JP2003507025A - 偶発的dna分枝移動の抑制による核酸の相違の検出 - Google Patents

偶発的dna分枝移動の抑制による核酸の相違の検出

Info

Publication number
JP2003507025A
JP2003507025A JP2001516946A JP2001516946A JP2003507025A JP 2003507025 A JP2003507025 A JP 2003507025A JP 2001516946 A JP2001516946 A JP 2001516946A JP 2001516946 A JP2001516946 A JP 2001516946A JP 2003507025 A JP2003507025 A JP 2003507025A
Authority
JP
Japan
Prior art keywords
primer
sequence
target
nucleic acid
label
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2001516946A
Other languages
English (en)
Japanese (ja)
Other versions
JP2003507025A5 (https=
Inventor
アーラ・リシャンスキ
マーク・テイラー
ヌーリス・クーン
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Dade Behring Inc
Original Assignee
Dade Behring Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dade Behring Inc filed Critical Dade Behring Inc
Publication of JP2003507025A publication Critical patent/JP2003507025A/ja
Publication of JP2003507025A5 publication Critical patent/JP2003507025A5/ja
Pending legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813Hybridisation assays
    • C12Q1/6839Triple helix formation or other higher order conformations in hybridisation assays
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844Nucleic acid amplification reactions
    • C12Q1/6858Allele-specific amplification

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • General Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
JP2001516946A 1999-08-17 2000-08-15 偶発的dna分枝移動の抑制による核酸の相違の検出 Pending JP2003507025A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US09/376,097 1999-08-17
US09/376,097 US6232104B1 (en) 1999-08-17 1999-08-17 Detection of differences in nucleic acids by inhibition of spontaneous DNA branch migration
PCT/US2000/022446 WO2001012859A2 (en) 1999-08-17 2000-08-15 Detection of differences in nucleic acids by inhibition of spontaneous dna branch migration

Publications (2)

Publication Number Publication Date
JP2003507025A true JP2003507025A (ja) 2003-02-25
JP2003507025A5 JP2003507025A5 (https=) 2007-10-04

Family

ID=23483699

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2001516946A Pending JP2003507025A (ja) 1999-08-17 2000-08-15 偶発的dna分枝移動の抑制による核酸の相違の検出

Country Status (6)

Country Link
US (1) US6232104B1 (https=)
EP (1) EP1210457B1 (https=)
JP (1) JP2003507025A (https=)
DE (1) DE60033825T2 (https=)
ES (1) ES2281354T3 (https=)
WO (1) WO2001012859A2 (https=)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2003532119A (ja) * 2000-05-04 2003-10-28 デイド・ベーリング・マルブルク・ゲゼルシヤフト・ミツト・ベシユレンクテル・ハフツング 複数のアナライトの検出において使用するための組成物
JP2022519641A (ja) * 2019-02-04 2022-03-24 アコヤ・バイオサイエンシズ・インコーポレイテッド 生物学的試料の選択的標識による分析物検出

