JP2003505345A5 - - Google Patents
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- Publication number
- JP2003505345A5 JP2003505345A5 JP2001502855A JP2001502855A JP2003505345A5 JP 2003505345 A5 JP2003505345 A5 JP 2003505345A5 JP 2001502855 A JP2001502855 A JP 2001502855A JP 2001502855 A JP2001502855 A JP 2001502855A JP 2003505345 A5 JP2003505345 A5 JP 2003505345A5
- Authority
- JP
- Japan
- Prior art keywords
- parenteral
- drug
- skin surface
- transdermal
- composition
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000000203 mixture Substances 0.000 description 5
- 239000003814 drug Substances 0.000 description 4
- 229940079593 drug Drugs 0.000 description 4
- 238000009472 formulation Methods 0.000 description 2
- 239000007943 implant Substances 0.000 description 2
- 239000012049 topical pharmaceutical composition Substances 0.000 description 2
- 239000006071 cream Substances 0.000 description 1
- 239000000499 gel Substances 0.000 description 1
- 238000002513 implantation Methods 0.000 description 1
- 238000001361 intraarterial administration Methods 0.000 description 1
- 238000007918 intramuscular administration Methods 0.000 description 1
- 238000001990 intravenous administration Methods 0.000 description 1
- 239000002674 ointment Substances 0.000 description 1
- 239000006072 paste Substances 0.000 description 1
- 239000007921 spray Substances 0.000 description 1
- 230000000699 topical effect Effects 0.000 description 1
- -1 transdermal patches Substances 0.000 description 1
- 239000006213 vaginal ring Substances 0.000 description 1
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US13885499P | 1999-06-11 | 1999-06-11 | |
| US13885199P | 1999-06-11 | 1999-06-11 | |
| US13932399P | 1999-06-11 | 1999-06-11 | |
| US60/139,323 | 1999-06-11 | ||
| US60/138,851 | 1999-06-11 | ||
| US60/138,854 | 1999-06-11 | ||
| PCT/US2000/015834 WO2000076522A1 (en) | 1999-06-11 | 2000-06-09 | Administration of non-oral androgenic steroids to women |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012225943A Division JP2013049682A (ja) | 1999-06-11 | 2012-10-11 | 女性への非経口アンドロゲンステロイドの投与 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2003505345A JP2003505345A (ja) | 2003-02-12 |
| JP2003505345A5 true JP2003505345A5 (enExample) | 2011-04-21 |
| JP5184727B2 JP5184727B2 (ja) | 2013-04-17 |
Family
ID=27385240
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2001502855A Expired - Lifetime JP5184727B2 (ja) | 1999-06-11 | 2000-06-09 | 女性への非経口アンドロゲンステロイドの投与 |
| JP2012225943A Pending JP2013049682A (ja) | 1999-06-11 | 2012-10-11 | 女性への非経口アンドロゲンステロイドの投与 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012225943A Pending JP2013049682A (ja) | 1999-06-11 | 2012-10-11 | 女性への非経口アンドロゲンステロイドの投与 |
Country Status (25)
| Country | Link |
|---|---|
| US (3) | US6583129B1 (enExample) |
| EP (1) | EP1189619A4 (enExample) |
| JP (2) | JP5184727B2 (enExample) |
| KR (2) | KR20020011437A (enExample) |
| CN (1) | CN1220491C (enExample) |
| AR (1) | AR024566A1 (enExample) |
| AU (1) | AU775145B2 (enExample) |
| BR (1) | BR0011740A (enExample) |
| CA (1) | CA2376797C (enExample) |
| CO (1) | CO5180583A1 (enExample) |
| CZ (1) | CZ299198B6 (enExample) |
