JP2004137245A - ピラゾール誘導体、それを含有する医薬組成物、その医薬用途及びその製造中間体 - Google Patents
ピラゾール誘導体、それを含有する医薬組成物、その医薬用途及びその製造中間体 Download PDFInfo
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- JP2004137245A JP2004137245A JP2002324076A JP2002324076A JP2004137245A JP 2004137245 A JP2004137245 A JP 2004137245A JP 2002324076 A JP2002324076 A JP 2002324076A JP 2002324076 A JP2002324076 A JP 2002324076A JP 2004137245 A JP2004137245 A JP 2004137245A
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Priority Applications (19)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2002324076A JP2004137245A (ja) | 2002-08-23 | 2002-11-07 | ピラゾール誘導体、それを含有する医薬組成物、その医薬用途及びその製造中間体 |
| PCT/JP2003/010551 WO2004018491A1 (ja) | 2002-08-23 | 2003-08-21 | ピラゾール誘導体、それを含有する医薬組成物、その医薬用途及びその製造中間体 |
| BRPI0313694A BRPI0313694B8 (pt) | 2002-08-23 | 2003-08-21 | derivados de pirazol, composição medicinal contendo os mesmos, seu uso medicinal e intermediários para sua produção |
| JP2005501231A JP4597048B2 (ja) | 2002-08-23 | 2003-08-21 | ピラゾール誘導体、それを含有する医薬組成物、その医薬用途及びその製造中間体 |
| MXPA05002129A MXPA05002129A (es) | 2002-08-23 | 2003-08-21 | Derivados de pirazol composicion medicinal que los contiene, su uso en medicina, e intermediarios para su produccion. |
| RU2005108055/04A RU2369613C2 (ru) | 2002-08-23 | 2003-08-21 | Производные пиразола, медицинские композиции, содержащие их, их применение в медицине и промежуточные соединения для их получения |
| PL375551A PL213094B1 (pl) | 2002-08-23 | 2003-08-21 | Pochodna pirazolowa, kompozycja farmaceutyczna, srodek do zapobiegania lub leczenia choroby oraz zastosowanie pochodnej pirazolowej |
| EP03792760A EP1548024B1 (en) | 2002-08-23 | 2003-08-21 | Pyrazole derivatives, medicinal composition containing the same, medicinal use thereof, and intermediate for production thereof |
| US10/525,197 US7635684B2 (en) | 2002-08-23 | 2003-08-21 | Pyrazole derivatives, medicinal composition containing the same, medicinal use thereof, and intermediate for production thereof |
| NZ538423A NZ538423A (en) | 2002-08-23 | 2003-08-21 | Medicinal composition and use of pyrazole derivatives with human SGLT1 inhibitory activity useful in treatment of hyperglycemic diseases |
| HK06102573.5A HK1082744B (en) | 2002-08-23 | 2003-08-21 | Pyrazole derivatives, medicinal composition containing the same, medicinal use thereof, and intermediate for production thereof |
| AU2003262263A AU2003262263B8 (en) | 2002-08-23 | 2003-08-21 | Pyrazole derivatives, medicinal composition containing the same, medicinal use thereof, and intermediate for production thereof |
| ES03792760T ES2386140T3 (es) | 2002-08-23 | 2003-08-21 | Derivados de pirazol, composición medicinal que contiene los mismos, uso medicinal de los mismos e intermedio para la producción de los mismos |
| KR1020057003117A KR100985504B1 (ko) | 2002-08-23 | 2003-08-21 | 피라졸 유도체, 그것을 함유하는 의약조성물, 그 의약용도및 그 제조중간체 |
| CA2496329A CA2496329C (en) | 2002-08-23 | 2003-08-21 | Pyrazole derivatives, medicinal composition containing the same, medicinal use thereof, and intermediate for production thereof |
| TW092123126A TW200410980A (en) | 2002-08-23 | 2003-08-22 | Pyrazole derivatives, medicinal composition containing the same, medicinal use thereof, and intermediate for production thereof |
| IL167038A IL167038A (en) | 2002-08-23 | 2005-02-22 | Pyrazole derivatives, pharmaceutical compositions containing the same, use thereof in the manufacture of medicaments and intermediate for production thereof |
