|
US4434228A
(en)
*
|
1982-04-20 |
1984-02-28 |
Genex Corporation |
Immobilization of biological materials in condensed polyalkyleneimine polymers
|
|
DE3486053T3
(de)
|
1983-10-20 |
2004-01-08 |
The Research Foundation Of State University Of New York |
Regulierung von Gen-Expression durch Translationshemmung unter Verwendung von m-RNS hinderndem Komplementär-RNS.
|
|
FR2573436B1
(fr)
|
1984-11-20 |
1989-02-17 |
Pasteur Institut |
Adn recombinant comportant une sequence nucleotidique codant pour un polypeptide determine sous le controle d'un promoteur d'adenovirus, vecteurs contenant cet adn recombinant, cellules eucaryotes transformees par cet adn recombinant, produits d'excretion de ces cellules transformees et leurs applications, notamment a la constitution de vaccins
|
|
US4816568A
(en)
*
|
1986-05-16 |
1989-03-28 |
International Minerals & Chemical Corp. |
Stabilization of growth hormones
|
|
FR2602790B1
(fr)
|
1986-08-13 |
1990-06-01 |
Transgene Sa |
Expression d'un antigene specifique de tumeur par un virus vecteur recombinant et utilisation de celui-ci pour le traitement preventif ou curatif de la tumeur correspondante
|
|
ATE115999T1
(de)
|
1987-12-15 |
1995-01-15 |
Gene Shears Pty Ltd |
Ribozyme.
|
|
US5252713A
(en)
*
|
1988-09-23 |
1993-10-12 |
Neorx Corporation |
Polymeric carriers for non-covalent drug conjugation
|
|
US5420105A
(en)
*
|
1988-09-23 |
1995-05-30 |
Gustavson; Linda M. |
Polymeric carriers for non-covalent drug conjugation
|
|
US5744166A
(en)
*
|
1989-02-25 |
1998-04-28 |
Danbiosyst Uk Limited |
Drug delivery compositions
|
|
US5670617A
(en)
*
|
1989-12-21 |
1997-09-23 |
Biogen Inc |
Nucleic acid conjugates of tat-derived transport polypeptides
|
|
US5804604A
(en)
*
|
1989-12-21 |
1998-09-08 |
Biogen, Inc. |
Tat-derived transport polypeptides and fusion proteins
|
|
US5629020A
(en)
*
|
1994-04-22 |
1997-05-13 |
Emisphere Technologies, Inc. |
Modified amino acids for drug delivery
|
|
EP0554284B1
(en)
|
1990-10-24 |
1996-12-18 |
Allelix Biopharmaceuticals Inc. |
Peptide-based inhibitors of hiv replication
|
|
US5190873A
(en)
*
|
1991-06-21 |
1993-03-02 |
California Institute Of Biological Research |
Hybrid tryptophan aporepressor containing ligand binding sites
|
|
GB9120306D0
(en)
*
|
1991-09-24 |
1991-11-06 |
Graham Herbert K |
Method and compositions for the treatment of cerebral palsy
|
|
US5607691A
(en)
*
|
1992-06-12 |
1997-03-04 |
Affymax Technologies N.V. |
Compositions and methods for enhanced drug delivery
|
|
CA2135642C
(en)
|
1992-08-21 |
1999-12-14 |
James G. Barsoum |
Tat-derived transport polypeptides
|
|
US5877278A
(en)
|
1992-09-24 |
1999-03-02 |
Chiron Corporation |
Synthesis of N-substituted oligomers
|
|
US5709861A
(en)
*
|
1993-04-22 |
1998-01-20 |
Emisphere Technologies, Inc. |
Compositions for the delivery of antigens
|
|
US6974578B1
(en)
*
|
1993-12-28 |
2005-12-13 |
Allergan, Inc. |
Method for treating secretions and glands using botulinum toxin
|
|
US5766605A
(en)
*
|
1994-04-15 |
1998-06-16 |
Mount Sinai School Of Medicine Of The City University Of New York |
Treatment of autonomic nerve dysfunction with botulinum toxin
|
|
US5484720A
(en)
*
|
1994-09-08 |
1996-01-16 |
Genentech, Inc. |
Methods for calcium phosphate transfection
|
|
NO180167C
(no)
*
|
1994-09-08 |
1997-02-26 |
Photocure As |
Fotokjemisk fremgangsmåte til å innföre molekyler i cellers cytosol
|
|
US6232295B1
(en)
*
|
1994-10-12 |
2001-05-15 |
Jon Faiz Kayyem |
Cell-specific contrast agent and gene delivery vehicles
|
|
US5512547A
(en)
*
|
1994-10-13 |
1996-04-30 |
Wisconsin Alumni Research Foundation |
