JP2003104858A - Composition for oral cavity - Google Patents

Abstract

PROBLEM TO BE SOLVED: To provide a charcoal powder formulated composition for oral cavity preventing toothbrushes from becoming black after use, homogeneously dispersed with charcoal powder and giving a favorable feeling after use, and to provide a method for producing the charcoal formulated composition for oral cavity of good operability. SOLUTION: This composition for oral cavity contains 0.1-5 mass% of the charcoal powder 0.5-500 μm in mean particle size and 30-80 mass% of a polyhydric alcohol. The method for producing the composition including dispersing the charcoal powder in the polyhydric alcohol and optionally blending the blend with other components (s).

Description

Detailed Description of the Invention

[0001]

TECHNICAL FIELD The present invention relates to an oral composition containing charcoal powder.

[0002]

2. Description of the Related Art Charcoal powder is well known as an adsorbent, and in the field of oral composition, by blending charcoal powder, plaque, tartar and bacteria are adsorbed to cause gingivitis, alveolar pyorrhea. It is proposed to be useful for the prevention and treatment of malaria and the prevention of bad breath (Japanese Patent Publication No. 8-26862, JP-A-10-9).
5721, Japanese Patent Laid-Open No. 2000-128751,
See Japanese Patent Laid-Open No. 2000-143467). However, after using a dentifrice containing such a charcoal powder, even if the toothbrush is washed, the charcoal powder remains and the toothbrush becomes black. In addition, the charcoal powder is expected to have an effect as an abrasive. Since charcoal powder has a mild polishing effect on the tooth surface, an oral composition containing charcoal powder having a good feeling in use is required. Furthermore, there is a problem that the charcoal powder is not easily dispersed in the manufacturing process of the oral composition containing the charcoal powder, and the charcoal powder-containing oral composition is required to have a uniform dispersion of the charcoal powder.

[0003]

SUMMARY OF THE INVENTION It is an object of the present invention to provide a charcoal powder-containing oral composition in which the toothbrush after use does not turn black. It is another object of the present invention to provide a charcoal-powder-containing oral composition in which charcoal powder is uniformly dispersed and has a good feeling in use. Another object of the present invention is to provide a method for producing an oral composition containing charcoal powder.

[0004]

Means for Solving the Problems As a result of intensive studies to achieve the above object, the inventors of the present invention blended an oral composition with a carbon powder having a predetermined particle size in combination with a specific base. By doing so, it was found that it is possible to suppress the adhesion of the charcoal powder to the toothbrush, and obtain a composition for oral cavity with good uniformity of dispersion of the charcoal powder, and completed the present invention. . It was also found that the combination with a specific base material facilitates the uniform dispersion of the charcoal powder in the manufacturing process and improves workability. Therefore, according to the present invention, carbon powder having an average particle size in the range of 0.5 to 500 μm can be used as a powder.
1 to 5 mass% and polyhydric alcohol 30 to 80 mass%
It is an oral composition characterized by containing. In a preferred embodiment of the present invention, the average particle size is 0.5 to 200.
Within the range of μm, 90% by mass or more of all particles is 150μ
There is the above-mentioned oral composition characterized by containing 0.1 to 5 mass% of charcoal powder having a particle size of m or less. The present invention is further directed to the above-mentioned composition for oral cavity, which contains 0.5 to 5.0% by mass of an anionic surfactant. The present invention is further directed to the above oral composition containing at least one selected from the group consisting of L-menthol, peppermint oil, spearmint oil and eucalyptus oil. The present invention also provides a polyhydric alcohol in which charcoal powder having an average particle size in the range of 0.5 to 500 μm is dispersed, and the resulting mixture is optionally mixed with other components for oral cavity use. It relates to a method for producing a composition.

[0005]

BEST MODE FOR CARRYING OUT THE INVENTION The oral composition as used herein refers to toothpastes such as toothpaste, liquid toothpaste and moisturizing toothpaste, creams, ointments, patches, and mouth fresheners. , Mouthwash, chewing gum or mouthwash.

The charcoal powder used in the present invention is black charcoal, and is specifically at least one selected from charcoal, activated charcoal, bamboo charcoal, bone charcoal and the like. Carbide, activated charcoal, bamboo charcoal, bone charcoal, etc. have excellent adsorptive power, and also have a polishing effect because they have an appropriate altitude for tooth enamel.
It can be said that it is a very suitable material as a dentifrice. It has various effects such as adsorbing or polishing foreign substances such as bacteria in the mouth and food waste, making the mouth alkaline with natural minerals contained in charcoal, and preventing acidification of the mouth due to waste products generated by bacteria. Since these carbides are natural materials, they are human-friendly and have no water pollution, so they can be used as an environment-friendly dentifrice.