| NO20051411A NO330569B1 (no) | 2002-08-23 | 2005-03-17 | Pyrazolderivater, medisinske sammensetninger inneholdende slike, medisinsk bruk derav samt intermediater til fremstilling derav |
| US12/421,236 US8324176B2 (en) | 2002-08-23 | 2009-04-09 | Pyrazole derivatives, medicinal composition containing the same, medicinal use thereof, and intermediate for production thereof |
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2002244381 | 2002-08-23 | ||
| JP2002324076A JP2004137245A (ja) | 2002-08-23 | 2002-11-07 | ピラゾール誘導体、それを含有する医薬組成物、その医薬用途及びその製造中間体 |
Publications (1)
| Publication Number | Publication Date |
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| JP2004137245A true JP2004137245A (ja) | 2004-05-13 |
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| Application Number | Title | Priority Date | Filing Date |
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| JP2002324076A Pending JP2004137245A (ja) | 2002-08-23 | 2002-11-07 | ピラゾール誘導体、それを含有する医薬組成物、その医薬用途及びその製造中間体 |
| JP2005501231A Expired - Lifetime JP4597048B2 (ja) | 2002-08-23 | 2003-08-21 | ピラゾール誘導体、それを含有する医薬組成物、その医薬用途及びその製造中間体 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
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| JP2005501231A Expired - Lifetime JP4597048B2 (ja) | 2002-08-23 | 2003-08-21 | ピラゾール誘導体、それを含有する医薬組成物、その医薬用途及びその製造中間体 |
Country Status (16)
| Country | Link |
|---|---|
| US (2) | US7635684B2 (enExample) |
| EP (1) | EP1548024B1 (enExample) |
| JP (2) | JP2004137245A (enExample) |
| KR (1) | KR100985504B1 (enExample) |
| AU (1) | AU2003262263B8 (enExample) |
| BR (1) | BRPI0313694B8 (enExample) |
| CA (1) | CA2496329C (enExample) |
| ES (1) | ES2386140T3 (enExample) |
| IL (1) | IL167038A (enExample) |
| MX (1) | MXPA05002129A (enExample) |
| NO (1) | NO330569B1 (enExample) |
| NZ (1) | NZ538423A (enExample) |
| PL (1) | PL213094B1 (enExample) |
| RU (1) | RU2369613C2 (enExample) |
| TW (1) | TW200410980A (enExample) |
| WO (1) | WO2004018491A1 (enExample) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPWO2004019958A1 (ja) * | 2002-08-27 | 2005-12-15 | キッセイ薬品工業株式会社 | ピラゾール誘導体、それを含有する医薬組成物及びその医薬用途 |
| WO2006062224A1 (ja) * | 2004-12-07 | 2006-06-15 | Takeda Pharmaceutical Company Limited | カルボキサミド誘導体 |
| JP2008501745A (ja) * | 2004-06-11 | 2008-01-24 | サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング | ピラゾールの新規フルオログリコシド誘導体、これらの化合物を含有する医薬、及びその使用 |
Families Citing this family (52)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ538117A (en) * | 2002-08-08 | 2007-01-26 | Kissei Pharmaceutical | Pyrazole derivative, medicinal composition containing the same, medicinal use thereof, and intermediate for production thereof |
| JP2004137245A (ja) | 2002-08-23 | 2004-05-13 | Kissei Pharmaceut Co Ltd | ピラゾール誘導体、それを含有する医薬組成物、その医薬用途及びその製造中間体 |
| WO2004050122A1 (ja) * | 2002-12-04 | 2004-06-17 | Kissei Pharmaceutical Co., Ltd. | 高血糖症に起因する疾患の予防又は治療剤 |
| AU2003289440A1 (en) * | 2002-12-25 | 2004-07-22 | Kissei Pharmaceutical Co., Ltd. | Nitrogen-containing heterocycic derivatives, medicinal compositions containing the same and medicinal use thereof |
| US7375090B2 (en) * | 2003-08-26 | 2008-05-20 | Boehringer Ingelheim International Gmbh | Glucopyranosyloxy-pyrazoles, pharmaceutical compositions containing these compounds, the use thereof and processed for the preparation thereof |
| US7838552B2 (en) | 2004-06-04 | 2010-11-23 | Forest Laboratories Holdings Limited | Compositions comprising nebivolol |
