JP2004506606A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2004506606A5 JP2004506606A5 JP2001580925A JP2001580925A JP2004506606A5 JP 2004506606 A5 JP2004506606 A5 JP 2004506606A5 JP 2001580925 A JP2001580925 A JP 2001580925A JP 2001580925 A JP2001580925 A JP 2001580925A JP 2004506606 A5 JP2004506606 A5 JP 2004506606A5
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- group
- dihydrofuro
- ribofuranosyl
- deoxy
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0009486.2A GB0009486D0 (en) | 2000-04-17 | 2000-04-17 | Chemical compounds |
| GB0009486.2 | 2000-04-17 | ||
| PCT/GB2001/001694 WO2001083501A1 (en) | 2000-04-17 | 2001-04-12 | Anti-viral pyrimidine nucleoside analogues |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2004506606A JP2004506606A (ja) | 2004-03-04 |
| JP2004506606A5 true JP2004506606A5 (enExample) | 2008-04-24 |
| JP4959900B2 JP4959900B2 (ja) | 2012-06-27 |
Family
ID=9890100
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2001580925A Expired - Fee Related JP4959900B2 (ja) | 2000-04-17 | 2001-04-12 | 抗ウイルスピリミジンヌクレオシド類 |
Country Status (14)
| Country | Link |
|---|---|
| US (4) | US7820631B2 (enExample) |
| EP (1) | EP1274713B1 (enExample) |
| JP (1) | JP4959900B2 (enExample) |
| AT (1) | ATE261451T1 (enExample) |
| AU (1) | AU781323B2 (enExample) |
| CA (1) | CA2403835C (enExample) |
| DE (1) | DE60102293T2 (enExample) |
| DK (1) | DK1274713T3 (enExample) |
| ES (1) | ES2215931T3 (enExample) |
| GB (1) | GB0009486D0 (enExample) |
| NZ (1) | NZ521828A (enExample) |
| PT (1) | PT1274713E (enExample) |
| TR (1) | TR200400785T4 (enExample) |
| WO (1) | WO2001083501A1 (enExample) |
Families Citing this family (33)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL137164A0 (en) | 1998-01-23 | 2001-07-24 | Newbiotics Inc | Enzyme catalyzed therapeutic agents |
| US7462605B2 (en) | 1998-01-23 | 2008-12-09 | Celmed Oncology (Usa), Inc. | Phosphoramidate compounds and methods of use |
| US6683061B1 (en) | 1999-07-22 | 2004-01-27 | Newbiotics, Inc. | Enzyme catalyzed therapeutic activation |
| BR0012676A (pt) | 1999-07-22 | 2003-07-01 | Newbiotics Inc | Métodos para tratamento de tumores resistentes a terapia |
| GB0009486D0 (en) * | 2000-04-17 | 2000-06-07 | Univ Cardiff | Chemical compounds |
| MY164523A (en) | 2000-05-23 | 2017-12-29 | Univ Degli Studi Cagliari | Methods and compositions for treating hepatitis c virus |
| LT1576138T (lt) | 2002-11-15 | 2017-06-26 | Idenix Pharmaceuticals Llc | 2`-šakoti nukleozidai derinyje su interferonu ir flaviviridae mutacija |
| GB0609178D0 (en) | 2006-05-09 | 2006-06-21 | Univ Cardiff | Novel compounds |
| WO2008104893A2 (en) | 2007-02-28 | 2008-09-04 | The Governors Of The University Of Alberta | Compounds for preventing or treating viral infections and methods of use thereof |
| GB2452556A (en) * | 2007-09-07 | 2009-03-11 | Univ Leuven Kath | Nucleoside analogues esterified at 3 and/or 5 positions by neutral non-polar amino acid, or oligopeptide thereof, for combating Varicella Zoster virus |
| GB201016855D0 (en) * | 2010-10-06 | 2010-11-17 | Nucana Biomed Ltd | Chemical compounds |
| CN102443032B (zh) * | 2010-10-09 | 2015-07-22 | 英希比泰克斯公司 | 制备抗病毒组合物的方法及其中间体的应用 |
| US9260469B2 (en) | 2010-10-09 | 2016-02-16 | Contravir Pharmaceuticals, Inc. | Method of preparation of antiviral compounds and useful intermediates thereof |
| US9243025B2 (en) | 2011-03-31 | 2016-01-26 | Idenix Pharmaceuticals, Llc | Compounds and pharmaceutical compositions for the treatment of viral infections |
| GB201111779D0 (en) | 2011-07-08 | 2011-08-24 | Univ Cardiff | Chemical compounds |
