JP2004501969A5 - - Google Patents
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- JP2004501969A5 JP2004501969A5 JP2002506727A JP2002506727A JP2004501969A5 JP 2004501969 A5 JP2004501969 A5 JP 2004501969A5 JP 2002506727 A JP2002506727 A JP 2002506727A JP 2002506727 A JP2002506727 A JP 2002506727A JP 2004501969 A5 JP2004501969 A5 JP 2004501969A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutical composition
- composition according
- epa
- precursor
- disease
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- YZXBAPSDXZZRGB-DOFZRALJSA-N arachidonic acid Chemical compound CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(O)=O YZXBAPSDXZZRGB-DOFZRALJSA-N 0.000 description 18
- 239000008194 pharmaceutical composition Substances 0.000 description 15
- JAZBEHYOTPTENJ-JLNKQSITSA-N all-cis-5,8,11,14,17-icosapentaenoic acid Chemical compound CC\C=C/C\C=C/C\C=C/C\C=C/C\C=C/CCCC(O)=O JAZBEHYOTPTENJ-JLNKQSITSA-N 0.000 description 9
- 229940114079 arachidonic acid Drugs 0.000 description 9
- 235000021342 arachidonic acid Nutrition 0.000 description 9
- 229960005135 eicosapentaenoic acid Drugs 0.000 description 9
- JAZBEHYOTPTENJ-UHFFFAOYSA-N eicosapentaenoic acid Natural products CCC=CCC=CCC=CCC=CCC=CCCCC(O)=O JAZBEHYOTPTENJ-UHFFFAOYSA-N 0.000 description 9
- 235000020673 eicosapentaenoic acid Nutrition 0.000 description 9
- 239000002243 precursor Substances 0.000 description 7
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 5
- 201000010099 disease Diseases 0.000 description 4
- HOBAELRKJCKHQD-UHFFFAOYSA-N (8Z,11Z,14Z)-8,11,14-eicosatrienoic acid Natural products CCCCCC=CCC=CCC=CCCCCCCC(O)=O HOBAELRKJCKHQD-UHFFFAOYSA-N 0.000 description 2
- 239000004480 active ingredient Substances 0.000 description 2
- HOBAELRKJCKHQD-QNEBEIHSSA-N dihomo-γ-linolenic acid Chemical compound CCCCC\C=C/C\C=C/C\C=C/CCCCCCC(O)=O HOBAELRKJCKHQD-QNEBEIHSSA-N 0.000 description 2
- 208000024827 Alzheimer disease Diseases 0.000 description 1
- 241000894006 Bacteria Species 0.000 description 1
- 208000020925 Bipolar disease Diseases 0.000 description 1
- 208000024172 Cardiovascular disease Diseases 0.000 description 1
- 206010012289 Dementia Diseases 0.000 description 1
- 208000032928 Dyslipidaemia Diseases 0.000 description 1
- 241000233866 Fungi Species 0.000 description 1
- 208000018522 Gastrointestinal disease Diseases 0.000 description 1
- 208000017170 Lipid metabolism disease Diseases 0.000 description 1
- 206010028980 Neoplasm Diseases 0.000 description 1
- 208000018737 Parkinson disease Diseases 0.000 description 1
- 208000026723 Urinary tract disease Diseases 0.000 description 1
- 208000012931 Urologic disease Diseases 0.000 description 1
- 241000700605 Viruses Species 0.000 description 1
- 208000006673 asthma Diseases 0.000 description 1
- 201000011510 cancer Diseases 0.000 description 1
- 208000015114 central nervous system disease Diseases 0.000 description 1
- 206010012601 diabetes mellitus Diseases 0.000 description 1
- 208000016097 disease of metabolism Diseases 0.000 description 1
- 239000003995 emulsifying agent Substances 0.000 description 1
- 125000004494 ethyl ester group Chemical class 0.000 description 1
- 210000004996 female reproductive system Anatomy 0.000 description 1
- 239000000796 flavoring agent Substances 0.000 description 1
- VZCCETWTMQHEPK-QNEBEIHSSA-N gamma-linolenic acid Chemical compound CCCCC\C=C/C\C=C/C\C=C/CCCCC(O)=O VZCCETWTMQHEPK-QNEBEIHSSA-N 0.000 description 1
- 208000015181 infectious disease Diseases 0.000 description 1
- 208000027866 inflammatory disease Diseases 0.000 description 1
- 210000003734 kidney Anatomy 0.000 description 1
- 208000017169 kidney disease Diseases 0.000 description 1
- 208000019423 liver disease Diseases 0.000 description 1
- 210000004995 male reproductive system Anatomy 0.000 description 1
- 208000030159 metabolic disease Diseases 0.000 description 1
- 230000000926 neurological effect Effects 0.000 description 1
- 210000000056 organ Anatomy 0.000 description 1
- 208000027232 peripheral nervous system disease Diseases 0.000 description 1
- 208000023504 respiratory system disease Diseases 0.000 description 1
- 201000000980 schizophrenia Diseases 0.000 description 1
- 150000003626 triacylglycerols Chemical class 0.000 description 1
