JP2003522121A - 多発性硬化症の処置のためのリルゾールの使用 - Google Patents

多発性硬化症の処置のためのリルゾールの使用

Info

Publication number
JP2003522121A
JP2003522121A JP2001501213A JP2001501213A JP2003522121A JP 2003522121 A JP2003522121 A JP 2003522121A JP 2001501213 A JP2001501213 A JP 2001501213A JP 2001501213 A JP2001501213 A JP 2001501213A JP 2003522121 A JP2003522121 A JP 2003522121A
Authority
JP
Japan
Prior art keywords
riluzole
pharmaceutical composition
treatment
effective amount
patient
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2001501213A
Other languages
English (en)
Japanese (ja)
Other versions
JP2003522121A5 (enExample
Inventor
クリス ポルマン，
Original Assignee
フェレニヒング フォール クリステレイク ウェテンスハッペリキク オンデルウェイス
バイオジェン インコーポレイテッド
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by フェレニヒング フォール クリステレイク ウェテンスハッペリキク オンデルウェイス, バイオジェン インコーポレイテッド filed Critical フェレニヒング フォール クリステレイク ウェテンスハッペリキク オンデルウェイス
Publication of JP2003522121A publication Critical patent/JP2003522121A/ja
Publication of JP2003522121A5 publication Critical patent/JP2003522121A5/ja
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/428—Thiazoles condensed with carbocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
JP2001501213A 1999-06-04 2000-06-02 多発性硬化症の処置のためのリルゾールの使用 Pending JP2003522121A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
EP99201788.9 1999-06-04
EP99201788 1999-06-04
US17432800P 2000-01-04 2000-01-04
US60/174,328 2000-01-04
PCT/IB2000/000933 WO2000074676A1 (en) 1999-06-04 2000-06-02 Use of riluzole for the treatment of multiple sclerosis

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2007146265A Division JP2007262082A (ja) 1999-06-04 2007-05-31 多発性硬化症の処置のためのリルゾールの使用

Publications (2)

Publication Number Publication Date
JP2003522121A true JP2003522121A (ja) 2003-07-22
JP2003522121A5 JP2003522121A5 (enExample) 2007-07-19

Family

ID=56290027

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2001501213A Pending JP2003522121A (ja) 1999-06-04 2000-06-02 多発性硬化症の処置のためのリルゾールの使用

Country Status (11)

Country Link
EP (2) EP1552831B1 (enExample)
JP (1) JP2003522121A (enExample)
AT (2) ATE419851T1 (enExample)
AU (1) AU777537B2 (enExample)
CA (1) CA2375874A1 (enExample)
DE (1) DE60017733T2 (enExample)
ES (1) ES2235896T3 (enExample)
NZ (1) NZ515685A (enExample)
PT (1) PT1187612E (enExample)
SI (1) SI1187612T1 (enExample)
WO (1) WO2000074676A1 (enExample)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2007262082A (ja) * 1999-06-04 2007-10-11 Vereniging Voor Christelijk Wetenschappelijk Onderwijs 多発性硬化症の処置のためのリルゾールの使用
JP2009541391A (ja) * 2006-06-30 2009-11-26 コンシリオ ナツィオナーレ デッレ リチェルケ リルゾールを含有するナノ構造脂質担体および前記粒子を含有する医薬製剤
JP2012520254A (ja) * 2009-03-13 2012-09-06 イタルファルマコ ソシエタ ペル アチオニ リルゾール水性懸濁液
JP2017535569A (ja) * 2014-11-26 2017-11-30 メディシノバ・インコーポレイテッドＭｅｄｉｃｉＮｏｖａ， Ｉｎｃ． イブジラスト及びリルゾールの併用及びその使用法
JP2017535612A (ja) * 2014-11-21 2017-11-30 バイオヘイブン・ファーマシューティカル・ホールディング・カンパニー・リミテッドＢｉｏｈａｖｅｎ Ｐｈａｒｍａｃｅｕｔｉｃａｌ Ｈｏｌｄｉｎｇ Ｃｏｍｐａｎｙ Ｌｔｄ． リルゾールの舌下投与

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1100504A2 (en) 1998-07-02 2001-05-23 Eisai Co., Ltd. Pharmaceutical compositions and their uses for treatment of demyelinating disorders
IL136687A0 (en) * 2000-06-12 2001-06-14 Mor Research Applic Ltd Pharmaceutical composition for the treatment of multiple sclerosis
EP1778286A4 (en) * 2004-03-03 2009-04-08 Teva Pharma COMBINATION THERAPY WITH ACETATE OF GLATIRAMER AND RILUZOLE
WO2010113225A1 (en) * 2009-03-30 2010-10-07 Yutoku Pharmaceutical Industries Co., Ltd. Riluzole-containing transdermal patch