The charcoal powder used has an average particle size of 0.
Those having an average particle diameter of 5 to 500 μm are suitable, those having an average particle diameter of 0.5 to 200 μm are preferably used, and more preferably 0.5 to 100 μm.
Those in the range of m are used. Further, among the charcoal powders having the above-mentioned average particle diameter, charcoal powders in which 90% by mass or more of all particles have a particle diameter of 150 μm or less can be preferably used. When the particle size is in such a range, the adsorption ability of the charcoal powder is appropriate, the adsorption to the toothbrush can be suppressed, the dispersibility of the charcoal powder in the composition is good, and the feeling of use is good. Charcoal powder having an average particle size as described above is commercially available. Also, a sieve can be used to adjust the particle size. In the oral composition of the present invention, the content of the above-mentioned charcoal powder is appropriately 0.1 to 5.0 mass% based on the total mass of the oral composition, and preferably 0.1.
~ 3.0 mass%, more preferably 0.1-1.0 mass%
Is the range.

The oral composition of the present invention further contains 30 to 80% by mass of a polyhydric alcohol. In the composition for oral cavity of the present invention, good dispersibility of the charcoal powder is achieved by mixing the charcoal powder having the above-mentioned specific particle size range and the polyhydric alcohol in a predetermined amount. Examples of the polyhydric alcohol used in the present invention include glycerin, propylene glycol, polyethylene glycol and the like, and sugar alcohols such as sorbitol, xylitol, maltitol, erythritol, mannitol and lactitol, and at least one of them is used. can do. Above all, it is preferable to mix one or more of glycerin, which is a trihydric alcohol, and sorbitol and xylitol, which are sugar alcohols, in combination. The compounding amount of the polyhydric alcohol in the oral composition of the present invention is 30 to 80% by mass based on the total mass of the oral composition.
Is suitable, preferably 35 to 70% by mass, more preferably 40 to 60% by mass.

The method for producing the oral composition of the present invention is not particularly limited, and it can be produced according to a conventional method. As a preferred production method, charcoal powder is mixed and dispersed in at least a part or all of the polyhydric alcohol blended in the oral composition, and the mixture is optionally mixed with other components, for example, the remaining polyhydric alcohol, and It is suitable to mix with any of the additives as described. For example, in the case of toothpaste, after mixing the charcoal powder and the polyhydric alcohol to disperse the charcoal powder in the polyhydric alcohol, other ingredients such as a base, a wetting agent,
It can be manufactured by kneading with a binder, water and the like, then adding an oil-soluble component such as a fragrance, and then stirring in vacuum. By such a production method, the charcoal powder can be easily and uniformly dispersed in the oral composition.

As an embodiment of the oral composition of the present invention,
It is preferable to add an anionic surfactant. Known anionic surfactants are used. For example, a water-soluble salt of a higher alkyl sulfate having 8 to 20 carbon atoms such as sodium lauryl sulfate is particularly effectively used, and a water-soluble alkylbenzene sulfonate such as sodium dodecylbenzenesulfonate is used. Amino acid type surfactants such as organic salts, sodium lauryl sulfoacetate, sodium lauroyl sarcosine and the like can be mentioned. The blending amount of the anionic surfactant is appropriately 0.5 to 5% by mass, preferably 1 to 3% by mass based on the total mass of the oral composition. If the blending amount exceeds 5% by mass, the flavor of the oral composition and the effect of suppressing oral bacteria may be adversely affected.

The oral composition of the present invention preferably contains at least one cooling agent selected from the group consisting of L-menthol, peppermint oil, spearmint oil and eucalyptus oil. The content of these cooling agents in the oral composition is 0.0 based on the total mass of the oral composition.
1 to 5 mass% is suitable, and 0.1 to 1 mass% is preferable.

The oral composition of the present invention may be further blended with additives usually used in oral compositions. Specific examples are given below. <Base> As the base, silicic acid anhydride, silica gel, precipitable silica, fumed silica, hydrous silicic acid, aluminosilicate, silica-based abrasives of zirconosilicate, dibasic calcium phosphate, dibasic calcium phosphate anhydrous, Calcium pyrophosphate, aluminum hydroxide, alumina, light calcium carbonate, heavy calcium carbonate, magnesium carbonate, magnesium triphosphate, zeolite, zirconium silicate, calcium triphosphate, hydroxyapatite, fluoroapatite, calcium-deficient apatite, calcium tetraphosphate , 8-calcium phosphate, synthetic resin-based abrasives, and the like. These can be used alone or in combination of two or more. The blending amount of these is preferably 1 to 60% by mass, and more preferably 5 to 40% by mass with respect to the entire composition.

