JP2004115525A - 抗炎症性化合物の局所搬送用搬送剤 - Google Patents

抗炎症性化合物の局所搬送用搬送剤 Download PDF

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Publication number
JP2004115525A
JP2004115525A JP2003338818A JP2003338818A JP2004115525A JP 2004115525 A JP2004115525 A JP 2004115525A JP 2003338818 A JP2003338818 A JP 2003338818A JP 2003338818 A JP2003338818 A JP 2003338818A JP 2004115525 A JP2004115525 A JP 2004115525A
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Japan
Prior art keywords
menthol
composition
camphor
carrier according
emulsion
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
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JP2003338818A
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English (en)
Japanese (ja)
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JP2004115525A5 (enrdf_load_stackoverflow
Inventor
Joseph Schwarz
シュワルツ,ジョセフ
Michael Weisspapir
ワイスパピア,マイケル
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Alpharx Inc
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Alpharx Inc
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Publication date
Application filed by Alpharx Inc filed Critical Alpharx Inc
Publication of JP2004115525A publication Critical patent/JP2004115525A/ja
Publication of JP2004115525A5 publication Critical patent/JP2004115525A5/ja
Pending legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/045Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/05Phenols
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/12Ketones
    • A61K31/122Ketones having the oxygen directly attached to a ring, e.g. quinones, vitamin K1, anthralin
    • A61K31/125Camphor; Nuclear substituted derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Organic Chemistry (AREA)
  • Dermatology (AREA)
  • Pain & Pain Management (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Rheumatology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2003338818A 2002-09-27 2003-09-29 抗炎症性化合物の局所搬送用搬送剤 Pending JP2004115525A (ja)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US10/255,951 US7138394B2 (en) 2002-09-27 2002-09-27 Vehicle for topical delivery of anti-inflammatory compounds

Publications (2)

Publication Number Publication Date
JP2004115525A true JP2004115525A (ja) 2004-04-15
JP2004115525A5 JP2004115525A5 (enrdf_load_stackoverflow) 2007-02-01

Family

ID=32029201

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2003338818A Pending JP2004115525A (ja) 2002-09-27 2003-09-29 抗炎症性化合物の局所搬送用搬送剤

Country Status (4)

Country Link
US (3) US7138394B2 (enrdf_load_stackoverflow)
JP (1) JP2004115525A (enrdf_load_stackoverflow)
CN (1) CN100534530C (enrdf_load_stackoverflow)
MX (1) MXPA03008947A (enrdf_load_stackoverflow)

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2008013449A (ja) * 2006-07-04 2008-01-24 Taisho Pharmaceut Co Ltd ユビデカレノン含有自己乳化組成物
JP2012523408A (ja) * 2009-04-08 2012-10-04 カディラ・ヘルスケア・リミテッド ジクロフェナクの安定な医薬組成物
WO2015151990A1 (ja) * 2014-03-30 2015-10-08 小林製薬株式会社 外用医薬組成物
JP2015189759A (ja) * 2014-03-30 2015-11-02 小林製薬株式会社 外用医薬組成物
JP2022500446A (ja) * 2018-09-17 2022-01-04 ソシエテ・デクスプロワタシオン・デ・プロデュイ・プール・レ・アンデュストリー・シミック・セピックSociete D’Exploitation De Produits Pour Les Industries Chimiques Seppic 少なくとも1つの抗炎症物質を含む局所使用のための医薬組成物
JP2024056733A (ja) * 2018-08-01 2024-04-23 ノビラ・ファーマシューティカルズ・インコーポレイテッド 薬剤を含む共晶溶媒、並びにその製造および使用方法

