JP2003510020A5 - - Google Patents
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- Publication number
- JP2003510020A5 JP2003510020A5 JP2001512926A JP2001512926A JP2003510020A5 JP 2003510020 A5 JP2003510020 A5 JP 2003510020A5 JP 2001512926 A JP2001512926 A JP 2001512926A JP 2001512926 A JP2001512926 A JP 2001512926A JP 2003510020 A5 JP2003510020 A5 JP 2003510020A5
- Authority
- JP
- Japan
- Prior art keywords
- analyte
- polynucleotide
- amplification
- amplicon
- target
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 238000003199 nucleic acid amplification method Methods 0.000 description 41
- 239000012491 analyte Substances 0.000 description 38
- 230000003321 amplification Effects 0.000 description 35
- 239000002157 polynucleotide Substances 0.000 description 32
- 238000006243 chemical reaction Methods 0.000 description 29
- 238000000034 method Methods 0.000 description 29
- 108091033319 polynucleotide Proteins 0.000 description 29
- 102000040430 polynucleotide Human genes 0.000 description 29
- 108091093088 Amplicon Proteins 0.000 description 25
- 239000000523 sample Substances 0.000 description 12
- 230000001404 mediated effect Effects 0.000 description 7
- 238000013518 transcription Methods 0.000 description 7
- 230000035897 transcription Effects 0.000 description 7
- 239000012472 biological sample Substances 0.000 description 4
- 102100034343 Integrase Human genes 0.000 description 3
- 239000003153 chemical reaction reagent Substances 0.000 description 3
- 108010014303 DNA-directed DNA polymerase Proteins 0.000 description 2
- 102000016928 DNA-directed DNA polymerase Human genes 0.000 description 2
- 108010092799 RNA-directed DNA polymerase Proteins 0.000 description 2
- 239000007787 solid Substances 0.000 description 2
- 235000011178 triphosphate Nutrition 0.000 description 2
- 239000001226 triphosphate Substances 0.000 description 2
- UNXRWKVEANCORM-UHFFFAOYSA-N triphosphoric acid Chemical compound OP(O)(=O)OP(O)(=O)OP(O)(O)=O UNXRWKVEANCORM-UHFFFAOYSA-N 0.000 description 2
- FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 description 1
- 239000003155 DNA primer Substances 0.000 description 1
- 102000004163 DNA-directed RNA polymerases Human genes 0.000 description 1
- 108090000626 DNA-directed RNA polymerases Proteins 0.000 description 1
- 101710203526 Integrase Proteins 0.000 description 1
- 108091034117 Oligonucleotide Proteins 0.000 description 1
- 230000027455 binding Effects 0.000 description 1
- 238000001514 detection method Methods 0.000 description 1
- 231100000673 dose–response relationship Toxicity 0.000 description 1
- 230000003100 immobilizing effect Effects 0.000 description 1
- 102000039446 nucleic acids Human genes 0.000 description 1
- 108020004707 nucleic acids Proteins 0.000 description 1
- 150000007523 nucleic acids Chemical class 0.000 description 1
- 239000002773 nucleotide Substances 0.000 description 1
- 125000003729 nucleotide group Chemical group 0.000 description 1
- 238000003752 polymerase chain reaction Methods 0.000 description 1
- 239000013615 primer Substances 0.000 description 1
- 238000011002 quantification Methods 0.000 description 1
- 230000009870 specific binding Effects 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US14543299P | 1999-07-23 | 1999-07-23 | |
| US60/145,432 | 1999-07-23 | ||
| PCT/US2000/020034 WO2001007661A2 (en) | 1999-07-23 | 2000-07-21 | Polynucleotide amplification method |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2003510020A JP2003510020A (ja) | 2003-03-18 |
| JP2003510020A5 true JP2003510020A5 (enExample) | 2007-08-30 |
| JP4796252B2 JP4796252B2 (ja) | 2011-10-19 |
Family
ID=22513089
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2001512926A Expired - Lifetime JP4796252B2 (ja) | 1999-07-23 | 2000-07-21 | ポリヌクレオチド増幅方法 |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US6294338B1 (enExample) |
| EP (1) | EP1238100B1 (enExample) |
| JP (1) | JP4796252B2 (enExample) |
| AT (1) | ATE304061T1 (enExample) |
| AU (1) | AU781570B2 (enExample) |
| CA (1) | CA2378408C (enExample) |
| DE (1) | DE60022541T2 (enExample) |
| DK (1) | DK1238100T3 (enExample) |
| ES (1) | ES2248096T3 (enExample) |
| WO (1) | WO2001007661A2 (enExample) |
