JP2004501962A5 - - Google Patents
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- JP2004501962A5 JP2004501962A5 JP2002506712A JP2002506712A JP2004501962A5 JP 2004501962 A5 JP2004501962 A5 JP 2004501962A5 JP 2002506712 A JP2002506712 A JP 2002506712A JP 2002506712 A JP2002506712 A JP 2002506712A JP 2004501962 A5 JP2004501962 A5 JP 2004501962A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutical composition
- composition according
- disease
- symptom
- inflammatory disease
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 239000008194 pharmaceutical composition Substances 0.000 claims 27
- 208000027866 inflammatory disease Diseases 0.000 claims 13
- 208000024891 symptom Diseases 0.000 claims 13
- 229910052739 hydrogen Inorganic materials 0.000 claims 7
- 239000001257 hydrogen Substances 0.000 claims 7
- 125000004178 (C1-C4) alkyl group Chemical group 0.000 claims 6
- -1 nitro, methoxy Chemical group 0.000 claims 6
- 125000003710 aryl alkyl group Chemical group 0.000 claims 5
- UWYZHKAOTLEWKK-UHFFFAOYSA-N 1,2,3,4-tetrahydroisoquinoline Chemical compound C1=CC=C2CNCCC2=C1 UWYZHKAOTLEWKK-UHFFFAOYSA-N 0.000 claims 4
- 201000001320 Atherosclerosis Diseases 0.000 claims 4
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 claims 4
- NQRYJNQNLNOLGT-UHFFFAOYSA-N Piperidine Chemical compound C1CCNCC1 NQRYJNQNLNOLGT-UHFFFAOYSA-N 0.000 claims 4
- 201000010099 disease Diseases 0.000 claims 4
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 4
- RWRDLPDLKQPQOW-UHFFFAOYSA-N Pyrrolidine Chemical compound C1CCNC1 RWRDLPDLKQPQOW-UHFFFAOYSA-N 0.000 claims 3
- 125000000217 alkyl group Chemical group 0.000 claims 3
- 229910052736 halogen Inorganic materials 0.000 claims 3
- 150000002367 halogens Chemical group 0.000 claims 3
- 125000000623 heterocyclic group Chemical group 0.000 claims 3
- 150000002431 hydrogen Chemical class 0.000 claims 3
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 claims 3
- ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical compound [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 claims 2
- 208000017189 Gastrointestinal inflammatory disease Diseases 0.000 claims 2
- CEIXWJHURKEBMQ-UHFFFAOYSA-N Heliamine Chemical compound C1CNCC2=C1C=C(OC)C(OC)=C2 CEIXWJHURKEBMQ-UHFFFAOYSA-N 0.000 claims 2
- 101000694615 Homo sapiens Membrane primary amine oxidase Proteins 0.000 claims 2
- 206010061218 Inflammation Diseases 0.000 claims 2
- 208000017442 Retinal disease Diseases 0.000 claims 2
- 206010038923 Retinopathy Diseases 0.000 claims 2
- 206010047115 Vasculitis Diseases 0.000 claims 2
- 210000001789 adipocyte Anatomy 0.000 claims 2
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 claims 2
- 125000001589 carboacyl group Chemical group 0.000 claims 2
- 230000023852 carbohydrate metabolic process Effects 0.000 claims 2
- 235000021256 carbohydrate metabolism Nutrition 0.000 claims 2
- 230000003915 cell function Effects 0.000 claims 2