<Wetting agent> One kind or two or more kinds of dipropylene glycol, propylene glycol, 1,3-butylene glycol and the like can be used. <Binder> Carrageenan (ι, λ, κ), alginic acid,
Alginates such as sodium alginate, propylene glycol alginate, calcium-containing sodium alginate, potassium alginate, calcium alginate, ammonium alginate and derivatives thereof, xanthan gum, guar gum, gelatin, agar, sodium carboxymethyl cellulose, hydroxyethyl cellulose, sodium polyacrylate, polyvinyl. Pyrrolidone, glucomannan, etc. are mentioned, and these can be used 1 type or in combination of 2 or more types.

<Foaming agent> N-acyl amino acid salts such as coconut oil fatty acid sodium monoglycerin sulfonate, sodium α-olefin sulfonate and N-acyl glutamate,
2-alkyl-N-carboxymethyl-N-hydroxyethyl imidazolinium betaine, maltitol fatty acid ester, sucrose fatty acid ester, polyglycerin fatty acid ester, fatty acid diethanolamide, polyoxyethylene sorbitan monostearate, polyoxyethylene hardened castor Oil, polyoxyethylene fatty acid ester and the like can be mentioned, and of these, one kind or two or more kinds can be used in combination. <PH adjuster> Citric acid and its salts, phosphoric acid and its salts, malic acid and its salts, aspartic acid and its salts,
Examples include succinic acid and its salts, glucuronic acid and its salts, fumaric acid and its salts, glutamic acid and its salts, adipic acid and its salts, hydrochloric acid, hydrofluoric acid, alkali metal hydroxides, etc. Alternatively, two or more kinds can be used in combination.

<Sweetener> Sodium saccharin, aspartame, stevioside, stevia extract, paramethoxycinnamic aldehyde, neohesperidyl dihydrochalcone, perillartin and the like. <Preservative> Parabens such as methylparaben, ethylparaben, propylparaben and butylparaben, sodium benzoate, phenoxyethanol, alkyldiaminoethylglycine hydrochloride and the like.

<Perfume ingredient> One kind or two or more kinds in combination of anethole, menthone, cineol, limonene, carvone, methyl salicylate, ethyl butyrate, eugenol, thymol, cinnamic aldehyde, trans-2-hexenal, etc. Can be used. These components may be blended individually, but essential oils containing them may be blended. In addition to the above-mentioned fragrance components, fragrance components such as aliphatic alcohols and esters thereof, terpene-based hydrocarbons, phenol ethers, aldehydes, ketones, lactones, and essential oils may be added within a range that does not impair the effects of the present invention. The blending amount of the above fragrance is preferably 0.02 to 2 mass% with respect to the entire composition.

<Active ingredient> Lysozyme chloride, monofluorophosphate, sodium fluoride, potassium fluoride,
Sodium monofluorophosphate, polyethylene glycol, polyvinylpyrrolidone, zeolite, hinokitiol, ascorbic acid, triclosan, isopropylmethylphenol, tocopherol acetate, ε-aminocaproic acid, tranexamic acid, aluminum hydroxyl allantoin, aluminum lactate, dihydrocholesterol, glycyrrhetinic acid, glycyrrhizin. One or more of acid salts, copper chlorophyllin salt, sodium chloride, guaizulene sulfonate, dextranase, pyridoxine hydrochloride, medicinal hydroxyapatite and the like can be blended.

<Others> Dyes such as Blue No. 1, pigments such as titanium oxide, antioxidants such as dibutylhydroxytoluene, chelating agents such as edetate, tea extract, tea dry distillation liquid, propolis extract, sodium glutamate and the like. Agents, etc. <Solvent> Water, ethanol

The oral composition such as the toothpaste of the present invention can be used by filling it in an aluminum tube, a laminate tube, a glass vapor deposition tube, a transparent tube, a plastic tube, a plastic bottle, an aerosol container or the like.

[0020]

EFFECTS OF THE INVENTION According to the oral composition containing the charcoal powder of the present invention, it is possible to prevent the charcoal powder from adhering to the toothbrush and prevent the toothbrush from becoming black. The oral composition containing the charcoal powder of the present invention also has the charcoal powder uniformly dispersed therein. Moreover, the oral composition of the present invention has a good feeling in use. Furthermore, according to the method for producing an oral composition of the present invention, it is possible to easily achieve uniform dispersion of the charcoal powder in the oral composition with good workability, and to obtain a preferable charcoal powder-blended oral composition. it can.

