JP2003523319A5 - - Google Patents
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- Publication number
- JP2003523319A5 JP2003523319A5 JP2001524955A JP2001524955A JP2003523319A5 JP 2003523319 A5 JP2003523319 A5 JP 2003523319A5 JP 2001524955 A JP2001524955 A JP 2001524955A JP 2001524955 A JP2001524955 A JP 2001524955A JP 2003523319 A5 JP2003523319 A5 JP 2003523319A5
- Authority
- JP
- Japan
- Prior art keywords
- composition according
- composition
- stenosis
- biological
- elastase
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000000203 mixture Substances 0.000 claims description 25
- 102000016387 Pancreatic elastase Human genes 0.000 claims description 9
- 108010067372 Pancreatic elastase Proteins 0.000 claims description 9
- 210000003462 vein Anatomy 0.000 claims description 3
- 210000001367 artery Anatomy 0.000 claims description 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 8
- 208000031481 Pathologic Constriction Diseases 0.000 claims 5
- 230000036262 stenosis Effects 0.000 claims 5
- 208000037804 stenosis Diseases 0.000 claims 5
- 201000010099 disease Diseases 0.000 claims 4
- 208000035475 disorder Diseases 0.000 claims 4
- 238000001631 haemodialysis Methods 0.000 claims 4
- 230000000322 hemodialysis Effects 0.000 claims 4
- 102000029816 Collagenase Human genes 0.000 claims 3
- 108060005980 Collagenase Proteins 0.000 claims 3
- 229960002424 collagenase Drugs 0.000 claims 3
- 102000035195 Peptidases Human genes 0.000 claims 2
- 108091005804 Peptidases Proteins 0.000 claims 2
- 239000004365 Protease Substances 0.000 claims 2
- 206010020718 hyperplasia Diseases 0.000 claims 2
- 206010051341 Bile duct stenosis Diseases 0.000 claims 1
- 102000008186 Collagen Human genes 0.000 claims 1
- 108010035532 Collagen Proteins 0.000 claims 1
- 206010011086 Coronary artery occlusion Diseases 0.000 claims 1
- 102000016942 Elastin Human genes 0.000 claims 1
- 108010014258 Elastin Proteins 0.000 claims 1
- 102000010834 Extracellular Matrix Proteins Human genes 0.000 claims 1
- 108010037362 Extracellular Matrix Proteins Proteins 0.000 claims 1
- 241000124008 Mammalia Species 0.000 claims 1
- 229940122618 Trypsin inhibitor Drugs 0.000 claims 1
- 101710162629 Trypsin inhibitor Proteins 0.000 claims 1
- 210000000013 bile duct Anatomy 0.000 claims 1
- 210000004204 blood vessel Anatomy 0.000 claims 1
- 210000000621 bronchi Anatomy 0.000 claims 1
- 229920001436 collagen Polymers 0.000 claims 1
- 229920002549 elastin Polymers 0.000 claims 1
- 210000002744 extracellular matrix Anatomy 0.000 claims 1
- 230000003902 lesion Effects 0.000 claims 1
- 210000000277 pancreatic duct Anatomy 0.000 claims 1
- 239000002753 trypsin inhibitor Substances 0.000 claims 1
- 210000000626 ureter Anatomy 0.000 claims 1
- 239000008194 pharmaceutical composition Substances 0.000 description 17
- 239000003814 drug Substances 0.000 description 4
- 238000000034 method Methods 0.000 description 2
- 230000001225 therapeutic effect Effects 0.000 description 2
- 229940079593 drug Drugs 0.000 description 1
- 238000011200 topical administration Methods 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US15593899P | 1999-09-24 | 1999-09-24 | |
| US60/155,938 | 1999-09-24 | ||
