JP2003250589A - 呼吸器系ウイルスの検出 - Google Patents
呼吸器系ウイルスの検出Info
- Publication number
- JP2003250589A JP2003250589A JP2002376303A JP2002376303A JP2003250589A JP 2003250589 A JP2003250589 A JP 2003250589A JP 2002376303 A JP2002376303 A JP 2002376303A JP 2002376303 A JP2002376303 A JP 2002376303A JP 2003250589 A JP2003250589 A JP 2003250589A
- Authority
- JP
- Japan
- Prior art keywords
- seq
- nos
- primer pair
- pair
- nucleic acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 210000002345 respiratory system Anatomy 0.000 title claims abstract 3
- 230000010460 detection of virus Effects 0.000 title claims description 3
- 150000007523 nucleic acids Chemical group 0.000 claims abstract description 84
- 108020004707 nucleic acids Proteins 0.000 claims abstract description 80
- 102000039446 nucleic acids Human genes 0.000 claims abstract description 80
- 241000700605 Viruses Species 0.000 claims abstract description 72
- 241000701161 unidentified adenovirus Species 0.000 claims abstract description 24
- 241001559187 Human rubulavirus 2 Species 0.000 claims abstract description 23
- 241000712003 Human respirovirus 3 Species 0.000 claims abstract description 20
- 241000726041 Human respirovirus 1 Species 0.000 claims abstract description 18
- 238000000034 method Methods 0.000 claims abstract description 15
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- 108091034117 Oligonucleotide Proteins 0.000 claims description 76
- 230000003321 amplification Effects 0.000 claims description 69
- 238000003199 nucleic acid amplification method Methods 0.000 claims description 69
- JLCPHMBAVCMARE-UHFFFAOYSA-N [3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-[[3-[[3-[[3-[[3-[[3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-hydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methyl [5-(6-aminopurin-9-yl)-2-(hydroxymethyl)oxolan-3-yl] hydrogen phosphate Polymers Cc1cn(C2CC(OP(O)(=O)OCC3OC(CC3OP(O)(=O)OCC3OC(CC3O)n3cnc4c3nc(N)[nH]c4=O)n3cnc4c3nc(N)[nH]c4=O)C(COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3CO)n3cnc4c(N)ncnc34)n3ccc(N)nc3=O)n3cnc4c(N)ncnc34)n3ccc(N)nc3=O)n3ccc(N)nc3=O)n3ccc(N)nc3=O)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cc(C)c(=O)[nH]c3=O)n3cc(C)c(=O)[nH]c3=O)n3ccc(N)nc3=O)n3cc(C)c(=O)[nH]c3=O)n3cnc4c3nc(N)[nH]c4=O)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)O2)c(=O)[nH]c1=O JLCPHMBAVCMARE-UHFFFAOYSA-N 0.000 claims description 30
- 101710133291 Hemagglutinin-neuraminidase Proteins 0.000 claims description 21
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- 241000712431 Influenza A virus Species 0.000 claims description 17
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- 101710154606 Hemagglutinin Proteins 0.000 claims description 4
- 101710093908 Outer capsid protein VP4 Proteins 0.000 claims description 4
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- 208000002606 Paramyxoviridae Infections Diseases 0.000 claims description 4
- 101710176177 Protein A56 Proteins 0.000 claims description 4
- 206010057190 Respiratory tract infections Diseases 0.000 claims description 3
- 239000000185 hemagglutinin Substances 0.000 claims description 3
