JP2003185668A5 - - Google Patents
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- JP2003185668A5 JP2003185668A5 JP2002298010A JP2002298010A JP2003185668A5 JP 2003185668 A5 JP2003185668 A5 JP 2003185668A5 JP 2002298010 A JP2002298010 A JP 2002298010A JP 2002298010 A JP2002298010 A JP 2002298010A JP 2003185668 A5 JP2003185668 A5 JP 2003185668A5
- Authority
- JP
- Japan
- Prior art keywords
- analyte
- ligand
- detection
- capture
- tethered
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 238000000034 method Methods 0.000 claims 74
- 239000012491 analyte Substances 0.000 claims 60
- 239000003446 ligand Substances 0.000 claims 45
- 238000001514 detection method Methods 0.000 claims 26
- 239000000985 reactive dye Substances 0.000 claims 16
- 239000000758 substrate Substances 0.000 claims 9
- 125000000524 functional group Chemical group 0.000 claims 6
- -1 heme compound Chemical class 0.000 claims 5
- 238000002835 absorbance Methods 0.000 claims 4
- 125000004432 carbon atom Chemical group C* 0.000 claims 4
- 150000001875 compounds Chemical class 0.000 claims 4
- 238000004020 luminiscence type Methods 0.000 claims 4
- 230000003287 optical effect Effects 0.000 claims 4
- 108090000765 processed proteins & peptides Proteins 0.000 claims 4
- 230000002285 radioactive effect Effects 0.000 claims 4
- 229910000077 silane Inorganic materials 0.000 claims 4
- 125000003545 alkoxy group Chemical group 0.000 claims 3
- 241000894006 Bacteria Species 0.000 claims 2
- 241000233866 Fungi Species 0.000 claims 2
- 101710116435 Outer membrane protein Proteins 0.000 claims 2
- 241000606701 Rickettsia Species 0.000 claims 2
- 239000000589 Siderophore Substances 0.000 claims 2
- 241000700605 Viruses Species 0.000 claims 2
- 150000004676 glycans Chemical class 0.000 claims 2
- 150000002632 lipids Chemical class 0.000 claims 2
- 239000000463 material Substances 0.000 claims 2
- 238000000386 microscopy Methods 0.000 claims 2
- 125000000962 organic group Chemical group 0.000 claims 2
- 229920001282 polysaccharide Polymers 0.000 claims 2
- 239000005017 polysaccharide Substances 0.000 claims 2
- 102000004196 processed proteins & peptides Human genes 0.000 claims 2
- 238000010791 quenching Methods 0.000 claims 2
- 230000000171 quenching effect Effects 0.000 claims 2
- 238000000926 separation method Methods 0.000 claims 2
- 238000005406 washing Methods 0.000 claims 2
- 239000004721 Polyphenylene oxide Substances 0.000 claims 1
- BLRPTPMANUNPDV-UHFFFAOYSA-N Silane Chemical compound [SiH4] BLRPTPMANUNPDV-UHFFFAOYSA-N 0.000 claims 1
- XUIMIQQOPSSXEZ-UHFFFAOYSA-N Silicon Chemical group [Si] XUIMIQQOPSSXEZ-UHFFFAOYSA-N 0.000 claims 1
- 125000000217 alkyl group Chemical group 0.000 claims 1
- 125000003277 amino group Chemical group 0.000 claims 1
- 125000003118 aryl group Chemical group 0.000 claims 1
- 239000007822 coupling agent Substances 0.000 claims 1
- 230000001086 cytosolic effect Effects 0.000 claims 1
- 125000003700 epoxy group Chemical group 0.000 claims 1
- 229910052739 hydrogen Inorganic materials 0.000 claims 1
- 239000001257 hydrogen Substances 0.000 claims 1