| HK (1) | HK1048269B (enExample) |
| HU (1) | HUP0301813A2 (enExample) |
| IL (1) | IL147010A0 (enExample) |
| MX (1) | MXPA01012769A (enExample) |
| MY (1) | MY126960A (enExample) |
| NO (1) | NO20016046L (enExample) |
| NZ (1) | NZ516502A (enExample) |
| PE (1) | PE20010404A1 (enExample) |
| PL (1) | PL352250A1 (enExample) |
| SA (1) | SA00210404B1 (enExample) |
| SK (1) | SK18212001A3 (enExample) |
| TR (1) | TR200200406T2 (enExample) |
| TW (1) | TWI281398B (enExample) |
| WO (1) | WO2000076522A1 (enExample) |
Families Citing this family (76)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1997012623A1 (en) * | 1995-10-06 | 1997-04-10 | Arch Development Corporation | Methods and compositions for viral enhancement of cell killing |
| IL120266A (en) | 1996-02-28 | 2005-05-17 | Pfizer | Use of estrogen antagonists and estrogen agonists in the preparation of medicaments for inhibiting pathological conditions |
| US7153845B2 (en) | 1998-08-25 | 2006-12-26 | Columbia Laboratories, Inc. | Bioadhesive progressive hydration tablets |
| US6624200B2 (en) | 1998-08-25 | 2003-09-23 | Columbia Laboratories, Inc. | Bioadhesive progressive hydration tablets |
| CO5180583A1 (es) * | 1999-06-11 | 2002-07-30 | Watson Pharmaceuticals Inc | Administracion de esteroides androgenicos no orales a las mujeres |
| US6503894B1 (en) | 2000-08-30 | 2003-01-07 | Unimed Pharmaceuticals, Inc. | Pharmaceutical composition and method for treating hypogonadism |
| US20020151530A1 (en) * | 2000-12-22 | 2002-10-17 | Leonard Thomas W. | Method of treating hormonal deficiencies in women undergoing estrogen replacement therapy |
| JP5506126B2 (ja) * | 2001-06-18 | 2014-05-28 | ノーヴェン ファーマシューティカルズ インコーポレイテッド | 経皮システムにおける加速した医薬の送達 |
| US7737185B2 (en) * | 2001-07-09 | 2010-06-15 | Repros Therapeutics Inc. | Methods and compositions with trans-clomiphene |
| US7173064B2 (en) * | 2001-07-09 | 2007-02-06 | Repros Therapeutics Inc. | Methods and compositions with trans-clomiphene for treating wasting and lipodystrophy |
| CA2453337C (en) * | 2001-07-09 | 2012-08-28 | Zonagen, Inc. | Methods and materials for the treatment of testosterone deficiency in men |
| WO2003030894A1 (en) * | 2001-10-11 | 2003-04-17 | Alcon, Inc. | Methods for treating dry eye |
| MXPA04003866A (es) * | 2001-11-09 | 2004-07-08 | Pharmacia Ab | Agente-antimuscarnico y agonista de estrogeno para tratar la vejiga inestable o hiperactiva. |
| US20140212508A1 (en) * | 2001-12-20 | 2014-07-31 | John Wayne Kennedy | Copper/zinc superoxide dismutase (sod) formulation for the treatment of traumas including amyotropic lateral sclerosis |
| CA2481310A1 (en) * | 2002-04-03 | 2003-10-16 | Barr Laboratories, Inc. | Step-down estrogen therapy |
| EP1350541A1 (de) * | 2002-04-04 | 2003-10-08 | Jenapharm GmbH & Co. KG | Verwendung von einem Dehydroepiandrosteron und einem Estradiol Derivat zur Herstellung einer pharmazeutischen Zubereitung zur Behandlung klimakterischer Beschwerden in der Postmenopause |
| AU2003221715A1 (en) * | 2002-06-14 | 2003-12-31 | Alcon, Inc. | Use of hydroxyeicosatetraenoic acid compounds to treat vaginal dryness |
| IL152573A (en) | 2002-10-31 | 2009-11-18 | Transpharma Medical Ltd | A system for the transmission through the skin of a medical preparation against vomiting and nausea |