| US7803838B2 (en) | 2004-06-04 | 2010-09-28 | Forest Laboratories Holdings Limited | Compositions comprising nebivolol |
| WO2006054629A1 (ja) | 2004-11-18 | 2006-05-26 | Kissei Pharmaceutical Co., Ltd. | １－置換－３－（β－Ｄ－グリコピラノシル）含窒素ヘテロ環化合物、及びそれを含有する医薬 |
| WO2007010015A1 (en) * | 2005-07-22 | 2007-01-25 | Boehringer Ingelheim International Gmbh | Processes for preparing pyrazole-o-glycoside derivatives and novel intermediates of said processes |
| UY30082A1 (es) | 2006-01-11 | 2007-08-31 | Boehringer Ingelheim Int | Forma cristalina de 1-(1-metiletil)-4`-((2-fluoro-4-metoxifenil)metil)-5`- metil-1h-pirazol-3`-o-b-d-glucopiranosido, un metodo para su preparacion y el uso de la misma para preparar medicamentos |
| JP2009167103A (ja) * | 2006-05-02 | 2009-07-30 | Taisho Pharmaceutical Co Ltd | ピラゾリル５−チオグリコシド化合物 |
| PE20080251A1 (es) | 2006-05-04 | 2008-04-25 | Boehringer Ingelheim Int | Usos de inhibidores de dpp iv |
| AR061026A1 (es) | 2006-05-19 | 2008-07-30 | Taisho Pharmaceutical Co Ltd | Compuesto glicitol c-fenilo y preparacion farmaceutica |
| CN101479254B (zh) | 2006-06-29 | 2012-05-30 | 大正制药株式会社 | C-苯基1-硫代山梨醇化合物 |
| AU2007332476A1 (en) | 2006-12-14 | 2008-06-19 | Taisho Pharmaceutical Co., Ltd. | 1-phenyl 1-thio-D-glucitol derivative |
| NZ586336A (en) | 2007-12-27 | 2011-06-30 | Kissei Pharmaceutical | Monosebacate of pyrazole derivative |
| US8354382B2 (en) | 2008-04-16 | 2013-01-15 | Kissei Pharmaceutical Co., Ltd. | Hemifumarate of a pyrazole derivative |
| ATE540040T1 (de) | 2008-08-28 | 2012-01-15 | Pfizer | Dioxabicycloä3.2.1üoctan-2,3,4-triolderivate |
| MY155658A (en) * | 2009-02-23 | 2015-11-13 | Taisho Pharmaceutical Co Ltd | A-isopropylphenyl glucitol compounds as sglti inhibitors |
| JPWO2011002001A1 (ja) * | 2009-07-01 | 2012-12-13 | キッセイ薬品工業株式会社 | ピラゾール誘導体とビグアナイド薬との組み合わせ医薬 |
| WO2011002011A1 (ja) * | 2009-07-01 | 2011-01-06 | キッセイ薬品工業株式会社 | Sglt1阻害薬とdpp-iv阻害薬を組み合わせてなる医薬 |
| TW201105337A (en) * | 2009-07-01 | 2011-02-16 | Dainippon Sumitomo Pharma Co | Medicine derived from a combination of SGLT1-inhibitor and insulin sensitizer |
| CN102574776A (zh) | 2009-07-31 | 2012-07-11 | 桑多斯股份公司 | ω-氨基-烷酰胺和ω-氨基-烷硫酰胺的制备方法及该方法的中间体 |
| EP2298782A1 (en) * | 2009-08-26 | 2011-03-23 | Sanofi-Aventis | Method for producing pyrazole glycoside derivatives |
| US20120270819A1 (en) | 2009-10-02 | 2012-10-25 | Sanofi | Use of compounds with sglt-1/sglt-2 inhibitor activity for producing medicaments for treatment of bone disease |
| WO2011048148A2 (en) | 2009-10-20 | 2011-04-28 | Novartis Ag | Glycoside derivative and uses thereof |
| US8163704B2 (en) | 2009-10-20 | 2012-04-24 | Novartis Ag | Glycoside derivatives and uses thereof |
| ME02016B (me) | 2009-11-02 | 2015-05-20 | Pfizer | Derivati dioksabiciklo[3.2.1]oktan-2,3,4-triola |
| WO2011107494A1 (de) | 2010-03-03 | 2011-09-09 | Sanofi | Neue aromatische glykosidderivate, diese verbindungen enthaltende arzneimittel und deren verwendung |
| WO2012010651A2 (en) | 2010-07-23 | 2012-01-26 | Sandoz Ag | Method for the preparation of omega-amino-alkaneamides and omega-amino-alkanethioamides as well as intermediates of this method |
| EP2607360B1 (en) | 2010-08-20 | 2015-08-19 | Taisho Pharmaceutical Co., Ltd. | 4-Isopropyl-6-methoxyphenyl glucitol compound |
| JP5656092B2 (ja) | 2010-08-20 | 2015-01-21 | 大正製薬株式会社 | ４−イソプロピルフェニルグルシトール化合物の結晶形及びその製造方法 |
| US8614195B2 (en) | 2011-04-14 | 2013-12-24 | Novartis Ag | Glycoside derivatives and uses thereof |