- 229910052801 chlorine Inorganic materials 0.000 claims 2
- 239000000460 chlorine Substances 0.000 claims 2
- 150000001875 compounds Chemical class 0.000 claims 2
- 210000002808 connective tissue Anatomy 0.000 claims 2
- 230000004069 differentiation Effects 0.000 claims 2
- 230000006870 function Effects 0.000 claims 2
- 230000004054 inflammatory process Effects 0.000 claims 2
- 230000002401 inhibitory effect Effects 0.000 claims 2
- 208000002551 irritable bowel syndrome Diseases 0.000 claims 2
- 201000008482 osteoarthritis Diseases 0.000 claims 2
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 claims 2
- 230000002685 pulmonary effect Effects 0.000 claims 2
- 150000003839 salts Chemical class 0.000 claims 2
- 210000000329 smooth muscle myocyte Anatomy 0.000 claims 2
- 208000019553 vascular disease Diseases 0.000 claims 2
- DJHZFBWBKDHBBA-UHFFFAOYSA-N (2-amino-6,7-dimethoxy-3,4-dihydro-1h-isoquinolin-1-yl)methanol;hydrochloride Chemical compound Cl.C1CN(N)C(CO)C2=C1C=C(OC)C(OC)=C2 DJHZFBWBKDHBBA-UHFFFAOYSA-N 0.000 claims 1
- LVINSXAWZGKMLE-BQYQJAHWSA-N (E)-4-[2-[amino(methyl)amino]-1-(4-methoxyphenyl)ethoxy]-4-oxobut-2-enoic acid Chemical compound COC1=CC=C(C(CN(C)N)OC(=O)\C=C\C(O)=O)C=C1 LVINSXAWZGKMLE-BQYQJAHWSA-N 0.000 claims 1
- YPGYFNRGZQMJCR-OHZSCMDDSA-N (Z)-4-[(1R,2S)-2-[amino(methyl)amino]-1-phenylpropoxy]-4-oxobut-2-enoic acid Chemical compound OC(=O)\C=C/C(=O)O[C@@H]([C@H](C)N(C)N)C1=CC=CC=C1 YPGYFNRGZQMJCR-OHZSCMDDSA-N 0.000 claims 1
- DTGXOXFDJLYHMN-FPLPWBNLSA-N (Z)-4-[2-[amino(methyl)amino]-1-phenylethoxy]-4-oxobut-2-enoic acid Chemical compound OC(=O)\C=C/C(=O)OC(CN(N)C)C1=CC=CC=C1 DTGXOXFDJLYHMN-FPLPWBNLSA-N 0.000 claims 1
- QCUISTGPEASKHD-FPLPWBNLSA-N (Z)-4-[2-[amino(methyl)amino]-2-phenylethoxy]-4-oxobut-2-enoic acid Chemical compound OC(=O)\C=C/C(=O)OCC(N(N)C)C1=CC=CC=C1 QCUISTGPEASKHD-FPLPWBNLSA-N 0.000 claims 1
- MQZVEJZQKNMKOL-WLHGVMLRSA-N (e)-but-2-enedioic acid;1-[2-methoxy-2-(3-methoxyphenyl)ethyl]-1-methylhydrazine Chemical compound OC(=O)\C=C\C(O)=O.CN(N)CC(OC)C1=CC=CC(OC)=C1 MQZVEJZQKNMKOL-WLHGVMLRSA-N 0.000 claims 1
- 208000024827 Alzheimer disease Diseases 0.000 claims 1
- 206010002556 Ankylosing Spondylitis Diseases 0.000 claims 1
- 208000031104 Arterial Occlusive disease Diseases 0.000 claims 1
- 206010061666 Autonomic neuropathy Diseases 0.000 claims 1
- 208000027496 Behcet disease Diseases 0.000 claims 1
- 208000009137 Behcet syndrome Diseases 0.000 claims 1
- CPELXLSAUQHCOX-UHFFFAOYSA-M Bromide Chemical group [Br-] CPELXLSAUQHCOX-UHFFFAOYSA-M 0.000 claims 1
- 208000025985 Central nervous system inflammatory disease Diseases 0.000 claims 1
- 206010008685 Chondritis Diseases 0.000 claims 1
- 208000006545 Chronic Obstructive Pulmonary Disease Diseases 0.000 claims 1
- 206010009900 Colitis ulcerative Diseases 0.000 claims 1
- 208000011231 Crohn disease Diseases 0.000 claims 1
- 206010012438 Dermatitis atopic Diseases 0.000 claims 1