| IL152575A (en) | 2002-10-31 | 2008-12-29 | Transpharma Medical Ltd | A skin-to-skin transmission system of water-insoluble drugs |
| US7858607B2 (en) * | 2003-03-14 | 2010-12-28 | Mamchur Stephen A | System for use by compounding pharmacists to produce hormone replacement medicine customized for each consumer |
| JP4564920B2 (ja) * | 2003-04-18 | 2010-10-20 | 株式会社最先端医学研究所 | 眼に適用する疾患治療剤 |
| IL157535A0 (en) * | 2003-08-21 | 2004-03-28 | Topimed Ltd | Preparations for the prevention of skin atrophy |
| ES2258694T3 (es) | 2003-11-11 | 2006-09-01 | Mattern, Udo | Sistema de administracion de liberacion controlada de hormonas sexuales para aplicaciones nasales. |
| US8784869B2 (en) | 2003-11-11 | 2014-07-22 | Mattern Pharma Ag | Controlled release delivery system for nasal applications and methods of treatment |
| MX2007000050A (es) * | 2004-07-14 | 2007-07-10 | Repros Therapeutics Inc | Trans-clomifeno para el tratamiento de hipertrofia de prostata benigna, cancer de prostata, hipogonadismo, trigliceridos elevados y colesterol elevado. |
| MX368189B (es) | 2004-10-20 | 2019-09-23 | Endorecherche Inc | Precursores esteroides sexuales solos o en combinación con un modulador receptor de estrógeno selectivo y/o con estrógenos y/o con un inhibidor de fosfodiesterasa gmpc de tipo 5 para la prevención y tratamiento de sequedad vaginal y disfunción sexual en mujeres post-menopáusicas. |
| US20150005360A1 (en) | 2004-10-25 | 2015-01-01 | Nse Products, Inc. | Phytoestrogen compositions and associated methods |
| KR20070100811A (ko) * | 2005-02-04 | 2007-10-11 | 레프로스 쎄라피우틱스 아이엔씨. | 남성불임의 치료를 위한 트랜스―클로미펜을 이용한 물질과치료방법 |
| CN101252936A (zh) * | 2005-03-02 | 2008-08-27 | 奈森特医药公司 | 眼用组合物的药学可接受的载体 |
| NZ560551A (en) * | 2005-03-22 | 2010-02-26 | Repros Therapeutics Inc | Dosing regimes for trans-clomiphene |
| EP1908028A1 (en) * | 2005-07-27 | 2008-04-09 | Ingenia Technology Limited | Authenticity verification |
| GB0523550D0 (en) | 2005-11-18 | 2005-12-28 | Hunter Fleming Ltd | Therapeutic uses of steroidal compounds |
| US20080015170A1 (en) * | 2005-12-01 | 2008-01-17 | The Procter & Gamble Company | Method of treating menopausal women transdermally with testosterone |
| JP5193196B2 (ja) | 2006-06-02 | 2013-05-08 | ペア ツリー ウーマンズ ヘルス ケア | 萎縮性膣炎の治療の方法 |
| US20080045486A1 (en) * | 2006-08-17 | 2008-02-21 | Tang-Liu Diane D S | Ocular administration of testosterone |
| RU2480208C2 (ru) | 2006-10-04 | 2013-04-27 | М Унд П Патент Акциенгезелльшафт | Система доставки с контролируемым высвобождением для назального применения нейротрансмиттеров |
| US20080132475A1 (en) * | 2006-12-05 | 2008-06-05 | Charles Gerald Connor | Treatment for dry eye |
| US8268806B2 (en) * | 2007-08-10 | 2012-09-18 | Endorecherche, Inc. | Pharmaceutical compositions |
| ES2718912T3 (es) | 2007-10-16 | 2019-07-05 | Repros Therapeutics Inc | Trans-clomifeno para el tratamiento de la diabetes en hombres hipogonadales |
| US20100016264A1 (en) * | 2007-12-05 | 2010-01-21 | Connor Charles G | Treatment for dry eye using testosterone and progestagen |
| US20090285893A1 (en) * | 2008-05-19 | 2009-11-19 | The Procter & Gamble Company | Treatment of heart failure in women |
