 2004-10-20 | 2011-04-05 | Sal Abraham | Diiodothyroacetic acid and method of use |
| US20090232879A1 (en) | 2005-05-26 | 2009-09-17 | Metabasis Therapeutics, Inc. | Thyromimetics for the Treatment of Fatty Liver Diseases |
| RU2007148927A (ru) * | 2005-05-26 | 2009-07-10 | Метабэйзис Терапьютикс, Инк. (Us) | Новые тиреомиметики, содержащие фосфиновую кислоту |
| WO2007002036A1 (en) * | 2005-06-24 | 2007-01-04 | Thomas Lavin | Tyroid hormone in burn and adipose deposites |
| WO2007059039A1 (en) * | 2005-11-11 | 2007-05-24 | Oregon Health & Science University | Thyroxine derivatives for preconditioning against stroke |
| US7708699B2 (en) * | 2005-11-18 | 2010-05-04 | Daag International, Inc. | Reflexometry and hormone function |
| US8680973B2 (en) | 2006-06-21 | 2014-03-25 | Neology, Inc. | Systems and methods for synchronizing a plurality of RFID interrogators in a theatre of operation |
| US20090131380A1 (en) * | 2007-11-16 | 2009-05-21 | Pekka Heino | Novel pharmaceutical composition for topical treatment of skin psoriasis and the treatment method thereof |
| WO2018094265A2 (en) | 2016-11-21 | 2018-05-24 | Viking Therapeutics, Inc. | Method of treating glycogen storage disease |
| AU2018280118B2 (en) | 2017-06-05 | 2021-07-15 | Viking Therapeutics, Inc. | Compositions for the treatment of fibrosis |
| EA202091979A1 (ru) | 2018-03-22 | 2021-06-22 | Вайкинг Терапьютикс, Инк. | Кристаллические формы и способы получения кристаллических форм соединения |
| EP4775207A2 (en) | 2018-12-05 | 2026-07-15 | Viking Therapeutics, Inc. | Compositions for the treatment of fibrosis |
| EP4161925A4 (en) | 2020-06-09 | 2024-09-04 | Viking Therapeutics, Inc. | COMPOSITIONS AND METHODS FOR THE TREATMENT OF LIVER DISEASES |
Family Cites Families (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE515812A (enExample) | ||||
| GB782745A (en) | 1953-08-13 | 1957-09-11 | Arthur Alfred Hellbaum | Improvements in or relating to pharmaceutical compositions |
| GB859546A (en) | 1956-05-29 | 1961-01-25 | Arthur Alfred Hellbaum | Composition for treatment of the skin |
| US3090724A (en) * | 1961-01-03 | 1963-05-21 | Baxter Laboratories Inc | Method of treating dermatological conditions |
| FR6435M (enExample) * | 1967-02-24 | 1968-11-04 | ||
| FR6656M (enExample) * | 1967-02-23 | 1969-01-27 | ||
| FR2139748B1 (enExample) | 1971-06-03 | 1974-08-30 | Theranol Lab | |
| FR2153202A1 (en) | 1971-09-24 | 1973-05-04 | Ind Chimique | Triiodothyroacetic acid salts prepn - with metals and organic bases |
| CH622703A5 (en) | 1976-06-10 | 1981-04-30 | Berema Sa | Therapeutic compositions for treating deposits of excess fat and infiltrates causing cellulite |
| FR2357246A1 (fr) | 1976-07-09 | 1978-02-03 | Martinez Gerard | Nouvelles compositions therapeutiques douees d'activite anti-inflammatoire, antalgique et anti-cellulitique |
| CH642851A5 (en) | 1980-02-13 | 1984-05-15 | Berema Sa | Medicinal compositions for the treatment of cellulite |
| FR2501505A1 (fr) | 1981-03-11 | 1982-09-17 | Ana Laboratoires | Nouveaux medicaments destines au traitement des hyperlipidemies et hypercholesterolemies a base d'acide 3,5-diiodo-3'-isopropyl-thyroacetique |
| US4889847A (en) | 1986-11-03 | 1989-12-26 | Ortho Pharmaceutical Corporation | Prevention of glucocorticoid-induced skin atrophy |
| US5019569A (en) | 1986-11-03 | 1991-05-28 | Ortho Pharmaceutical Corporation | Reversal of glucocorticoid-induced skin atrophy |
| US5118707A (en) | 1990-10-31 | 1992-06-02 | The Procter & Gamble Company | Compositions for regulating skin wrinkles comprising a benzofuran derivative |
| HUT67319A (en) * | 1991-08-30 | 1995-03-28 | Life Medical Sciences Inc | Compositions for treating wounds |
| US5591709A (en) * | 1991-08-30 | 1997-01-07 | Life Medical Sciences, Inc. | Compositions and methods for treating wounds |
| EP0614353A1 (en) | 1991-11-25 | 1994-09-14 | Richardson-Vicks, Inc. | Compositions for regulating skin wrinkles and/or skin atrophy |
| US5284971A (en) | 1992-07-16 | 1994-02-08 | Syntex (U.S.A.) Inc. | 4-(3-cyclohexyl-4-hydroxy or-methoxy phenylsulfonyl) 3,5 dibromo phenyl acetic thyromimetic cholesterol-lowering agents |
| US6221911B1 (en) * | 1995-06-07 | 2001-04-24 | Karo Bio Ab | Uses for thyroid hormone compounds or thyroid hormone-like compounds |
| JPH11508241A (ja) * | 1995-06-07 | 1999-07-21 | カロ バイオ エービー | 甲状腺ホルモンまたは甲状腺ホルモン様化合物に関する新規な使用 |
| US5951989A (en) * | 1997-04-07 | 1999-09-14 | Heymann; Warren R. | Method for the treatment of dry skin |
| GB9713739D0 (en) * | 1997-06-27 | 1997-09-03 | Karobio Ab | Thyroid receptor ligands |
-
2000
- 2000-07-14 US US09/617,052 patent/US6380255B1/en not_active Expired - Lifetime
-
2001
- 2001-07-16 AU AU2001270831A patent/AU2001270831A1/en not_active Abandoned
- 2001-07-16 CA CA002415285A patent/CA2415285A1/en not_active Abandoned
- 2001-07-16 EP EP01949712A patent/EP1328265A2/en not_active Withdrawn
- 2001-07-16 JP JP2002511766A patent/JP2004519418A/ja active Pending
- 2001-07-16 WO PCT/GB2001/003182 patent/WO2002005834A2/en not_active Ceased
-
2002
- 2002-02-25 US US10/081,397 patent/US20020123521A1/en not_active Abandoned
-
2012
- 2012-03-06 JP JP2012049349A patent/JP2012144544A/ja active Pending
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