[0021]

[Examples] Toothpaste compositions of Examples 1 to 3 and Comparative Examples 1 to 3 were prepared with the compositions (unit: mass%) shown in Table 1 below. Preparation procedure: Disperse medicinal charcoal (activated carbon) having an average particle diameter of about 68 μm (90% by mass or more of all particles have a particle diameter of 150 μm or less) in a polyhydric alcohol, and then disperse the dispersion liquid with other components. Mixed. (Observation of Adsorption of Charcoal Powder on Toothbrush) 1.5 g of each of the obtained toothpaste compositions was placed on a commercially available toothbrush, and the oral cavity was brushed for 3 minutes while mixing the horizontal method and the vertical method. After that, apply the brushed toothbrush to tap water,
Rinse for about 30 seconds. The adsorption of the charcoal powder on the toothbrush was visually observed. The evaluation is as follows. ○: There is no remaining. △: Somewhat remains (black ones can be confirmed). ×: A lot remains (the black one can be clearly seen). (Observation of dispersibility of charcoal powder in composition for oral cavity) Each of the obtained toothpaste compositions is filled in a tube and taken out on a glass plate by about 1 to 3 cm. The toothpaste composition on the glass plate was thinly spread, and it was visually confirmed whether or not the carbon powder was uniformly dispersed. The evaluation is as follows. ○: Good dispersibility Δ: The dispersibility is slightly poor. X: Poor dispersibility. The results are also shown in Table 1.

[0022]

[Table 1] ^* Comparative Example 3 did not have sufficient shape retention as a toothpaste.

A toothpaste was prepared by mixing the following basic formulation with medicinal charcoal (activated charcoal) having different average particle diameters, and the charcoal powder was adsorbed on the toothbrush after use and the feeling of use was evaluated. [Basic formulation] (total amount is 100% by mass) Calcium carbonate 30.0 (% by mass) Charcoal powder (average particle size is as shown in Table 2) 3.0 Silica anhydride 7.0 Glycerin 30.0 Sorbit liquid (70%) 5.0 Xylitol 5.0 Sodium carboxymethyl cellulose 1.0 Sodium lauryl sulfate 2.0 Sodium saccharin 0.05 Paraben 0.1 1-Menthol 0.05 Perfume 1.0 Purified water Appropriate amount

1.5 g of each of these toothpastes is put on a commercially available toothbrush, and while mixing the horizontal method and the vertical method, 3
Brushed the mouth for a minute. Then, the brushed toothbrush was immersed in tap water and rinsed for about 30 seconds. The adsorption of the charcoal powder on the toothbrush was visually observed. The feeling of use of charcoal during polishing (dispersibility in the oral cavity and polishing comfort) was also evaluated. The results are shown in Table 2. Evaluation of adsorption of charcoal powder on toothbrush ○: No residue remains. △: Somewhat remains (black ones can be confirmed). ×: A lot remains (the black one can be clearly seen). Evaluation of feeling of use ◯: Good dispersibility in the oral cavity and moderate polishing feeling. Fair: dispersibility is good, but polishing feeling is not satisfactory. X: Poor dispersibility and poor polishing comfort. Here, "polishing comfort" refers to the feel of the charcoal powder on the tooth surface, and a moderate feel without any roughness is evaluated. If the particle size is small, there is no substantial feeling, while if it is coarse, graininess occurs.

[0025]

[Table 2]

<Evaluation of dispersibility of charcoal powder in manufacturing dentifrice according to difference in method of adding charcoal powder> In preparation of dentifrice, charcoal powder is powder, wetting agent, and binder in the following modes a to d. And water were added to the mixed intermediate preparation, and the mixture was kneaded with a mixer. Then, a fragrance (oil-soluble component) was added and the mixture was vacuum-stirred to obtain a dentifrice. a: Disperse charcoal powder in glycerin and then add to the intermediate preparation. b: Disperse charcoal powder in sorbit solution (70%) and then add to intermediate formulation. c: The charcoal powder is dispersed in water and then added into the intermediate preparation. d: Add charcoal powder directly to the intermediate formulation. The used charcoal powder is medicinal charcoal (activated carbon) having an average particle size of about 68 μm, and 90% by mass or more of all particles have a particle size of 150 μm or less. Glycerin, sorbit or water and charcoal powder The compounding ratio (mass ratio) was changed.
The content of the charcoal powder and the polyhydric alcohol in the dentifrice composition was 0.1 to 5 mass% and the polyhydric alcohol was 30 to 80 mass%, respectively.

