JP2003512426A5 - - Google Patents

Info

Publication number

JP2003512426A5

JP2003512426A5 JP2001532759A JP2001532759A JP2003512426A5 JP 2003512426 A5 JP2003512426 A5 JP 2003512426A5 JP 2001532759 A JP2001532759 A JP 2001532759A JP 2001532759 A JP2001532759 A JP 2001532759A JP 2003512426 A5 JP2003512426 A5 JP 2003512426A5

Authority

JP

Japan

Prior art keywords

use according

compound

salt

alkyl

hydrogen

Prior art date

2000-10-27

Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

Pending

Links

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• 150000001875 compounds Chemical class 0.000 description 7
• 229910052739 hydrogen Inorganic materials 0.000 description 6
• 239000001257 hydrogen Substances 0.000 description 6
• 150000003839 salts Chemical class 0.000 description 6
• VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 description 5
• 150000002431 hydrogen Chemical class 0.000 description 5
• 125000000217 alkyl group Chemical group 0.000 description 3
• 125000003710 aryl alkyl group Chemical group 0.000 description 3
• 125000003118 aryl group Chemical group 0.000 description 3
• UOOXDDHYFFXMJJ-LLVKDONJSA-N n-[(1r)-2,3-dihydro-1h-inden-1-yl]acetamide Chemical compound C1=CC=C2[C@H](NC(=O)C)CCC2=C1 UOOXDDHYFFXMJJ-LLVKDONJSA-N 0.000 description 3
• XJEVHMGJSYVQBQ-UHFFFAOYSA-N 2,3-dihydro-1h-inden-1-amine Chemical class C1=CC=C2C(N)CCC2=C1 XJEVHMGJSYVQBQ-UHFFFAOYSA-N 0.000 description 2
• BKAZIFPIBFUJFU-UHFFFAOYSA-N 2-amino-n-(2,3-dihydro-1h-inden-1-yl)acetamide Chemical compound C1=CC=C2C(NC(=O)CN)CCC2=C1 BKAZIFPIBFUJFU-UHFFFAOYSA-N 0.000 description 2
• 208000020925 Bipolar disease Diseases 0.000 description 2
• -1 C 1 -C 4 alkyl Chemical class 0.000 description 2
• 206010026749 Mania Diseases 0.000 description 2
• AFVFQIVMOAPDHO-UHFFFAOYSA-N Methanesulfonic acid Chemical compound CS(O)(=O)=O AFVFQIVMOAPDHO-UHFFFAOYSA-N 0.000 description 2
• QAOWNCQODCNURD-UHFFFAOYSA-L Sulfate Chemical compound [O-]S([O-])(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-L 0.000 description 2
• CCIVGXIOQKPBKL-UHFFFAOYSA-M ethanesulfonate Chemical compound CCS([O-])(=O)=O CCIVGXIOQKPBKL-UHFFFAOYSA-M 0.000 description 2
• DBGKPDNKZZGWOM-JTQLQIEISA-N n-[(1s)-2,3-dihydro-1h-inden-1-yl]formamide Chemical compound C1=CC=C2[C@@H](NC=O)CCC2=C1 DBGKPDNKZZGWOM-JTQLQIEISA-N 0.000 description 2
• QCQCHGYLTSGIGX-GHXANHINSA-N 4-[[(3ar,5ar,5br,7ar,9s,11ar,11br,13as)-5a,5b,8,8,11a-pentamethyl-3a-[(5-methylpyridine-3-carbonyl)amino]-2-oxo-1-propan-2-yl-4,5,6,7,7a,9,10,11,11b,12,13,13a-dodecahydro-3h-cyclopenta[a]chrysen-9-yl]oxy]-2,2-dimethyl-4-oxobutanoic acid Chemical compound N([C@@]12CC[C@@]3(C)[C@]4(C)CC[C@H]5C(C)(C)[C@@H](OC(=O)CC(C)(C)C(O)=O)CC[C@]5(C)[C@H]4CC[C@@H]3C1=C(C(C2)=O)C(C)C)C(=O)C1=CN=CC(C)=C1 QCQCHGYLTSGIGX-GHXANHINSA-N 0.000 description 1
• UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 description 1
• 239000003814 drug Substances 0.000 description 1
• 229910052736 halogen Inorganic materials 0.000 description 1
• 150000002367 halogens Chemical class 0.000 description 1
• 125000002887 hydroxy group Chemical group [H]O* 0.000 description 1
• 125000003392 indanyl group Chemical group C1(CCC2=CC=CC=C12)* 0.000 description 1
• 238000004519 manufacturing process Methods 0.000 description 1
• 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 description 1
• 239000000203 mixture Substances 0.000 description 1