JP2003519667A5 - - Google Patents

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Publication number
JP2003519667A5
JP2003519667A5 JP2001551501A JP2001551501A JP2003519667A5 JP 2003519667 A5 JP2003519667 A5 JP 2003519667A5 JP 2001551501 A JP2001551501 A JP 2001551501A JP 2001551501 A JP2001551501 A JP 2001551501A JP 2003519667 A5 JP2003519667 A5 JP 2003519667A5
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JP
Japan
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xaa
ala
gly
ser
twenty
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Pending
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JP2001551501A
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English (en)
Japanese (ja)
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JP2003519667A (ja
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Priority claimed from PCT/US2001/000719 external-priority patent/WO2001051078A1/en
Publication of JP2003519667A publication Critical patent/JP2003519667A/ja
Publication of JP2003519667A5 publication Critical patent/JP2003519667A5/ja
Pending legal-status Critical Current

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JP2001551501A 2000-01-10 2001-01-09 トリグリセリドレベルの調節および脂質異常血症の治療のためのエキセンジンおよびそのアゴニストの使用 Pending JP2003519667A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US17536500P 2000-01-10 2000-01-10
US60/175,365 2000-01-10
PCT/US2001/000719 WO2001051078A1 (en) 2000-01-10 2001-01-09 Use of exendins and agonists thereof for modulation of triglyceride levels and treatment of dyslipidemia

Publications (2)

Publication Number Publication Date
JP2003519667A JP2003519667A (ja) 2003-06-24
JP2003519667A5 true JP2003519667A5 (https=) 2007-02-08

Family

ID=22639978

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2001551501A Pending JP2003519667A (ja) 2000-01-10 2001-01-09 トリグリセリドレベルの調節および脂質異常血症の治療のためのエキセンジンおよびそのアゴニストの使用

Country Status (11)

Country Link
US (1) US20030036504A1 (https=)
EP (1) EP1246638B2 (https=)
JP (1) JP2003519667A (https=)
AT (1) ATE275967T1 (https=)
AU (1) AU2006202247A1 (https=)
CA (1) CA2396157A1 (https=)
DE (1) DE60105547T3 (https=)
DK (1) DK1246638T4 (https=)
ES (1) ES2227115T5 (https=)
PT (1) PT1246638E (https=)
WO (1) WO2001051078A1 (https=)

