JP2003515611A5 - - Google Patents

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Publication number
JP2003515611A5
JP2003515611A5 JP2001542722A JP2001542722A JP2003515611A5 JP 2003515611 A5 JP2003515611 A5 JP 2003515611A5 JP 2001542722 A JP2001542722 A JP 2001542722A JP 2001542722 A JP2001542722 A JP 2001542722A JP 2003515611 A5 JP2003515611 A5 JP 2003515611A5
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JP
Japan
Prior art keywords
eplerenone
solvate
shows
ethyl ketone
methyl ethyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2001542722A
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English (en)
Japanese (ja)
Other versions
JP2003515611A (ja
JP4219105B2 (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2000/030178 external-priority patent/WO2001041535A2/en
Publication of JP2003515611A publication Critical patent/JP2003515611A/ja
Publication of JP2003515611A5 publication Critical patent/JP2003515611A5/ja
Application granted granted Critical
Publication of JP4219105B2 publication Critical patent/JP4219105B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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JP2001542722A 1999-12-08 2000-12-04 エプレレノン結晶形 Expired - Fee Related JP4219105B2 (ja)

Applications Claiming Priority (13)

Application Number Priority Date Filing Date Title
US16980799P 1999-12-08 1999-12-08
US16960899P 1999-12-08 1999-12-08
US16970799P 1999-12-08 1999-12-08
US16968399P 1999-12-08 1999-12-08
US16955699P 1999-12-08 1999-12-08
US16963999P 1999-12-08 1999-12-08
US60/169,639 1999-12-08
US60/169,556 1999-12-08
US60/169,608 1999-12-08
US60/169,707 1999-12-08
US60/169,683 1999-12-08
US60/169,807 1999-12-08
PCT/US2000/030178 WO2001041535A2 (en) 1999-12-08 2000-12-04 Eplerenone crystalline form

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2006238694A Division JP2007016043A (ja) 1999-12-08 2006-09-04 エプレレノン結晶形

Publications (3)

Publication Number Publication Date
JP2003515611A JP2003515611A (ja) 2003-05-07
JP2003515611A5 true JP2003515611A5 (https=) 2006-01-05
JP4219105B2 JP4219105B2 (ja) 2009-02-04

Family

ID=27558586

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2001542722A Expired - Fee Related JP4219105B2 (ja) 1999-12-08 2000-12-04 エプレレノン結晶形
JP2006238694A Pending JP2007016043A (ja) 1999-12-08 2006-09-04 エプレレノン結晶形

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2006238694A Pending JP2007016043A (ja) 1999-12-08 2006-09-04 エプレレノン結晶形

Country Status (18)

Country Link
US (1) US20090149431A1 (https=)
EP (1) EP1175434A2 (https=)
JP (2) JP4219105B2 (https=)
KR (1) KR100584104B1 (https=)
CN (1) CN100413881C (https=)
AR (1) AR074665A2 (https=)
AU (1) AU2041101A (https=)
BR (1) BR0008054A (https=)
CA (1) CA2362845A1 (https=)
CO (1) CO5280205A1 (https=)
EA (1) EA008449B1 (https=)
HU (1) HUP0201457A3 (https=)
IL (2) IL144757A0 (https=)
MY (1) MY143571A (https=)
NO (1) NO20013857L (https=)
NZ (1) NZ513962A (https=)
PE (1) PE20010918A1 (https=)
WO (1) WO2001041535A2 (https=)

Families Citing this family (10)

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ITMI20010821A1 (it) * 2001-04-17 2002-10-17 Gienne Pharma S P A Impiego di composti derivati dallo spirolattone per inibire l'azione pro-fibrigenetica delle cellule stellate epatiche e delle cellule musco
US7235655B2 (en) 2002-03-22 2007-06-26 Pharmacia & Upjohn Company Processes to prepare eplerenone
EP2977084B1 (en) 2010-05-10 2017-07-05 INSERM (Institut National de la Santé et de la Recherche Médicale) Methods and compositions for the treatment of fluid accumulation in and/ or under the retina
JP6180930B2 (ja) 2010-06-16 2017-08-16 アンスティチュ ナショナル ドゥ ラ サンテ エ ドゥ ラ ルシェルシュ メディカル 創傷治癒過程における再上皮化を刺激するための方法及び組成物
CN104844681B (zh) * 2014-02-13 2016-06-01 合肥久诺医药科技有限公司 一种l晶型依普利酮的精制方法
JP6835836B2 (ja) 2015-10-13 2021-02-24 アンスティチュ ナショナル ドゥ ラ サンテ エ ドゥ ラ ルシェルシュ メディカル 脈絡膜血管新生の処置のための方法及び医薬組成物
EP3490606B8 (en) 2016-07-26 2024-04-10 INSERM (Institut National de la Santé et de la Recherche Médicale) Antagonist of mineralocorticoid receptor for the treatment of osteoarthritis
CN108059648A (zh) * 2017-12-30 2018-05-22 合肥久诺医药科技有限公司 一种依普利酮溶剂合物及其制备方法
CN113173968A (zh) * 2021-03-19 2021-07-27 江苏康思尔医药科技有限公司 一种依普利酮的纯化方法
US20240366632A1 (en) 2021-08-31 2024-11-07 Institut National de la Santé et de la Recherche Médicale Methods for the treatment of ocular rosacea

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