- 241001500351 Influenzavirus A Species 0.000 claims description 2
- 230000004927 fusion Effects 0.000 claims description 2
- 108700026758 Adenovirus hexon capsid Proteins 0.000 claims 4
- FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 claims 1
- 108010006232 Neuraminidase Proteins 0.000 claims 1
- 208000037798 influenza B Diseases 0.000 claims 1
- 230000000241 respiratory effect Effects 0.000 abstract description 25
- 208000015181 infectious disease Diseases 0.000 abstract description 2
- 206010022000 influenza Diseases 0.000 abstract 2
- 241000701076 Macacine alphaherpesvirus 1 Species 0.000 abstract 1
- 108091028043 Nucleic acid sequence Proteins 0.000 abstract 1
- 210000000056 organ Anatomy 0.000 abstract 1
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- 229920000642 polymer Polymers 0.000 description 10
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- 230000003612 virological effect Effects 0.000 description 9
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- YBJHBAHKTGYVGT-ZKWXMUAHSA-N (+)-Biotin Chemical compound N1C(=O)N[C@@H]2[C@H](CCCCC(=O)O)SC[C@@H]21 YBJHBAHKTGYVGT-ZKWXMUAHSA-N 0.000 description 4
- UCSJYZPVAKXKNQ-HZYVHMACSA-N streptomycin Chemical compound CN[C@H]1[C@H](O)[C@@H](O)[C@H](CO)O[C@H]1O[C@@H]1[C@](C=O)(O)[C@H](C)O[C@H]1O[C@@H]1[C@@H](NC(N)=N)[C@H](O)[C@@H](NC(N)=N)[C@H](O)[C@H]1O UCSJYZPVAKXKNQ-HZYVHMACSA-N 0.000 description 4
- 101100221553 Escherichia coli (strain K12) copA gene Proteins 0.000 description 3
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- 238000003757 reverse transcription PCR Methods 0.000 description 3
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- 239000011534 wash buffer Substances 0.000 description 3
- NFIVJOSXJDORSP-UHFFFAOYSA-N 2-azaniumyl-3-(4-boronophenyl)propanoate Chemical compound OC(=O)C(N)CC1=CC=C(B(O)O)C=C1 NFIVJOSXJDORSP-UHFFFAOYSA-N 0.000 description 2
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- 108010014303 DNA-directed DNA polymerase Proteins 0.000 description 2
- 102000016928 DNA-directed DNA polymerase Human genes 0.000 description 2
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- 101710094396 Hexon protein Proteins 0.000 description 2
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- JGSARLDLIJGVTE-MBNYWOFBSA-N Penicillin G Chemical group N([C@H]1[C@H]2SC([C@@H](N2C1=O)C(O)=O)(C)C)C(=O)CC1=CC=CC=C1 JGSARLDLIJGVTE-MBNYWOFBSA-N 0.000 description 2
- IQFYYKKMVGJFEH-XLPZGREQSA-N Thymidine Chemical compound O=C1NC(=O)C(C)=CN1[C@@H]1O[C@H](CO)[C@@H](O)C1 IQFYYKKMVGJFEH-XLPZGREQSA-N 0.000 description 2
- 239000011543 agarose gel Substances 0.000 description 2
- 229960002685 biotin Drugs 0.000 description 2
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- 238000013461 design Methods 0.000 description 2
- 238000013467 fragmentation Methods 0.000 description 2
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- 229940049954 penicillin Drugs 0.000 description 2
- 102000054765 polymorphisms of proteins Human genes 0.000 description 2
- 238000002360 preparation method Methods 0.000 description 2
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- 238000011160 research Methods 0.000 description 2
