SI1187612T1 - Use of riluzole for the treatment of multiple sclerosis - Google Patents
Use of riluzole for the treatment of multiple sclerosisInfo
- Publication number
- SI1187612T1 SI1187612T1 SI200030601T SI200030601T SI1187612T1 SI 1187612 T1 SI1187612 T1 SI 1187612T1 SI 200030601 T SI200030601 T SI 200030601T SI 200030601 T SI200030601 T SI 200030601T SI 1187612 T1 SI1187612 T1 SI 1187612T1
- Authority
- SI
- Slovenia
- Prior art keywords
- riluzole
- treatment
- multiple sclerosis
- benzothiazolamine
- trifluoromethoxy
- Prior art date
Links
- FTALBRSUTCGOEG-UHFFFAOYSA-N Riluzole Chemical compound C1=C(OC(F)(F)F)C=C2SC(N)=NC2=C1 FTALBRSUTCGOEG-UHFFFAOYSA-N 0.000 title abstract 3
- 201000006417 multiple sclerosis Diseases 0.000 title abstract 2
- 229960004181 riluzole Drugs 0.000 title abstract 2
- 239000000203 mixture Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/428—Thiazoles condensed with carbocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
Landscapes
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Neurosurgery (AREA)
- Engineering & Computer Science (AREA)
- Neurology (AREA)
- Epidemiology (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Plural Heterocyclic Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP99201788 | 1999-06-04 | ||
| US17432800P | 2000-01-04 | 2000-01-04 | |
| PCT/IB2000/000933 WO2000074676A1 (en) | 1999-06-04 | 2000-06-02 | Use of riluzole for the treatment of multiple sclerosis |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SI1187612T1 true SI1187612T1 (en) | 2005-06-30 |
Family
ID=56290027
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SI200030601T SI1187612T1 (en) | 1999-06-04 | 2000-06-02 | Use of riluzole for the treatment of multiple sclerosis |
Country Status (11)
| Country | Link |
|---|---|
| EP (2) | EP1552831B1 (enExample) |
| JP (1) | JP2003522121A (enExample) |
| AT (2) | ATE287713T1 (enExample) |
| AU (1) | AU777537B2 (enExample) |
| CA (1) | CA2375874A1 (enExample) |
| DE (1) | DE60017733T2 (enExample) |
| ES (1) | ES2235896T3 (enExample) |
| NZ (1) | NZ515685A (enExample) |
| PT (1) | PT1187612E (enExample) |
| SI (1) | SI1187612T1 (enExample) |
| WO (1) | WO2000074676A1 (enExample) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1100504A2 (en) | 1998-07-02 | 2001-05-23 | Eisai Co., Ltd. | Pharmaceutical compositions and their uses for treatment of demyelinating disorders |
| DE60041365D1 (de) * | 1999-06-04 | 2009-02-26 | Vereniging Voor Christelijk Wetenschappelijk Onderwijs | Verwendung von Riluzol zur Behandlung Multipler Sklerose |
| IL136687A0 (en) * | 2000-06-12 | 2001-06-14 | Mor Research Applic Ltd | Pharmaceutical composition for the treatment of multiple sclerosis |
| EP1778286A4 (en) * | 2004-03-03 | 2009-04-08 | Teva Pharma | COMBINATION THERAPY WITH ACETATE OF GLATIRAMER AND RILUZOLE |
| ITMI20061274A1 (it) * | 2006-06-30 | 2008-01-01 | Consiglio Nazionale Ricerche | Vettori nanoparticellari lipidici contenenti riluzolo e composizioni farmaceutiche che li contengono |
