JP2004501724A5 - - Google Patents
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- Publication number
- JP2004501724A5 JP2004501724A5 JP2002506799A JP2002506799A JP2004501724A5 JP 2004501724 A5 JP2004501724 A5 JP 2004501724A5 JP 2002506799 A JP2002506799 A JP 2002506799A JP 2002506799 A JP2002506799 A JP 2002506799A JP 2004501724 A5 JP2004501724 A5 JP 2004501724A5
- Authority
- JP
- Japan
- Prior art keywords
- needle
- substance
- outlet
- skin
- depth
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000000126 substance Substances 0.000 description 20
- 238000000034 method Methods 0.000 description 8
- 230000035515 penetration Effects 0.000 description 5
- 208000002193 Pain Diseases 0.000 description 2
- 208000007536 Thrombosis Diseases 0.000 description 2
- ZYGHJZDHTFUPRJ-UHFFFAOYSA-N coumarin Chemical compound C1=CC=C2OC(=O)C=CC2=C1 ZYGHJZDHTFUPRJ-UHFFFAOYSA-N 0.000 description 2
- 239000005556 hormone Substances 0.000 description 2
- 229940088597 hormone Drugs 0.000 description 2
- 208000015181 infectious disease Diseases 0.000 description 2
- 239000007788 liquid Substances 0.000 description 2
- 230000036407 pain Effects 0.000 description 2
- 230000002265 prevention Effects 0.000 description 2
- ZISSAWUMDACLOM-UHFFFAOYSA-N triptane Chemical compound CC(C)C(C)(C)C ZISSAWUMDACLOM-UHFFFAOYSA-N 0.000 description 2
- HTTJABKRGRZYRN-UHFFFAOYSA-N Heparin Chemical compound OC1C(NC(=O)C)C(O)OC(COS(O)(=O)=O)C1OC1C(OS(O)(=O)=O)C(O)C(OC2C(C(OS(O)(=O)=O)C(OC3C(C(O)C(O)C(O3)C(O)=O)OS(O)(=O)=O)C(CO)O2)NS(O)(=O)=O)C(C(O)=O)O1 HTTJABKRGRZYRN-UHFFFAOYSA-N 0.000 description 1
- 230000003444 anaesthetic effect Effects 0.000 description 1
- 230000000202 analgesic effect Effects 0.000 description 1
- 239000003242 anti bacterial agent Substances 0.000 description 1
- 230000001147 anti-toxic effect Effects 0.000 description 1
- -1 antitoxins Substances 0.000 description 1
- 230000003115 biocidal effect Effects 0.000 description 1
- 238000004891 communication Methods 0.000 description 1
- 229960000956 coumarin Drugs 0.000 description 1
- 235000001671 coumarin Nutrition 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 230000008030 elimination Effects 0.000 description 1
- 238000003379 elimination reaction Methods 0.000 description 1
- 238000001125 extrusion Methods 0.000 description 1
- 239000012530 fluid Substances 0.000 description 1
- 229960002897 heparin Drugs 0.000 description 1
- 229920000669 heparin Polymers 0.000 description 1
- 230000036039 immunity Effects 0.000 description 1
- 238000002347 injection Methods 0.000 description 1
- 239000007924 injection Substances 0.000 description 1
- NOESYZHRGYRDHS-UHFFFAOYSA-N insulin Substances N1C(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(NC(=O)CN)C(C)CC)CSSCC(C(NC(CO)C(=O)NC(CC(C)C)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CCC(N)=O)C(=O)NC(CC(C)C)C(=O)NC(CCC(O)=O)C(=O)NC(CC(N)=O)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CSSCC(NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2C=CC(O)=CC=2)NC(=O)C(CC(C)C)NC(=O)C(C)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2NC=NC=2)NC(=O)C(CO)NC(=O)CNC2=O)C(=O)NCC(=O)NC(CCC(O)=O)C(=O)NC(CCCNC(N)=N)C(=O)NCC(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC(O)=CC=3)C(=O)NC(C(C)O)C(=O)N3C(CCC3)C(=O)NC(CCCCN)C(=O)NC(C)C(O)=O)C(=O)NC(CC(N)=O)C(O)=O)=O)NC(=O)C(C(C)CC)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C1CSSCC2NC(=O)C(CC(C)C)NC(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C(N)CC=1C=CC=CC=1)C(C)C)CC1=CN=CN1 NOESYZHRGYRDHS-UHFFFAOYSA-N 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 239000000199 parathyroid hormone Substances 0.000 description 1