| AR088441A1 (es) | 2011-09-12 | 2014-06-11 | Idenix Pharmaceuticals Inc | Compuestos de carboniloximetilfosforamidato sustituido y composiciones farmaceuticas para el tratamiento de infecciones virales |
| US8507460B2 (en) | 2011-10-14 | 2013-08-13 | Idenix Pharmaceuticals, Inc. | Substituted 3′,5′-cyclic phosphates of purine nucleotide compounds and pharmaceutical compositions for the treatment of viral infections |
| US9296778B2 (en) | 2012-05-22 | 2016-03-29 | Idenix Pharmaceuticals, Inc. | 3′,5′-cyclic phosphate prodrugs for HCV infection |
| WO2013177188A1 (en) | 2012-05-22 | 2013-11-28 | Idenix Pharmaceuticals, Inc. | 3',5'-cyclic phosphoramidate prodrugs for hcv infection |
| JP6165848B2 (ja) | 2012-05-22 | 2017-07-19 | イデニク ファーマシューティカルズ エルエルシー | 肝疾患のためのｄ−アミノ酸化合物 |
| MX2014014323A (es) | 2012-05-25 | 2015-02-12 | Janssen R & D Ireland | Nucleosidos de espirooxetano de uracilo. |
| WO2014052638A1 (en) | 2012-09-27 | 2014-04-03 | Idenix Pharmaceuticals, Inc. | Esters and malonates of sate prodrugs |
| EP2906579B1 (en) | 2012-10-08 | 2018-04-18 | Idenix Pharmaceuticals LLC. | 2'-chloro nucleoside analogs for hcv infection |
| US10723754B2 (en) | 2012-10-22 | 2020-07-28 | Idenix Pharmaceuticals Llc | 2′,4′-bridged nucleosides for HCV infection |
| EP2935304A1 (en) | 2012-12-19 | 2015-10-28 | IDENIX Pharmaceuticals, Inc. | 4'-fluoro nucleosides for the treatment of hcv |
| WO2014137926A1 (en) | 2013-03-04 | 2014-09-12 | Idenix Pharmaceuticals, Inc. | 3'-deoxy nucleosides for the treatment of hcv |
| WO2014137930A1 (en) | 2013-03-04 | 2014-09-12 | Idenix Pharmaceuticals, Inc. | Thiophosphate nucleosides for the treatment of hcv |
| WO2014160484A1 (en) | 2013-03-13 | 2014-10-02 | Idenix Pharmaceuticals, Inc. | Amino acid phosphoramidate pronucleotides of 2'-cyano, azido and amino nucleosides for the treatment of hcv |
| EP2981542B1 (en) | 2013-04-01 | 2021-09-15 | Idenix Pharmaceuticals LLC | 2',4'-fluoro nucleosides for the treatment of hcv |
| US10005779B2 (en) | 2013-06-05 | 2018-06-26 | Idenix Pharmaceuticals Llc | 1′,4′-thio nucleosides for the treatment of HCV |
| WO2015017713A1 (en) | 2013-08-01 | 2015-02-05 | Idenix Pharmaceuticals, Inc. | D-amino acid phosphoramidate pronucleotides of halogeno pyrimidine compounds for liver disease |
| US10202411B2 (en) | 2014-04-16 | 2019-02-12 | Idenix Pharmaceuticals Llc | 3′-substituted methyl or alkynyl nucleosides nucleotides for the treatment of HCV |
| WO2018035429A1 (en) | 2016-08-18 | 2018-02-22 | Wisconsin Alumni Research Foundation | Peptides that inhibit syndecan-1 activation of vla-4 and igf-1r |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS62255499A (ja) | 1986-04-28 | 1987-11-07 | Teijin Ltd | 螢光性ヌクレオシド又はヌクレオチド |
| EP0346108A3 (en) | 1988-06-09 | 1991-04-24 | The Wellcome Foundation Limited | Anti-infective nucleosides |
| YU43193A (sh) | 1992-06-22 | 1997-01-08 | Eli Lilly And Company | 2'-deoksi-2',2'-difluoro(4-supstituisani)pirimidinski nukleozidi antivirusnog i antikancerogenog dejstva i međuproizvodi |
| GB9505025D0 (en) * | 1995-03-13 | 1995-05-03 | Medical Res Council | Chemical compounds |
| US6022876A (en) | 1996-11-15 | 2000-02-08 | Yale University | L-β-dioxolane uridine analogs and methods for treating and preventing Epstein-Barr virus infections |
| GB9708611D0 (en) | 1997-04-28 | 1997-06-18 | Univ Cardiff | Chemical compounds |
| GB9716231D0 (en) | 1997-07-31 | 1997-10-08 | Amersham Int Ltd | Base analogues |
| BR0012676A (pt) | 1999-07-22 | 2003-07-01 | Newbiotics Inc | Métodos para tratamento de tumores resistentes a terapia |
| HK1053126A1 (zh) | 1999-07-22 | 2003-10-10 | 新生物生物公司 | 酶催化的治疗活化 |