- 108091008146 restriction endonucleases Proteins 0.000 description 2
- 238000010839 reverse transcription Methods 0.000 description 2
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- 229960005322 streptomycin Drugs 0.000 description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 2
- QKNYBSVHEMOAJP-UHFFFAOYSA-N 2-amino-2-(hydroxymethyl)propane-1,3-diol;hydron;chloride Chemical compound Cl.OCC(N)(CO)CO QKNYBSVHEMOAJP-UHFFFAOYSA-N 0.000 description 1
- 102000002260 Alkaline Phosphatase Human genes 0.000 description 1
- 108020004774 Alkaline Phosphatase Proteins 0.000 description 1
- DWRXFEITVBNRMK-UHFFFAOYSA-N Beta-D-1-Arabinofuranosylthymine Natural products O=C1NC(=O)C(C)=CN1C1C(O)C(O)C(CO)O1 DWRXFEITVBNRMK-UHFFFAOYSA-N 0.000 description 1
- 208000035473 Communicable disease Diseases 0.000 description 1
- SHIBSTMRCDJXLN-UHFFFAOYSA-N Digoxigenin Natural products C1CC(C2C(C3(C)CCC(O)CC3CC2)CC2O)(O)C2(C)C1C1=CC(=O)OC1 SHIBSTMRCDJXLN-UHFFFAOYSA-N 0.000 description 1
- KCXVZYZYPLLWCC-UHFFFAOYSA-N EDTA Chemical compound OC(=O)CN(CC(O)=O)CCN(CC(O)=O)CC(O)=O KCXVZYZYPLLWCC-UHFFFAOYSA-N 0.000 description 1
- 241000588724 Escherichia coli Species 0.000 description 1
- 101150008820 HN gene Proteins 0.000 description 1
- 241001500350 Influenzavirus B Species 0.000 description 1
- NTIZESTWPVYFNL-UHFFFAOYSA-N Methyl isobutyl ketone Chemical compound CC(C)CC(C)=O NTIZESTWPVYFNL-UHFFFAOYSA-N 0.000 description 1
- 239000000020 Nitrocellulose Substances 0.000 description 1
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- 208000036142 Viral infection Diseases 0.000 description 1
- 230000001154 acute effect Effects 0.000 description 1
- 239000011324 bead Substances 0.000 description 1
- IQFYYKKMVGJFEH-UHFFFAOYSA-N beta-L-thymidine Natural products O=C1NC(=O)C(C)=CN1C1OC(CO)C(O)C1 IQFYYKKMVGJFEH-UHFFFAOYSA-N 0.000 description 1
- 239000012472 biological sample Substances 0.000 description 1
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- QONQRTHLHBTMGP-UHFFFAOYSA-N digitoxigenin Natural products CC12CCC(C3(CCC(O)CC3CC3)C)C3C11OC1CC2C1=CC(=O)OC1 QONQRTHLHBTMGP-UHFFFAOYSA-N 0.000 description 1
- SHIBSTMRCDJXLN-KCZCNTNESA-N digoxigenin Chemical compound C1([C@@H]2[C@@]3([C@@](CC2)(O)[C@H]2[C@@H]([C@@]4(C)CC[C@H](O)C[C@H]4CC2)C[C@H]3O)C)=CC(=O)OC1 SHIBSTMRCDJXLN-KCZCNTNESA-N 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
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- ZMMJGEGLRURXTF-UHFFFAOYSA-N ethidium bromide Chemical compound [Br-].C12=CC(N)=CC=C2C2=CC=C(N)C=C2[N+](CC)=C1C1=CC=CC=C1 ZMMJGEGLRURXTF-UHFFFAOYSA-N 0.000 description 1
- 229960005542 ethidium bromide Drugs 0.000 description 1
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- GNBHRKFJIUUOQI-UHFFFAOYSA-N fluorescein Chemical compound O1C(=O)C2=CC=CC=C2C21C1=CC=C(O)C=C1OC1=CC(O)=CC=C21 GNBHRKFJIUUOQI-UHFFFAOYSA-N 0.000 description 1
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- 238000012986 modification Methods 0.000 description 1
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- 229920001220 nitrocellulos Polymers 0.000 description 1
- 238000001821 nucleic acid purification Methods 0.000 description 1
