JP2004115525A - 抗炎症性化合物の局所搬送用搬送剤 - Google Patents
抗炎症性化合物の局所搬送用搬送剤 Download PDFInfo
- Publication number
- JP2004115525A JP2004115525A JP2003338818A JP2003338818A JP2004115525A JP 2004115525 A JP2004115525 A JP 2004115525A JP 2003338818 A JP2003338818 A JP 2003338818A JP 2003338818 A JP2003338818 A JP 2003338818A JP 2004115525 A JP2004115525 A JP 2004115525A
- Authority
- JP
- Japan
- Prior art keywords
- menthol
- composition
- camphor
- carrier according
- emulsion
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
- A61K31/05—Phenols
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/12—Ketones
- A61K31/122—Ketones having the oxygen directly attached to a ring, e.g. quinones, vitamin K1, anthralin
- A61K31/125—Camphor; Nuclear substituted derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Organic Chemistry (AREA)
- Dermatology (AREA)
- Pain & Pain Management (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Rheumatology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US10/255,951 US7138394B2 (en) | 2002-09-27 | 2002-09-27 | Vehicle for topical delivery of anti-inflammatory compounds |
Publications (2)
Publication Number | Publication Date |
---|---|
JP2004115525A true JP2004115525A (ja) | 2004-04-15 |
JP2004115525A5 JP2004115525A5 (enrdf_load_stackoverflow) | 2007-02-01 |
Family
ID=32029201
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2003338818A Pending JP2004115525A (ja) | 2002-09-27 | 2003-09-29 | 抗炎症性化合物の局所搬送用搬送剤 |
Country Status (4)
Country | Link |
---|---|
US (3) | US7138394B2 (enrdf_load_stackoverflow) |
JP (1) | JP2004115525A (enrdf_load_stackoverflow) |
CN (1) | CN100534530C (enrdf_load_stackoverflow) |
MX (1) | MXPA03008947A (enrdf_load_stackoverflow) |
Cited By (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2008013449A (ja) * | 2006-07-04 | 2008-01-24 | Taisho Pharmaceut Co Ltd | ユビデカレノン含有自己乳化組成物 |
JP2012523408A (ja) * | 2009-04-08 | 2012-10-04 | カディラ・ヘルスケア・リミテッド | ジクロフェナクの安定な医薬組成物 |
WO2015151990A1 (ja) * | 2014-03-30 | 2015-10-08 | 小林製薬株式会社 | 外用医薬組成物 |
JP2015189759A (ja) * | 2014-03-30 | 2015-11-02 | 小林製薬株式会社 | 外用医薬組成物 |
JP2022500446A (ja) * | 2018-09-17 | 2022-01-04 | ソシエテ・デクスプロワタシオン・デ・プロデュイ・プール・レ・アンデュストリー・シミック・セピックSociete D’Exploitation De Produits Pour Les Industries Chimiques Seppic | 少なくとも1つの抗炎症物質を含む局所使用のための医薬組成物 |
JP2024056733A (ja) * | 2018-08-01 | 2024-04-23 | ノビラ・ファーマシューティカルズ・インコーポレイテッド | 薬剤を含む共晶溶媒、並びにその製造および使用方法 |
Families Citing this family (40)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20060241175A1 (en) * | 2002-09-27 | 2006-10-26 | Joseph Schwarz | Vehicle for topical delivery of anti-inflammatory compounds |
US7138394B2 (en) * | 2002-09-27 | 2006-11-21 | Alpharx Inc. | Vehicle for topical delivery of anti-inflammatory compounds |
EP1858556A1 (en) * | 2005-03-16 | 2007-11-28 | Alpharx Inc. | Vehicle for topical delivery of anti-inflammatory compounds |
US20060240051A1 (en) * | 2005-04-26 | 2006-10-26 | Singleton Andy H | Eutectic blends containing a water soluble vitamin derivative |
AU2006243032A1 (en) * | 2005-05-05 | 2006-11-09 | Reckitt Benckiser Llc | Topical compositions |
US20070042007A1 (en) * | 2005-08-19 | 2007-02-22 | Joseph Schwarz | Topical composition for delivery of salicylate esters |
US20070048360A1 (en) * | 2005-08-23 | 2007-03-01 | R Carrara Dario N | Pharmaceutical compositions with melting point depressant agents and method of making same |
GT200600405A (es) * | 2005-09-07 | 2007-04-16 | Formula de microemulsión | |