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060241175A1 (en) * 2002-09-27 2006-10-26 Joseph Schwarz Vehicle for topical delivery of anti-inflammatory compounds
US7138394B2 (en) * 2002-09-27 2006-11-21 Alpharx Inc. Vehicle for topical delivery of anti-inflammatory compounds
EP1858556A1 (en) * 2005-03-16 2007-11-28 Alpharx Inc. Vehicle for topical delivery of anti-inflammatory compounds
US20060240051A1 (en) * 2005-04-26 2006-10-26 Singleton Andy H Eutectic blends containing a water soluble vitamin derivative
AU2006243032A1 (en) * 2005-05-05 2006-11-09 Reckitt Benckiser Llc Topical compositions
US20070042007A1 (en) * 2005-08-19 2007-02-22 Joseph Schwarz Topical composition for delivery of salicylate esters
US20070048360A1 (en) * 2005-08-23 2007-03-01 R Carrara Dario N Pharmaceutical compositions with melting point depressant agents and method of making same
GT200600405A (es) * 2005-09-07 2007-04-16 Formula de microemulsión
AU2006330526B2 (en) * 2005-12-22 2012-09-27 Oakwood Laboratories, Llc Sublimable sustained release delivery system and method of making same
DE102006042742A1 (de) * 2006-09-12 2008-03-27 Barnikol-Keuten, Doris, Dr. Nano-Vehikel für den transkutanen Transport, diese enthaltende Zubereitungen und deren Anwendung
RU2463038C2 (ru) 2006-10-17 2012-10-10 Нуво Рисерч Инк. Диклофенаковый гель
HU227970B1 (en) * 2007-07-10 2012-07-30 Egis Gyogyszergyar Nyrt Pharmaceutical compositions containing silicones of high volatility
US8618164B2 (en) 2009-03-31 2013-12-31 Nuvo Research Inc. Treatment of pain with topical diclofenac compounds
CN101524325B (zh) * 2009-04-03 2010-12-29 龚志成 复方薄荷脑微乳及其鼻用制剂
CA2785643A1 (en) 2009-12-23 2011-06-30 Nuvo Research Inc. Highly permeating terbinafine formulation
DE102010013064A1 (de) 2010-03-26 2011-12-15 Gabriele Blume Neuartiges Trägersystem für den Transport von Wirkstoffen in die Haut
EP2457554A1 (de) * 2010-11-24 2012-05-30 Symrise AG Menthol enthaltende Mischung
US9545429B1 (en) 2011-09-03 2017-01-17 Biolyte Laboratories, Llc Homeopathic formulations
US11154535B2 (en) 2012-07-31 2021-10-26 Egis Pharmaceuticals Plc Transdermal formulation containing COX inhibitors
US10045965B2 (en) 2012-07-31 2018-08-14 Egis Pharmaceuticals Plc Transdermal formulation containing COX inhibitors
US10045935B2 (en) 2012-07-31 2018-08-14 Egis Pharmaceuticals Plc Transdermal formulation containing COX inhibitors
FR2994386B1 (fr) * 2012-08-07 2016-06-24 Thorel Jean-Noel Inhibition de l'adhesion de micro-organismes pathogenes par un ester de saccharose et/ou de sorbitan dans le traitement cosmetique de l'atopie cutanee
WO2014095257A1 (en) 2012-12-20 2014-06-26 Unilever N.V. Eutectic mixtures in personal care compositions
CN104884034B (zh) * 2012-12-20 2017-06-06 荷兰联合利华有限公司 个人护理组合物中的低共熔混合物
KR102187731B1 (ko) * 2013-02-01 2020-12-07 디드롭스 컴퍼니 액체 멘톨 조성물
US20160000803A1 (en) * 2013-02-22 2016-01-07 Eastgate Pharmaceuticals Inc. Pharmaceutical composition for transmucosal administration of benzodiazepines
CA2978517A1 (en) 2014-03-04 2015-09-11 Eastgate Pharmaceuticals Inc. Pharmaceutical composition for transmucosal delivery and methods for treating diabetes in a subject in need thereof
US9012402B1 (en) 2014-06-11 2015-04-21 James Blanchard Gel for topical delivery of NSAIDs to provide relief of musculoskeletal pain and methods for its preparation
US9623062B2 (en) * 2014-06-27 2017-04-18 Jeju National University Industryacademic Cooperation Foundation Anti-ageing activity of camphor in fibroblast cell line
US10828251B1 (en) 2017-01-14 2020-11-10 Biolyte Laboratories, Llc Homeopathic formulations
US10617634B1 (en) 2017-03-10 2020-04-14 Biolyte Laboratories, Llc Topical homeopathic formulations for menstrual cramps
US10821075B1 (en) 2017-07-12 2020-11-03 James Blanchard Compositions for topical application of a medicaments onto a mammalian body surface
BR102019014454A2 (pt) * 2018-07-13 2020-02-04 Upl Ltd composição compreendendo mistura eutética de fungicida boscalide e estrobilurina
AU2019363244B2 (en) 2018-10-15 2024-10-03 Cipla Limited Pharmaceutical formulation
WO2020188547A1 (en) * 2019-03-21 2020-09-24 Universidade Nova De Lisboa Terpene based therapeutic deep eutectic system, method of obtaining and uses thereof
WO2020223093A1 (en) * 2019-04-30 2020-11-05 Bayer Healthcare Llc Topical analgesic gel compositions
FR3099697B1 (fr) * 2019-08-09 2022-07-08 Soc Dexploitation De Produits Pour Les Industries Chimiques Seppic Composition pharmaceutique à usage topique se présentant sous la forme d’une phase dispersée à base d’au moins un diol court dans une phase grasse continue et comprenant au moins une substance anti-inflammatoire.
WO2022055927A1 (en) * 2020-09-11 2022-03-17 Ps Therapy Ltd. Topical compositions and methods of use
US20250099369A1 (en) 2023-09-27 2025-03-27 Andros Pharmaceuticals Co., Ltd. Topical delivery compositions comprising non-steroidal anti-inflammatory drugs
CN118084849B (zh) * 2024-01-22 2024-07-19 南京默可思泰医药科技有限公司 一种含有麝香草酚及其衍生物的胶束制剂的制备方法和应用

Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5562013A (en) * 1978-11-02 1980-05-10 Rakuule Yakuhin Hanbai Kk Aqueous poultice comprising transcutaneous absorbable anti-inflammatory agent
JPS58189115A (ja) * 1982-04-30 1983-11-04 Kowa Co 外用剤
JPS6112614A (ja) * 1984-06-27 1986-01-21 Lion Corp 水性パップ剤
JPS6388125A (ja) * 1987-08-29 1988-04-19 Rakuule Yakuhin Hanbai Kk インドメタシン配合のパップ剤
JPS63179820A (ja) * 1987-01-22 1988-07-23 Kao Corp 坐剤組成物
JPS63201119A (ja) * 1987-02-17 1988-08-19 Kao Corp 貼付剤組成物
JPH06501013A (ja) * 1990-09-28 1994-01-27 ザ、プロクター、エンド、ギャンブル、カンパニー 蒸気形でのエフェドリンベースのデリバリー用のエフェドリンベース及びサリチル酸アルキル含有組成物
JP2002154952A (ja) * 2000-11-15 2002-05-28 Ikeda Mohandou:Kk l−メントール高含有含水膏剤及びパッチ剤

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5446818A (en) * 1977-09-21 1979-04-13 Lion Dentifrice Co Ltd Surgical antiiinflammatory and anodyne agent
JPS5446816A (en) 1977-09-21 1979-04-13 Kirie Kawasaki Extracting of vitamin c and extracting container
JPS5467022A (en) * 1977-11-07 1979-05-30 Toko Yakuhin Kogyo Kk Topical agent and production thereof
DE3048369C2 (de) * 1980-12-22 1983-01-05 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V., 8000 München Abrasiv wirkende Mittel und deren Verwendung
LU84607A1 (fr) * 1983-01-26 1984-10-24 Oreal Compositions alcooliques ou hydroalcooliques contenant des essences naturelles et du benzylidene camphre ou ses derives
US4933184A (en) * 1983-12-22 1990-06-12 American Home Products Corp. (Del) Menthol enhancement of transdermal drug delivery
US5124320A (en) * 1989-09-12 1992-06-23 Ivy Jeffery W An external analgesic lotion containing active ingredients of camphor and menthol and method of making such lotion
US5013726A (en) * 1989-09-12 1991-05-07 Ivy Jeffery W External analgesic lotion containing active ingredients of methyl salicylate and camphor and menthol and method of making such lotion
CA2028496A1 (en) * 1989-10-31 1991-05-01 Tohru Nakao Thiophene compounds and their pharmaceutical uses
US5013728A (en) * 1990-05-04 1991-05-07 Colgate - Palmolive Company Composition for treating osteoporosis and hormonal imbalance
DE4027980A1 (de) * 1990-09-04 1992-03-05 Merck Patent Gmbh Dialkoxybenzylidenkampfer-derivate
US5322689A (en) * 1992-03-10 1994-06-21 The Procter & Gamble Company Topical aromatic releasing compositions
US5376688A (en) * 1992-12-18 1994-12-27 R. P. Scherer Corporation Enhanced solubility pharmaceutical solutions
US6113921A (en) * 1993-03-23 2000-09-05 Pharmos Corp. Topical and transdermal delivery system utilizing submicron oil spheres
US5853768A (en) * 1995-03-01 1998-12-29 Altadonna; James Topical preparation and method for pain relief
US5961997A (en) * 1997-03-25 1999-10-05 Swinehart; James M. Antipruritic composition
EP0981330B1 (en) * 1997-05-14 2002-08-07 Galen (Chemicals) Limited Topical compositions
WO2000009121A1 (fr) * 1998-08-10 2000-02-24 Nippon Hypox Laboratories Inc. Analgesiques anti-inflammatoires
US7138394B2 (en) * 2002-09-27 2006-11-21 Alpharx Inc. Vehicle for topical delivery of anti-inflammatory compounds
US20060241175A1 (en) * 2002-09-27 2006-10-26 Joseph Schwarz Vehicle for topical delivery of anti-inflammatory compounds