| PCT/US2000/026237 WO2001021574A1 (en) | 1999-09-24 | 2000-09-24 | Systems and methods for opening obstructed biological conduits |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012085454A Division JP5793461B2 (ja) | 1999-09-24 | 2012-04-04 | 閉塞した生物学的管を開通するためのシステムと方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2003523319A JP2003523319A (ja) | 2003-08-05 |
| JP2003523319A5 true JP2003523319A5 (enExample) | 2008-09-04 |
| JP5763286B2 JP5763286B2 (ja) | 2015-08-12 |
Family
ID=22557384
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2001524955A Expired - Fee Related JP5763286B2 (ja) | 1999-09-24 | 2000-09-24 | 閉塞した生物学的管を開通するためのシステムと方法 |
| JP2012085454A Expired - Fee Related JP5793461B2 (ja) | 1999-09-24 | 2012-04-04 | 閉塞した生物学的管を開通するためのシステムと方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012085454A Expired - Fee Related JP5793461B2 (ja) | 1999-09-24 | 2012-04-04 | 閉塞した生物学的管を開通するためのシステムと方法 |
Country Status (11)
| Country | Link |
|---|---|
| EP (4) | EP2332568A1 (enExample) |
| JP (2) | JP5763286B2 (enExample) |
| AT (2) | ATE361095T1 (enExample) |
| AU (1) | AU7612100A (enExample) |
| CA (1) | CA2385488C (enExample) |
| CY (3) | CY1106656T1 (enExample) |
| DE (1) | DE60034694T2 (enExample) |
| DK (3) | DK1923068T3 (enExample) |
| ES (3) | ES2364191T3 (enExample) |
| PT (3) | PT1220830E (enExample) |
| WO (1) | WO2001021574A1 (enExample) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7063838B1 (en) | 1999-09-24 | 2006-06-20 | Proteon Therapeutics Llc | Methods for treating an artery or vein in a human subject |
| WO2004073504A2 (en) | 2003-02-20 | 2004-09-02 | Proteon Therapeutics, Llc | Methods for the treatment and prevention of diseases of biological conduits |
| JP2008513517A (ja) * | 2004-09-22 | 2008-05-01 | プロテオン セラペウチクス インコーポレーテッド | 生物学的導管の疾患の治療方法及び予防方法 |
| US10071143B1 (en) | 2007-05-03 | 2018-09-11 | The Research Foundation For The State University Of New York | Methods for non-surgical treatment of carpal tunnel syndrome |
| US8501449B2 (en) * | 2007-12-04 | 2013-08-06 | Proteon Therapeutics, Inc. | Recombinant elastase proteins and methods of manufacturing and use thereof |
| EP4015627B1 (en) | 2012-01-12 | 2023-09-27 | Endo Global Ventures | Clostridium histolyticum enzyme |
| US9636385B2 (en) | 2012-10-24 | 2017-05-02 | The Research Foundation For The State University Of New York | Use of collagenase to treat glaucoma |
| KR20230003601A (ko) | 2017-03-01 | 2023-01-06 | 엔도 벤쳐즈 리미티드 | 셀룰라이트를 평가하고 치료하기 위한 장치 및 방법 |
| KR20240001279A (ko) | 2017-03-28 | 2024-01-03 | 엔도 벤쳐즈 리미티드 | 개선된 콜라게나제 생성 방법 |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5489261A (en) * | 1981-01-26 | 1996-02-06 | Trustees Of Boston University | Hydrogels capable of supporting cell growth |
| US4636195A (en) * | 1982-04-02 | 1987-01-13 | Harvey Wolinsky | Method and apparatus for removing arterial constriction |
| US4803294A (en) * | 1987-10-29 | 1989-02-07 | G. D. Searle & Co. | Process and intermediates for the preparation of halogenated protease inhibitors |
| JPH0286777A (ja) * | 1988-09-22 | 1990-03-27 | Sankyo Co Ltd | サル膵臓エラスターゼｉ |
| DK0456724T3 (da) * | 1989-01-27 | 1995-10-02 | Immunolytics Inc | Præparat og fremgangsmåde til behandling af benign prostatisk hypertrofi |
| US5116615A (en) * | 1989-01-27 | 1992-05-26 | Immunolytics, Inc. | Method for treating benign prostatic hypertrophy |
| US5328470A (en) * | 1989-03-31 | 1994-07-12 | The Regents Of The University Of Michigan | Treatment of diseases by site-specific instillation of cells or site-specific transformation of cells and kits therefor |