- 206010012442 Dermatitis contact Diseases 0.000 claims 1
- 208000006926 Discoid Lupus Erythematosus Diseases 0.000 claims 1
- 208000000059 Dyspnea Diseases 0.000 claims 1
- 206010013975 Dyspnoeas Diseases 0.000 claims 1
- 206010015150 Erythema Diseases 0.000 claims 1
- 206010016228 Fasciitis Diseases 0.000 claims 1
- 206010016654 Fibrosis Diseases 0.000 claims 1
- 208000003790 Foot Ulcer Diseases 0.000 claims 1
- 208000007465 Giant cell arteritis Diseases 0.000 claims 1
- 206010072579 Granulomatosis with polyangiitis Diseases 0.000 claims 1
- 208000032382 Ischaemic stroke Diseases 0.000 claims 1
- 208000012659 Joint disease Diseases 0.000 claims 1
- 208000003456 Juvenile Arthritis Diseases 0.000 claims 1
- 206010059176 Juvenile idiopathic arthritis Diseases 0.000 claims 1
- 208000003250 Mixed connective tissue disease Diseases 0.000 claims 1
- 208000000112 Myalgia Diseases 0.000 claims 1
- 206010029164 Nephrotic syndrome Diseases 0.000 claims 1
- 208000008589 Obesity Diseases 0.000 claims 1
- 108090000854 Oxidoreductases Proteins 0.000 claims 1
- 102000004316 Oxidoreductases Human genes 0.000 claims 1
- 206010036105 Polyneuropathy Diseases 0.000 claims 1
- 201000004681 Psoriasis Diseases 0.000 claims 1
- 201000001263 Psoriatic Arthritis Diseases 0.000 claims 1
- 208000036824 Psoriatic arthropathy Diseases 0.000 claims 1
- 208000003782 Raynaud disease Diseases 0.000 claims 1
- 208000012322 Raynaud phenomenon Diseases 0.000 claims 1
- 208000033464 Reiter syndrome Diseases 0.000 claims 1
- 206010063837 Reperfusion injury Diseases 0.000 claims 1
- 208000025747 Rheumatic disease Diseases 0.000 claims 1
- 241001303601 Rosacea Species 0.000 claims 1
- 208000021386 Sjogren Syndrome Diseases 0.000 claims 1
- 201000009594 Systemic Scleroderma Diseases 0.000 claims 1
- 206010042953 Systemic sclerosis Diseases 0.000 claims 1
- 206010043540 Thromboangiitis obliterans Diseases 0.000 claims 1
- 201000006704 Ulcerative Colitis Diseases 0.000 claims 1
- 230000002159 abnormal effect Effects 0.000 claims 1
- 208000002399 aphthous stomatitis Diseases 0.000 claims 1
- 125000003435 aroyl group Chemical group 0.000 claims 1
- 208000021328 arterial occlusion Diseases 0.000 claims 1
- 208000006673 asthma Diseases 0.000 claims 1
- 125000004429 atom Chemical group 0.000 claims 1
- 201000008937 atopic dermatitis Diseases 0.000 claims 1
- 210000003169 central nervous system Anatomy 0.000 claims 1
- 150000001805 chlorine compounds Chemical group 0.000 claims 1
- 208000019069 chronic childhood arthritis Diseases 0.000 claims 1
- 208000010247 contact dermatitis Diseases 0.000 claims 1
- 208000004921 cutaneous lupus erythematosus Diseases 0.000 claims 1
- 125000000113 cyclohexyl group Chemical group [H]C1([H])C([H])([H])C([H])([H])C([H])(*)C([H])([H])C1([H])[H] 0.000 claims 1
- 201000001981 dermatomyositis Diseases 0.000 claims 1
- 206010012601 diabetes mellitus Diseases 0.000 claims 1