| EP2228054A1 (en) | 2009-03-13 | 2010-09-15 | ITALFARMACO S.p.A. | Riluzole aqueous suspensions |
| WO2010113225A1 (en) * | 2009-03-30 | 2010-10-07 | Yutoku Pharmaceutical Industries Co., Ltd. | Riluzole-containing transdermal patch |
| EA201791110A1 (ru) * | 2014-11-21 | 2017-11-30 | Биохэвен Фармасьютикэл Холдинг Компани Лтд. | Сублингвальное введение рилузола |
| BR112017010700A2 (pt) * | 2014-11-26 | 2018-05-08 | Medicinova Inc | combinação de ibudilaste e riluzol e métodos de uso da mesma |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2688138B1 (fr) * | 1992-03-06 | 1995-05-05 | Rhone Poulenc Rorer Sa | Application de l'amino-2 trifluoromethoxy-6 benzothiazole pour obtenir un medicament destine au traitement de la sclerose laterale amyotrophique. |
| AU7298196A (en) * | 1995-10-25 | 1997-05-15 | Janssen Pharmaceutica N.V. | Infusions of neuroprotectants and perfluorochemicals |
| CN1202109A (zh) * | 1995-11-15 | 1998-12-16 | 山之内制药株式会社 | 红藻氨酸神经细胞毒性抑制剂及吡啶并噻嗪衍生物 |
| US5728728A (en) * | 1996-04-10 | 1998-03-17 | Kozachuk; Walter E. | Methods of providing neuroprotection |
| IL119989A0 (en) * | 1997-01-10 | 1997-04-15 | Yeda Res & Dev | Pharmaceutical compositions for oral treatment of multiple sclerosis |
| JP4120713B2 (ja) * | 1997-09-04 | 2008-07-16 | 大塚製薬株式会社 | 多発性硬化症治療剤 |
| DE60041365D1 (de) * | 1999-06-04 | 2009-02-26 | Vereniging Voor Christelijk Wetenschappelijk Onderwijs | Verwendung von Riluzol zur Behandlung Multipler Sklerose |
-
2000
- 2000-06-02 WO PCT/IB2000/000933 patent/WO2000074676A1/en not_active Ceased
- 2000-06-02 NZ NZ515685A patent/NZ515685A/xx not_active IP Right Cessation
- 2000-06-02 AT AT00939007T patent/ATE287713T1/de active
- 2000-06-02 AT AT05001476T patent/ATE419851T1/de not_active IP Right Cessation
- 2000-06-02 SI SI200030601T patent/SI1187612T1/xx unknown
- 2000-06-02 EP EP05001476A patent/EP1552831B1/en not_active Expired - Lifetime
- 2000-06-02 EP EP00939007A patent/EP1187612B1/en not_active Expired - Lifetime
- 2000-06-02 AU AU54219/00A patent/AU777537B2/en not_active Ceased
- 2000-06-02 PT PT00939007T patent/PT1187612E/pt unknown
- 2000-06-02 CA CA002375874A patent/CA2375874A1/en not_active Abandoned
- 2000-06-02 JP JP2001501213A patent/JP2003522121A/ja active Pending
- 2000-06-02 ES ES00939007T patent/ES2235896T3/es not_active Expired - Lifetime
- 2000-06-02 DE DE60017733T patent/DE60017733T2/de not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| EP1552831A1 (en) | 2005-07-13 |
| ES2235896T3 (es) | 2005-07-16 |
| WO2000074676A1 (en) | 2000-12-14 |
| EP1187612A1 (en) | 2002-03-20 |
| ATE419851T1 (de) | 2009-01-15 |
| EP1552831B1 (en) | 2009-01-07 |
| ATE287713T1 (de) | 2005-02-15 |
| AU777537B2 (en) | 2004-10-21 |
| EP1187612B1 (en) | 2005-01-26 |
| AU5421900A (en) | 2000-12-28 |
| NZ515685A (en) | 2002-12-20 |
| PT1187612E (pt) | 2005-05-31 |
| CA2375874A1 (en) | 2000-12-14 |
| JP2003522121A (ja) | 2003-07-22 |
| DE60017733D1 (de) | 2005-03-03 |
| DE60017733T2 (de) | 2006-01-12 |
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