Families Citing this family (34)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP4824236B2 (ja) * | 1999-07-09 | 2011-11-30 | ジェン−プローブ・インコーポレーテッド | 核酸増幅によるｈｉｖ−１の検出 |
| US6783934B1 (en) | 2000-05-01 | 2004-08-31 | Cepheid, Inc. | Methods for quantitative analysis of nucleic acid amplification reaction |
| US6582920B2 (en) | 2000-09-01 | 2003-06-24 | Gen-Probe Incorporated | Amplification of HIV-1 RT sequences for detection of sequences associated with drug-resistance mutations |
| NZ530602A (en) * | 2001-06-28 | 2006-02-24 | Chiron Corp | Methods for detecting human parvovirus B19 in a biological sample comprising hybridising primers with a target sequence, the presence of which indicates the presence of the virus |
| US6852491B2 (en) * | 2001-09-04 | 2005-02-08 | Abbott Laboratories | Amplification and detection reagents for HIV-1 |
| US7439346B2 (en) | 2001-10-12 | 2008-10-21 | Perkinelmer Las Inc. | Nucleic acids arrays and methods of use therefor |
| WO2003091426A1 (en) | 2001-10-12 | 2003-11-06 | Spectral Genomics, Inc. | Compilations of nucleic acids and arrays and methods of using them |
| US20030175709A1 (en) * | 2001-12-20 | 2003-09-18 | Murphy George L. | Method and system for depleting rRNA populations |
| JP2005524409A (ja) * | 2002-05-08 | 2005-08-18 | ファルマシア・イタリア・エス・ピー・エー | キメラ逆転写酵素及びテロメラーゼ阻害剤を同定する方法 |
| EP2292801B1 (en) * | 2002-06-14 | 2018-08-08 | Gen-Probe Incorporated | Compositions and methods for detecting hepatitis b virus |
| ES2524048T3 (es) | 2003-03-31 | 2014-12-03 | F. Hoffmann-La Roche Ag | Composiciones y métodos para la detección de ciertos flavivirus, incluidos los miembros del serogrupo del virus de la encefalitis japonesa |
| EP2292792B1 (en) | 2003-05-19 | 2013-11-20 | Gen-Probe Incorporated | Compositions, methods and kits for determining the presence of Trichomonas Vaginalis in a test sample |
| WO2005044086A2 (en) * | 2003-10-30 | 2005-05-19 | Tufts-New England Medical Center | Prenatal diagnosis using cell-free fetal dna in amniotic fluid |
| EP1737573A2 (en) * | 2004-04-08 | 2007-01-03 | Biomatrica, Inc. | Integration of sample storage and sample management for life science |
| US20080176209A1 (en) * | 2004-04-08 | 2008-07-24 | Biomatrica, Inc. | Integration of sample storage and sample management for life science |
| US20060099567A1 (en) * | 2004-04-08 | 2006-05-11 | Biomatrica, Inc. | Integration of sample storage and sample management for life science |
| US7939251B2 (en) | 2004-05-06 | 2011-05-10 | Roche Molecular Systems, Inc. | SENP1 as a marker for cancer |
| DK2975139T3 (da) * | 2004-09-30 | 2019-12-09 | Gen Probe Inc | Assay til at detektere og kvantificere hiv-1 |
| FR2878254B1 (fr) * | 2004-11-22 | 2010-08-20 | Bio Rad Pasteur | Composition pour l'amplification d'acides nucleiques |
| ES2530057T3 (es) * | 2005-01-21 | 2015-02-26 | Gene Express, Inc. | Composiciones y procedimientos de uso de mezclas estandarizadas |
| KR100654342B1 (ko) * | 2005-02-07 | 2006-12-08 | 삼성전자주식회사 | 이미지 센서 |
| EP1941058A4 (en) * | 2005-10-27 | 2010-01-20 | Rosetta Inpharmatics Llc | NUCLEIC ACID REINFORCEMENT FROM NON-INCIDENTIAL PRIMERS |
| EP1957645B1 (en) | 2005-12-06 | 2010-11-17 | Ambion Inc. | Reverse transcription primers and methods of design |
| WO2009137369A1 (en) * | 2008-05-03 | 2009-11-12 | Tufts Medical Center, Inc. | Neonatal salivary genomics |
| CA2768391C (en) | 2009-07-21 | 2016-09-06 | Gen-Probe Incorporated | Methods and compositions for quantitative detection of nucleic acid sequences over an extended dynamic range |
| CA2896129C (en) | 2010-01-22 | 2015-12-29 | Gen-Probe Incorporated | Probes for detecting the presence of trichomonas vaginalis in a sample |
| WO2011103274A1 (en) | 2010-02-17 | 2011-08-25 | Gen-Probe Incorporated | Compositions and methods to detect atopobium vaginae nucleic acid |
| CA2806734A1 (en) | 2010-07-26 | 2012-02-09 | Biomatrica, Inc. | Compositions for stabilizing dna, rna and proteins in saliva and other biological samples during shipping and storage at ambient temperatures |
| CA2806670A1 (en) | 2010-07-26 | 2012-02-09 | Biomatrica, Inc. | Compositions for stabilizing dna, rna and proteins in blood and other biological samples during shipping and storage at ambient temperatures |