| EP2307026B1 (en) * | 2008-07-04 | 2016-04-13 | The Heart Research Institute Limited | The use of androgens for vascular regeneration and endothelial repair |
| US8658628B2 (en) * | 2009-06-18 | 2014-02-25 | Karan Y. Baucom | Hormone delivery system and method |
| US9795617B2 (en) | 2009-06-18 | 2017-10-24 | Baucom Institute for Longevity and Life Enhancement, Inc. | Hormone delivery system and method |
| US9757388B2 (en) | 2011-05-13 | 2017-09-12 | Acerus Pharmaceuticals Srl | Intranasal methods of treating women for anorgasmia with 0.6% and 0.72% testosterone gels |
| AR086400A1 (es) | 2011-05-13 | 2013-12-11 | Trimel Pharmaceuticals Corp | Formulaciones en gel intranasal de testosterona en dosis de menor potencia y uso de las mismas para el tratamiento de la anorgasmia o el trastorno de deseo sexual hipoactivo |
| US20130045958A1 (en) | 2011-05-13 | 2013-02-21 | Trimel Pharmaceuticals Corporation | Intranasal 0.15% and 0.24% testosterone gel formulations and use thereof for treating anorgasmia or hypoactive sexual desire disorder |
| US20130231317A1 (en) * | 2011-07-19 | 2013-09-05 | Michael S. Riepl | Dhea bioadhesive controlled release gel |
| UA113291C2 (xx) | 2011-08-04 | 2017-01-10 | Метаболіти транскломіфену і їх застосування | |
| US9320744B2 (en) | 2011-10-19 | 2016-04-26 | Dhea Llc | DHEA bioadhesive controlled release gel |
| US9301920B2 (en) | 2012-06-18 | 2016-04-05 | Therapeuticsmd, Inc. | Natural combination hormone replacement formulations and therapies |
| RS62297B1 (sr) | 2011-11-23 | 2021-09-30 | Therapeuticsmd Inc | Prirodne kombinovane hormonske supstitucione formulacije i terapije |
| US9713621B2 (en) * | 2012-01-19 | 2017-07-25 | Edward Lichten | Treatment of endometriosis |
| US20130338122A1 (en) | 2012-06-18 | 2013-12-19 | Therapeuticsmd, Inc. | Transdermal hormone replacement therapies |
| US10806740B2 (en) | 2012-06-18 | 2020-10-20 | Therapeuticsmd, Inc. | Natural combination hormone replacement formulations and therapies |
| US20150196640A1 (en) | 2012-06-18 | 2015-07-16 | Therapeuticsmd, Inc. | Progesterone formulations having a desirable pk profile |
| US10806697B2 (en) | 2012-12-21 | 2020-10-20 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| CN104994877A (zh) | 2012-11-02 | 2015-10-21 | 利普生物药剂公司 | 用于癌症治疗的反式-克罗米芬 |
| EP3421043B1 (en) * | 2012-12-05 | 2021-04-07 | GE Nutrients, Inc. | Use of fenugreek extract to enhance female libido |
| US10568891B2 (en) | 2012-12-21 | 2020-02-25 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US10537581B2 (en) | 2012-12-21 | 2020-01-21 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US11266661B2 (en) | 2012-12-21 | 2022-03-08 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US11246875B2 (en) | 2012-12-21 | 2022-02-15 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US9180091B2 (en) | 2012-12-21 | 2015-11-10 | Therapeuticsmd, Inc. | Soluble estradiol capsule for vaginal insertion |
| US10471072B2 (en) | 2012-12-21 | 2019-11-12 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US11744838B2 (en) | 2013-03-15 | 2023-09-05 | Acerus Biopharma Inc. | Methods of treating hypogonadism with transnasal testosterone bio-adhesive gel formulations in male with allergic rhinitis, and methods for preventing an allergic rhinitis event |