| BR112013026361A2 (pt) | 2011-04-14 | 2016-12-27 | Novartis Ag | derivados de glicosídeo e usos dos mesmos |
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| CA2872002C (en) | 2012-05-07 | 2019-01-15 | Masayuki Isaji | Pyrazole derivative and use thereof for medical purposes |
| UA113086C2 (xx) | 2012-05-10 | 2016-12-12 | Піразольні сполуки як інгібітори sglt1 | |
| TW201425326A (zh) * | 2012-10-05 | 2014-07-01 | Lilly Co Eli | 新穎脲化合物 |
| RU2015123738A (ru) | 2012-11-20 | 2017-01-10 | Лексикон Фармасьютикалз, Инк. | Ингибиторы котранспортера натрий-глюкозы 1 |
| RU2648467C2 (ru) | 2013-02-04 | 2018-03-26 | Тайсо Фармасьютикал Ко., Лтд. | Профилактическое или терапевтическое лекарственное средство для лечения запора |
| EP2774619B1 (de) | 2013-03-04 | 2016-05-18 | BioActive Food GmbH | Zusammensetzung zur Behandlung von hyperglykämischen Erkrankungen |
| US8652527B1 (en) | 2013-03-13 | 2014-02-18 | Upsher-Smith Laboratories, Inc | Extended-release topiramate capsules |
| US9101545B2 (en) | 2013-03-15 | 2015-08-11 | Upsher-Smith Laboratories, Inc. | Extended-release topiramate capsules |
| AR098670A1 (es) | 2013-11-08 | 2016-06-08 | Lilly Co Eli | Inhibidor de sglt1 |
| EP2944311A1 (de) | 2014-05-16 | 2015-11-18 | BioActive Food GmbH | Kombination von biologisch aktiven Substanzen zur Behandlung von hyperglykämischen Erkrankungen |
| US11186602B2 (en) | 2018-01-31 | 2021-11-30 | Sunshine Lake Pharma Co., Ltd. | Glucopyranosyl derivative and use thereof |
| MX2020009349A (es) | 2018-03-28 | 2021-04-28 | Avolynt | Método para el tratamiento de la hipoglucemia posprandial. |
| EP3886854A4 (en) | 2018-11-30 | 2022-07-06 | Nuvation Bio Inc. | Pyrrole and pyrazole compounds and methods of use thereof |
| BR112021024165A2 (pt) * | 2019-05-31 | 2022-04-26 | Avolynt | Composições e métodos para o tratamento de doenças metabólicas |
| WO2024254354A1 (en) * | 2023-06-06 | 2024-12-12 | Vogenx | Compositions and methods for treating refractory or intractable epilepsy |
| WO2024254302A1 (en) * | 2023-06-06 | 2024-12-12 | Vogenx | Compositions and methods for treating hyperinsulinemic hypoglycemia |
| WO2025117962A1 (en) * | 2023-12-01 | 2025-06-05 | Vogenx | Compositions and methods for treating glucose-dependent insulinotropic peptide-dependent cushing's syndrome |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2219172C2 (ru) * | 1999-04-06 | 2003-12-20 | Санкио Компани, Лимитед | α-ЗАМЕЩЕННЫЕ ПРОИЗВОДНЫЕ КАРБОНОВЫХ КИСЛОТ |
| CA2382480C (en) * | 1999-08-31 | 2008-09-30 | Kissei Pharmaceutical Co., Ltd. | Glucopyranosyloxypyrazole derivatives, medicinal compositions containing the same and intermediates in the production thereof |
| EP2163555A1 (en) * | 2000-11-02 | 2010-03-17 | Ajinomoto Co., Inc. | New pyrazole derivatives and diabetic medicine containing them |
| SK287786B6 (sk) * | 2000-12-28 | 2011-09-05 | Kissei Pharmaceutical Co., Ltd. | Glukopyranosyloxypyrazolový derivát, farmaceutická kompozícia alebo kombinácia s jeho obsahom a ich použitie |
| NZ538117A (en) * | 2002-08-08 | 2007-01-26 | Kissei Pharmaceutical | Pyrazole derivative, medicinal composition containing the same, medicinal use thereof, and intermediate for production thereof |
| JP2004137245A (ja) | 2002-08-23 | 2004-05-13 | Kissei Pharmaceut Co Ltd | ピラゾール誘導体、それを含有する医薬組成物、その医薬用途及びその製造中間体 |
| WO2004031203A1 (ja) * | 2002-10-04 | 2004-04-15 | Kissei Pharmaceutical Co., Ltd. | ピラゾール誘導体、それを含有する医薬組成物、その医薬用途及びその製造中間体 |
