JP2004512045A - Abca7遺伝子を調節する核酸、その活性をモジュレートする分子および治療用途 - Google Patents

Abca7遺伝子を調節する核酸、その活性をモジュレートする分子および治療用途 Download PDF

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JP2004512045A
JP2004512045A JP2002537874A JP2002537874A JP2004512045A JP 2004512045 A JP2004512045 A JP 2004512045A JP 2002537874 A JP2002537874 A JP 2002537874A JP 2002537874 A JP2002537874 A JP 2002537874A JP 2004512045 A JP2004512045 A JP 2004512045A
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nucleic acid
abca7
transcription
polynucleotide
sequence
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JP2002537874A
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Japanese (ja)
Inventor
パトリス・デネフル
マリー−フランソワ・ロジエ
カトリン・プラデ
イザベル・アルヌール−レギン
ジョゼ・オソーリオイフォルテア
ニコーラ・デュヴェルジェ
ジョヴァンナ・シミニ
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アベンティス・ファーマ・ソシエテ・アノニム
インセルム
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Priority claimed from FR0013649A external-priority patent/FR2822165B1/fr
Application filed by アベンティス・ファーマ・ソシエテ・アノニム, インセルム filed Critical アベンティス・ファーマ・ソシエテ・アノニム
Publication of JP2004512045A publication Critical patent/JP2004512045A/ja
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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00Genetically modified animals
    • A01K2217/05Animals comprising random inserted nucleic acids (transgenic)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2830/00Vector systems having a special element relevant for transcription
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2830/00Vector systems having a special element relevant for transcription
    • C12N2830/80Vector systems having a special element relevant for transcription from vertebrates
    • C12N2830/85Vector systems having a special element relevant for transcription from vertebrates mammalian

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Zoology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Wood Science & Technology (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Plant Pathology (AREA)
  • Pain & Pain Management (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Rheumatology (AREA)
  • Physics & Mathematics (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
JP2002537874A 2000-10-24 2001-10-17 Abca7遺伝子を調節する核酸、その活性をモジュレートする分子および治療用途 Pending JP2004512045A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR0013649A FR2822165B1 (fr) 2000-10-24 2000-10-24 Acide nucleique regulateur du gene abca7, molecules modulant son activite et applications therapeutiques
US25314100P 2000-11-28 2000-11-28
PCT/FR2001/003219 WO2002034903A2 (fr) 2000-10-24 2001-10-17 Acide nucleique regulateur du gene abca7, molecules modulant son activite et applications therapeutiques

Publications (1)

Publication Number Publication Date
JP2004512045A true JP2004512045A (ja) 2004-04-22

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ID=26212696

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2002537874A Pending JP2004512045A (ja) 2000-10-24 2001-10-17 Abca7遺伝子を調節する核酸、その活性をモジュレートする分子および治療用途

Country Status (5)

Country Link
EP (1) EP1334186A2 (fr)
JP (1) JP2004512045A (fr)
AU (1) AU2002210661A1 (fr)
CA (1) CA2426294A1 (fr)
WO (1) WO2002034903A2 (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20070026408A1 (en) * 2003-12-15 2007-02-01 Noab Biodisccoveries Inc. Materials and methods for analysis of atp-binding cassette transporter gene expression

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2004507202A (ja) * 1999-03-31 2004-03-11 キュラジェン コーポレイション ポリペプチドをコードするオープンリーディングフレームを含む核酸;「orfx」
FR2796808B1 (fr) * 1999-07-30 2004-03-12 Inst Nat Sante Rech Med Nouvelles applications des transporteurs de type abca

Also Published As

Publication number Publication date
EP1334186A2 (fr) 2003-08-13
CA2426294A1 (fr) 2002-05-02
WO2002034903A2 (fr) 2002-05-02
WO2002034903A3 (fr) 2002-08-08
AU2002210661A1 (en) 2002-05-06

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