AU2006330526B2 (en) * | 2005-12-22 | 2012-09-27 | Oakwood Laboratories, Llc | Sublimable sustained release delivery system and method of making same |
DE102006042742A1 (de) * | 2006-09-12 | 2008-03-27 | Barnikol-Keuten, Doris, Dr. | Nano-Vehikel für den transkutanen Transport, diese enthaltende Zubereitungen und deren Anwendung |
RU2463038C2 (ru) | 2006-10-17 | 2012-10-10 | Нуво Рисерч Инк. | Диклофенаковый гель |
HU227970B1 (en) * | 2007-07-10 | 2012-07-30 | Egis Gyogyszergyar Nyrt | Pharmaceutical compositions containing silicones of high volatility |
US8618164B2 (en) | 2009-03-31 | 2013-12-31 | Nuvo Research Inc. | Treatment of pain with topical diclofenac compounds |
CN101524325B (zh) * | 2009-04-03 | 2010-12-29 | 龚志成 | 复方薄荷脑微乳及其鼻用制剂 |
CA2785643A1 (en) | 2009-12-23 | 2011-06-30 | Nuvo Research Inc. | Highly permeating terbinafine formulation |
DE102010013064A1 (de) | 2010-03-26 | 2011-12-15 | Gabriele Blume | Neuartiges Trägersystem für den Transport von Wirkstoffen in die Haut |
EP2457554A1 (de) * | 2010-11-24 | 2012-05-30 | Symrise AG | Menthol enthaltende Mischung |
US9545429B1 (en) | 2011-09-03 | 2017-01-17 | Biolyte Laboratories, Llc | Homeopathic formulations |
US11154535B2 (en) | 2012-07-31 | 2021-10-26 | Egis Pharmaceuticals Plc | Transdermal formulation containing COX inhibitors |
US10045965B2 (en) | 2012-07-31 | 2018-08-14 | Egis Pharmaceuticals Plc | Transdermal formulation containing COX inhibitors |
US10045935B2 (en) | 2012-07-31 | 2018-08-14 | Egis Pharmaceuticals Plc | Transdermal formulation containing COX inhibitors |
FR2994386B1 (fr) * | 2012-08-07 | 2016-06-24 | Thorel Jean-Noel | Inhibition de l'adhesion de micro-organismes pathogenes par un ester de saccharose et/ou de sorbitan dans le traitement cosmetique de l'atopie cutanee |
WO2014095257A1 (en) | 2012-12-20 | 2014-06-26 | Unilever N.V. | Eutectic mixtures in personal care compositions |
CN104884034B (zh) * | 2012-12-20 | 2017-06-06 | 荷兰联合利华有限公司 | 个人护理组合物中的低共熔混合物 |
KR102187731B1 (ko) * | 2013-02-01 | 2020-12-07 | 디드롭스 컴퍼니 | 액체 멘톨 조성물 |
US20160000803A1 (en) * | 2013-02-22 | 2016-01-07 | Eastgate Pharmaceuticals Inc. | Pharmaceutical composition for transmucosal administration of benzodiazepines |
CA2978517A1 (en) | 2014-03-04 | 2015-09-11 | Eastgate Pharmaceuticals Inc. | Pharmaceutical composition for transmucosal delivery and methods for treating diabetes in a subject in need thereof |
US9012402B1 (en) | 2014-06-11 | 2015-04-21 | James Blanchard | Gel for topical delivery of NSAIDs to provide relief of musculoskeletal pain and methods for its preparation |
US9623062B2 (en) * | 2014-06-27 | 2017-04-18 | Jeju National University Industryacademic Cooperation Foundation | Anti-ageing activity of camphor in fibroblast cell line |
US10828251B1 (en) | 2017-01-14 | 2020-11-10 | Biolyte Laboratories, Llc | Homeopathic formulations |
US10617634B1 (en) | 2017-03-10 | 2020-04-14 | Biolyte Laboratories, Llc | Topical homeopathic formulations for menstrual cramps |
US10821075B1 (en) | 2017-07-12 | 2020-11-03 | James Blanchard | Compositions for topical application of a medicaments onto a mammalian body surface |
BR102019014454A2 (pt) * | 2018-07-13 | 2020-02-04 | Upl Ltd | composição compreendendo mistura eutética de fungicida boscalide e estrobilurina |
AU2019363244B2 (en) | 2018-10-15 | 2024-10-03 | Cipla Limited | Pharmaceutical formulation |
WO2020188547A1 (en) * | 2019-03-21 | 2020-09-24 | Universidade Nova De Lisboa | Terpene based therapeutic deep eutectic system, method of obtaining and uses thereof |