- 125000004435 hydrogen atom Chemical class [H]* 0.000 claims 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 claims 1
- 238000011065 in-situ storage Methods 0.000 claims 1
- 230000000813 microbial effect Effects 0.000 claims 1
- 244000005700 microbiome Species 0.000 claims 1
- 229920000768 polyamine Polymers 0.000 claims 1
- 229920000570 polyether Polymers 0.000 claims 1
- 229920000232 polyglycine polymer Polymers 0.000 claims 1
- 231100000654 protein toxin Toxicity 0.000 claims 1
- 108090000623 proteins and genes Proteins 0.000 claims 1
- 102000004169 proteins and genes Human genes 0.000 claims 1
- 229910052710 silicon Inorganic materials 0.000 claims 1
- 125000001424 substituent group Chemical group 0.000 claims 1
- 125000003396 thiol group Chemical group [H]S* 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/999,159 US6780602B2 (en) | 2001-11-01 | 2001-11-01 | Taxonomic identification of pathogenic microorganisms and their toxic proteins |
| US09/999,159 | 2001-11-01 |
Related Child Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2004151018A Division JP2004333503A (ja) | 2001-11-01 | 2004-05-20 | 病原性微生物の分類学的同定及び病原性微生物の毒性タンパク質 |
| JP2004151016A Division JP2004309494A (ja) | 2001-11-01 | 2004-05-20 | 病原性微生物の分類学的同定及び病原性微生物の毒性タンパク質 |
| JP2004151017A Division JP2004317520A (ja) | 2001-11-01 | 2004-05-20 | 病原性微生物の分類学的同定及び病原性微生物の毒性タンパク質 |
| JP2004151015A Division JP2004309493A (ja) | 2001-11-01 | 2004-05-20 | 病原性微生物の分類学的同定及び病原性微生物の毒性タンパク質 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2003185668A JP2003185668A (ja) | 2003-07-03 |
| JP2003185668A5 true JP2003185668A5 (enExample) | 2005-04-07 |
Family
ID=25545977
Family Applications (5)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2002298010A Pending JP2003185668A (ja) | 2001-11-01 | 2002-10-10 | 病原性微生物の分類学的同定及び病原性微生物の毒性タンパク質 |
| JP2004151018A Pending JP2004333503A (ja) | 2001-11-01 | 2004-05-20 | 病原性微生物の分類学的同定及び病原性微生物の毒性タンパク質 |
| JP2004151015A Pending JP2004309493A (ja) | 2001-11-01 | 2004-05-20 | 病原性微生物の分類学的同定及び病原性微生物の毒性タンパク質 |
| JP2004151017A Pending JP2004317520A (ja) | 2001-11-01 | 2004-05-20 | 病原性微生物の分類学的同定及び病原性微生物の毒性タンパク質 |
| JP2004151016A Pending JP2004309494A (ja) | 2001-11-01 | 2004-05-20 | 病原性微生物の分類学的同定及び病原性微生物の毒性タンパク質 |
Family Applications After (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2004151018A Pending JP2004333503A (ja) | 2001-11-01 | 2004-05-20 | 病原性微生物の分類学的同定及び病原性微生物の毒性タンパク質 |
| JP2004151015A Pending JP2004309493A (ja) | 2001-11-01 | 2004-05-20 | 病原性微生物の分類学的同定及び病原性微生物の毒性タンパク質 |
| JP2004151017A Pending JP2004317520A (ja) | 2001-11-01 | 2004-05-20 | 病原性微生物の分類学的同定及び病原性微生物の毒性タンパク質 |
| JP2004151016A Pending JP2004309494A (ja) | 2001-11-01 | 2004-05-20 | 病原性微生物の分類学的同定及び病原性微生物の毒性タンパク質 |
Country Status (7)
| Country | Link |
|---|---|
| US (5) | US6780602B2 (enExample) |
| EP (1) | EP1308520A3 (enExample) |
| JP (5) | JP2003185668A (enExample) |
| CN (1) | CN1417347A (enExample) |
| CA (1) | CA2402588A1 (enExample) |
| HK (1) | HK1054054A1 (enExample) |
| SG (5) | SG152039A1 (enExample) |