- 231100000321 erythema Toxicity 0.000 claims 1
- 230000004761 fibrosis Effects 0.000 claims 1
- 125000001072 heteroaryl group Chemical group 0.000 claims 1
- XMBWDFGMSWQBCA-UHFFFAOYSA-N hydrogen iodide Chemical group I XMBWDFGMSWQBCA-UHFFFAOYSA-N 0.000 claims 1
- 238000000338 in vitro Methods 0.000 claims 1
- 208000015181 infectious disease Diseases 0.000 claims 1
- 230000005764 inhibitory process Effects 0.000 claims 1
- 208000012947 ischemia reperfusion injury Diseases 0.000 claims 1
- 201000002215 juvenile rheumatoid arthritis Diseases 0.000 claims 1
- 208000017169 kidney disease Diseases 0.000 claims 1
- 201000011486 lichen planus Diseases 0.000 claims 1
- 210000004185 liver Anatomy 0.000 claims 1
- 238000000034 method Methods 0.000 claims 1
- 125000000956 methoxy group Chemical group [H]C([H])([H])O* 0.000 claims 1
- 201000005518 mononeuropathy Diseases 0.000 claims 1
- 210000002200 mouth mucosa Anatomy 0.000 claims 1
- 201000006417 multiple sclerosis Diseases 0.000 claims 1
- 208000031225 myocardial ischemia Diseases 0.000 claims 1
- 235000020824 obesity Nutrition 0.000 claims 1
- 230000000414 obstructive effect Effects 0.000 claims 1
- 230000002093 peripheral effect Effects 0.000 claims 1
- 208000005987 polymyositis Diseases 0.000 claims 1
- 230000007824 polyneuropathy Effects 0.000 claims 1
- 239000011148 porous material Substances 0.000 claims 1
- 125000003072 pyrazolidinyl group Chemical group 0.000 claims 1
- 208000002574 reactive arthritis Diseases 0.000 claims 1
- 230000000306 recurrent effect Effects 0.000 claims 1
- 230000000552 rheumatic effect Effects 0.000 claims 1
- 206010039073 rheumatoid arthritis Diseases 0.000 claims 1
- 201000004700 rosacea Diseases 0.000 claims 1
- 229920006395 saturated elastomer Polymers 0.000 claims 1
- 239000012453 solvate Substances 0.000 claims 1
- 208000003265 stomatitis Diseases 0.000 claims 1
- 125000005346 substituted cycloalkyl group Chemical group 0.000 claims 1
- 208000011580 syndromic disease Diseases 0.000 claims 1
- 201000000596 systemic lupus erythematosus Diseases 0.000 claims 1
- 206010043207 temporal arteritis Diseases 0.000 claims 1
- 230000001732 thrombotic effect Effects 0.000 claims 1
- 230000002792 vascular Effects 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US21634100P | 2000-07-05 | 2000-07-05 | |
| PCT/FI2001/000638 WO2002002090A2 (en) | 2000-07-05 | 2001-07-04 | Inhibitors of copper-containing amine oxidases |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2004501962A JP2004501962A (ja) | 2004-01-22 |
| JP2004501962A5 true JP2004501962A5 (OSRAM) | 2005-03-03 |
Family
ID=22806663
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2002507795A Withdrawn JP2004502682A (ja) | 2000-07-05 | 2001-07-04 | 銅含有アミン・オキシダーゼの阻害剤 |
| JP2002506712A Withdrawn JP2004501962A (ja) | 2000-07-05 | 2001-07-04 | 銅含有アミン・オキシダーゼの阻害剤 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2002507795A Withdrawn JP2004502682A (ja) | 2000-07-05 | 2001-07-04 | 銅含有アミン・オキシダーゼの阻害剤 |