WO2020223093A1 (en) * | 2019-04-30 | 2020-11-05 | Bayer Healthcare Llc | Topical analgesic gel compositions |
FR3099697B1 (fr) * | 2019-08-09 | 2022-07-08 | Soc Dexploitation De Produits Pour Les Industries Chimiques Seppic | Composition pharmaceutique à usage topique se présentant sous la forme d’une phase dispersée à base d’au moins un diol court dans une phase grasse continue et comprenant au moins une substance anti-inflammatoire. |
WO2022055927A1 (en) * | 2020-09-11 | 2022-03-17 | Ps Therapy Ltd. | Topical compositions and methods of use |
US20250099369A1 (en) | 2023-09-27 | 2025-03-27 | Andros Pharmaceuticals Co., Ltd. | Topical delivery compositions comprising non-steroidal anti-inflammatory drugs |
CN118084849B (zh) * | 2024-01-22 | 2024-07-19 | 南京默可思泰医药科技有限公司 | 一种含有麝香草酚及其衍生物的胶束制剂的制备方法和应用 |
Citations (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5562013A (en) * | 1978-11-02 | 1980-05-10 | Rakuule Yakuhin Hanbai Kk | Aqueous poultice comprising transcutaneous absorbable anti-inflammatory agent |
JPS58189115A (ja) * | 1982-04-30 | 1983-11-04 | Kowa Co | 外用剤 |
JPS6112614A (ja) * | 1984-06-27 | 1986-01-21 | Lion Corp | 水性パップ剤 |
JPS6388125A (ja) * | 1987-08-29 | 1988-04-19 | Rakuule Yakuhin Hanbai Kk | インドメタシン配合のパップ剤 |
JPS63179820A (ja) * | 1987-01-22 | 1988-07-23 | Kao Corp | 坐剤組成物 |
JPS63201119A (ja) * | 1987-02-17 | 1988-08-19 | Kao Corp | 貼付剤組成物 |
JPH06501013A (ja) * | 1990-09-28 | 1994-01-27 | ザ、プロクター、エンド、ギャンブル、カンパニー | 蒸気形でのエフェドリンベースのデリバリー用のエフェドリンベース及びサリチル酸アルキル含有組成物 |
JP2002154952A (ja) * | 2000-11-15 | 2002-05-28 | Ikeda Mohandou:Kk | l−メントール高含有含水膏剤及びパッチ剤 |
Family Cites Families (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5446818A (en) * | 1977-09-21 | 1979-04-13 | Lion Dentifrice Co Ltd | Surgical antiiinflammatory and anodyne agent |
JPS5446816A (en) | 1977-09-21 | 1979-04-13 | Kirie Kawasaki | Extracting of vitamin c and extracting container |
JPS5467022A (en) * | 1977-11-07 | 1979-05-30 | Toko Yakuhin Kogyo Kk | Topical agent and production thereof |
DE3048369C2 (de) * | 1980-12-22 | 1983-01-05 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V., 8000 München | Abrasiv wirkende Mittel und deren Verwendung |
LU84607A1 (fr) * | 1983-01-26 | 1984-10-24 | Oreal | Compositions alcooliques ou hydroalcooliques contenant des essences naturelles et du benzylidene camphre ou ses derives |
US4933184A (en) * | 1983-12-22 | 1990-06-12 | American Home Products Corp. (Del) | Menthol enhancement of transdermal drug delivery |
US5124320A (en) * | 1989-09-12 | 1992-06-23 | Ivy Jeffery W | An external analgesic lotion containing active ingredients of camphor and menthol and method of making such lotion |
US5013726A (en) * | 1989-09-12 | 1991-05-07 | Ivy Jeffery W | External analgesic lotion containing active ingredients of methyl salicylate and camphor and menthol and method of making such lotion |
CA2028496A1 (en) * | 1989-10-31 | 1991-05-01 | Tohru Nakao | Thiophene compounds and their pharmaceutical uses |
US5013728A (en) * | 1990-05-04 | 1991-05-07 | Colgate - Palmolive Company | Composition for treating osteoporosis and hormonal imbalance |
DE4027980A1 (de) * | 1990-09-04 | 1992-03-05 | Merck Patent Gmbh | Dialkoxybenzylidenkampfer-derivate |
US5322689A (en) * | 1992-03-10 | 1994-06-21 | The Procter & Gamble Company | Topical aromatic releasing compositions |