- 208000014001 urinary system disease Diseases 0.000 description 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0016045.7A GB0016045D0 (en) | 2000-06-29 | 2000-06-29 | Therapeutic combinations of fatty acids |
| PCT/GB2001/002717 WO2002002105A1 (en) | 2000-06-29 | 2001-06-20 | Therapeutic combinations of fatty acids |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2004501969A JP2004501969A (ja) | 2004-01-22 |
| JP2004501969A5 true JP2004501969A5 (https=) | 2008-08-07 |
Family
ID=9894724
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2002506727A Pending JP2004501969A (ja) | 2000-06-29 | 2001-06-20 | 脂肪酸の治療用組合せ |
Country Status (32)
| Country | Link |
|---|---|
| US (1) | US6479544B1 (https=) |
| EP (1) | EP1296670B1 (https=) |
| JP (1) | JP2004501969A (https=) |
| KR (1) | KR20030016306A (https=) |
| CN (1) | CN100469363C (https=) |
| AT (1) | ATE315388T1 (https=) |
| AU (2) | AU2001274276B2 (https=) |
| BR (1) | BR0112073A (https=) |
| CA (1) | CA2411368C (https=) |
| CZ (1) | CZ20024173A3 (https=) |
| DE (1) | DE60116625T2 (https=) |
| DK (1) | DK1296670T3 (https=) |
| EE (1) | EE05148B1 (https=) |
| ES (1) | ES2256250T3 (https=) |
| GB (1) | GB0016045D0 (https=) |
| HR (1) | HRP20030035A2 (https=) |
| HU (1) | HUP0301107A2 (https=) |
| IL (1) | IL153458A0 (https=) |
| IS (1) | IS2226B (https=) |
| MX (1) | MXPA02012689A (https=) |
| MY (1) | MY117830A (https=) |
| NO (1) | NO329868B1 (https=) |
| NZ (1) | NZ522916A (https=) |
| PL (1) | PL359185A1 (https=) |
| PT (1) | PT1296670E (https=) |
| RU (1) | RU2276975C2 (https=) |
| SK (1) | SK287209B6 (https=) |
| TW (1) | TWI285549B (https=) |
| UA (1) | UA76108C2 (https=) |
| WO (1) | WO2002002105A1 (https=) |
| YU (1) | YU99602A (https=) |
| ZA (1) | ZA200300198B (https=) |
Families Citing this family (79)
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|---|---|---|---|---|
| GB9901809D0 (en) | 1999-01-27 | 1999-03-17 | Scarista Limited | Highly purified ethgyl epa and other epa derivatives for psychiatric and neurological disorderes |
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| JP2003048831A (ja) | 2001-08-02 | 2003-02-21 | Suntory Ltd | 脳機能の低下に起因する症状あるいは疾患の予防又は改善作用を有する組成物 |
| WO2004028470A2 (en) | 2002-09-27 | 2004-04-08 | Martek Biosciences Corporation | Prophylactic docosahexaenoic acid therapy for patients with subclinical inflammation |
| DE10254584A1 (de) * | 2002-11-22 | 2004-06-09 | HORST HEIRLER PROJEKTE für Ernährung, Medizin, Ökologie | Verwendung von mittelkettigen Triglyceriden (MCT) zur ernährungsphysiologischen Optimierung des Fettsäurenspektrums in einem diätetischen Lebensmittel für Diabetiker |
| GB0311081D0 (en) | 2003-05-14 | 2003-06-18 | Btg Internat Limted | Treatment of neurodegenerative conditions |
| FR2856304B1 (fr) * | 2003-06-20 | 2006-03-03 | Natural Product Consulting | Composition pour la prevention des infections du systeme urinaire |
| WO2005018632A1 (en) | 2003-08-18 | 2005-03-03 | Btg International Limited | Treatment of neurodegenerative conditions |
| US7875291B1 (en) | 2003-09-05 | 2011-01-25 | Glu-Pro, Inc. | Composition for managing diabetes, obesity, and hyperlipidemia and associated methods |
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| JP5967855B2 (ja) | 2005-06-30 | 2016-08-10 | サントリーホールディングス株式会社 | 日中活動量の低下および／又はうつ症状の改善作用を有する組成物 |
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| US8343753B2 (en) * | 2007-11-01 | 2013-01-01 | Wake Forest University School Of Medicine | Compositions, methods, and kits for polyunsaturated fatty acids from microalgae |
| EP2334295B1 (en) | 2008-09-02 | 2017-06-28 | Amarin Pharmaceuticals Ireland Limited | Pharmaceutical composition comprising eicosapentaenoic acid and nicotinic acid and methods of using same |
| SI2395991T1 (sl) | 2009-02-10 | 2013-12-31 | Amarin Pharmaceuticals Ireland Limited | Uporaba etil estra eikozapentaenojske kisline za zdravljenje hipertrigliceridemije |
| NZ624963A (en) | 2009-04-29 | 2016-07-29 | Amarin Pharmaceuticals Ie Ltd | Pharmaceutical compositions comprising epa and a cardiovascular agent and methods of using the same |
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| EP3318255B1 (en) | 2009-06-15 | 2021-03-10 | Amarin Pharmaceuticals Ireland Limited | Compositions and methods for treating stroke in a subject on concomitant statin therapy |