Country Status (14)
| Country | Link |
|---|---|
| US (2) | US6624202B2 (OSRAM) |
| EP (2) | EP1301495A2 (OSRAM) |
| JP (2) | JP2004502682A (OSRAM) |
| CN (2) | CN1450998A (OSRAM) |
| AU (3) | AU2001282163B2 (OSRAM) |
| CA (2) | CA2414799A1 (OSRAM) |
| HU (2) | HUP0301336A3 (OSRAM) |
| IL (2) | IL153767A0 (OSRAM) |
| NO (2) | NO20026283L (OSRAM) |
| NZ (2) | NZ523464A (OSRAM) |
| PL (2) | PL360374A1 (OSRAM) |
| RU (2) | RU2003103286A (OSRAM) |
| WO (2) | WO2002002090A2 (OSRAM) |
| ZA (2) | ZA200300064B (OSRAM) |
Families Citing this family (35)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PL360374A1 (en) | 2000-07-05 | 2004-09-06 | Biotie Therapies Corporation | Inhibitors of copper-containing amine oxidases |
| US6982286B2 (en) | 2001-07-12 | 2006-01-03 | Biotie Therapies Corp. | Carbocyclic hydrazino inhibitors of copper-containing amine oxidases |
| AR042941A1 (es) * | 2003-01-27 | 2005-07-06 | Fujisawa Pharmaceutical Co | Derivados de tiazol, su preparacion, composiciones farmaceuticas que los contienen y su uso en la fabricacion de medicamentos inhibidores de la proteina-1 de adhesion vascular (vap-1) |
| CN1794988B (zh) * | 2003-03-31 | 2010-07-28 | 株式会社·R-技术上野 | 用于治疗血管渗透性过高疾病的组合物 |
| JP2007509605A (ja) * | 2003-05-26 | 2007-04-19 | バイオティ セラピーズ コーポレイション | 結晶性タンパク質ｖａｐ−１その用途 |
| FI20031927A0 (fi) * | 2003-12-31 | 2003-12-31 | Faron Pharmaceuticals Oy | Terapeuttisesti vaikuttavia aineita ja niiden käyttö |
| FI20040136A0 (fi) * | 2004-01-30 | 2004-01-30 | Faron Pharmaceuticals Oy | Erityisesti diabeetikoille soveltuvia koostumuksia |
| US8119651B2 (en) | 2004-01-30 | 2012-02-21 | Biotie Therapies Corp. | Compositions useful especially for treatment or prevention of metabolic syndrome |
| JP2007519688A (ja) * | 2004-01-30 | 2007-07-19 | ファロン ファーマシューティカルズ オサケ ユキチュア | メタボリックシンドロームの治療または予防に特に有効な組成物 |
| FI20040270A0 (fi) * | 2004-02-20 | 2004-02-20 | Biotie Therapies Oyj | Kuparia sisältävien amiinioksidaasien imhibiittoreina käyttökelpoiset hydratsinoalkoholijohdannaiset |
| DE602005013793D1 (de) * | 2004-07-27 | 2009-05-20 | Astellas Pharma Inc | Thiazolderivate mit vap-1-hemmender wirkung |
| CA2579889A1 (en) * | 2004-09-09 | 2006-03-16 | Astellas Pharma Inc. | Thiazole derivatives having vap-1 inhibitory activity |
| JP4140630B2 (ja) * | 2005-11-10 | 2008-08-27 | Ｔｄｋ株式会社 | 磁気ヘッドアセンブリ及び磁気ヘッドアセンブリの製造方法 |
| US8636995B2 (en) * | 2006-08-31 | 2014-01-28 | Cardiac Pacemakers, Inc. | Methods and devices to regulate stem cell homing |
| US8372399B2 (en) * | 2006-08-31 | 2013-02-12 | Cardiac Pacemakers, Inc. | Bispecific antibodies and agents to enhance stem cell homing |
| US20080058922A1 (en) * | 2006-08-31 | 2008-03-06 | Cardiac Pacemakers, Inc. | Methods and devices employing vap-1 inhibitors |
| FI20061156A0 (fi) | 2006-12-27 | 2006-12-27 | Elina Kivi | Uusia peptidejä |
