JP2004501969A5 - - Google Patents
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- JP2004501969A5 JP2004501969A5 JP2002506727A JP2002506727A JP2004501969A5 JP 2004501969 A5 JP2004501969 A5 JP 2004501969A5 JP 2002506727 A JP2002506727 A JP 2002506727A JP 2002506727 A JP2002506727 A JP 2002506727A JP 2004501969 A5 JP2004501969 A5 JP 2004501969A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutical composition
- composition according
- epa
- precursor
- disease
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- YZXBAPSDXZZRGB-DOFZRALJSA-N arachidonic acid Chemical compound CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(O)=O YZXBAPSDXZZRGB-DOFZRALJSA-N 0.000 description 18
- 239000008194 pharmaceutical composition Substances 0.000 description 15
- JAZBEHYOTPTENJ-JLNKQSITSA-N all-cis-5,8,11,14,17-icosapentaenoic acid Chemical compound CC\C=C/C\C=C/C\C=C/C\C=C/C\C=C/CCCC(O)=O JAZBEHYOTPTENJ-JLNKQSITSA-N 0.000 description 9
- 229940114079 arachidonic acid Drugs 0.000 description 9
- 235000021342 arachidonic acid Nutrition 0.000 description 9
- 229960005135 eicosapentaenoic acid Drugs 0.000 description 9
- JAZBEHYOTPTENJ-UHFFFAOYSA-N eicosapentaenoic acid Natural products CCC=CCC=CCC=CCC=CCC=CCCCC(O)=O JAZBEHYOTPTENJ-UHFFFAOYSA-N 0.000 description 9
- 235000020673 eicosapentaenoic acid Nutrition 0.000 description 9
- 239000002243 precursor Substances 0.000 description 7
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 5
- 201000010099 disease Diseases 0.000 description 4
- HOBAELRKJCKHQD-UHFFFAOYSA-N (8Z,11Z,14Z)-8,11,14-eicosatrienoic acid Natural products CCCCCC=CCC=CCC=CCCCCCCC(O)=O HOBAELRKJCKHQD-UHFFFAOYSA-N 0.000 description 2
- 239000004480 active ingredient Substances 0.000 description 2
- HOBAELRKJCKHQD-QNEBEIHSSA-N dihomo-γ-linolenic acid Chemical compound CCCCC\C=C/C\C=C/C\C=C/CCCCCCC(O)=O HOBAELRKJCKHQD-QNEBEIHSSA-N 0.000 description 2
- 208000024827 Alzheimer disease Diseases 0.000 description 1
- 241000894006 Bacteria Species 0.000 description 1
- 208000020925 Bipolar disease Diseases 0.000 description 1
- 208000024172 Cardiovascular disease Diseases 0.000 description 1
- 206010012289 Dementia Diseases 0.000 description 1
- 208000032928 Dyslipidaemia Diseases 0.000 description 1
- 241000233866 Fungi Species 0.000 description 1
- 208000018522 Gastrointestinal disease Diseases 0.000 description 1
- 208000017170 Lipid metabolism disease Diseases 0.000 description 1
- 206010028980 Neoplasm Diseases 0.000 description 1
- 208000018737 Parkinson disease Diseases 0.000 description 1
- 208000026723 Urinary tract disease Diseases 0.000 description 1
- 208000012931 Urologic disease Diseases 0.000 description 1
- 241000700605 Viruses Species 0.000 description 1
- 208000006673 asthma Diseases 0.000 description 1
- 201000011510 cancer Diseases 0.000 description 1
- 208000015114 central nervous system disease Diseases 0.000 description 1
- 206010012601 diabetes mellitus Diseases 0.000 description 1
- 208000016097 disease of metabolism Diseases 0.000 description 1
- 239000003995 emulsifying agent Substances 0.000 description 1
- 125000004494 ethyl ester group Chemical class 0.000 description 1
- 210000004996 female reproductive system Anatomy 0.000 description 1
- 239000000796 flavoring agent Substances 0.000 description 1
- VZCCETWTMQHEPK-QNEBEIHSSA-N gamma-linolenic acid Chemical compound CCCCC\C=C/C\C=C/C\C=C/CCCCC(O)=O VZCCETWTMQHEPK-QNEBEIHSSA-N 0.000 description 1