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5562013A (en) * 1978-11-02 1980-05-10 Rakuule Yakuhin Hanbai Kk Aqueous poultice comprising transcutaneous absorbable anti-inflammatory agent
JPS58189115A (ja) * 1982-04-30 1983-11-04 Kowa Co 外用剤
JPS6112614A (ja) * 1984-06-27 1986-01-21 Lion Corp 水性パップ剤
JPS63179820A (ja) * 1987-01-22 1988-07-23 Kao Corp 坐剤組成物
JPS63201119A (ja) * 1987-02-17 1988-08-19 Kao Corp 貼付剤組成物
JPS6388125A (ja) * 1987-08-29 1988-04-19 Rakuule Yakuhin Hanbai Kk インドメタシン配合のパップ剤
JPH06501013A (ja) * 1990-09-28 1994-01-27 ザ、プロクター、エンド、ギャンブル、カンパニー 蒸気形でのエフェドリンベースのデリバリー用のエフェドリンベース及びサリチル酸アルキル含有組成物
JP2002154952A (ja) * 2000-11-15 2002-05-28 Ikeda Mohandou:Kk l−メントール高含有含水膏剤及びパッチ剤

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2008013449A (ja) * 2006-07-04 2008-01-24 Taisho Pharmaceut Co Ltd ユビデカレノン含有自己乳化組成物
JP2012523408A (ja) * 2009-04-08 2012-10-04 カディラ・ヘルスケア・リミテッド ジクロフェナクの安定な医薬組成物
WO2015151990A1 (ja) * 2014-03-30 2015-10-08 小林製薬株式会社 外用医薬組成物
JP2015189759A (ja) * 2014-03-30 2015-11-02 小林製薬株式会社 外用医薬組成物
JP2015189760A (ja) * 2014-03-30 2015-11-02 小林製薬株式会社 外用医薬組成物
JP2024056733A (ja) * 2018-08-01 2024-04-23 ノビラ・ファーマシューティカルズ・インコーポレイテッド 薬剤を含む共晶溶媒、並びにその製造および使用方法
JP2022500446A (ja) * 2018-09-17 2022-01-04 ソシエテ・デクスプロワタシオン・デ・プロデュイ・プール・レ・アンデュストリー・シミック・セピックSociete D’Exploitation De Produits Pour Les Industries Chimiques Seppic 少なくとも1つの抗炎症物質を含む局所使用のための医薬組成物
JP7589144B2 (ja) 2018-09-17 2024-11-25 ソシエテ・デクスプロワタシオン・デ・プロデュイ・プール・レ・アンデュストリー・シミック・セピック 少なくとも1つの抗炎症物質を含む局所使用のための医薬組成物

Also Published As

Publication number Publication date
US20050158348A1 (en) 2005-07-21
CN100534530C (zh) 2009-09-02
US7781429B2 (en) 2010-08-24
US20040063794A1 (en) 2004-04-01
US20060211688A1 (en) 2006-09-21
CN1500524A (zh) 2004-06-02
MXPA03008947A (es) 2005-04-19
US7138394B2 (en) 2006-11-21

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