- 229920001778 nylon Polymers 0.000 description 1
- 229920000656 polylysine Polymers 0.000 description 1
- 230000002265 prevention Effects 0.000 description 1
- 208000023504 respiratory system disease Diseases 0.000 description 1
- PYWVYCXTNDRMGF-UHFFFAOYSA-N rhodamine B Chemical compound [Cl-].C=12C=CC(=[N+](CC)CC)C=C2OC2=CC(N(CC)CC)=CC=C2C=1C1=CC=CC=C1C(O)=O PYWVYCXTNDRMGF-UHFFFAOYSA-N 0.000 description 1
- YGSDEFSMJLZEOE-UHFFFAOYSA-N salicylic acid Chemical compound OC(=O)C1=CC=CC=C1O YGSDEFSMJLZEOE-UHFFFAOYSA-N 0.000 description 1
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
- C12Q1/701—Specific hybridization probes
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Virology (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10/038,835 US6881835B2 (en) | 2002-01-04 | 2002-01-04 | Detection of respiratory viruses |
| US10/038,835 | 2002-01-04 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2003250589A true JP2003250589A (ja) | 2003-09-09 |
| JP2003250589A5 JP2003250589A5 (enExample) | 2005-12-22 |
Family
ID=21902169
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2002376303A Pending JP2003250589A (ja) | 2002-01-04 | 2002-12-26 | 呼吸器系ウイルスの検出 |
Country Status (3)
| Country | Link |
|---|---|
| US (1) | US6881835B2 (enExample) |
| EP (1) | EP1327691A3 (enExample) |
| JP (1) | JP2003250589A (enExample) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2020533974A (ja) * | 2017-08-31 | 2020-11-26 | イオニアン・テクノロジーズ・エル・エル・シー | 呼吸器合胞体ウイルス種のニッキング及び伸長増幅反応（ｎｅａｒ） |
Families Citing this family (40)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8032310B2 (en) | 2004-07-02 | 2011-10-04 | The United States Of America As Represented By The Secretary Of The Navy | Computer-implemented method, computer readable storage medium, and apparatus for identification of a biological sequence |
| US7695941B2 (en) * | 2005-06-16 | 2010-04-13 | The United States Of America As Represented By The Secretary Of The Navy | Multiplexed polymerase chain reaction for genetic sequence analysis |
| ES2303395B1 (es) * | 2004-12-24 | 2009-05-29 | Instituto De Salud Carlos Iii | Sondas y metodos para la deteccion e identificacion simultanea de multiples virus causantes de infecciones respiratorias en humanos. |
| KR100738082B1 (ko) * | 2004-12-24 | 2007-07-12 | 삼성전자주식회사 | 핵산 프라이머 세트, 핵산 프로브 세트 및 그들을 이용한호흡기 질환 바이러스의 검출방법 |
| DK2230304T3 (da) | 2005-01-07 | 2012-07-16 | Alnylam Pharmaceuticals Inc | IRNA-modulering af RSV og terapeutiske anvendelser deraf |
| US8124335B2 (en) * | 2005-05-06 | 2012-02-28 | Gen-Probe Incorporated | Compositions and assays to detect influenza virus A and B nucleic acids |
| US7785786B2 (en) | 2006-01-23 | 2010-08-31 | Quest Diagnostics Investments Incorporated | Methods for detecting nucleic acids using multiple signals |
| EP1843158A1 (de) * | 2006-04-05 | 2007-10-10 | Micronas Holding GmbH | Nachweissystem für Krankheitserreger |
| US20090098527A1 (en) * | 2006-09-12 | 2009-04-16 | Fischer Gerald W | Biological organism identification product and methods |