Pharmaceutical composition of botulinum neurotoxin and method of preparation
|
|
US5756468A
(en)
*
|
1994-10-13 |
1998-05-26 |
Wisconsin Alumni Research Foundation |
Pharmaceutical compositions of botulinum toxin or botulinum neurotoxin and methods of preparation
|
|
US5795587A
(en)
*
|
1995-01-23 |
1998-08-18 |
University Of Pittsburgh |
Stable lipid-comprising drug delivery complexes and methods for their production
|
|
GB9508204D0
(en)
*
|
1995-04-21 |
1995-06-07 |
Speywood Lab Ltd |
A novel agent able to modify peripheral afferent function
|
|
GB9600272D0
(en)
*
|
1996-01-06 |
1996-03-06 |
Univ Nottingham |
Polymers
|
|
AU729643B2
(en)
|
1996-05-01 |
2001-02-08 |
Antivirals Inc. |
Polypeptide conjugates for transporting substances across cell membranes
|
|
GB9623051D0
(en)
|
1996-11-06 |
1997-01-08 |
Schacht Etienne H |
Delivery of DNA to target cells in biological systems
|
|
FR2755976B1
(fr)
*
|
1996-11-15 |
1999-01-15 |
Idm Immuno Designed Molecules |
Nouveaux complexes d'acides nucleiques et de polymere substitue par des residus entrainant la destabilisation des membranes cellulaires
|
|
US5794496A
(en)
|
1996-12-05 |
1998-08-18 |
Hand Tool Design Corporation |
Pawl module for ratchet wrench
|
|
JP2002515932A
(ja)
*
|
1997-04-18 |
2002-05-28 |
カリフォルニア インスティチュート オブ テクノロジー |
多機能性ポリマー性組織コーティング
|
|
IL132941A0
(en)
*
|
1997-05-21 |
2001-03-19 |
Univ Leland Stanford Junior |
Composition and method for enhancing transport across biological membranes
|
|
EP1030927A1
(en)
*
|
1997-11-12 |
2000-08-30 |
Valentis Inc. |
Expression plasmids for multiepitope nucleic acid-based vaccines
|
|
US5985434A
(en)
*
|
1997-11-25 |
1999-11-16 |
Kimberly-Clark Worldwide, Inc. |
Absorbent foam
|
|
CA2314267A1
(en)
*
|
1997-12-10 |
1999-06-17 |
Washington University |
Anti-pathogen system and methods of use thereof
|
|
WO1999042091A2
(en)
*
|
1998-02-19 |
1999-08-26 |
Massachusetts Institute Of Technology |
Use of polycations as endosomolytic agents
|
|
US6011646A
(en)
|
1998-02-20 |
2000-01-04 |
The Regents Of The Unviersity Of California |
Method to adjust multilayer film stress induced deformation of optics
|
|
FR2777890B1
(fr)
*
|
1998-04-22 |
2000-12-29 |
Roussy Inst Gustave |
Composes peptidiques d'hsp70 utiles dans l'immunotherapie du cancer
|
|
US6261679B1
(en)
*
|
1998-05-22 |
2001-07-17 |
Kimberly-Clark Worldwide, Inc. |
Fibrous absorbent material and methods of making the same
|
|
TR200100254T2
(tr)
*
|
1998-07-13 |
2001-06-21 |
Expression Genetics, Inc. |
Eriyebilir ve bakterilerle ayrışabilir bir gen iletim taşıyıcısı olarak poly-l-lysine benzeri bir poliyester.
|
|
US6280937B1
(en)
*
|
1998-08-14 |
2001-08-28 |
Rigel Pharmaceuticals, Inc. |
Shuttle vectors
|
|
EP1128844B1
(en)
|
1998-10-27 |
2006-01-04 |
Mayo Foundation For Medical Education And Research |
Botulinum toxins for enhancing wound healing
|
|
WO2000032764A1
(en)
*
|
1998-12-02 |
2000-06-08 |
I.D.M. Immuno-Designed Molecules |
New oligomeric conjugates liable to transfer biological molecules into cells
|
|
JP2002531113A
(ja)
|
1998-12-10 |
2002-09-24 |
ワシントン大学 |
蛋白質の形質導入システムおよびその使用法
|
|
EP1159418A2
(en)
*
|
1998-12-11 |
2001-12-05 |
Biomira Inc. |
Muc-1 antagonists and methods of treating immune disorders
|
|
US7056656B1
(en)
*
|
1999-01-25 |
2006-06-06 |
University Of Medicine And Dentistry Of New Jersey |
Tat-derived oligourea and its method of production and use in high affinity and specific binding HIV-1 TAR RNA
|
|
ES2160485B1
(es)
|
1999-04-23 |
2002-05-16 |
Lipotec Sa |
Peptidos inhibidores de la exocitosis neuronal, composiciones cosmeticas y farmaceuticas que los contienen.