| MXPA02000761A (es) | 1999-07-22 | 2002-08-12 | Newbiotics Inc | Agentes terapeuticos anti-infecciosos catalizados por enzima. |
| GB0009486D0 (en) | 2000-04-17 | 2000-06-07 | Univ Cardiff | Chemical compounds |
| GB0011203D0 (en) | 2000-05-09 | 2000-06-28 | Univ Cardiff | Chemical compounds |
| CA2566541C (en) | 2004-06-07 | 2012-10-09 | Anadys Pharmaceuticals, Inc. | 3-.beta.-d-ribofuranosylthiazolo[4,5-d]pyrimidine nucleosides and uses thereof |
| GB0609178D0 (en) * | 2006-05-09 | 2006-06-21 | Univ Cardiff | Novel compounds |
| GB2452556A (en) * | 2007-09-07 | 2009-03-11 | Univ Leuven Kath | Nucleoside analogues esterified at 3 and/or 5 positions by neutral non-polar amino acid, or oligopeptide thereof, for combating Varicella Zoster virus |
| GB201111779D0 (en) * | 2011-07-08 | 2011-08-24 | Univ Cardiff | Chemical compounds |
-
2000
- 2000-04-17 GB GBGB0009486.2A patent/GB0009486D0/en not_active Ceased
-
2001
- 2001-04-12 WO PCT/GB2001/001694 patent/WO2001083501A1/en not_active Ceased
- 2001-04-12 DE DE60102293T patent/DE60102293T2/de not_active Expired - Lifetime
- 2001-04-12 DK DK01973778T patent/DK1274713T3/da active
- 2001-04-12 CA CA002403835A patent/CA2403835C/en not_active Expired - Fee Related
- 2001-04-12 ES ES01973778T patent/ES2215931T3/es not_active Expired - Lifetime
- 2001-04-12 PT PT01973778T patent/PT1274713E/pt unknown
- 2001-04-12 NZ NZ521828A patent/NZ521828A/en not_active IP Right Cessation
- 2001-04-12 AU AU95191/01A patent/AU781323B2/en not_active Ceased
- 2001-04-12 US US10/257,855 patent/US7820631B2/en not_active Expired - Fee Related
- 2001-04-12 JP JP2001580925A patent/JP4959900B2/ja not_active Expired - Fee Related
- 2001-04-12 AT AT01973778T patent/ATE261451T1/de active
- 2001-04-12 TR TR2004/00785T patent/TR200400785T4/xx unknown
- 2001-04-12 EP EP01973778A patent/EP1274713B1/en not_active Expired - Lifetime
-
2010
- 2010-09-24 US US12/889,980 patent/US8551965B2/en not_active Expired - Fee Related
-
2013
- 2013-09-09 US US14/021,587 patent/US9351970B2/en not_active Expired - Fee Related
-
2016
- 2016-04-29 US US15/141,992 patent/US20160244476A1/en not_active Abandoned
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2004506606A5 (enExample) | ||
| CA2403835A1 (en) | Anti-viral pyrimidine nucleoside analogues | |
| JP2005508962A5 (enExample) | ||
| ATE448226T1 (de) | Aza heterocyclische derivate und ihre therapeutische verwendung | |
| JP2019094345A5 (enExample) | ||
| JP2005538100A5 (enExample) | ||
| JP2009536620A5 (enExample) | ||
| CA2558195A1 (en) | 11-hydroxy-5h-pyrrolo[2,1-c][1,4]benzodiazepin-5-one derivatives as key intermediates for the preparation of c2 substituted pyrrolobenzodiazepines | |
| JP2004516314A5 (enExample) | ||
| JP2003532735A5 (enExample) | ||
| CA2474192A1 (en) | Nicotinamide derivates useful as p38 inhibitors | |
| JP2005511531A5 (enExample) | ||
| CA2496194A1 (en) | Phenyl-substituted pyrazolopyrimidines | |
| JP2005526152A5 (enExample) | ||
| PT1460072E (pt) | Composto biciclicos heteroaromaticos como inibidores de proteina tirosina quinase | |
| JP2015143283A5 (enExample) | ||
| NZ515282A (en) | Substituted phenyl compounds with immunosuppressing activity and pharmaceutical compositions | |
| JP2007501831A5 (enExample) | ||
| JP2006524222A5 (enExample) | ||
| WO2002040486A3 (en) | METHODS OF TREATING p38 KINASE-ASSOCIATED CONDITIONS AND PYRROLOTRIAZINE COMPOUNDS USEFUL AS KINASE INHIBITORS | |
| JP2005506352A5 (enExample) | ||
| CA2530374A1 (en) | Hsp90 family protein inhibitors | |
| RU2010126050A (ru) | Антибактериальные нуклеозидные соединения | |
| WO2005084192A3 (en) | Novel 2’-c-methyl nucleoside derivatives | |
| JP2004529114A5 (enExample) |