| US8097419B2 (en) | 2006-09-12 | 2012-01-17 | Longhorn Vaccines & Diagnostics Llc | Compositions and method for rapid, real-time detection of influenza A virus (H1N1) swine 2009 |
| US8652782B2 (en) | 2006-09-12 | 2014-02-18 | Longhorn Vaccines & Diagnostics, Llc | Compositions and methods for detecting, identifying and quantitating mycobacterial-specific nucleic acids |
| US9481912B2 (en) | 2006-09-12 | 2016-11-01 | Longhorn Vaccines And Diagnostics, Llc | Compositions and methods for detecting and identifying nucleic acid sequences in biological samples |
| US8080645B2 (en) | 2007-10-01 | 2011-12-20 | Longhorn Vaccines & Diagnostics Llc | Biological specimen collection/transport compositions and methods |
| KR100832860B1 (ko) | 2006-12-15 | 2008-05-30 | 대한민국 | 호흡기 바이러스 검출용 올리고뉴클레오타이드 및 ｄｎａ칩 |
| FR2918995B1 (fr) * | 2007-07-19 | 2013-02-08 | Centre Nat Rech Scient | Variants de hpiv-2,et leurs applications medicales |
| US9683256B2 (en) | 2007-10-01 | 2017-06-20 | Longhorn Vaccines And Diagnostics, Llc | Biological specimen collection and transport system |
| US11041215B2 (en) | 2007-08-24 | 2021-06-22 | Longhorn Vaccines And Diagnostics, Llc | PCR ready compositions and methods for detecting and identifying nucleic acid sequences |
| WO2009029686A1 (en) | 2007-08-27 | 2009-03-05 | Longhorn Vaccines & Diagnostics Llc | Immunogenic compositions and methods |
| US10004799B2 (en) | 2007-08-27 | 2018-06-26 | Longhorn Vaccines And Diagnostics, Llc | Composite antigenic sequences and vaccines |
| US11041216B2 (en) | 2007-10-01 | 2021-06-22 | Longhorn Vaccines And Diagnostics, Llc | Compositions and methods for detecting and quantifying nucleic acid sequences in blood samples |
| DK2195466T3 (da) * | 2007-10-01 | 2013-01-14 | Longhorn Vaccines & Diagnostics Llc | Fremgangsmåde til opbevaring af biologiske prøver |
| WO2009102369A2 (en) * | 2007-11-20 | 2009-08-20 | Autogenomics, Inc. | Multiplex assay for respiratory viruses |
| AU2008334948B2 (en) * | 2007-12-13 | 2014-11-20 | Alnylam Pharmaceuticals, Inc. | Methods and compositions for prevention or treatment of RSV infection |
| US8354230B2 (en) | 2007-12-21 | 2013-01-15 | Quest Diagnostics Investments Inc. | Multiplex detection assay for influenza and RSV viruses |
| EP2268801A4 (en) * | 2008-03-14 | 2011-12-28 | Us Gov Health & Human Serv | COMPOSITIONS AND METHODS RELATED TO A HUMAN BOCAVIRUS |
| US20100168205A1 (en) * | 2008-10-23 | 2010-07-01 | Alnylam Pharmaceuticals, Inc. | Methods and Compositions for Prevention or Treatment of RSV Infection Using Modified Duplex RNA Molecules |
| US20100181626A1 (en) * | 2009-01-21 | 2010-07-22 | Jing-Cheng Lin | Methods for Forming NMOS and PMOS Devices on Germanium-Based Substrates |
| EP2314720A1 (en) | 2009-10-20 | 2011-04-27 | Assistance Publique Hôpitaux De Paris | Detection of respiratory viruses |
| ES2541710T3 (es) * | 2009-11-03 | 2015-07-23 | Sva Statens Veterinärmedicinska Anstalt | Procedimiento de genotipado |
| EP3674423A1 (en) | 2010-07-12 | 2020-07-01 | Gen-Probe Incorporated | Compositions and assays to detect seasonal h3 influenza a virus nucleic acid |
