JP2004501865A5 - - Google Patents
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- Publication number
- JP2004501865A5 JP2004501865A5 JP2001562429A JP2001562429A JP2004501865A5 JP 2004501865 A5 JP2004501865 A5 JP 2004501865A5 JP 2001562429 A JP2001562429 A JP 2001562429A JP 2001562429 A JP2001562429 A JP 2001562429A JP 2004501865 A5 JP2004501865 A5 JP 2004501865A5
- Authority
- JP
- Japan
- Prior art keywords
- group
- compound
- optionally substituted
- alkyl
- heteroaryl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 150000001875 compounds Chemical class 0.000 claims 44
- 125000001072 heteroaryl group Chemical group 0.000 claims 39
- 229930195733 hydrocarbon Natural products 0.000 claims 27
- 150000002430 hydrocarbons Chemical class 0.000 claims 27
- 125000003107 substituted aryl group Chemical group 0.000 claims 24
- -1 4-phenylphenyl Chemical group 0.000 claims 23
- 239000004215 Carbon black (E152) Substances 0.000 claims 22
- 125000003118 aryl group Chemical group 0.000 claims 15
- 229910052739 hydrogen Inorganic materials 0.000 claims 12
- 239000001257 hydrogen Substances 0.000 claims 12
- 125000000217 alkyl group Chemical group 0.000 claims 11
- 125000005842 heteroatom Chemical group 0.000 claims 11
- 125000004435 hydrogen atom Chemical class [H]* 0.000 claims 11
- 125000000304 alkynyl group Chemical group 0.000 claims 10
- 229910052736 halogen Inorganic materials 0.000 claims 10
- 150000002367 halogens Chemical class 0.000 claims 10
- 229910052757 nitrogen Inorganic materials 0.000 claims 10
- 125000001424 substituent group Chemical group 0.000 claims 10
- 229910052717 sulfur Inorganic materials 0.000 claims 10
- 125000003342 alkenyl group Chemical group 0.000 claims 9
- 229910052799 carbon Inorganic materials 0.000 claims 9
- 125000005343 heterocyclic alkyl group Chemical group 0.000 claims 9
- 230000037396 body weight Effects 0.000 claims 8
- 229910052760 oxygen Inorganic materials 0.000 claims 7
- 239000003814 drug Substances 0.000 claims 5
- 241000894006 Bacteria Species 0.000 claims 3
- RJQXTJLFIWVMTO-TYNCELHUSA-N Methicillin Chemical compound COC1=CC=CC(OC)=C1C(=O)N[C@@H]1C(=O)N2[C@@H](C(O)=O)C(C)(C)S[C@@H]21 RJQXTJLFIWVMTO-TYNCELHUSA-N 0.000 claims 3
- 125000004429 atom Chemical group 0.000 claims 3
- 125000000753 cycloalkyl group Chemical group 0.000 claims 3
- 229960003085 meticillin Drugs 0.000 claims 3
- 125000004108 n-butyl group Chemical group [H]C([H])([H])C([H])([H])C([H])([H])C([H])([H])* 0.000 claims 3
- 125000000636 p-nitrophenyl group Chemical group [H]C1=C([H])C(=C([H])C([H])=C1*)[N+]([O-])=O 0.000 claims 3
- 125000000547 substituted alkyl group Chemical group 0.000 claims 3
- 125000006305 3-iodophenyl group Chemical group [H]C1=C([H])C(I)=C([H])C(*)=C1[H] 0.000 claims 2
- NQRYJNQNLNOLGT-UHFFFAOYSA-N Piperidine Chemical compound C1CCNCC1 NQRYJNQNLNOLGT-UHFFFAOYSA-N 0.000 claims 2
- 241000191967 Staphylococcus aureus Species 0.000 claims 2
- 238000004519 manufacturing process Methods 0.000 claims 2
- 208000035143 Bacterial infection Diseases 0.000 claims 1
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 claims 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 claims 1
- 208000022362 bacterial infectious disease Diseases 0.000 claims 1
- 239000002775 capsule Substances 0.000 claims 1
- 239000003795 chemical substances by application Substances 0.000 claims 1
- 239000008298 dragée Substances 0.000 claims 1
- 229940079593 drug Drugs 0.000 claims 1