Families Citing this family (34)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE10138072A1 (de) * | 2001-08-03 | 2003-02-27 | Fraunhofer Ges Forschung | Verfahren und Vorrichtung zum Bestimmen von Proteinen auf einem Reaktionsträger |
| US6780602B2 (en) * | 2001-11-01 | 2004-08-24 | Microbiosystems, Limited Partnership | Taxonomic identification of pathogenic microorganisms and their toxic proteins |
| CN100362021C (zh) * | 2003-06-06 | 2008-01-16 | 河南大学 | 山药多糖-铁复合物及其制备工艺 |
| WO2005056818A1 (en) * | 2003-12-15 | 2005-06-23 | Rapid Laboratory Microsystems Inc. | Electrochemical assay for the identification of microorganisms |
| JP4686703B2 (ja) * | 2004-10-29 | 2011-05-25 | 国立大学法人 名古屋工業大学 | 細胞固定化材 |
| US20070141597A1 (en) * | 2005-10-25 | 2007-06-21 | Harmon H J | Biomimetic Biodetector of Toxins, Viruses, Bacteria, and Biological Factors |
| JP2008249534A (ja) * | 2007-03-30 | 2008-10-16 | Sanyo Chem Ind Ltd | 免疫測定用担体 |
| EP2197350A2 (en) * | 2007-09-11 | 2010-06-23 | Baxter International Inc. | Infusion therapy sensor system |
| WO2010036829A1 (en) * | 2008-09-24 | 2010-04-01 | Straus Holdings Inc. | Imaging analyzer for testing analytes |
| RU2519650C2 (ru) | 2008-10-31 | 2014-06-20 | Биомерьё, Инк. | Способы разделения, характеристики и(или) идентификации микроорганизмов с помощью масс-спектрометрии |
| CA2741036C (en) * | 2008-10-31 | 2018-01-09 | Biomerieux, Inc. | Methods for separation, characterization, and/or identification of microorganisms using raman spectroscopy |
| US9128058B2 (en) * | 2008-10-31 | 2015-09-08 | Biomerieux, Inc. | Method for separation and characterization of microorganisms using identifier agents |
| US8647835B2 (en) | 2008-10-31 | 2014-02-11 | BIO MéRIEUX, INC. | Methods for separation, characterization and/or identification of microorganisms using spectroscopy |
| EP2364447B1 (en) * | 2008-10-31 | 2019-06-12 | Biomerieux, Inc | Method for the identification of microorganisms |
| CN102203588B (zh) * | 2008-10-31 | 2015-03-18 | 生物梅里埃公司 | 利用光谱分离,表征和/或标识微生物的方法 |
| WO2010062350A1 (en) * | 2008-10-31 | 2010-06-03 | Biomerieux, Inc. | Methods for detection, characterization and/or identification of microorganisms in a sealed container |
| WO2010077304A2 (en) * | 2008-12-16 | 2010-07-08 | Biomerieux, Inc. | Methods for the characterization of microorganisms on solid or semi-solid media |
| WO2011149447A1 (en) | 2010-05-14 | 2011-12-01 | Biomerieux, Inc. | Identification and/or characterization of a microbial agent using taxonomic hierarchical classification |
| US8666673B2 (en) | 2010-05-14 | 2014-03-04 | Biomerieux, Inc | Identification and/or characterization of a microbial agent using taxonomic hierarchical classification |
| CA2803348A1 (en) * | 2010-06-25 | 2012-04-19 | Purdue Research Foundation | Pathogen detection |
| CN104697989B (zh) * | 2013-12-06 | 2017-08-25 | 中国科学院理化技术研究所 | 含Fe3+的复合黏土的制备及其变色法检测水体生物毒性的方法 |
| US9880159B2 (en) | 2014-10-01 | 2018-01-30 | Linda S. Powers | Cartridge-based detection system |
| RU2751241C2 (ru) * | 2015-04-09 | 2021-07-12 | Конинклейке Филипс Н.В. | Способ и устройство для оценки количества микроорганизмов в таксономической единице в образце |
