JP2003501439A - ６−ｏ−カルバメートケトライド誘導体 - Google Patents

６−ｏ−カルバメートケトライド誘導体

Info

Publication number
JP2003501439A
JP2003501439A JP2001502437A JP2001502437A JP2003501439A JP 2003501439 A JP2003501439 A JP 2003501439A JP 2001502437 A JP2001502437 A JP 2001502437A JP 2001502437 A JP2001502437 A JP 2001502437A JP 2003501439 A JP2003501439 A JP 2003501439A
Authority
JP
Japan
Prior art keywords
formula
aryl
compound
group
heteroaryl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2001502437A
Other languages
English (en)
Japanese (ja)
Other versions
JP2003501439A5 (enExample
Inventor
フアン，リイ・テイ
オア，ヤツト・サン
マア，チエンクン
チエン，ヤン
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Abbott Laboratories
Original Assignee
Abbott Laboratories
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Laboratories filed Critical Abbott Laboratories
Publication of JP2003501439A publication Critical patent/JP2003501439A/ja
Publication of JP2003501439A5 publication Critical patent/JP2003501439A5/ja
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Cephalosporin Compounds (AREA)
JP2001502437A 1999-06-07 2000-05-31 ６−ｏ−カルバメートケトライド誘導体 Pending JP2003501439A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US32778499A 1999-06-07 1999-06-07
US09/327,784 1999-06-07
PCT/US2000/014923 WO2000075156A1 (en) 1999-06-07 2000-05-31 6-o-carbamate ketolide derivatives

Publications (2)

Publication Number Publication Date
JP2003501439A true JP2003501439A (ja) 2003-01-14
JP2003501439A5 JP2003501439A5 (enExample) 2007-06-21

Family

ID=23278051

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2001502437A Pending JP2003501439A (ja) 1999-06-07 2000-05-31 ６−ｏ−カルバメートケトライド誘導体

Country Status (10)

Country Link
EP (1) EP1181300B1 (enExample)
JP (1) JP2003501439A (enExample)
AT (1) ATE250076T1 (enExample)
CA (1) CA2378671C (enExample)
DE (1) DE60005334T2 (enExample)
DK (1) DK1181300T3 (enExample)
ES (1) ES2208334T3 (enExample)
MX (1) MXPA01012661A (enExample)
PT (1) PT1181300E (enExample)
WO (1) WO2000075156A1 (enExample)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2002542197A (ja) 1999-04-16 2002-12-10 オーソ−マクニール・フアーマシユーチカル・インコーポレーテツド ケトライド抗菌剤
US6590083B1 (en) 1999-04-16 2003-07-08 Ortho-Mcneil Pharmaceutical, Inc. Ketolide antibacterials
EP1146051A3 (en) * 2000-04-10 2001-10-31 Pfizer Products Inc. Erythromycin A derivatives
US6472372B1 (en) 2000-12-06 2002-10-29 Ortho-Mcneil Pharmaceuticals, Inc. 6-O-Carbamoyl ketolide antibacterials
WO2003024986A1 (en) * 2001-09-17 2003-03-27 Ortho-Mcneil Pharmaceutical, Inc. 6-o-carbamate-11,12-lacto-ketolide antimicrobials
CA2469304A1 (en) 2001-12-05 2003-06-19 Ortho-Mcneil Pharmaceutical, Inc. 6-o acyl ketolide antibacterials
WO2003102010A1 (en) * 2002-05-31 2003-12-11 Janssen Pharmaceutica N.V. 3-descladinosyl-6-o-carbamoyl and 6-o-carbonoyl macrolide antibacterial agents

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6284095A (ja) * 1985-08-28 1987-04-17 ビ−チヤム・グル−プ・ピ−エルシ− 新規化合物、その製法及びそれを含む医薬組成物
JPH04290893A (ja) * 1990-11-21 1992-10-15 Roussel Uclaf 新規なエリスロマイシン誘導体、その製造法、得られる新規な中間体及びそれらの薬剤としての使用
WO1998009978A1 (en) * 1996-09-04 1998-03-12 Abbott Laboratories 6-o-substituted ketolides having antibacterial activity
WO1998018808A1 (fr) * 1996-10-31 1998-05-07 Taisho Pharmaceutical Co., Ltd. Derives de l'erythromycine
WO1998054197A1 (en) * 1997-05-29 1998-12-03 Abbott Laboratories Multicyclic erythromycin derivatives
WO1998056800A1 (en) * 1997-06-11 1998-12-17 Pfizer Products Inc. 9-oxime erythromycin derivatives