- 230000000694 effects Effects 0.000 claims 1
- 239000000839 emulsion Substances 0.000 claims 1
- 150000002148 esters Chemical class 0.000 claims 1
- 239000008187 granular material Substances 0.000 claims 1
- 239000004530 micro-emulsion Substances 0.000 claims 1
- 239000006187 pill Substances 0.000 claims 1
- 239000000843 powder Substances 0.000 claims 1
- 230000002265 prevention Effects 0.000 claims 1
- 229940002612 prodrug Drugs 0.000 claims 1
- 239000000651 prodrug Substances 0.000 claims 1
- 150000003839 salts Chemical class 0.000 claims 1
- 239000000243 solution Substances 0.000 claims 1
- 239000012453 solvate Substances 0.000 claims 1
- 239000007921 spray Substances 0.000 claims 1
- 239000000829 suppository Substances 0.000 claims 1
- 239000000725 suspension Substances 0.000 claims 1
- 239000006188 syrup Substances 0.000 claims 1
- 235000020357 syrup Nutrition 0.000 claims 1
- 239000003826 tablet Substances 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US51223400A | 2000-02-24 | 2000-02-24 | |
| PCT/US2001/006006 WO2001063539A2 (en) | 2000-02-24 | 2001-02-23 | Anti-infective agents useful against multidrug-resistant strains of bacteria |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2004501865A JP2004501865A (ja) | 2004-01-22 |
| JP2004501865A5 true JP2004501865A5 (https=) | 2005-02-03 |
| JP4025548B2 JP4025548B2 (ja) | 2007-12-19 |
Family
ID=24038243
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2001562429A Expired - Fee Related JP4025548B2 (ja) | 2000-02-24 | 2001-02-23 | 多薬剤耐性菌株に対して有用な抗感染症薬 |
Country Status (9)
| Country | Link |
|---|---|
| EP (1) | EP1259923B1 (https=) |
| JP (1) | JP4025548B2 (https=) |
| AT (1) | ATE312839T1 (https=) |
| CA (1) | CA2398848C (https=) |
| DE (1) | DE60115851T2 (https=) |
| DK (1) | DK1259923T3 (https=) |
| ES (1) | ES2254389T3 (https=) |
| MX (1) | MXPA02008274A (https=) |
| WO (1) | WO2001063539A2 (https=) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0127349D0 (en) | 2001-11-14 | 2002-01-02 | Glaxo Group Ltd | Macrolides |
| WO2003090761A1 (en) * | 2002-04-25 | 2003-11-06 | Abbott Laboratories | 9-oxime macrolide antibacterials |
| GB0225384D0 (en) | 2002-10-31 | 2002-12-11 | Glaxo Group Ltd | Novel compounds |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8506380D0 (en) * | 1985-03-12 | 1985-04-11 | Beecham Group Plc | Chemical compounds |
| IL114589A (en) * | 1990-11-21 | 1999-12-22 | Roussel Uclaf | Intermediates for the preparation of erythromycin derivatives |
| CA2253338C (en) * | 1996-05-07 | 2007-05-08 | Abbott Laboratories | 6-o-substituted erythromycins and method for making them |
| AR023264A1 (es) * | 1999-04-08 | 2002-09-04 | Hokuriku Pharmaceutical | Derivados de eritromicina |
-
2001
- 2001-02-23 ES ES01920147T patent/ES2254389T3/es not_active Expired - Lifetime
- 2001-02-23 DK DK01920147T patent/DK1259923T3/da active
- 2001-02-23 MX MXPA02008274A patent/MXPA02008274A/es active IP Right Grant
- 2001-02-23 AT AT01920147T patent/ATE312839T1/de not_active IP Right Cessation
- 2001-02-23 JP JP2001562429A patent/JP4025548B2/ja not_active Expired - Fee Related
- 2001-02-23 CA CA002398848A patent/CA2398848C/en not_active Expired - Fee Related
- 2001-02-23 EP EP01920147A patent/EP1259923B1/en not_active Expired - Lifetime
- 2001-02-23 WO PCT/US2001/006006 patent/WO2001063539A2/en not_active Ceased
- 2001-02-23 DE DE60115851T patent/DE60115851T2/de not_active Expired - Fee Related
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