| AU2010298222B2 (en) | 2009-09-23 | 2017-01-05 | Amarin Pharmaceuticals Ireland Limited | Pharmaceutical composition comprising omega-3 fatty acid and hydroxy-derivative of a statin and methods of using same |
| US11712429B2 (en) | 2010-11-29 | 2023-08-01 | Amarin Pharmaceuticals Ireland Limited | Low eructation composition and methods for treating and/or preventing cardiovascular disease in a subject with fish allergy/hypersensitivity |
| NZ744990A (en) | 2010-11-29 | 2019-10-25 | Amarin Pharmaceuticals Ie Ltd | Low eructation composition and methods for treating and/or preventing cardiovascular disease in a subject with fish allergy/hypersensitivity |
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| US11291643B2 (en) | 2011-11-07 | 2022-04-05 | Amarin Pharmaceuticals Ireland Limited | Methods of treating hypertriglyceridemia |
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| ES2891473T3 (es) | 2012-01-06 | 2022-01-28 | Amarin Pharmaceuticals Ie Ltd | Composiciones y métodos para reducir los niveles de alta sensibilidad (hs-CRP) en un sujeto |
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| US20140187633A1 (en) | 2012-12-31 | 2014-07-03 | Amarin Pharmaceuticals Ireland Limited | Methods of treating or preventing nonalcoholic steatohepatitis and/or primary biliary cirrhosis |
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| US10966968B2 (en) | 2013-06-06 | 2021-04-06 | Amarin Pharmaceuticals Ireland Limited | Co-administration of rosiglitazone and eicosapentaenoic acid or a derivative thereof |
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| GB9901809D0 (en) | 1999-01-27 | 1999-03-17 | Scarista Limited | Highly purified ethgyl epa and other epa derivatives for psychiatric and neurological disorderes |
-
2000
- 2000-06-29 GB GBGB0016045.7A patent/GB0016045D0/en not_active Ceased
-
2001
- 2001-06-20 EE EEP200200718A patent/EE05148B1/xx not_active IP Right Cessation
- 2001-06-20 KR KR1020027017649A patent/KR20030016306A/ko not_active Ceased
- 2001-06-20 UA UA20021210705A patent/UA76108C2/uk unknown
- 2001-06-20 RU RU2002133098/15A patent/RU2276975C2/ru not_active IP Right Cessation
- 2001-06-20 PT PT01940775T patent/PT1296670E/pt unknown
- 2001-06-20 AU AU2001274276A patent/AU2001274276B2/en not_active Ceased
- 2001-06-20 DK DK01940775T patent/DK1296670T3/da active
- 2001-06-20 SK SK1816-2002A patent/SK287209B6/sk not_active IP Right Cessation
- 2001-06-20 MX MXPA02012689A patent/MXPA02012689A/es active IP Right Grant
- 2001-06-20 JP JP2002506727A patent/JP2004501969A/ja active Pending
- 2001-06-20 NZ NZ522916A patent/NZ522916A/en unknown
- 2001-06-20 HR HR20030035A patent/HRP20030035A2/hr not_active Application Discontinuation
- 2001-06-20 CN CNB01811931XA patent/CN100469363C/zh not_active Expired - Fee Related
- 2001-06-20 CZ CZ20024173A patent/CZ20024173A3/cs unknown
- 2001-06-20 PL PL01359185A patent/PL359185A1/xx not_active Application Discontinuation
- 2001-06-20 ES ES01940775T patent/ES2256250T3/es not_active Expired - Lifetime
- 2001-06-20 IL IL15345801A patent/IL153458A0/xx not_active IP Right Cessation
- 2001-06-20 WO PCT/GB2001/002717 patent/WO2002002105A1/en not_active Ceased
- 2001-06-20 DE DE60116625T patent/DE60116625T2/de not_active Expired - Lifetime
- 2001-06-20 AT AT01940775T patent/ATE315388T1/de active
- 2001-06-20 HU HU0301107A patent/HUP0301107A2/hu unknown
- 2001-06-20 BR BR0112073-5A patent/BR0112073A/pt not_active Application Discontinuation
- 2001-06-20 AU AU7427601A patent/AU7427601A/xx active Pending
- 2001-06-20 CA CA002411368A patent/CA2411368C/en not_active Expired - Fee Related
- 2001-06-20 EP EP01940775A patent/EP1296670B1/en not_active Expired - Lifetime
- 2001-06-20 YU YU99602A patent/YU99602A/sh unknown
- 2001-06-21 MY MYPI20012947A patent/MY117830A/en unknown
- 2001-06-29 TW TW090116201A patent/TWI285549B/zh not_active IP Right Cessation
- 2001-06-29 US US09/893,473 patent/US6479544B1/en not_active Expired - Lifetime
-
2002
- 2002-11-29 IS IS6644A patent/IS2226B/is unknown
- 2002-12-18 NO NO20026093A patent/NO329868B1/no not_active IP Right Cessation
-
2003
- 2003-01-08 ZA ZA200300198A patent/ZA200300198B/en unknown
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