|
|
US20030236214A1
(en)
*
|
1999-06-09 |
2003-12-25 |
Wolff Jon A. |
Charge reversal of polyion complexes and treatment of peripheral occlusive disease
|
|
EP1074625A3
(en)
*
|
1999-06-14 |
2002-01-02 |
Pfizer Products Inc. |
DNA vaccine against feline immunodeficiency virus
|
|
US6492152B1
(en)
*
|
1999-06-15 |
2002-12-10 |
The Board Of Regents Of The University Of Oklahoma |
Core 1 β3-galactosyl transferases and methods of use thereof
|
|
US7008924B1
(en)
*
|
1999-07-21 |
2006-03-07 |
Amgen, Inc. |
VGF fusion polypeptides
|
|
US6730293B1
(en)
*
|
1999-08-24 |
2004-05-04 |
Cellgate, Inc. |
Compositions and methods for treating inflammatory diseases of the skin
|
|
US6669951B2
(en)
*
|
1999-08-24 |
2003-12-30 |
Cellgate, Inc. |
Compositions and methods for enhancing drug delivery across and into epithelial tissues
|
|
CA2381425A1
(en)
*
|
1999-08-24 |
2001-03-01 |
Cellgate, Inc. |
Enhancing drug delivery across and into epithelial tissues using oligo arginine moieties
|
|
US7229961B2
(en)
*
|
1999-08-24 |
2007-06-12 |
Cellgate, Inc. |
Compositions and methods for enhancing drug delivery across and into ocular tissues
|
|
US20030104622A1
(en)
*
|
1999-09-01 |
2003-06-05 |
Robbins Paul D. |
Identification of peptides that facilitate uptake and cytoplasmic and/or nuclear transport of proteins, DNA and viruses
|
|
CA2383743A1
(en)
*
|
1999-09-03 |
2001-03-15 |
The University Of Iowa Research Foundation |
Quorum sensing signaling in bacteria
|
|
US6610820B1
(en)
*
|
1999-10-12 |
2003-08-26 |
University Of Lausanne |
Cell-permeable peptide inhibitors of the JNK signal transduction pathway
|
|
US6297056B1
(en)
*
|
1999-10-12 |
2001-10-02 |
Pioneer Hi-Bred International, Inc. |
Brassica transformation via microprojectile bombardment
|
|
US6511676B1
(en)
*
|
1999-11-05 |
2003-01-28 |
Teni Boulikas |
Therapy for human cancers using cisplatin and other drugs or genes encapsulated into liposomes
|
|
US6844324B1
(en)
*
|
1999-11-12 |
2005-01-18 |
Massachusetts Institute Of Technology |
Modular peptide mediated intracellular delivery system and uses therefore
|
|
US7070807B2
(en)
*
|
1999-12-29 |
2006-07-04 |
Mixson A James |
Branched histidine copolymers and methods for using same
|
|
US7780967B2
(en)
*
|
2000-02-08 |
2010-08-24 |
Allergan, Inc. |
Reduced toxicity Clostridial toxin pharmaceutical compositions
|
|
US20030118598A1
(en)
*
|
2000-02-08 |
2003-06-26 |
Allergan, Inc. |
Clostridial toxin pharmaceutical compositions
|
|
US20020009491A1
(en)
|
2000-02-14 |
2002-01-24 |
Rothbard Jonathan B. |
Compositions and methods for enhancing drug delivery across biological membranes and tissues
|
|
US6670322B2
(en)
*
|
2000-06-01 |
2003-12-30 |
Wisconsin Alumni Research Foundation |
Method of targeting pharmaceuticals to motor neurons
|
|
US20040033241A1
(en)
*
|
2000-06-02 |
2004-02-19 |
Allergan, Inc. |
Controlled release botulinum toxin system
|
|
US6306423B1
(en)
*
|
2000-06-02 |
2001-10-23 |
Allergan Sales, Inc. |
Neurotoxin implant
|
|
ES2277820T3
(es)
*
|
2000-06-14 |
2007-08-01 |
Eads Astrium Sas |
Procedimiento y sistema de video a peticion.