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4982921B2 (ja) * 2001-03-05 2012-07-25 ルネサスエレクトロニクス株式会社 半導体装置及びその製造方法
US6878530B2 (en) * 2002-02-07 2005-04-12 Panomics, Inc. Methods for detecting polymorphisms in nucleic acids
GB0310270D0 (en) * 2003-05-03 2003-06-11 Univ Edinburgh Biomolecular devices
US7273762B2 (en) 2004-11-09 2007-09-25 Freescale Semiconductor, Inc. Microelectromechanical (MEM) device including a spring release bridge and method of making the same
GB0518867D0 (en) * 2005-09-15 2005-10-26 Secretary Trade Ind Brit Microscopy tip
US20140302486A1 (en) * 2011-09-02 2014-10-09 President And Fellows Of Harvard College Systems and methods for detecting biomarkers of interest
SG10201510189WA (en) 2011-10-19 2016-01-28 Nugen Technologies Inc Compositions And Methods For Directional Nucleic Acid Amplification And Sequencing
EP4372084A3 (en) 2012-01-26 2024-08-14 Tecan Genomics, Inc. Compositions and methods for targeted nucleic acid sequence enrichment and high efficiency library generation
EP4026912A1 (en) 2012-05-10 2022-07-13 The General Hospital Corporation Methods for determining a nucleotide sequence
WO2013191775A2 (en) 2012-06-18 2013-12-27 Nugen Technologies, Inc. Compositions and methods for negative selection of non-desired nucleic acid sequences
US20150011396A1 (en) 2012-07-09 2015-01-08 Benjamin G. Schroeder Methods for creating directional bisulfite-converted nucleic acid libraries for next generation sequencing
EP2738263A1 (en) * 2012-11-30 2014-06-04 Fundacion para la Investigacion del Hospital Clinico de la Comunidad Valenciana Methods for DNA rearrengements analysis
US9822408B2 (en) 2013-03-15 2017-11-21 Nugen Technologies, Inc. Sequential sequencing
CA2929596C (en) 2013-11-13 2022-07-05 Nugen Technologies, Inc. Compositions and methods for identification of a duplicate sequencing read
JP7016215B2 (ja) 2014-01-27 2022-02-04 ザ ジェネラル ホスピタル コーポレイション 配列決定のために核酸を調製する方法
WO2015131107A1 (en) 2014-02-28 2015-09-03 Nugen Technologies, Inc. Reduced representation bisulfite sequencing with diversity adaptors
EP3287528A1 (de) 2016-08-25 2018-02-28 AGCT GmbH Verfahren zur amplifikation von nukleinsäuren und kit zu dessen durchführung
WO2018053362A1 (en) 2016-09-15 2018-03-22 ArcherDX, Inc. Methods of nucleic acid sample preparation
CA3037190A1 (en) 2016-09-15 2018-03-22 ArcherDX, Inc. Methods of nucleic acid sample preparation for analysis of cell-free dna
US12492430B2 (en) 2017-04-11 2025-12-09 Tecan Genomics, Inc. Library quantitation and qualification
US11099202B2 (en) 2017-10-20 2021-08-24 Tecan Genomics, Inc. Reagent delivery system
EP3851542A1 (en) 2020-01-20 2021-07-21 Tecan Genomics, Inc. Depletion of abundant uninformative sequences
US12059674B2 (en) 2020-02-03 2024-08-13 Tecan Genomics, Inc. Reagent storage system

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997023646A1 (en) * 1995-12-22 1997-07-03 Behringwerke Aktiengesellschaft Detection of differences in nucleic acids