| US9867250B1 (en) | 2015-04-20 | 2018-01-09 | The Arizona Board Of Regents On Behalf Of The University Of Arizona | System having a configurable pico-second pulsed LED driver circuit and photomultiplier tube biasing and gating circuits for real-time, time-resolved transient recording of fluorescence |
| US20180164221A1 (en) * | 2016-12-07 | 2018-06-14 | Progenity Inc. | Gastrointestinal tract detection methods, devices and systems |
| US20210072255A1 (en) | 2016-12-16 | 2021-03-11 | The Brigham And Women's Hospital, Inc. | System and method for protein corona sensor array for early detection of diseases |
| PL4056263T3 (pl) | 2016-12-16 | 2024-12-16 | The Brigham And Women's Hospital, Inc. | System i sposób na matryce sensorowe koron białkowych do wczesnego wykrywania chorób |
| CN119804399A (zh) * | 2018-04-19 | 2025-04-11 | 曙光诊断学公司 | 靶标检测 |
| EP3877400A4 (en) | 2018-11-07 | 2022-09-07 | Seer, Inc. | Compositions, methods and systems for protein corona analysis and uses thereof |
| JP7518852B2 (ja) | 2019-03-26 | 2024-07-18 | シアー, インコーポレイテッド | 生物流体からのタンパク質コロナ分析のための組成物、方法およびシステム、ならびにそれらの使用 |
| GB2606810A (en) | 2019-08-05 | 2022-11-23 | Seer Inc | Systems and methods for sample preparation, data generation, and protein corona analysis |
| CA3190719A1 (en) | 2020-08-25 | 2022-03-03 | Daniel Hornburg | Compositions and methods for assaying proteins and nucleic acids |
| CN114359897A (zh) * | 2020-10-13 | 2022-04-15 | 深圳赛威玛智能科技有限公司 | 病原微生物的智能识别方法、计算机设备及可读存储介质 |
| CN117225491B (zh) * | 2023-11-15 | 2024-01-16 | 拜奥智能科技(山东)有限公司 | 一种可减少氨残留的定氮仪防溅瓶 |
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-
2001
- 2001-11-01 US US09/999,159 patent/US6780602B2/en not_active Expired - Fee Related
-
2002
- 2002-09-10 CA CA002402588A patent/CA2402588A1/en not_active Abandoned
- 2002-09-27 EP EP02021593A patent/EP1308520A3/en not_active Ceased
- 2002-09-27 SG SG200407090-0A patent/SG152039A1/en unknown
- 2002-09-27 SG SG200407092-6A patent/SG145552A1/en unknown
- 2002-09-27 SG SG200407091-8A patent/SG143054A1/en unknown
- 2002-09-27 CN CN02143520A patent/CN1417347A/zh active Pending
- 2002-09-27 SG SG200205915-2A patent/SG130937A1/en unknown
- 2002-09-27 SG SG200406358-2A patent/SG152902A1/en unknown
- 2002-10-10 JP JP2002298010A patent/JP2003185668A/ja active Pending
-
2003
- 2003-09-09 HK HK03106390.0A patent/HK1054054A1/zh unknown
- 2003-11-12 US US10/706,544 patent/US20050026141A1/en not_active Abandoned
- 2003-11-12 US US10/706,542 patent/US20050026140A1/en not_active Abandoned
- 2003-11-12 US US10/706,547 patent/US20040096910A1/en not_active Abandoned
- 2003-11-12 US US10/706,543 patent/US20050032115A1/en not_active Abandoned
-
2004
- 2004-05-20 JP JP2004151018A patent/JP2004333503A/ja active Pending
- 2004-05-20 JP JP2004151015A patent/JP2004309493A/ja active Pending
- 2004-05-20 JP JP2004151017A patent/JP2004317520A/ja active Pending
- 2004-05-20 JP JP2004151016A patent/JP2004309494A/ja active Pending
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