|
|
EP1301213B1
(en)
|
2000-07-21 |
2017-01-18 |
ReVance Therapeutics, Inc. |
Multi-component biological transport systems
|
|
US7491799B2
(en)
*
|
2000-07-21 |
2009-02-17 |
Allergan, Inc. |
Modified botulinum neurotoxins
|
|
US20040220100A1
(en)
*
|
2000-07-21 |
2004-11-04 |
Essentia Biosystems, Inc. |
Multi-component biological transport systems
|
|
US6696038B1
(en)
*
|
2000-09-14 |
2004-02-24 |
Expression Genetics, Inc. |
Cationic lipopolymer as biocompatible gene delivery agent
|
|
US6831059B2
(en)
*
|
2000-10-20 |
2004-12-14 |
Allergan, Inc. |
Compositions and methods for treating gonadotrophin related illnesses
|
|
MXPA03007358A
(es)
|
2001-02-16 |
2004-12-13 |
Cellgate Inc |
Transportadores que contienen porciones de arginina separadas.
|
|
US20030086256A1
(en)
|
2001-11-02 |
2003-05-08 |
Heart Linked Corporation Ltd |
Compact light weight energy-efficient illumination module for integrated portable applications
|
|
US7060498B1
(en)
*
|
2001-11-28 |
2006-06-13 |
Genta Salus Llc |
Polycationic water soluble copolymer and method for transferring polyanionic macromolecules across biological barriers
|
|
AU2002359679B2
(en)
*
|
2001-12-11 |
2009-01-08 |
Cellgate, Inc. |
Guanidinium transport reagents and conjugates
|
|
EP1572941A4
(en)
*
|
2002-02-26 |
2009-03-18 |
Maxygen Inc |
NEW FLAVIVIRUS ANTIGENES
|
|
US20030215395A1
(en)
*
|
2002-05-14 |
2003-11-20 |
Lei Yu |
Controllably degradable polymeric biomolecule or drug carrier and method of synthesizing said carrier
|
|
US7459164B2
(en)
*
|
2002-05-28 |
2008-12-02 |
Botulinum Toxin Research Associates, Inc. |
Composition for therapeutic and cosmetic botulinum toxin
|
|
AU2003237346A1
(en)
*
|
2002-05-31 |
2003-12-19 |
Thomas Jefferson University |
Compositions and methods for transepithelial molecular transport
|
|
US20040009180A1
(en)
*
|
2002-07-11 |
2004-01-15 |
Allergan, Inc. |
Transdermal botulinum toxin compositions
|
|
US7071167B2
(en)
*
|
2002-11-13 |
2006-07-04 |
L'oreal |
Use of a combination of components with an inhibitory synergistic effect on calcium channels to prevent or treat wrinkles and fine lines
|
|
US6866856B2
(en)
*
|
2002-12-31 |
2005-03-15 |
Avon Products, Inc. |
Compositions and delivery methods for the treatment of wrinkles, fine lines and hyperhidrosis
|
|
WO2004084805A2
(en)
*
|
2003-03-19 |
2004-10-07 |
The J. David Gladstone Institutes |
Acetylated tat polypeptides and methods of use thereof
|
|
US20040192754A1
(en)
*
|
2003-03-24 |
2004-09-30 |
Shapira Nathan Andrew |
Methods for treating idiopathic hyperhidrosis and associated conditions
|
|
US20040247623A1
(en)
*
|
2003-03-24 |
2004-12-09 |
Roger Cady |
Method and article for treatment of sensory neuron related disorders through transdermal application of botulinum toxin
|
|
CN1946431B
(zh)
*
|
2004-03-03 |
2011-12-07 |
雷文斯治疗公司 |
用于肉毒毒素的局部施用和透皮递送的组合物和方法
|
|
CA2558676C
(en)
*
|
2004-03-03 |
2019-04-16 |
Essentia Biosystems, Inc. |
Compositions and methods for topical diagnostic and therapeutic transport
|
|
US7691381B2
(en)
*
|
2004-04-15 |
2010-04-06 |
Allergan, Inc. |
Stabilized biodegradable neurotoxin implants
|
|
US20060040882A1
(en)
*
|
2004-05-04 |
2006-02-23 |
Lishan Chen |
Compostions and methods for enhancing delivery of nucleic acids into cells and for modifying expression of target genes in cells
|
|
BRPI0513850A
(pt)
*
|
2004-07-26 |
2008-05-20 |
Merz Pharma Gmbh & Co Kgaa |
composição terapêutica com uma neurotoxina botulìnica
|
|
US20060024331A1
(en)
*
|
2004-08-02 |
2006-02-02 |
Ester Fernandez-Salas |
Toxin compounds with enhanced membrane translocation characteristics
|
|
SG160357A1
(en)
*
|
2005-03-03 |
2010-04-29 |
Revance Therapeutics Inc |
Compositions and methods for topical application and transdermal delivery of botulinum toxins
|