- 208000015181 infectious disease Diseases 0.000 description 1
- 208000027866 inflammatory disease Diseases 0.000 description 1
- 210000003734 kidney Anatomy 0.000 description 1
- 208000017169 kidney disease Diseases 0.000 description 1
- 208000019423 liver disease Diseases 0.000 description 1
- 210000004995 male reproductive system Anatomy 0.000 description 1
- 208000030159 metabolic disease Diseases 0.000 description 1
- 230000000926 neurological effect Effects 0.000 description 1
- 210000000056 organ Anatomy 0.000 description 1
- 208000027232 peripheral nervous system disease Diseases 0.000 description 1
- 208000023504 respiratory system disease Diseases 0.000 description 1
- 201000000980 schizophrenia Diseases 0.000 description 1
- 150000003626 triacylglycerols Chemical class 0.000 description 1
- 208000014001 urinary system disease Diseases 0.000 description 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0016045.7A GB0016045D0 (en) | 2000-06-29 | 2000-06-29 | Therapeutic combinations of fatty acids |
| PCT/GB2001/002717 WO2002002105A1 (en) | 2000-06-29 | 2001-06-20 | Therapeutic combinations of fatty acids |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2004501969A JP2004501969A (ja) | 2004-01-22 |
| JP2004501969A5 true JP2004501969A5 (enExample) | 2008-08-07 |
Family
ID=9894724
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2002506727A Pending JP2004501969A (ja) | 2000-06-29 | 2001-06-20 | 脂肪酸の治療用組合せ |
Country Status (32)
| Country | Link |
|---|---|
| US (1) | US6479544B1 (enExample) |
| EP (1) | EP1296670B1 (enExample) |
| JP (1) | JP2004501969A (enExample) |
| KR (1) | KR20030016306A (enExample) |
| CN (1) | CN100469363C (enExample) |
| AT (1) | ATE315388T1 (enExample) |
| AU (2) | AU7427601A (enExample) |
| BR (1) | BR0112073A (enExample) |
| CA (1) | CA2411368C (enExample) |
| CZ (1) | CZ20024173A3 (enExample) |
| DE (1) | DE60116625T2 (enExample) |
| DK (1) | DK1296670T3 (enExample) |
| EE (1) | EE05148B1 (enExample) |
| ES (1) | ES2256250T3 (enExample) |
| GB (1) | GB0016045D0 (enExample) |
| HR (1) | HRP20030035A2 (enExample) |
| HU (1) | HUP0301107A2 (enExample) |
| IL (1) | IL153458A0 (enExample) |
| IS (1) | IS2226B (enExample) |
| MX (1) | MXPA02012689A (enExample) |
| MY (1) | MY117830A (enExample) |
| NO (1) | NO329868B1 (enExample) |
| NZ (1) | NZ522916A (enExample) |
| PL (1) | PL359185A1 (enExample) |
| PT (1) | PT1296670E (enExample) |
| RU (1) | RU2276975C2 (enExample) |
| SK (1) | SK287209B6 (enExample) |
| TW (1) | TWI285549B (enExample) |
| UA (1) | UA76108C2 (enExample) |
| WO (1) | WO2002002105A1 (enExample) |
| YU (1) | YU99602A (enExample) |
| ZA (1) | ZA200300198B (enExample) |
Families Citing this family (78)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9901809D0 (en) | 1999-01-27 | 1999-03-17 | Scarista Limited | Highly purified ethgyl epa and other epa derivatives for psychiatric and neurological disorderes |
| DE10006836B4 (de) * | 2000-04-18 | 2005-03-24 | Bitec Gmbh | Verwendung von Omega-3-Fettsäuren und/oder Verbindungen von Omega-3-Fettsäuren |
| ITMI20010129A1 (it) | 2001-01-25 | 2002-07-25 | Pharmacia & Upjohn Spa | Acidi grassi essenziali nella terapia di insufficienza cardiaca e scompenso cardiaco |
| JP2003048831A (ja) * | 2001-08-02 | 2003-02-21 | Suntory Ltd | 脳機能の低下に起因する症状あるいは疾患の予防又は改善作用を有する組成物 |