| US7576064B2 (en) * | 2003-06-20 | 2009-08-18 | Kissei Pharmaceutical Co., Ltd. | Pyrazole derivative, drug composition containing the same and production intermediate therefor |
-
2002
- 2002-11-07 JP JP2002324076A patent/JP2004137245A/ja active Pending
-
2003
- 2003-08-21 KR KR1020057003117A patent/KR100985504B1/ko not_active Expired - Lifetime
- 2003-08-21 MX MXPA05002129A patent/MXPA05002129A/es active IP Right Grant
- 2003-08-21 WO PCT/JP2003/010551 patent/WO2004018491A1/ja not_active Ceased
- 2003-08-21 ES ES03792760T patent/ES2386140T3/es not_active Expired - Lifetime
- 2003-08-21 PL PL375551A patent/PL213094B1/pl unknown
- 2003-08-21 US US10/525,197 patent/US7635684B2/en active Active
- 2003-08-21 BR BRPI0313694A patent/BRPI0313694B8/pt not_active IP Right Cessation
- 2003-08-21 RU RU2005108055/04A patent/RU2369613C2/ru active
- 2003-08-21 CA CA2496329A patent/CA2496329C/en not_active Expired - Lifetime
- 2003-08-21 JP JP2005501231A patent/JP4597048B2/ja not_active Expired - Lifetime
- 2003-08-21 NZ NZ538423A patent/NZ538423A/en not_active IP Right Cessation
- 2003-08-21 AU AU2003262263A patent/AU2003262263B8/en not_active Expired
- 2003-08-21 EP EP03792760A patent/EP1548024B1/en not_active Expired - Lifetime
- 2003-08-22 TW TW092123126A patent/TW200410980A/zh not_active IP Right Cessation
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2005
- 2005-02-22 IL IL167038A patent/IL167038A/en unknown
- 2005-03-17 NO NO20051411A patent/NO330569B1/no not_active IP Right Cessation
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2009
- 2009-04-09 US US12/421,236 patent/US8324176B2/en not_active Expired - Lifetime
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPWO2004019958A1 (ja) * | 2002-08-27 | 2005-12-15 | キッセイ薬品工業株式会社 | ピラゾール誘導体、それを含有する医薬組成物及びその医薬用途 |
| JP4606876B2 (ja) * | 2002-08-27 | 2011-01-05 | キッセイ薬品工業株式会社 | ピラゾール誘導体、それを含有する医薬組成物及びその医薬用途 |
| JP2008501745A (ja) * | 2004-06-11 | 2008-01-24 | サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング | ピラゾールの新規フルオログリコシド誘導体、これらの化合物を含有する医薬、及びその使用 |
| WO2006062224A1 (ja) * | 2004-12-07 | 2006-06-15 | Takeda Pharmaceutical Company Limited | カルボキサミド誘導体 |
Also Published As
| Publication number | Publication date |
|---|---|
| KR20050038633A (ko) | 2005-04-27 |
| EP1548024A1 (en) | 2005-06-29 |
| NO20051411L (no) | 2005-04-26 |
| BRPI0313694B8 (pt) | 2021-05-25 |
| NZ538423A (en) | 2007-02-23 |
| AU2003262263B2 (en) | 2009-06-25 |
| BRPI0313694B1 (pt) | 2017-12-19 |
| PL375551A1 (en) | 2005-11-28 |
| MXPA05002129A (es) | 2005-06-03 |
| US8324176B2 (en) | 2012-12-04 |
| JPWO2004018491A1 (ja) | 2005-12-08 |
| KR100985504B1 (ko) | 2010-10-05 |
| RU2369613C2 (ru) | 2009-10-10 |
| AU2003262263B8 (en) | 2009-08-06 |
| TW200410980A (en) | 2004-07-01 |
| RU2005108055A (ru) | 2006-02-10 |
| JP4597048B2 (ja) | 2010-12-15 |
| HK1082744A1 (zh) | 2006-06-16 |
| IL167038A (en) | 2010-11-30 |
| US20090203633A1 (en) | 2009-08-13 |
| TWI298071B (enExample) | 2008-06-21 |
| EP1548024A4 (en) | 2010-05-12 |
| US7635684B2 (en) | 2009-12-22 |
| BR0313694A (pt) | 2005-07-05 |
| AU2003262263A1 (en) | 2004-03-11 |
| WO2004018491A1 (ja) | 2004-03-04 |
| PL213094B1 (pl) | 2013-01-31 |
| CA2496329A1 (en) | 2004-03-04 |
| NO330569B1 (no) | 2011-05-16 |
| CA2496329C (en) | 2012-05-15 |
| EP1548024B1 (en) | 2012-06-06 |
| ES2386140T3 (es) | 2012-08-10 |
| US20050272669A1 (en) | 2005-12-08 |
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