JP2003525946A5 - - Google Patents

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JP2003525946A5
JP2003525946A5 JP2001565375A JP2001565375A JP2003525946A5 JP 2003525946 A5 JP2003525946 A5 JP 2003525946A5 JP 2001565375 A JP2001565375 A JP 2001565375A JP 2001565375 A JP2001565375 A JP 2001565375A JP 2003525946 A5 JP2003525946 A5 JP 2003525946A5
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Japan
Prior art keywords
heparinase iii
tumor
modified
administered
effective amount
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JP2001565375A
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English (en)
Japanese (ja)
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JP2003525946A (ja
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Priority claimed from PCT/US2001/007464 external-priority patent/WO2001066772A2/en
Publication of JP2003525946A publication Critical patent/JP2003525946A/ja
Publication of JP2003525946A5 publication Critical patent/JP2003525946A5/ja
Pending legal-status Critical Current

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JP2001565375A 2000-03-08 2001-03-08 ヘパリナーゼｉｉｉおよびその使用 Pending JP2003525946A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US18784600P 2000-03-08 2000-03-08
US60/187,846 2000-03-08
PCT/US2001/007464 WO2001066772A2 (en) 2000-03-08 2001-03-08 Heparinase iii and uses thereof

Publications (2)

Publication Number Publication Date
JP2003525946A JP2003525946A (ja) 2003-09-02
JP2003525946A5 true JP2003525946A5 (https=) 2008-05-08

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ID=22690719

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Application Number Title Priority Date Filing Date
JP2001565375A Pending JP2003525946A (ja) 2000-03-08 2001-03-08 ヘパリナーゼｉｉｉおよびその使用

Country Status (7)

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US (8) US6869789B2 (https=)
EP (1) EP1266013B1 (https=)
JP (1) JP2003525946A (https=)
AU (2) AU4351201A (https=)
CA (1) CA2402160C (https=)
ES (1) ES2527853T3 (https=)
WO (1) WO2001066772A2 (https=)

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US9616114B1 (en) 2014-09-18 2017-04-11 David Gordon Bermudes Modified bacteria having improved pharmacokinetics and tumor colonization enhancing antitumor activity
US10676723B2 (en) 2015-05-11 2020-06-09 David Gordon Bermudes Chimeric protein toxins for expression by therapeutic bacteria
WO2017049272A1 (en) * 2015-09-17 2017-03-23 Research Foundation Of The City University Of New York Method for mitigating metastasis
US11129906B1 (en) 2016-12-07 2021-09-28 David Gordon Bermudes Chimeric protein toxins for expression by therapeutic bacteria
US11180535B1 (en) 2016-12-07 2021-11-23 David Gordon Bermudes Saccharide binding, tumor penetration, and cytotoxic antitumor chimeric peptides from therapeutic bacteria
CN114703168B (zh) * 2022-03-02 2023-08-18 刘颖 一种肝素酶iii
WO2026037175A1 (zh) 2024-08-16 2026-02-19 上海宝济药业股份有限公司 靶向靶细胞的复合物及其应用

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