| US20140274985A1 (en) * | 2013-03-15 | 2014-09-18 | Raman Malhotra | Systemic administration of androgen in treating dry eye syndrome |
| JP2017516768A (ja) | 2014-05-22 | 2017-06-22 | セラピューティックスエムディー インコーポレーテッドTherapeuticsmd, Inc. | 天然の併用ホルモン補充療法剤及び療法 |
| US10328087B2 (en) | 2015-07-23 | 2019-06-25 | Therapeuticsmd, Inc. | Formulations for solubilizing hormones |
| US10286077B2 (en) | 2016-04-01 | 2019-05-14 | Therapeuticsmd, Inc. | Steroid hormone compositions in medium chain oils |
| US9931349B2 (en) | 2016-04-01 | 2018-04-03 | Therapeuticsmd, Inc. | Steroid hormone pharmaceutical composition |
| WO2019140087A1 (en) | 2018-01-10 | 2019-07-18 | Celista Pharmaceuticals Llc | Testosterone transdermal spray with film |
| EP3817731B1 (en) | 2018-07-05 | 2025-09-03 | Celista Pharmaceuticals Llc | Testosterone and estradiol transdermal spray |
| BE1027858B1 (fr) * | 2019-12-13 | 2021-07-14 | Georges Debled | Composition pharmaceutique pour la contraception chez la femme |
| US11633405B2 (en) | 2020-02-07 | 2023-04-25 | Therapeuticsmd, Inc. | Steroid hormone pharmaceutical formulations |
| TWI893101B (zh) | 2020-04-16 | 2025-08-11 | 比利時商埃斯特拉有限責任公司 | 具有降低之副作用之避孕組成物 |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US550107A (en) * | 1895-11-19 | Thirds to henry zervas and julius wegert | ||
| US4210664A (en) | 1979-03-02 | 1980-07-01 | Merrell Toraude Et Compagnie | Use of α,α'-dithiobis(β-arylacrylic acid) derivatives to enhance zinc serum and tissue concentrations |
| FR2573307B1 (fr) * | 1984-11-22 | 1988-06-10 | Virbac Ctre Rech Biolog | Implants anabolisants a liberation prolongee |
| US4849224A (en) | 1987-11-12 | 1989-07-18 | Theratech Inc. | Device for administering an active agent to the skin or mucosa |
| US4983395A (en) | 1987-11-12 | 1991-01-08 | Theratech Inc. | Device for administering an active agent to the skin or mucosa |
| NZ244499A (en) | 1989-03-10 | 1999-05-28 | Endorecherche Inc | Treating breast or endometrial cancer with antiestrogen plus one of an androgen, a progestin and an inhibitor of sex steroid formation or secretion of prolactin, growth hormone or acth |
| US5122383A (en) | 1991-05-17 | 1992-06-16 | Theratech, Inc. | Sorbitan esters as skin permeation enhancers |
| US5152997A (en) | 1990-12-11 | 1992-10-06 | Theratech, Inc. | Method and device for transdermally administering testosterone across nonscrotal skin at therapeutically effective levels |
| US5340586A (en) * | 1991-04-12 | 1994-08-23 | University Of Southern California | Methods and formulations for use in treating oophorectomized women |
| ES2261836T3 (es) * | 1993-01-19 | 2006-11-16 | Endorecherche Inc. | Usos terapeuticos de dehidroepiandrosterona para tratamiento de libido disminuida y osteoporosis. |
| US5460820B1 (en) * | 1993-08-03 | 1999-08-03 | Theratech Inc | Method for providing testosterone and optionally estrogen replacement therapy to women |
| ES2098193B1 (es) * | 1995-07-21 | 1997-12-01 | Gomez Jesus Calderon | Nueva formulacion farmaceutica de dehidroepiandrosterona para aplicacion topica percutanea. |