Family Cites Families (42)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1254114A (en) 1984-05-07 1989-05-16 Allied Corporation Displacement polynucleotide assay employing recombination protein and diagnostic kit
US4683202A (en) 1985-03-28 1987-07-28 Cetus Corporation Process for amplifying nucleic acid sequences
JP2650159B2 (ja) 1988-02-24 1997-09-03 アクゾ・ノベル・エヌ・ベー 核酸増幅方法
US5622820A (en) 1988-03-10 1997-04-22 City Of Hope Method for amplification and detection of RNA and DNA sequences
WO1990002819A1 (en) 1988-09-08 1990-03-22 The Salk Institute For Biological Studies Replicative rna-based amplification detection systems
US5508178A (en) 1989-01-19 1996-04-16 Rose; Samuel Nucleic acid amplification using single primer
US5556750A (en) 1989-05-12 1996-09-17 Duke University Methods and kits for fractionating a population of DNA molecules based on the presence or absence of a base-pair mismatch utilizing mismatch repair systems
US5035996A (en) 1989-06-01 1991-07-30 Life Technologies, Inc. Process for controlling contamination of nucleic acid amplification reactions
US5766849A (en) 1989-07-11 1998-06-16 Gen-Probe Incorporated Methods of amplifying nucleic acids using promoter-containing primer sequence
GB8920097D0 (en) 1989-09-06 1989-10-18 Ici Plc Amplification processes
US5187066A (en) 1990-02-14 1993-02-16 Syntex (U.S.A.) Inc. Methods for detecting amphiphilic antigens
CA2037349C (en) 1990-03-26 2008-06-17 James G. Wetmur Branch migration of nucleotides
HU218095B (hu) 1990-05-01 2000-05-28 Amgen Inc. Eljárás átvitt szennyeződések csökkentésére, amplifikációs eljárásokban
US5595891A (en) 1990-07-19 1997-01-21 Behringwerke Ag Method for producing a polynucleotide for use in single primer amplification
US5525462A (en) 1991-05-02 1996-06-11 Toyo Boseki Kabushiki Kaisha Nucleic acid sequence amplification method, detection method, and reagent kit therefor
ES2091976T3 (es) * 1991-06-20 1996-11-16 Hoffmann La Roche Metodos perfeccionados para la amplificacion del acido nucleico.
US5582981A (en) 1991-08-14 1996-12-10 Gilead Sciences, Inc. Method for identifying an oligonucleotide aptamer specific for a target
EP0543484B1 (en) 1991-08-30 2001-01-31 Research Development Corporation of Japan A method of DNA amplification
DE4213029A1 (de) 1991-09-26 1993-04-01 Boehringer Mannheim Gmbh Verfahren zur spezifischen vervielfaeltigung von nukleins aeuresequenzen
ATE193558T1 (de) 1991-11-15 2000-06-15 Igen Int Inc Schnelle bestimmungsverfahren für amplifikationsprodukte
US5567583A (en) 1991-12-16 1996-10-22 Biotronics Corporation Methods for reducing non-specific priming in DNA detection
WO1993017127A1 (en) 1992-02-20 1993-09-02 The State Of Oregon Acting By And Through The Oregon State Board Of Higher Education On Behalf Of Oregon State University Boomerand dna amplification
FR2690691B1 (fr) 1992-04-29 1999-02-12 Bio Merieux Procede d'amplification d'arn necessitant une seule etape de manipulation.
JP4137996B2 (ja) 1992-05-06 2008-08-20 ジェン−プローブ・インコーポレイテッド 核酸配列増幅方法,組成物及びキット
ATE162892T1 (de) 1992-07-31 1998-02-15 Behringwerke Ag Photoaktivierbare chemiluminizierende matrices
US5340728A (en) 1992-12-09 1994-08-23 E. I. Du Pont De Nemours And Company Method for amplification of targeted segments of nucleic acid using nested polymerase chain reaction
US5593840A (en) 1993-01-27 1997-01-14 Oncor, Inc. Amplification of nucleic acid sequences
US5616464A (en) 1994-12-27 1997-04-01 Naxcor Nucleic acid sequence detection employing amplification probes
US5470723A (en) 1993-05-05 1995-11-28 Becton, Dickinson And Company Detection of mycobacteria by multiplex nucleic acid amplification
US5422252A (en) * 1993-06-04 1995-06-06 Becton, Dickinson And Company Simultaneous amplification of multiple targets
WO1995003430A1 (en) * 1993-07-23 1995-02-02 Gen-Probe Incorporated Methods for enhancing nucleic acid amplification
AU7551594A (en) 1993-07-29 1995-02-28 MURASHIGE, Kate H. Method for recognition of the nucleotide sequence of a purified dna segment
US5556773A (en) 1993-08-06 1996-09-17 Yourno; Joseph Method and apparatus for nested polymerase chain reaction (PCR) with single closed reaction tubes
US5480783A (en) 1994-03-31 1996-01-02 The Perkin-Elmer Corporation Method for reducing background signals in DNA replication/detection assays
US5580730A (en) 1994-08-19 1996-12-03 Olympus America, Inc. Enzyme digestion method for the detection of amplified DNA
FR2724934B1 (fr) 1994-09-26 1997-01-24 Bio Merieux Oligonucleotide chimere et son utilisation dans l'obtention de transcrits d'un acide nucleique
US5512441A (en) 1994-11-15 1996-04-30 American Health Foundation Quantative method for early detection of mutant alleles and diagnostic kits for carrying out the method
US5710029A (en) 1995-06-07 1998-01-20 Gen-Probe Incorporated Methods for determining pre-amplification levels of a nucleic acid target sequence from post-amplification levels of product
FR2737223B1 (fr) * 1995-07-24 1997-09-12 Bio Merieux Procede d'amplification de sequences d'acide nucleique par deplacement, a l'aide d'amorces chimeres
US5681705A (en) 1995-08-28 1997-10-28 Schram; James L. Amplification and detection of mycobacterium avium complex species
US5780231A (en) 1995-11-17 1998-07-14 Lynx Therapeutics, Inc. DNA extension and analysis with rolling primers
WO2000043546A2 (en) * 1999-01-19 2000-07-27 Dade Behring Inc. Detection of drug resistant organisms