| EP2283838A3 (en) | 2002-09-27 | 2011-04-20 | Martek Biosciences Corporation | Docosahexaenoic acid for treating subclinical inflammation |
| DE10254584A1 (de) * | 2002-11-22 | 2004-06-09 | HORST HEIRLER PROJEKTE für Ernährung, Medizin, Ökologie | Verwendung von mittelkettigen Triglyceriden (MCT) zur ernährungsphysiologischen Optimierung des Fettsäurenspektrums in einem diätetischen Lebensmittel für Diabetiker |
| GB0311081D0 (en) | 2003-05-14 | 2003-06-18 | Btg Internat Limted | Treatment of neurodegenerative conditions |
| FR2856304B1 (fr) * | 2003-06-20 | 2006-03-03 | Natural Product Consulting | Composition pour la prevention des infections du systeme urinaire |
| JP2007502805A (ja) | 2003-08-18 | 2007-02-15 | ビーティージー・インターナショナル・リミテッド | 神経変性状態の処置 |
| US7875291B1 (en) | 2003-09-05 | 2011-01-25 | Glu-Pro, Inc. | Composition for managing diabetes, obesity, and hyperlipidemia and associated methods |
| JP4522075B2 (ja) * | 2003-10-29 | 2010-08-11 | サントリーホールディングス株式会社 | 血管の老化に起因する症状あるいは疾患の予防又は改善作用を有する組成物 |
| US20050249823A1 (en) * | 2003-11-04 | 2005-11-10 | Murphy Tanya K | Methods for the prevention or amelioration of neuropsychiatric and related diseases |
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| EP1543735B1 (en) * | 2003-12-20 | 2015-10-07 | Nestec S.A. | Nutritional composition for wound healing |
| AU2005208832A1 (en) * | 2004-01-19 | 2005-08-11 | Martek Biosciences Corporation | Reelin deficiency or dysfunction and methods related thereto |
| ES2286558T5 (es) | 2004-08-24 | 2013-10-15 | N.V. Nutricia | Composición nutritiva que comprende transgalactooligosacáridos indigeribles y sacáridos de galactosa digeribles |
| JP2006083136A (ja) * | 2004-09-17 | 2006-03-30 | Suntory Ltd | ストレスに起因する脳機能の低下およびそれに伴う症状あるいは疾患の予防又は改善作用を有する組成物 |
| JP4993852B2 (ja) | 2004-09-17 | 2012-08-08 | サントリーホールディングス株式会社 | ストレスに起因する行動異常を伴う症状あるいは疾患の予防又は改善作用を有する組成物 |
| US8092839B2 (en) * | 2004-12-13 | 2012-01-10 | Swing Aerobics Licensing, Inc. | Medicament for treatment of cancer and other diseases |
| US8431165B2 (en) * | 2004-12-13 | 2013-04-30 | Swing Aerobics Licensing, Inc. | Medicament for treatment of cancer and other diseases |
| US20060135610A1 (en) * | 2004-12-22 | 2006-06-22 | Bortz Jonathan D | Cardiovascular compositions |
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| US20090054523A1 (en) * | 2005-01-24 | 2009-02-26 | Morten Bryhn | Use of a Fatty Acid Composition Containing DHA for the Production of a Medical Product or a Food Stuff for the Treatment of Amyloidos-Related Diseases |
| EP3581178B1 (en) | 2005-02-14 | 2023-08-30 | Suntory Holdings Limited | Composition containing dihomo-(gamma)-linolenic acid (dgla) as active ingredient |
| GB0504362D0 (en) | 2005-03-02 | 2005-04-06 | Btg Int Ltd | Cytokine modulators |
| JP5967855B2 (ja) | 2005-06-30 | 2016-08-10 | サントリーホールディングス株式会社 | 日中活動量の低下および／又はうつ症状の改善作用を有する組成物 |
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| GB0607949D0 (en) * | 2006-04-21 | 2006-05-31 | Minster Res The Ltd | Mono and combination therapy |
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| CN101631542B (zh) * | 2006-12-28 | 2011-12-21 | 三得利控股株式会社 | 神经再生剂 |
| WO2009009040A2 (en) * | 2007-07-06 | 2009-01-15 | Baum Seth J | Fatty acid compositions and methods of use |
| US8343753B2 (en) * | 2007-11-01 | 2013-01-01 | Wake Forest University School Of Medicine | Compositions, methods, and kits for polyunsaturated fatty acids from microalgae |