| AU2012249751B2 (en) | 2011-04-25 | 2016-11-03 | Gen-Probe Incorporated | Compositions and methods for detecting BV-associated bacterial nucleic acid |
| EP3255155B1 (en) | 2011-09-08 | 2019-04-24 | Gen-Probe Incorporated | Compositions and methods for detecting bv-associated bacterial nucleic acid |
| HK1217117A1 (zh) | 2012-12-20 | 2016-12-23 | 生物马特里卡公司 | 用於使pcr试剂稳定化的制剂和方法 |
| WO2015191632A1 (en) | 2014-06-10 | 2015-12-17 | Biomatrica, Inc. | Stabilization of thrombocytes at ambient temperatures |
| WO2017100212A1 (en) | 2015-12-08 | 2017-06-15 | Biomatrica, Inc. | Reduction of erythrocyte sedimentation rate |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4683195A (en) | 1986-01-30 | 1987-07-28 | Cetus Corporation | Process for amplifying, detecting, and/or-cloning nucleic acid sequences |
| US5283174A (en) | 1987-09-21 | 1994-02-01 | Gen-Probe, Incorporated | Homogenous protection assay |
| CA1323293C (en) | 1987-12-11 | 1993-10-19 | Keith C. Backman | Assay using template-dependent nucleic acid probe reorganization |
| US5130238A (en) | 1988-06-24 | 1992-07-14 | Cangene Corporation | Enhanced nucleic acid amplification process |
| EP0731175A3 (en) * | 1989-07-11 | 2004-05-26 | Gen-Probe Incorporated | Oligonucleotide probes for HIV nucleic acid |
| CA2020958C (en) | 1989-07-11 | 2005-01-11 | Daniel L. Kacian | Nucleic acid sequence amplification methods |
| US5219727A (en) | 1989-08-21 | 1993-06-15 | Hoffmann-Laroche Inc. | Quantitation of nucleic acids using the polymerase chain reaction |
| US5455166A (en) | 1991-01-31 | 1995-10-03 | Becton, Dickinson And Company | Strand displacement amplification |
| GB9116042D0 (en) | 1991-07-24 | 1991-09-11 | Royal Free Hosp School Med | Diagnostic method |
| DE69233285T2 (de) | 1991-08-02 | 2004-11-25 | bioMérieux B.V. | Quantifikation von Nukleinsäuren |
| CA2135073C (en) | 1992-05-06 | 2002-11-19 | Daniel L. Kacian | Nucleic acid sequence amplification method, composition and kit |
| WO1994003472A1 (en) | 1992-08-04 | 1994-02-17 | Gen-Probe Incorporated | Nucleic acid sequence amplification |
| US5457027A (en) | 1993-05-05 | 1995-10-10 | Becton, Dickinson And Company | Internal controls for isothermal nucleic acid amplification reactions |
| CA2143857C (en) * | 1993-07-09 | 2005-09-20 | Marinus G. J. Van Beuningen | Improved method for the quantification of nucleic acid |
| KR100189229B1 (ko) | 1993-07-23 | 1999-06-01 | 다니엘 엘. 캐시앙, 헨리 엘. 노르호프 | 핵산 증폭을 강화하는 방법 |
| US5710029A (en) | 1995-06-07 | 1998-01-20 | Gen-Probe Incorporated | Methods for determining pre-amplification levels of a nucleic acid target sequence from post-amplification levels of product |
| US5705365A (en) | 1995-06-07 | 1998-01-06 | Gen-Probe Incorporated | Kits for determining pre-amplification levels of a nucleic acid target sequence from post-amplification levels of product |
| CA2223241C (en) * | 1995-06-07 | 2009-11-17 | Gen-Probe Incorporated | Methods and kits for determining pre-amplification levels of a nucleic acid target sequence from post-amplification levels of product |
| US5962665A (en) * | 1997-06-16 | 1999-10-05 | Abbott Laboratories | Nucleic acid primers and probes for detecting HIV-1 and HIV-2 |
| US5952202A (en) * | 1998-03-26 | 1999-09-14 | The Perkin Elmer Corporation | Methods using exogenous, internal controls and analogue blocks during nucleic acid amplification |
-
2000
- 2000-07-21 JP JP2001512926A patent/JP4796252B2/ja not_active Expired - Lifetime
- 2000-07-21 DK DK00948890T patent/DK1238100T3/da active
- 2000-07-21 AU AU62322/00A patent/AU781570B2/en not_active Expired
- 2000-07-21 WO PCT/US2000/020034 patent/WO2001007661A2/en not_active Ceased
- 2000-07-21 CA CA2378408A patent/CA2378408C/en not_active Expired - Lifetime
- 2000-07-21 EP EP00948890A patent/EP1238100B1/en not_active Expired - Lifetime
- 2000-07-21 AT AT00948890T patent/ATE304061T1/de active
- 2000-07-21 US US09/620,958 patent/US6294338B1/en not_active Expired - Lifetime
- 2000-07-21 DE DE60022541T patent/DE60022541T2/de not_active Expired - Lifetime
- 2000-07-21 ES ES00948890T patent/ES2248096T3/es not_active Expired - Lifetime
-
2001
- 2001-08-30 US US09/943,286 patent/US6908735B2/en not_active Expired - Lifetime
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