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5750510A (en) * 1997-04-04 1998-05-12 Abbott Laboratories 3-descladinose-2,3-anhydroerythromycin derivatives

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6284095A (ja) * 1985-08-28 1987-04-17 ビ−チヤム・グル−プ・ピ−エルシ− 新規化合物、その製法及びそれを含む医薬組成物
JPH04290893A (ja) * 1990-11-21 1992-10-15 Roussel Uclaf 新規なエリスロマイシン誘導体、その製造法、得られる新規な中間体及びそれらの薬剤としての使用
WO1998009978A1 (en) * 1996-09-04 1998-03-12 Abbott Laboratories 6-o-substituted ketolides having antibacterial activity
WO1998018808A1 (fr) * 1996-10-31 1998-05-07 Taisho Pharmaceutical Co., Ltd. Derives de l'erythromycine
WO1998054197A1 (en) * 1997-05-29 1998-12-03 Abbott Laboratories Multicyclic erythromycin derivatives
WO1998056800A1 (en) * 1997-06-11 1998-12-17 Pfizer Products Inc. 9-oxime erythromycin derivatives

Also Published As

Publication number Publication date
WO2000075156A1 (en) 2000-12-14
ATE250076T1 (de) 2003-10-15
DK1181300T3 (da) 2004-01-26
DE60005334T2 (de) 2004-06-24
MXPA01012661A (es) 2002-07-22
EP1181300A1 (en) 2002-02-27
CA2378671A1 (en) 2000-12-14
PT1181300E (pt) 2004-02-27
ES2208334T3 (es) 2004-06-16
EP1181300B1 (en) 2003-09-17
DE60005334D1 (de) 2003-10-23
CA2378671C (en) 2007-04-24

Similar Documents

Publication Publication Date Title
US6046171A (en) 6,11-bridged erythromycin derivatives
WO1997042204A1 (en) 6-o-substituted erythromycins and method for making them
JP2004520314A (ja) マクロライド抗生物質
EP1027361B1 (en) 6,11-bridged erythromycin derivatives
EP0922050B1 (en) 3-descladinose-2,3-anhydroerythromycin derivatives
US6420535B1 (en) 6-O-carbamate ketolide derivatives
KR20010023756A (ko) 6,9-브리지된 에리트로마이신 유도체
US6946446B2 (en) Anti-infective agents useful against multidrug-resistant strains of bacteria
EP1206476B1 (en) 9a-azalides with antibacterial activity
JP2003501439A (ja) ６−ｏ−カルバメートケトライド誘導体
JP2003501439A5 (enExample)
JP2001515844A (ja) ３−デスクラジノース６−ｏ−置換エリスロマイシン誘導体
US5747466A (en) 3-deoxy-3-descladinose derivatives of erythromycins A and B
US6569836B2 (en) 6-O-alkyl-2-nor-2-substituted ketolide derivatives
CA2391297C (en) 6-o-alkyl-2-nor-2-substituted ketolide derivatives
CA2398848C (en) Anti-infective agents useful against multidrug-resistant strains of bacteria
AU714176B2 (en) 3-deoxy-3-descladinose derivatives of erythromycins A and B
JP4368950B2 (ja) 多環式エリスロマイシン誘導体
MXPA00002216A (en) 3-descladinose 6-o-substituded erythromycin derivatives
MXPA00004227A (en) 6,11-bridged erythromycin derivatives
CZ20001394A3 (cs) Erythromycinové deriváty s 6,11-přemostěním

Legal Events

Date Code Title Description
A524 Written submission of copy of amendment under article 19 pct

Free format text: JAPANESE INTERMEDIATE CODE: A524

Effective date: 20070423

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20070423

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20100921

A02 Decision of refusal

Free format text: JAPANESE INTERMEDIATE CODE: A02

Effective date: 20110301