| US5770226A (en) * | 1996-07-10 | 1998-06-23 | Wake Forest University | Combined pharmaceutical estrogen-androgen-progestin oral contraceptive |
| US6139873A (en) * | 1996-07-10 | 2000-10-31 | Cedars-Sinai Medical Center | Combined pharmaceutical estrogen-androgen-progestin |
| US6228852B1 (en) * | 1996-07-12 | 2001-05-08 | Carolyn V. Shaak | Transdermal application of naturally occurring steroid hormones |
| US5855920A (en) * | 1996-12-13 | 1999-01-05 | Chein; Edmund Y. M. | Total hormone replacement therapy |
| HUP0102483A3 (en) | 1998-06-11 | 2002-11-28 | Endorech Inc Sainte Foy | Pharmaceutical compositions containing androst-5-ene-3betha,17betha-diol |
| US6465445B1 (en) | 1998-06-11 | 2002-10-15 | Endorecherche, Inc. | Medical uses of a selective estrogen receptor modulator in combination with sex steroid precursors |
| CO5180583A1 (es) * | 1999-06-11 | 2002-07-30 | Watson Pharmaceuticals Inc | Administracion de esteroides androgenicos no orales a las mujeres |
-
2000
- 2000-06-09 CO CO00043097A patent/CO5180583A1/es not_active Application Discontinuation
- 2000-06-09 IL IL14701000A patent/IL147010A0/xx unknown
- 2000-06-09 TR TR2002/00406T patent/TR200200406T2/xx unknown
- 2000-06-09 CZ CZ20014499A patent/CZ299198B6/cs not_active IP Right Cessation
- 2000-06-09 JP JP2001502855A patent/JP5184727B2/ja not_active Expired - Lifetime
- 2000-06-09 HU HU0301813A patent/HUP0301813A2/hu unknown
- 2000-06-09 SK SK1821-2001A patent/SK18212001A3/sk unknown
- 2000-06-09 PE PE2000000580A patent/PE20010404A1/es not_active Application Discontinuation
- 2000-06-09 US US09/591,141 patent/US6583129B1/en not_active Expired - Lifetime
- 2000-06-09 EP EP00939710A patent/EP1189619A4/en not_active Ceased
- 2000-06-09 CA CA2376797A patent/CA2376797C/en not_active Expired - Lifetime
- 2000-06-09 HK HK03100572.3A patent/HK1048269B/zh not_active IP Right Cessation
- 2000-06-09 NZ NZ516502A patent/NZ516502A/xx unknown
- 2000-06-09 TW TW089111386A patent/TWI281398B/zh not_active IP Right Cessation
- 2000-06-09 BR BR0011740-4A patent/BR0011740A/pt not_active Application Discontinuation
- 2000-06-09 KR KR1020017015926A patent/KR20020011437A/ko not_active Ceased
- 2000-06-09 PL PL00352250A patent/PL352250A1/xx not_active IP Right Cessation
- 2000-06-09 AU AU54758/00A patent/AU775145B2/en not_active Ceased
- 2000-06-09 MX MXPA01012769A patent/MXPA01012769A/es active IP Right Grant
- 2000-06-09 CN CNB008111642A patent/CN1220491C/zh not_active Expired - Fee Related
- 2000-06-09 KR KR1020077012765A patent/KR20070063609A/ko not_active Ceased
- 2000-06-09 WO PCT/US2000/015834 patent/WO2000076522A1/en not_active Ceased
- 2000-06-12 MY MYPI20002645 patent/MY126960A/en unknown
- 2000-06-12 AR ARP000102889A patent/AR024566A1/es unknown
- 2000-09-30 SA SA00210404A patent/SA00210404B1/ar unknown
-
2001
- 2001-12-11 NO NO20016046A patent/NO20016046L/no not_active Application Discontinuation
-
2002
- 2002-10-22 US US10/278,033 patent/US7186706B2/en not_active Expired - Lifetime
-
2007
- 2007-02-15 US US11/707,568 patent/US8551516B2/en not_active Expired - Fee Related
-
2012
- 2012-10-11 JP JP2012225943A patent/JP2013049682A/ja active Pending
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