| EP2729584A4 (en) * | 2011-07-06 | 2015-03-04 | Intelligent Med Devices Inc | OPTIMIZED PROBES AND PRIMERS AND METHODS OF USE FOR THE BINDING, DETECTION, DIFFERENTIATION, ISOLATION AND SEQUENCING OF INFLUENZA VIRUS, INFLUENZA VIRUSES AND SYNCYTIAL RESPIRATORY VIRUSES |
| CN104203272A (zh) | 2012-01-26 | 2014-12-10 | 长角牛疫苗和诊断有限责任公司 | 复合抗原序列及疫苗 |
| CN103399148B (zh) * | 2013-08-06 | 2015-09-30 | 西南大学 | 基于纳米金信号放大的人呼吸道合胞病毒检测试剂盒 |
| WO2016183292A1 (en) | 2015-05-14 | 2016-11-17 | Longhorn Vaccines And Diagnostics, Llc | Rapid methods for the extraction of nucleic acids from biological samples |
| CN110172529A (zh) * | 2019-05-21 | 2019-08-27 | 上海星耀医学科技发展有限公司 | 一种呼吸道病毒核酸联合检测试剂盒及检测方法 |
| CN110964853B (zh) * | 2019-12-19 | 2023-06-02 | 武汉中帜生物科技股份有限公司 | 一种基于双扩增技术联合检测呼吸道合胞病毒、副流感病毒及腺病毒的试剂盒及其应用 |
| CN110964854B (zh) * | 2019-12-19 | 2021-09-03 | 武汉中帜生物科技股份有限公司 | 用于同时检测七项呼吸道病原体核酸的试剂盒及其应用 |
| RU2733379C1 (ru) * | 2019-12-23 | 2020-10-01 | Федеральное государственное бюджетное учреждение "Научно-исследовательский институт гриппа имени А.А. Смородинцева" Министерства здравоохранения Российской Федерации | Тест-система для диагностики возбудителей острых респираторных вирусных инфекций |
| KR20230107609A (ko) * | 2020-11-12 | 2023-07-17 | 머크 샤프 앤드 돔 엘엘씨 | 항-호흡기 세포융합 바이러스 (rsv) 항체 세포-기반 역가 검정 |
| CN114891924A (zh) * | 2022-03-31 | 2022-08-12 | 杭州丹威生物科技有限公司 | 一种ⅰ型副流感病毒、ⅲ型副流感病毒和腺病毒的多重富集检测方法 |
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| US5401626A (en) | 1989-06-18 | 1995-03-28 | Fujikura Kasei Co., Ltd. | cDNA fragment of the gene for the hemagglutinin neuraminidase of human parainfluenza type 2 virus and materials containing the cDNA fragment |
| DE3929144A1 (de) | 1989-09-02 | 1991-03-07 | Behringwerke Ag | Nachweis von influenza-a-virus durch polymerase-kettenreaktion (pcr) nach reverser transkription eines bereichs des viralen haemagglutinin-gens |
| US5374717A (en) * | 1992-09-30 | 1994-12-20 | The United States Of America As Represented By The Secretary Of Health And Human Services | Sequences of the hemagglutinins of recent strains of influenza type B virus |
| US5744299A (en) | 1995-11-03 | 1998-04-28 | Mcw Research Foundation | Human parainfluenza virus-1 assay |
| US6015664A (en) | 1995-11-03 | 2000-01-18 | Mcw Research Foundation | Multiplex PCR assay using unequal primer concentrations to detect HPIV 1,2,3 and RSV A,B and influenza virus A, B |
| DE69939388D1 (de) | 1998-09-24 | 2008-10-02 | Innogenetics Nv | Identizierung von microorganismen,die akute atemwegsinfektionen verursachen |
| AU1771901A (en) * | 1999-11-16 | 2001-05-30 | Apollo Biotechnology, Inc. | Method for rapid and accurate identification of microorganisms |
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- 2002-12-04 EP EP02026942A patent/EP1327691A3/en not_active Ceased
- 2002-12-26 JP JP2002376303A patent/JP2003250589A/ja active Pending
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2020533974A (ja) * | 2017-08-31 | 2020-11-26 | イオニアン・テクノロジーズ・エル・エル・シー | 呼吸器合胞体ウイルス種のニッキング及び伸長増幅反応（ｎｅａｒ） |
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| US6881835B2 (en) | 2005-04-19 |
| US20030130497A1 (en) | 2003-07-10 |
| EP1327691A2 (en) | 2003-07-16 |
| EP1327691A3 (en) | 2004-03-10 |
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