| ES2632967T3 (es) | 2008-09-02 | 2017-09-18 | Amarin Pharmaceuticals Ireland Limited | Composición farmacéutica que comprende ácido eicosapentaenoico y ácido nicotínico y métodos de uso de la misma |
| SI2596786T1 (sl) | 2009-02-10 | 2020-03-31 | Amarin Pharmaceuticals Ireland Limited, | Uporaba etilestra eikozapentaenojske kisline za zdravljenje hipertrigliceridemije |
| LT2424356T (lt) | 2009-04-29 | 2017-11-27 | Amarin Pharmaceuticals Ireland Limited | Stabili farmacinė kompozicija ir jos panaudojimo būdai |
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| NZ807894A (en) | 2009-04-29 | 2025-08-29 | Amarin Pharmaceuticals Ie Ltd | Pharmaceutical compositions comprising epa and a cardiovascular agent and methods of using the same |
| KR102012111B1 (ko) | 2009-06-15 | 2019-08-19 | 아마린 파마, 인크. | 병용 스타틴 요법을 받는 대상체에서 ｌｄｌ－ｃ 수준을 상승시키지 않으면서 트리글리세리드를 저하시키기 위한 조성물 및 방법 |
| RU2012116079A (ru) | 2009-09-23 | 2013-10-27 | АМАРИН КОРПОРЕЙШН ПиЭлСи | Фармацевтическая композиция, включающая омега-3 жирную кислоту и гидроксипроизводное статина и способы ее применения |
| US11712429B2 (en) | 2010-11-29 | 2023-08-01 | Amarin Pharmaceuticals Ireland Limited | Low eructation composition and methods for treating and/or preventing cardiovascular disease in a subject with fish allergy/hypersensitivity |
| NZ712068A (en) | 2010-11-29 | 2017-03-31 | Amarin Pharmaceuticals Ie Ltd | Low eructation composition and methods for treating and/or preventing cardiovascular disease in a subject with fish allergy/hypersensitivity |
| US8865685B2 (en) | 2011-06-30 | 2014-10-21 | Johnson & Johnson Vision Care, Inc. | Esters for treatment of ocular inflammatory conditions |
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| US11291643B2 (en) | 2011-11-07 | 2022-04-05 | Amarin Pharmaceuticals Ireland Limited | Methods of treating hypertriglyceridemia |
| EP2775837A4 (en) | 2011-11-07 | 2015-10-28 | Amarin Pharmaceuticals Ie Ltd | METHODS OF TREATING HYPERTRIGLYCERIDEMIA |
| EP2800469B1 (en) | 2012-01-06 | 2021-08-25 | Amarin Pharmaceuticals Ireland Limited | Compositions and methods for lowering levels of high-sensitivity (hs-crp) in a subject |
| JP6399655B2 (ja) | 2012-01-06 | 2018-10-03 | オムセラ・ファーマシューティカルズ・インコーポレイテッド | 遊離酸型のオメガ−３多価不飽和脂肪酸のｄｐａ濃縮組成物 |
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| EP2861227A4 (en) | 2012-06-17 | 2016-01-27 | Matinas Biopharma Inc | OMEGA-3 PENTAIC ACID COMPOSITIONS AND METHODS OF USE |
| CN104582698A (zh) | 2012-06-29 | 2015-04-29 | 阿玛林制药爱尔兰有限公司 | 在接受抑制素治疗的受试者中降低心血管事件风险的方法 |
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| US9452151B2 (en) | 2013-02-06 | 2016-09-27 | Amarin Pharmaceuticals Ireland Limited | Methods of reducing apolipoprotein C-III |
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| US20140271841A1 (en) | 2013-03-15 | 2014-09-18 | Amarin Pharmaceuticals Ireland Limited | Pharmaceutical composition comprising eicosapentaenoic acid and derivatives thereof and a statin |
| US10966968B2 (en) | 2013-06-06 | 2021-04-06 | Amarin Pharmaceuticals Ireland Limited | Co-administration of rosiglitazone and eicosapentaenoic acid or a derivative thereof |
| US20150065572A1 (en) * | 2013-09-04 | 2015-03-05 | Amarin Pharmaceuticals Ireland Limited | Methods of treating or preventing prostate cancer |
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| TW201900160A (zh) | 2017-05-19 | 2019-01-01 | 愛爾蘭商艾瑪琳製藥愛爾蘭有限公司 | 用於降低腎功能下降之個體中的三酸甘油酯之組合物及方法 |