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US8076288B2 (en) 2004-02-11 2011-12-13 Amylin Pharmaceuticals, Inc. Hybrid polypeptides having glucose lowering activity
DE102004043153B4 (de) * 2004-09-03 2013-11-21 Philipps-Universität Marburg Erfindung betreffend GLP-1 und Exendin
US8263545B2 (en) 2005-02-11 2012-09-11 Amylin Pharmaceuticals, Inc. GIP analog and hybrid polypeptides with selectable properties
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ES2736184T3 (es) 2005-08-19 2019-12-26 Amylin Pharmaceuticals Llc Exendina para el tratamiento de la diabetes y la reducción del peso corporal
US8497240B2 (en) 2006-08-17 2013-07-30 Amylin Pharmaceuticals, Llc DPP-IV resistant GIP hybrid polypeptides with selectable properties
TWI428346B (zh) 2006-12-13 2014-03-01 Imp Innovations Ltd 新穎化合物及其等對進食行為影響
RU2413528C2 (ru) 2007-01-18 2011-03-10 Открытое Акционерное Общество "Валента Фармацевтика" Лекарственный препарат для лечения сахарного диабета на основе экзенатида и даларгина, применение и способ лечения
KR100805208B1 (ko) * 2007-03-27 2008-02-21 주식회사 펩트론 엑센딘 함유 서방성 제제 조성물, 엑센딘 함유 서방성미립구 및 이의 제조 방법
KR20100069651A (ko) * 2007-09-11 2010-06-24 몬도바이오테크 래보래토리즈 아게 Hcmv 감염의 치료를 위한 치료제로서의 bubuc 및 임의의 eaa-mart1(26-35)의 용도
WO2009043440A2 (en) * 2007-09-11 2009-04-09 Mondobiotech Laboratories Ag Use of il-1 receptor peptide, alone or in combination with d-ala-gln-octadecyl ester, as a therapeutic agent
EP2303313B1 (en) 2008-05-21 2015-10-28 Amylin Pharmaceuticals, LLC Exendins to lower cholestrol and triglycerides
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WO2009158412A2 (en) 2008-06-25 2009-12-30 Endo Pharmaceuticals Solutions Inc. Sustained delivery of exenatide and other polypeptides
EP2216042A1 (en) 2009-02-09 2010-08-11 Ipsen Pharma S.A.S. GLP-1 analogues pharmaceutical compositions
EP2435061A4 (en) 2009-05-28 2013-03-27 Amylin Pharmaceuticals Inc DAMPING GLP-1 RECEPTOR AGONIST COMPOUNDS
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JP2014504588A (ja) 2010-12-22 2014-02-24 アミリン・ファーマシューティカルズ,リミテッド・ライアビリティ・カンパニー 膵島細胞移植のためのglp−1受容体アゴニスト
UA116217C2 (uk) 2012-10-09 2018-02-26 Санофі Пептидна сполука як подвійний агоніст рецепторів glp1-1 та глюкагону
HK1211232A1 (en) 2012-12-21 2016-05-20 Sanofi Exendin-4 derivatives as dual glp1/gip or trigonal glp1/gip/glucagon agonists
WO2015086728A1 (en) 2013-12-13 2015-06-18 Sanofi Exendin-4 peptide analogues as dual glp-1/gip receptor agonists
TW201609799A (zh) 2013-12-13 2016-03-16 賽諾菲公司 雙重glp-1/gip受體促效劑
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TW201625668A (zh) 2014-04-07 2016-07-16 賽諾菲公司 作為胜肽性雙重glp-1/昇糖素受體激動劑之艾塞那肽-4衍生物
TW201625669A (zh) 2014-04-07 2016-07-16 賽諾菲公司 衍生自艾塞那肽-4(Exendin-4)之肽類雙重GLP-1/升糖素受體促效劑
TW201625670A (zh) 2014-04-07 2016-07-16 賽諾菲公司 衍生自exendin-4之雙重glp-1/升糖素受體促效劑
US9932381B2 (en) 2014-06-18 2018-04-03 Sanofi Exendin-4 derivatives as selective glucagon receptor agonists
RU2573933C1 (ru) 2014-08-21 2016-01-27 Дафот Энтерпрайсис Лимитед Пептид для лечения сахарного диабета 2-го типа и его осложнений
AR105319A1 (es) 2015-06-05 2017-09-27 Sanofi Sa Profármacos que comprenden un conjugado agonista dual de glp-1 / glucagón conector ácido hialurónico
AR105284A1 (es) 2015-07-10 2017-09-20 Sanofi Sa Derivados de exendina-4 como agonistas peptídicos duales específicos de los receptores de glp-1 / glucagón
KR102844773B1 (ko) 2015-12-23 2025-08-13 암젠 인크 위 억제 펩티드 수용체 (gipr)에 대한 결합 단백질을 glp-1 효능제와 조합하여 사용하여 대사 장애를 치료하거나 개선시키는 방법
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US11285180B2 (en) 2016-12-06 2022-03-29 Inserm (Institut National De La Sante Et De La Recherche Medicale) Methods of enhancing the potency of incretin-based drugs in subjects in need thereof
CA3047862A1 (en) * 2016-12-22 2018-06-28 Sanofi Fgf21 compound / glp-1r agonist combinations with optimized activity ratio
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CN110831969B (zh) 2017-06-20 2024-06-21 安进公司 使用抑胃肽受体(gipr)结合蛋白与glp-1激动剂的组合治疗或改善代谢障碍的方法
MX2019015544A (es) 2017-06-21 2020-07-28 Amgen Inc Metodo para tratar o mejorar trastornos metabolicos con proteinas de fusion de agonistas del receptor de glp-1/proteinas de union antagonistas para el receptor peptidico inhibidor gastrico (gipr).
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EP0996459B1 (en) * 1997-01-07 2005-09-21 Amylin Pharmaceuticals, Inc. Use of exendins and agonists thereof for the reduction of food intake
EP1037623A1 (en) * 1997-12-12 2000-09-27 Warner-Lambert Company Antihyperlipidemic statin-lp(a) inhibitor combinations
SE9801992D0 (sv) * 1998-06-04 1998-06-04 Astra Ab New 3-aryl-2-hydroxypropionic acid derivative I
JP2002544127A (ja) * 1999-04-30 2002-12-24 アミリン・ファーマシューティカルズ,インコーポレイテッド 修飾されたエキセンジンおよびエキセンジン・アゴニスト

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