Evaluation of dispersibility The obtained dentifrice is spread thinly on a plastic white plate,
The dispersibility of the charcoal powder was evaluated as follows. The results are shown in Table 3 below. ○: Good dispersibility △: Partially poor dispersibility ×: Poor dispersibility

[0028]

[Table 3]

Various toothpastes were prepared according to the following formulations (unit: mass%). The medicinal charcoal (activated carbon) used had an average particle size of about 68 μm and 90% by mass or more of all particles had a particle size of 150 μm or less. Example 4 Cetylpyridinium chloride 0.05 Medicinal charcoal 0.5 Heavy carbonic acid carbonate 20.0 Silica anhydride 5.0 Concentrated glycerin 10.0 Sorbit solution (70%) 30.0 Sodium carboxymethylcellulose 1.0 Sodium lauryl sulfate 1.5 Saccharin sodium 0.1 Sodium benzoate 0.1 Tocopherol acetate 0.1 Perfume 1.0 Purified water Suitable amount Total 100.0

Example 5 Chlorhexidine hydrochloride 0.001 Medicinal charcoal 3.0 Aluminum hydroxide 35.0 Silicic anhydride 5.0 Concentrated glycerin 35.0 Carrageenan 1.0 Sodium lauryl sulfate 0.5 Xylitol 3.0 Stevia extract 0.05 Sodium benzoate 0.1 β-glycyrrhetinic acid 0.05 Fragrance 1.0 Purified water Suitable amount 100.0 in total

Example 6 Decalinium chloride 0.01 Medicinal charcoal 1.0 Ground calcium carbonate 25.0 Silicic anhydride 7.0 Propylene glycol 15.0 Sorbit solution (70%) 25.0 Xanthan gum 1.0 Sodium lauryl sulfate 1.0 Saccharin sodium 0.03 Paraben 0.1 β-glycyrrhetinic acid 0.05 Tocopherol acetate 0.1 Fragrance 1.0 Purified water Suitable amount 100.0 in total

Example 7 Chlorhexidine gluconate 0.05 Medicinal charcoal 5.0 Calcium pyrophosphate 15.0 Silicic anhydride 7.0 Concentrated glycerin 40.0 Carrageenan 0.5 Carboxymethyl cellulose sodium 0.8 Sodium lauryl sulfate 1.5 Stevia extract 0.1 Paraben 0.1 Lysozyme chloride 0.4 ε-aminocaproic acid 0.1 Fragrance 1.0 Purified water Suitable amount 100.0 in total

Example 8 Chlorhexidine hydrochloride 0.02 Cetylpyridinium chloride 0.01 Medicinal charcoal 3.0 Silicic anhydride 10.0 Concentrated glycerin 15.0 Sorbit solution (70%) 25.0 Carrageenan 1.0 Sodium lauryl sulfate 0.8 Maltitol 5.0 Stevia extract 0.05 Paraben 0.1 Tranexamic acid 0.1 Fragrance 1.0 Purified water Suitable amount 100.0 in total

   ─────────────────────────────────────────────────── ─── Continued front page    (72) Inventor Shinji Sugiyama             5-13-16 Tobio, Atsugi City, Kanagawa Prefecture (72) Inventor Hiroyoshi Otani             1326-9 Zushimachi, Machida-shi, Tokyo F-term (reference) 4C083 AB131 AB132 AB172 AB292                       AB322 AC111 AC122 AC132                       AC482 AC622 AC782 AC862                       AD272 AD352 AD532 CC41                       EE31

Claims (5)

[Claims] 1. A composition for oral cavity containing 0.1 to 5% by mass of charcoal powder having an average particle size of 0.5 to 500 μm and 30 to 80% by mass of a polyhydric alcohol. . 2. A carbon powder having an average particle size of 0.5 to 200 μm and 90% by mass or more of all particles having a particle size of 150 μm or less is contained in an amount of 0.1 to 5% by mass. The oral composition according to claim 1. 3. The oral composition according to claim 1, which contains 0.5 to 5.0% by mass of an anionic surfactant. 4. The oral composition according to claim 1, which contains at least one selected from the group consisting of L-menthol, peppermint oil, spearmint oil, and eucalyptus oil. 5. A polyhydric alcohol having an average particle size of 0.5 to
A method for producing an oral composition, wherein charcoal powder in a range of 500 μm is dispersed, and the resulting mixture is optionally mixed with other components.