| US20090170770A1 (en) * | 2007-11-06 | 2009-07-02 | Ali Hafezi-Moghadam | Methods and compositions for treating conditions associated with angiogenesis using a vascular adhesion protein-1 (vap 1) inhibitor |
| NZ585528A (en) | 2007-11-21 | 2012-08-31 | Pharmaxis Ltd | Haloallylamine inhibitors of ssao/vap-1 and uses therefor |
| TWI437986B (zh) | 2008-01-31 | 2014-05-21 | R Tech Ueno Ltd | 噻唑衍生物及使用該衍生物作為ｖａｐ－１抑制劑之用途 |
| TWI490214B (zh) * | 2008-05-30 | 2015-07-01 | 艾德克 上野股份有限公司 | 苯或噻吩衍生物及該等作為ｖａｐ－１抑制劑之用途 |
| US8906642B2 (en) | 2008-09-03 | 2014-12-09 | Universitat Autonoma De Barcelona | Methods and compositions for the treatment and diagnosis of haemorrhagic conversion |
| RU2400233C1 (ru) | 2009-07-07 | 2010-09-27 | Общество с ограниченной ответственностью "Вирфарм" | Способ лечения заболеваний печени различного генеза |
| UA112154C2 (uk) * | 2009-09-08 | 2016-08-10 | Біоті Терапіс Корп. | Застосування повністю людського анти-vap-1-антитіла для лікування фіброзних станів |
| ES2651690T3 (es) | 2009-09-16 | 2018-01-29 | Astellas Pharma Inc. | Compuesto de glicina |
| RU2010145439A (ru) | 2010-11-08 | 2012-05-20 | Виктор Вениаминович Тец (RU) | Средство для лечения поражений печени, вызванных воздействием химических или биологических агентов |
| FI20115234A0 (fi) | 2011-03-08 | 2011-03-08 | Biotie Therapies Corp | Uusia pyridatsinoni- ja pyridoniyhdisteitä |
| HUE028394T2 (en) | 2011-03-15 | 2016-12-28 | Astellas Pharma Inc | Guanidine compound |
| US20160113893A1 (en) | 2013-06-12 | 2016-04-28 | Proximagen Limited | New therapeutic uses of enzyme inhibitors |
| HUE042625T2 (hu) | 2014-04-15 | 2019-07-29 | Pecsi Tudomanyegyetem | Szemikarbazid-szenzitiv amin-oxidáz gátlók fájdalomcsillapítóként való alkalmazásra traumás neuropátiában és neurogén gyulladásban |
| WO2015189534A1 (en) | 2014-06-12 | 2015-12-17 | Proximagen Limited | Vap-1 inhibitors for treating muscular dystrophy |
| RU2595868C1 (ru) | 2015-03-27 | 2016-08-27 | Виктор Вениаминович Тец | Лекарственное средство с гепатопротекторной активностью |
| JP2018076236A (ja) | 2015-06-05 | 2018-05-17 | 株式会社アールテック・ウエノ | がんを処置するための医薬組成物 |
| WO2017098236A1 (en) | 2015-12-07 | 2017-06-15 | Proximagen Limited | Vap-1 inhibitors for treating pain |
| CN109810041B (zh) * | 2017-11-21 | 2023-08-15 | 药捷安康(南京)科技股份有限公司 | 卤代烯丙基胺类ssao/vap-1抑制剂及其应用 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3377345A (en) * | 1966-09-23 | 1968-04-09 | Dow Chemical Co | Substituted 3, 4, 5, 6-tetrahydro-2h-1, 3, 4-oxadiazin-2-one compounds and method ofpreparation thereof |
| US3486916A (en) | 1966-12-22 | 1969-12-30 | William A Cordon | Cement mixes and the production of articles therefrom |
| SE320311B (OSRAM) | 1968-07-15 | 1970-02-02 | Mo Och Domsjoe Ab | |
| EP0639972A1 (en) * | 1992-05-15 | 1995-03-01 | University Of Saskatchewan | Method for preventing endothelium damage in mammals and for alleviating pain associated with gout and arthritis |