US5376688A (en) * | 1992-12-18 | 1994-12-27 | R. P. Scherer Corporation | Enhanced solubility pharmaceutical solutions |
US6113921A (en) * | 1993-03-23 | 2000-09-05 | Pharmos Corp. | Topical and transdermal delivery system utilizing submicron oil spheres |
US5853768A (en) * | 1995-03-01 | 1998-12-29 | Altadonna; James | Topical preparation and method for pain relief |
US5961997A (en) * | 1997-03-25 | 1999-10-05 | Swinehart; James M. | Antipruritic composition |
EP0981330B1 (en) * | 1997-05-14 | 2002-08-07 | Galen (Chemicals) Limited | Topical compositions |
WO2000009121A1 (fr) * | 1998-08-10 | 2000-02-24 | Nippon Hypox Laboratories Inc. | Analgesiques anti-inflammatoires |
US7138394B2 (en) * | 2002-09-27 | 2006-11-21 | Alpharx Inc. | Vehicle for topical delivery of anti-inflammatory compounds |
US20060241175A1 (en) * | 2002-09-27 | 2006-10-26 | Joseph Schwarz | Vehicle for topical delivery of anti-inflammatory compounds |
-
2002
- 2002-09-27 US US10/255,951 patent/US7138394B2/en not_active Expired - Fee Related
-
2003
- 2003-09-27 CN CNB031650058A patent/CN100534530C/zh not_active Expired - Fee Related
- 2003-09-29 JP JP2003338818A patent/JP2004115525A/ja active Pending
- 2003-09-29 MX MXPA03008947A patent/MXPA03008947A/es active IP Right Grant
-
2005
- 2005-03-16 US US11/080,812 patent/US20050158348A1/en not_active Abandoned
-
2006
- 2006-05-18 US US11/435,939 patent/US7781429B2/en not_active Expired - Fee Related
Patent Citations (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5562013A (en) * | 1978-11-02 | 1980-05-10 | Rakuule Yakuhin Hanbai Kk | Aqueous poultice comprising transcutaneous absorbable anti-inflammatory agent |
JPS58189115A (ja) * | 1982-04-30 | 1983-11-04 | Kowa Co | 外用剤 |
JPS6112614A (ja) * | 1984-06-27 | 1986-01-21 | Lion Corp | 水性パップ剤 |
JPS63179820A (ja) * | 1987-01-22 | 1988-07-23 | Kao Corp | 坐剤組成物 |
JPS63201119A (ja) * | 1987-02-17 | 1988-08-19 | Kao Corp | 貼付剤組成物 |
JPS6388125A (ja) * | 1987-08-29 | 1988-04-19 | Rakuule Yakuhin Hanbai Kk | インドメタシン配合のパップ剤 |
JPH06501013A (ja) * | 1990-09-28 | 1994-01-27 | ザ、プロクター、エンド、ギャンブル、カンパニー | 蒸気形でのエフェドリンベースのデリバリー用のエフェドリンベース及びサリチル酸アルキル含有組成物 |
JP2002154952A (ja) * | 2000-11-15 | 2002-05-28 | Ikeda Mohandou:Kk | l−メントール高含有含水膏剤及びパッチ剤 |
Cited By (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2008013449A (ja) * | 2006-07-04 | 2008-01-24 | Taisho Pharmaceut Co Ltd | ユビデカレノン含有自己乳化組成物 |
JP2012523408A (ja) * | 2009-04-08 | 2012-10-04 | カディラ・ヘルスケア・リミテッド | ジクロフェナクの安定な医薬組成物 |
WO2015151990A1 (ja) * | 2014-03-30 | 2015-10-08 | 小林製薬株式会社 | 外用医薬組成物 |
JP2015189759A (ja) * | 2014-03-30 | 2015-11-02 | 小林製薬株式会社 | 外用医薬組成物 |
JP2015189760A (ja) * | 2014-03-30 | 2015-11-02 | 小林製薬株式会社 | 外用医薬組成物 |
JP2024056733A (ja) * | 2018-08-01 | 2024-04-23 | ノビラ・ファーマシューティカルズ・インコーポレイテッド | 薬剤を含む共晶溶媒、並びにその製造および使用方法 |
JP2022500446A (ja) * | 2018-09-17 | 2022-01-04 | ソシエテ・デクスプロワタシオン・デ・プロデュイ・プール・レ・アンデュストリー・シミック・セピックSociete D’Exploitation De Produits Pour Les Industries Chimiques Seppic | 少なくとも1つの抗炎症物質を含む局所使用のための医薬組成物 |
JP7589144B2 (ja) | 2018-09-17 | 2024-11-25 | ソシエテ・デクスプロワタシオン・デ・プロデュイ・プール・レ・アンデュストリー・シミック・セピック | 少なくとも1つの抗炎症物質を含む局所使用のための医薬組成物 |
Also Published As
Publication number | Publication date |
---|---|
US20050158348A1 (en) | 2005-07-21 |
CN100534530C (zh) | 2009-09-02 |
US7781429B2 (en) | 2010-08-24 |
US20040063794A1 (en) | 2004-04-01 |
US20060211688A1 (en) | 2006-09-21 |
CN1500524A (zh) | 2004-06-02 |
MXPA03008947A (es) | 2005-04-19 |
US7138394B2 (en) | 2006-11-21 |
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