- 230000001681 protective effect Effects 0.000 description 1
- 238000007789 sealing Methods 0.000 description 1
- 230000008961 swelling Effects 0.000 description 1
- 230000001988 toxicity Effects 0.000 description 1
- 231100000419 toxicity Toxicity 0.000 description 1
- 229960005486 vaccine Drugs 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/606,909 US8465468B1 (en) | 2000-06-29 | 2000-06-29 | Intradermal delivery of substances |
| US09/606,909 | 2000-06-29 | ||
| PCT/US2001/020763 WO2002002178A1 (en) | 2000-06-29 | 2001-06-29 | Needle for intradermal delivery of substances having penetration limiting means |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2004501724A JP2004501724A (ja) | 2004-01-22 |
| JP2004501724A5 true JP2004501724A5 (enExample) | 2008-08-21 |
| JP5614911B2 JP5614911B2 (ja) | 2014-10-29 |
Family
ID=24430006
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2002506800A Pending JP2004501725A (ja) | 2000-06-29 | 2001-06-29 | 真皮へと物質を送達するためのマイクロニードル |
| JP2002506799A Expired - Lifetime JP5614911B2 (ja) | 2000-06-29 | 2001-06-29 | 貫通制限手段を有する、物質の皮内送達のためのニードル |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2002506800A Pending JP2004501725A (ja) | 2000-06-29 | 2001-06-29 | 真皮へと物質を送達するためのマイクロニードル |
Country Status (16)
| Country | Link |
|---|---|
| US (13) | US8465468B1 (enExample) |
| EP (5) | EP1925333B1 (enExample) |
| JP (2) | JP2004501725A (enExample) |
| KR (2) | KR100897148B1 (enExample) |
| CN (2) | CN1454104A (enExample) |
| AT (4) | ATE536906T1 (enExample) |
| AU (6) | AU2001270262B2 (enExample) |
| BR (2) | BR0112314A (enExample) |
| CA (2) | CA2413798C (enExample) |
| CY (3) | CY1107458T1 (enExample) |
| DE (3) | DE60134286D1 (enExample) |
| DK (4) | DK1296740T3 (enExample) |
| ES (4) | ES2303169T3 (enExample) |
| MX (2) | MXPA03000228A (enExample) |
| PT (3) | PT1625870E (enExample) |
| WO (2) | WO2002002179A1 (enExample) |
Families Citing this family (105)
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| US6797276B1 (en) | 1996-11-14 | 2004-09-28 | The United States Of America As Represented By The Secretary Of The Army | Use of penetration enhancers and barrier disruption agents to enhance the transcutaneous immune response |
| US20060002949A1 (en) | 1996-11-14 | 2006-01-05 | Army Govt. Of The Usa, As Rep. By Secretary Of The Office Of The Command Judge Advocate, Hq Usamrmc. | Transcutaneous immunization without heterologous adjuvant |
| US5980898A (en) | 1996-11-14 | 1999-11-09 | The United States Of America As Represented By The U.S. Army Medical Research & Material Command | Adjuvant for transcutaneous immunization |
| US20020095134A1 (en) * | 1999-10-14 | 2002-07-18 | Pettis Ronald J. | Method for altering drug pharmacokinetics based on medical delivery platform |
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| US20050008683A1 (en) * | 2000-06-29 | 2005-01-13 | Becton Dickinson And Company | Method for delivering interferons to the intradermal compartment |
| US20040175360A1 (en) * | 2000-06-29 | 2004-09-09 | Pettis Ronald J. | Method for altering drug pharmacokinetics based on medical delivery platform |
| PT1372708E (pt) | 2001-02-13 | 2008-09-29 | Us Gov Sec Army | Vacina para imunização transcutânea |
| CA2438942A1 (en) * | 2001-02-23 | 2002-09-26 | Glaxosmithkline Biologicals S.A. | Influenza vaccine formulations for intradermal delivery |
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2000
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2001
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