MX370929B - Composiciones y usos de las mismas para el tratamiento seguro de la rinitis. - Google Patents
Composiciones y usos de las mismas para el tratamiento seguro de la rinitis.Info
- Publication number
- MX370929B MX370929B MX2015005417A MX2015005417A MX370929B MX 370929 B MX370929 B MX 370929B MX 2015005417 A MX2015005417 A MX 2015005417A MX 2015005417 A MX2015005417 A MX 2015005417A MX 370929 B MX370929 B MX 370929B
- Authority
- MX
- Mexico
- Prior art keywords
- methods
- rhinitis
- compositions
- safe treatment
- botulinum neurotoxin
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
- A61K38/4886—Metalloendopeptidases (3.4.24), e.g. collagenase
- A61K38/4893—Botulinum neurotoxin (3.4.24.69)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/42—Proteins; Polypeptides; Degradation products thereof; Derivatives thereof, e.g. albumin, gelatin or zein
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0043—Nose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M31/00—Devices for introducing or retaining media, e.g. remedies, in cavities of the body
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
- C12Y304/24—Metalloendopeptidases (3.4.24)
- C12Y304/24069—Bontoxilysin (3.4.24.69), i.e. botulinum neurotoxin
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Gastroenterology & Hepatology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Inorganic Chemistry (AREA)
- Otolaryngology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Anesthesiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
Abstract
La presente invención se refiere a composiciones y usos de los mismos para tratar la rinitis en un sujeto en la presente. Las composiciones para usarse en la presente invención son composiciones tópicas para la administración intranasal que comprende una neurotoxina botulínica purificada, un portador y un modificador de viscosidad para aplicación en una o más superficies internas de la nariz. Las composiciones para usarse descritas en la presente proporcionan enfoques alternados para el suministro de la neurotoxina botulínica a la anatomía nasal para usarse en el tratamiento de la rinitis.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201261719462P | 2012-10-28 | 2012-10-28 | |
PCT/US2013/067154 WO2014066916A2 (en) | 2012-10-28 | 2013-10-28 | Compositions and methods for safe treatment of rhinitis |
Publications (2)
Publication Number | Publication Date |
---|---|
MX2015005417A MX2015005417A (es) | 2015-11-30 |
MX370929B true MX370929B (es) | 2020-01-08 |
Family
ID=50545513
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2015005417A MX370929B (es) | 2012-10-28 | 2013-10-28 | Composiciones y usos de las mismas para el tratamiento seguro de la rinitis. |
Country Status (4)
Country | Link |
---|---|
US (3) | US20140120077A1 (es) |
CA (1) | CA2889833A1 (es) |
MX (1) | MX370929B (es) |
WO (1) | WO2014066916A2 (es) |
Families Citing this family (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA3031270A1 (en) | 2004-03-03 | 2005-12-22 | Revance Therapeutics, Inc. | Compositions and methods for topical diagnostic and therapeutic transport |
US9211248B2 (en) | 2004-03-03 | 2015-12-15 | Revance Therapeutics, Inc. | Compositions and methods for topical application and transdermal delivery of botulinum toxins |
RU2007136616A (ru) * | 2005-03-03 | 2009-04-10 | Риванс Терапьютикс, Инк. (Us) | Композиция и способ для местного применения и чрескожного введения ботулинового токсина |
US8617568B2 (en) * | 2007-07-10 | 2013-12-31 | Medy-Tox, Inc. | Pharmaceutical liquid composition of botulinum toxin with improved stability |
MX366344B (es) | 2009-06-25 | 2019-07-05 | Revance Therapeutics Inc | Formulaciones de toxina botulinica libres de albumina. |
PT2490986T (pt) * | 2009-10-21 | 2018-11-13 | Revance Therapeutics Inc | Métodos e sistemas para purificar neurotoxina botulínica não complexada |
EP2512507A4 (en) * | 2009-12-15 | 2013-04-17 | Ira Sanders | TREATMENT OF NOSE AND BREAST DRESS |
RU2609289C1 (ru) * | 2015-09-21 | 2017-02-01 | Государственное бюджетное учреждение здравоохранения города Москвы "Научно исследовательский клинический институт Оториноларингологии им. Л.И. Свержевского" Департамента здравоохранения города Москвы | Способ лечения хронических ринитов селективной денервацией слизистой оболочки полости носа |
WO2017075468A1 (en) * | 2015-10-29 | 2017-05-04 | Revance Therapeutics, Inc. | Injectable botulinum toxin formulations and methods of use thereof having long duration of therapeutic or cosmetic effect |
AU2017326253B2 (en) * | 2016-09-13 | 2021-10-21 | Allergan, Inc. | Stabilized non-protein clostridial toxin compositions |
JP2019535829A (ja) * | 2016-11-21 | 2019-12-12 | エイリオン セラピューティクス, インコーポレイテッド | 大型薬剤の経皮送達 |
WO2018236873A1 (en) | 2017-06-19 | 2018-12-27 | President And Fellows Of Harvard College | METHODS AND COMPOSITIONS FOR THE TREATMENT OF MICROBIAL INFECTION |
CA3066951A1 (en) * | 2017-06-30 | 2019-01-03 | Allergan, Inc. | Dissolving film for delivery of a clostridial derivative |
US20210162026A1 (en) * | 2017-08-28 | 2021-06-03 | Revance Therapeutics, Inc. | Transmucosal botulinum toxin compositions, kits, and methods for treating bladder disorders |
WO2019113044A1 (en) * | 2017-12-07 | 2019-06-13 | Ps Therapies Ltd | Topical compositions and methods of use thereof |
WO2021113926A1 (en) * | 2019-12-13 | 2021-06-17 | Francesco Barbagallo | Botulinum toxin formulations and methods for intranasal delivery thereof for the treatment of allergic rhinitis |
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-
2013
- 2013-10-28 CA CA2889833A patent/CA2889833A1/en not_active Abandoned
- 2013-10-28 MX MX2015005417A patent/MX370929B/es active IP Right Grant
- 2013-10-28 US US14/065,379 patent/US20140120077A1/en not_active Abandoned
- 2013-10-28 WO PCT/US2013/067154 patent/WO2014066916A2/en active Application Filing
-
2016
- 2016-05-16 US US15/155,551 patent/US10201594B2/en active Active - Reinstated
-
2019
- 2019-02-11 US US16/272,998 patent/US20200345819A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
WO2014066916A2 (en) | 2014-05-01 |
US20140120077A1 (en) | 2014-05-01 |
US10201594B2 (en) | 2019-02-12 |
US20160250302A1 (en) | 2016-09-01 |
CA2889833A1 (en) | 2014-05-01 |
WO2014066916A3 (en) | 2015-07-23 |
MX2015005417A (es) | 2015-11-30 |
US20200345819A1 (en) | 2020-11-05 |
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