| NL8900943A (nl) * | 1989-04-14 | 1990-11-01 | Euro Biopharm Technology B V | Protease inhibitor. |
| US5318531A (en) * | 1991-06-11 | 1994-06-07 | Cordis Corporation | Infusion balloon catheter |
| US5811447A (en) | 1993-01-28 | 1998-09-22 | Neorx Corporation | Therapeutic inhibitor of vascular smooth muscle cells |
| US5981568A (en) | 1993-01-28 | 1999-11-09 | Neorx Corporation | Therapeutic inhibitor of vascular smooth muscle cells |
| US5422261A (en) * | 1993-04-16 | 1995-06-06 | Baxter International Inc. | Composition containing collagenase and chymopapain for hydrolyzing connective tissue to isolate cells |
| US5409926A (en) | 1993-07-19 | 1995-04-25 | Merck & Co., Inc. | AT-2 antagonist inhibition of vascular restenosis |
| WO1996018725A1 (en) * | 1994-12-13 | 1996-06-20 | Human Genome Sciences, Inc. | Human tissue inhibitor of metalloproteinase-4 |
| US6020181A (en) * | 1995-05-17 | 2000-02-01 | New York Blood, Inc. | Inhibition of thrombus formation by medical related apparatus comprising treating with fibrinolytic matrix metalloproteinase |
| US5830468A (en) * | 1995-05-17 | 1998-11-03 | The New York Blood Center, Inc. | Fibrin(ogen) degradation by fibrinolytic matrix metalloproteinase |
| US5834449A (en) * | 1996-06-13 | 1998-11-10 | The Research Foundation Of State University Of New York | Treatment of aortic and vascular aneurysms with tetracycline compounds |
| ZA98376B (en) * | 1997-01-23 | 1998-07-23 | Hoffmann La Roche | Sulfamide-metalloprotease inhibitors |
-
2000
- 2000-09-24 PT PT00965396T patent/PT1220830E/pt unknown
- 2000-09-24 EP EP20100183002 patent/EP2332568A1/en not_active Withdrawn
- 2000-09-24 JP JP2001524955A patent/JP5763286B2/ja not_active Expired - Fee Related
- 2000-09-24 PT PT07008805T patent/PT1923068E/pt unknown
- 2000-09-24 PT PT101805331T patent/PT2363142E/pt unknown
- 2000-09-24 DK DK07008805T patent/DK1923068T3/da active
- 2000-09-24 EP EP10180533.1A patent/EP2363142B8/en not_active Expired - Lifetime
- 2000-09-24 DE DE2000634694 patent/DE60034694T2/de not_active Expired - Lifetime
- 2000-09-24 DK DK10180533T patent/DK2363142T3/en active
- 2000-09-24 DK DK00965396T patent/DK1220830T3/da active
- 2000-09-24 CA CA2385488A patent/CA2385488C/en not_active Expired - Fee Related
- 2000-09-24 ES ES07008805T patent/ES2364191T3/es not_active Expired - Lifetime
- 2000-09-24 ES ES10180533.1T patent/ES2534938T3/es not_active Expired - Lifetime
- 2000-09-24 WO PCT/US2000/026237 patent/WO2001021574A1/en not_active Ceased
- 2000-09-24 AT AT00965396T patent/ATE361095T1/de active
- 2000-09-24 ES ES00965396T patent/ES2284528T3/es not_active Expired - Lifetime
- 2000-09-24 EP EP20000965396 patent/EP1220830B1/en not_active Expired - Lifetime
- 2000-09-24 AU AU76121/00A patent/AU7612100A/en not_active Abandoned
- 2000-09-24 AT AT07008805T patent/ATE511854T1/de active
- 2000-09-24 EP EP20070008805 patent/EP1923068B1/en not_active Expired - Lifetime
-
2007
- 2007-06-14 CY CY20071100790T patent/CY1106656T1/el unknown
-
2011
- 2011-09-08 CY CY20111100865T patent/CY1112329T1/el unknown
-
2012
- 2012-04-04 JP JP2012085454A patent/JP5793461B2/ja not_active Expired - Fee Related
-
2015
- 2015-05-29 CY CY20151100477T patent/CY1117932T1/el unknown
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