| US11058661B2 (en) | 2018-03-02 | 2021-07-13 | Amarin Pharmaceuticals Ireland Limited | Compositions and methods for lowering triglycerides in a subject on concomitant statin therapy and having hsCRP levels of at least about 2 mg/L |
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| CN1212867A (zh) * | 1997-09-29 | 1999-04-07 | 宋凤亭 | 防治心脑血管疾病的组合物 |
| DE19757414A1 (de) * | 1997-12-23 | 1999-07-01 | Nutricia Nv | Fettmischung |
| NZ511071A (en) | 1998-10-15 | 2004-01-30 | Dsm N | PUFA supplements |
| SE9900941D0 (sv) * | 1998-12-23 | 1999-03-16 | Nomet Management Serv Bv | Novel retinoic acid derivatives and their use |
| GB9901809D0 (en) | 1999-01-27 | 1999-03-17 | Scarista Limited | Highly purified ethgyl epa and other epa derivatives for psychiatric and neurological disorderes |
-
2000
- 2000-06-29 GB GBGB0016045.7A patent/GB0016045D0/en not_active Ceased
-
2001
- 2001-06-20 PL PL01359185A patent/PL359185A1/xx not_active Application Discontinuation
- 2001-06-20 WO PCT/GB2001/002717 patent/WO2002002105A1/en not_active Ceased
- 2001-06-20 CA CA002411368A patent/CA2411368C/en not_active Expired - Fee Related
- 2001-06-20 AU AU7427601A patent/AU7427601A/xx active Pending
- 2001-06-20 PT PT01940775T patent/PT1296670E/pt unknown
- 2001-06-20 CN CNB01811931XA patent/CN100469363C/zh not_active Expired - Fee Related
- 2001-06-20 CZ CZ20024173A patent/CZ20024173A3/cs unknown
- 2001-06-20 JP JP2002506727A patent/JP2004501969A/ja active Pending
- 2001-06-20 NZ NZ522916A patent/NZ522916A/en unknown
- 2001-06-20 DE DE60116625T patent/DE60116625T2/de not_active Expired - Lifetime
- 2001-06-20 MX MXPA02012689A patent/MXPA02012689A/es active IP Right Grant
- 2001-06-20 DK DK01940775T patent/DK1296670T3/da active
- 2001-06-20 EP EP01940775A patent/EP1296670B1/en not_active Expired - Lifetime
- 2001-06-20 HR HR20030035A patent/HRP20030035A2/hr not_active Application Discontinuation
- 2001-06-20 KR KR1020027017649A patent/KR20030016306A/ko not_active Ceased
- 2001-06-20 BR BR0112073-5A patent/BR0112073A/pt not_active Application Discontinuation
- 2001-06-20 UA UA20021210705A patent/UA76108C2/uk unknown
- 2001-06-20 IL IL15345801A patent/IL153458A0/xx not_active IP Right Cessation
- 2001-06-20 ES ES01940775T patent/ES2256250T3/es not_active Expired - Lifetime
- 2001-06-20 YU YU99602A patent/YU99602A/sh unknown
- 2001-06-20 SK SK1816-2002A patent/SK287209B6/sk not_active IP Right Cessation
- 2001-06-20 EE EEP200200718A patent/EE05148B1/xx not_active IP Right Cessation
- 2001-06-20 AU AU2001274276A patent/AU2001274276B2/en not_active Ceased
- 2001-06-20 HU HU0301107A patent/HUP0301107A2/hu unknown
- 2001-06-20 AT AT01940775T patent/ATE315388T1/de active
- 2001-06-20 RU RU2002133098/15A patent/RU2276975C2/ru not_active IP Right Cessation
- 2001-06-21 MY MYPI20012947A patent/MY117830A/en unknown
- 2001-06-29 US US09/893,473 patent/US6479544B1/en not_active Expired - Lifetime
- 2001-06-29 TW TW090116201A patent/TWI285549B/zh not_active IP Right Cessation
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2002
- 2002-11-29 IS IS6644A patent/IS2226B/is unknown
- 2002-12-18 NO NO20026093A patent/NO329868B1/no not_active IP Right Cessation
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2003
- 2003-01-08 ZA ZA200300198A patent/ZA200300198B/en unknown
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