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997015306A1 (en) * 1995-10-25 1997-05-01 Janssen Pharmaceutica N.V. Infusions of neuroprotectants and perfluorochemicals
WO1997017970A1 (fr) * 1995-11-15 1997-05-22 Yamanouchi Pharmaceutical Co., Ltd. Inhibiteurs de la neurotoxicite de l'acide kainique et derives de la pyridothiazine
WO1997037652A1 (en) * 1996-04-10 1997-10-16 Kozachuk Walter E Methods of providing neuroprotection
WO1998030227A1 (en) * 1997-01-10 1998-07-16 Yeda Research And Development Co., Ltd. Treatment of multiple sclerosis through ingestion or inhalation of copolymer-1
JPH1179995A (ja) * 1997-09-04 1999-03-23 Otsuka Pharmaceut Co Ltd 多発性硬化症治療剤
JP2007262082A (ja) * 1999-06-04 2007-10-11 Vereniging Voor Christelijk Wetenschappelijk Onderwijs 多発性硬化症の処置のためのリルゾールの使用

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2688138B1 (fr) * 1992-03-06 1995-05-05 Rhone Poulenc Rorer Sa Application de l'amino-2 trifluoromethoxy-6 benzothiazole pour obtenir un medicament destine au traitement de la sclerose laterale amyotrophique.

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997015306A1 (en) * 1995-10-25 1997-05-01 Janssen Pharmaceutica N.V. Infusions of neuroprotectants and perfluorochemicals
WO1997017970A1 (fr) * 1995-11-15 1997-05-22 Yamanouchi Pharmaceutical Co., Ltd. Inhibiteurs de la neurotoxicite de l'acide kainique et derives de la pyridothiazine
WO1997037652A1 (en) * 1996-04-10 1997-10-16 Kozachuk Walter E Methods of providing neuroprotection
JP2000508318A (ja) * 1996-04-10 2000-07-04 コザチュク、ウォルター、イー 神経細胞の保護方法
WO1998030227A1 (en) * 1997-01-10 1998-07-16 Yeda Research And Development Co., Ltd. Treatment of multiple sclerosis through ingestion or inhalation of copolymer-1
JP2001511121A (ja) * 1997-01-10 2001-08-07 エダ リサーチ アンド ディベロップメント カンパニー，リミティド コポリマー１の摂取又は吸入を通じての多発性硬化症の治療
JPH1179995A (ja) * 1997-09-04 1999-03-23 Otsuka Pharmaceut Co Ltd 多発性硬化症治療剤
JP2007262082A (ja) * 1999-06-04 2007-10-11 Vereniging Voor Christelijk Wetenschappelijk Onderwijs 多発性硬化症の処置のためのリルゾールの使用

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2007262082A (ja) * 1999-06-04 2007-10-11 Vereniging Voor Christelijk Wetenschappelijk Onderwijs 多発性硬化症の処置のためのリルゾールの使用
JP2009541391A (ja) * 2006-06-30 2009-11-26 コンシリオ ナツィオナーレ デッレ リチェルケ リルゾールを含有するナノ構造脂質担体および前記粒子を含有する医薬製剤
JP2012520254A (ja) * 2009-03-13 2012-09-06 イタルファルマコ ソシエタ ペル アチオニ リルゾール水性懸濁液
JP2017535612A (ja) * 2014-11-21 2017-11-30 バイオヘイブン・ファーマシューティカル・ホールディング・カンパニー・リミテッドＢｉｏｈａｖｅｎ Ｐｈａｒｍａｃｅｕｔｉｃａｌ Ｈｏｌｄｉｎｇ Ｃｏｍｐａｎｙ Ｌｔｄ． リルゾールの舌下投与
JP2017535569A (ja) * 2014-11-26 2017-11-30 メディシノバ・インコーポレイテッドＭｅｄｉｃｉＮｏｖａ， Ｉｎｃ． イブジラスト及びリルゾールの併用及びその使用法
US11278531B2 (en) 2014-11-26 2022-03-22 Medicinova, Inc. Combination of ibudilast and riluzole and methods of using same

Also Published As

Publication number Publication date
EP1552831B1 (en) 2009-01-07
PT1187612E (pt) 2005-05-31
ES2235896T3 (es) 2005-07-16
WO2000074676A1 (en) 2000-12-14
AU777537B2 (en) 2004-10-21
NZ515685A (en) 2002-12-20
DE60017733T2 (de) 2006-01-12
DE60017733D1 (de) 2005-03-03
SI1187612T1 (en) 2005-06-30
EP1552831A1 (en) 2005-07-13
ATE419851T1 (de) 2009-01-15
ATE287713T1 (de) 2005-02-15
EP1187612A1 (en) 2002-03-20
EP1187612B1 (en) 2005-01-26
AU5421900A (en) 2000-12-28
CA2375874A1 (en) 2000-12-14

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