| US5413634A (en) | 1993-08-06 | 1995-05-09 | Arco Chemical Technology, L.P. | Cement composition |
| CA2117585C (en) | 1993-09-14 | 2001-06-05 | Edward T. Shawl | Cement composition |
| AU2696795A (en) | 1994-08-25 | 1996-03-14 | W.R. Grace & Co.-Conn. | Shrinkage reduction cement composition |
| US5618344A (en) | 1995-03-06 | 1997-04-08 | W. R. Grace & Co.-Conn. | Cement composition |
| US5603760A (en) | 1995-09-18 | 1997-02-18 | W. R. Grace & Co.-Conn. | Cement admixture capable of inhibiting drying shrinkage and method of using same |
| US5556460A (en) | 1995-09-18 | 1996-09-17 | W.R. Grace & Co.-Conn. | Drying shrinkage cement admixture |
| PL360374A1 (en) | 2000-07-05 | 2004-09-06 | Biotie Therapies Corporation | Inhibitors of copper-containing amine oxidases |
-
2001
- 2001-07-04 PL PL36037401A patent/PL360374A1/xx not_active Application Discontinuation
- 2001-07-04 RU RU2003103286/15A patent/RU2003103286A/ru not_active Application Discontinuation
- 2001-07-04 CA CA002414799A patent/CA2414799A1/en not_active Abandoned
- 2001-07-04 AU AU2001282163A patent/AU2001282163B2/en not_active Ceased
- 2001-07-04 HU HU0301336A patent/HUP0301336A3/hu unknown
- 2001-07-04 AU AU8216301A patent/AU8216301A/xx active Pending
- 2001-07-04 IL IL15376701A patent/IL153767A0/xx unknown
- 2001-07-04 CA CA002414807A patent/CA2414807A1/en not_active Abandoned
- 2001-07-04 JP JP2002507795A patent/JP2004502682A/ja not_active Withdrawn
- 2001-07-04 NZ NZ523464A patent/NZ523464A/en unknown
- 2001-07-04 IL IL15376601A patent/IL153766A0/xx unknown
- 2001-07-04 EP EP01960763A patent/EP1301495A2/en not_active Withdrawn
- 2001-07-04 JP JP2002506712A patent/JP2004501962A/ja not_active Withdrawn
- 2001-07-04 RU RU2003103291/04A patent/RU2003103291A/ru not_active Application Discontinuation
- 2001-07-04 AU AU2001282162A patent/AU2001282162A1/en not_active Abandoned
- 2001-07-04 PL PL36035301A patent/PL360353A1/xx not_active Application Discontinuation
- 2001-07-04 HU HU0301625A patent/HUP0301625A3/hu unknown
- 2001-07-04 EP EP01960764A patent/EP1313718A2/en not_active Withdrawn
- 2001-07-04 WO PCT/FI2001/000638 patent/WO2002002090A2/en not_active Ceased
- 2001-07-04 CN CN01815102A patent/CN1450998A/zh active Pending
- 2001-07-04 CN CN01815101A patent/CN1450997A/zh active Pending
- 2001-07-04 NZ NZ523463A patent/NZ523463A/en unknown
- 2001-07-04 WO PCT/FI2001/000637 patent/WO2002002541A2/en not_active Ceased
- 2001-07-05 US US09/898,003 patent/US6624202B2/en not_active Expired - Fee Related
-
2002
- 2002-12-30 NO NO20026283A patent/NO20026283L/no not_active Application Discontinuation
- 2002-12-30 NO NO20026282A patent/NO20026282L/no not_active Application Discontinuation
-
2003
- 2003-01-03 ZA ZA200300064A patent/ZA200300064B/en unknown
- 2003-01-03 ZA ZA200300063A patent/ZA200300063B/en unknown
- 2003-07-21 US US10/622,581 patent/US20040106654A1/en not_active Abandoned
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