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997023646A1 (en) * 1995-12-22 1997-07-03 Behringwerke Aktiengesellschaft Detection of differences in nucleic acids

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
JPN6010046489, J. Mol. Biol., 1998, Vol.279, p.795−806 *
JPN6010046490, J. Mol. Biol., 1993, Vol.230, p.413−424 *

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2003532119A (ja) * 2000-05-04 2003-10-28 デイド・ベーリング・マルブルク・ゲゼルシヤフト・ミツト・ベシユレンクテル・ハフツング 複数のアナライトの検出において使用するための組成物
JP4796259B2 (ja) * 2000-05-04 2011-10-19 シーメンス・ヘルスケア・ダイアグノスティックス・プロダクツ・ゲーエムベーハー 複数のアナライトの検出において使用するための組成物
JP2022519641A (ja) * 2019-02-04 2022-03-24 アコヤ・バイオサイエンシズ・インコーポレイテッド 生物学的試料の選択的標識による分析物検出
JP7549587B2 (ja) 2019-02-04 2024-09-11 アコヤ・バイオサイエンシズ・インコーポレイテッド 生物学的試料の選択的標識による分析物検出
JP2024163169A (ja) * 2019-02-04 2024-11-21 アコヤ・バイオサイエンシズ・インコーポレイテッド 生物学的試料の選択的標識による分析物検出

Also Published As

Publication number Publication date
WO2001012859A2 (en) 2001-02-22
EP1210457B1 (en) 2007-03-07
DE60033825T2 (de) 2007-11-08
WO2001012859A3 (en) 2002-01-31
EP1210457A2 (en) 2002-06-05
US6232104B1 (en) 2001-05-15
DE60033825D1 (de) 2007-04-19
ES2281354T3 (es) 2007-10-01

Similar Documents

Publication Publication Date Title
JP2003507025A (ja) 偶発的dna分枝移動の抑制による核酸の相違の検出
US6555317B2 (en) Detection of differences in nucleic acids
US6482590B1 (en) Method for polynucleotide amplification
KR0173133B1 (ko) 생체외 증폭을 이용한 폴리뉴클레오티드 검체분석
US6200757B1 (en) Method for controlling the extension of an oligonucleotide
JP2001517925A (ja) 核酸の均質増幅および検出
CN110088297A (zh) 锁式探针检测方法
WO2000070095A2 (en) Homogeneous isothermal amplification and detection of nucleic acids using a template switch oligonucleotide
CN103946397A (zh) 用于通用实时多重分析检测的双功能寡核苷酸探针
JPS60244300A (ja) 組換えタンパク質を用いる置換ポリヌクレオチド検定および診断用キツド
JP2009261406A (ja) β2アドレナリン多型検出
US20030152924A1 (en) Strand displacement detection of target nucleic acid
JPH02238900A (ja) 架橋補体を用いるヌクレオチドプローブの製造方法
US5605796A (en) Method for preventing amplification of nucleic acid contaminants in amplification mixtures using nuclease-receptor conjugates
WO2001090399A2 (en) Detection of mutations and polymorphisms in nucleic acids
JPH0714359B2 (ja) 修飾核酸の製造方法
WO1999042616A1 (en) Methods for determining concentrations of nucleic acids
WO2000043543A1 (en) Detection of differences between polynucleotides
WO2000043545A2 (en) Detection of drug resistant organisms
Nelson Rapid detection of genetic mutations using the chemiluminescent hybridization protection assay (HPA): overview and comparison with other methods
WO2000043546A9 (en) Detection of drug resistant organisms
JPS60179657A (ja) 標識プロ−ブ及び抗−ハイブリツドを用いるハイブリツド形成分析法
WO1999042615A1 (en) Methods for determining amounts of nucleic acids
WO2006051991A1 (ja) 核酸の増幅および検出方法
JPWO1996023077A1 (ja) 遺伝子増幅用プライマー、該プライマーを用いた核酸の識別方法及び核酸の識別用検査セット

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20070807

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20070807

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20100817

A02 Decision of refusal

Free format text: JAPANESE INTERMEDIATE CODE: A02

Effective date: 20110201