JP2007070256A - Dentifrice composition - Google Patents

Abstract

<P>PROBLEM TO BE SOLVED: To provide a dentifrice composition having excellent tightening feeling and massaging effects of gums, and hardly having salty taste. <P>SOLUTION: The dentifrice composition contains (A) 10-50 mass% erythritol having ≥355 μm and <855 μm particle diameters, (B) 10-40 mass% water and (C) 0.6-3 mass% binder. <P>COPYRIGHT: (C)2007,JPO&INPIT

Description

  The present invention relates to a dentifrice composition containing erythritol.

Periodontal disease is one of the two major diseases in the oral cavity along with caries. In particular, alveolar pyorrhea is a serious problem in today's aging society. Therefore, the prevention and treatment has a very important meaning in oral hygiene, and a toothpaste containing sodium chloride as a medicinal agent for the purpose is commercially available. The effect of this salt is said to improve circulation in the gingival region by absorbing tissue fluid in the inflamed gingiva. Furthermore, it has also been reported that by adding granular salt that has a large particle size not dissolved in the toothpaste composition, saltiness is reduced and a gum massage effect is imparted (see Patent Document 1). However, since salt is added at a high concentration for the purpose of enhancing the effect, saltiness remains and some children do not like its use.
Japanese Patent Laid-Open No. 10-152424

  An object of the present invention is to provide a toothpaste composition which is excellent in gum tightening feeling and massage effect and has no saltiness.

The present invention includes the following components (A), (B) and (C):
(A) 10 to 50% by mass of erythritol having a particle size of 355 μm or more and less than 855 μm
(B) Water 10-40% by mass
(C) Binder 0.6-3 mass%
A toothpaste composition containing
The present invention also includes the following components (A), (B) and (C):
(A) 10 to 50% by mass of erythritol having a particle size of 355 μm or more and less than 855 μm
(B) Water 10-40% by mass
(C) Binder 0.6-3 mass%
Is a toothpaste composition.

  The toothpaste composition of the present invention is excellent in gum tightness and massage effect, and has no salty taste. Moreover, it can be stored stably for a long time.

The dentifrice composition of the present invention is characterized by containing erythritol (component (A)) having a particle size of 355 μm or more and less than 855 μm. As the toothpaste composition of the present invention, it is preferable to use a erythritol obtained by fermenting glucose and then recrystallized to adjust the particle size by pulverization as necessary.
A roller mill, a hammer mill, a high-speed pulverizer, a pulverizer, etc. are generally used to pulverize erythritol, but a high-speed pulverizer and hammer mill that are easy to adjust the particle size and excellent in production efficiency. Is preferred.
The structure of erythritol includes three isomers of L-erythritol, D-erythritol, and meso-erythritol, and the present invention may have any of these structures. As crystalline erythritol, commercially available products such as those manufactured by Nikken Chemical Co., Ltd., Mitsubishi Chemical Foods Co., Ltd., and Celestor are available.

In the toothpaste composition of the present invention, the content of erythritol having a particle size of 355 μm or more and less than 855 μm is 10 to 50% by mass, more preferably 15 to 45% by mass, and still more preferably, from the viewpoint of a massage effect on the gums. It is 20-40 mass%, Most preferably, it is 25-35 mass%.
For this reason, the blending amount of erythritol having a particle size of 355 μm or more and less than 855 μm is 10 to 50% by mass, more preferably 15 to 45% by mass, still more preferably 20 to 40% by mass, and particularly preferably 25 to 35% by mass. It is.

  The particle diameter of erythritol is preferably 355 μm or more and less than 855 μm from the viewpoint of a massage effect on the gums. More preferably, they are 400 micrometers or more and less than 750 micrometers, More preferably, they are 450 micrometers or more and less than 700 micrometers. When the particle diameter of erythritol is less than 355 μm, the feeling of massage is not sufficient, and the particle diameter of erythritol is preferably less than 855 μm from the viewpoint of spreading to the whole oral cavity.

The erythritol particle size is measured as follows.
Sieve: JIS standard sieve φ75mm
Opening: From the top, a receiver is placed under a sieve having openings of 855 μm and 355 μm.
Shaker: Micro type electromagnetic vibrator M-2 type (Tsutsui Rikenki Co., Ltd.)
Method: Place 15 g of sample on a 855 μm sieve and classify with an electromagnetic vibrator for 5 minutes.
The erythritol existing on the sieve having an opening of 355 μm is erythritol having a particle size of 355 or more and less than 855 μm.

  In the toothpaste composition of the present invention, the content of water (component (B)) is preferably 10% by mass or more from the viewpoint of storage stability of the dentifrice, and preferably 40% by mass or less from the viewpoint of preventing dissolution of erythritol particles. . More preferably, it is 12-35 mass%, More preferably, it is 15-30 mass%, Most preferably, it is 15-25 mass%.

The binder (component (C)) used in the present invention is not particularly limited. For example, sodium alginate, sodium carboxymethylcellulose, carrageenan, xanthan gum, sodium polyacrylate, hydroxyethylcellulose, hydroxypropylcellulose, pectin, tragacanth gum, Use one or more water-soluble polymers selected from gum arabic, guar gum, karaya gum, locust bean gum, gellan gum, tamarind gum, psyllium seed gum, polyvinyl alcohol, sodium chondroitin sulfate and methoxyethylene maleic anhydride copolymer It is preferable to do this.
In the dentifrice composition of the present invention, the content of the binder is from 0.6 to 3% by mass, more preferably from 0.7 to 2% by mass, and even more preferably from the viewpoint of storage stability. 8 to 1.2% by mass.

  In the toothpaste composition of the present invention, in addition to the above components, for example, foaming agent, foaming aid, abrasive, wetting agent, sweetener, preservative, enzyme, pH adjuster, bactericidal agent, medicinal component, pigment, dye, A fragrance | flavor etc. can be contained suitably.

  As abrasives, silica-based abrasives such as precipitated silica, silica gel, aluminosilicate, zirconosilicate; dicalcium phosphate dihydrate and anhydrous, calcium pyrophosphate, calcium carbonate, alumina, aluminum hydroxide, acetic acid Magnesium, tribasic magnesium phosphate, zeolite, synthetic resin-based abrasive and the like are preferably used.

As the wetting agent, glycerin, sorbitol, propylene glycol, polyethylene glycol, xylitol, maltite, lactit, trehalose and the like are preferably used.
Furthermore, examples of the sweetener include saccharin sodium, aspartame, thaumatin, acesulfame potassium, stevioside, stevia extract, paramethoxycinnamic aldehyde, neohesperidyl dihydrochalcone, and perilartin.

  As a fragrance, 1-menthol, carvone, anethole, eugenol, limonene, peppermint oil, spearmint oil, ocimen, n-amyl alcohol, citronellol, α-terpineol, methyl salicylate, methyl acetate, citronole acetate, cineol, linalool, Examples include ethyl linalool, crocodile, thymol, lemon oil, orange oil, sage oil, rosemary oil, cinnamon oil, pimento oil, perilla oil, clove oil, and eucalyptus oil.

  As other various active ingredients, water-soluble phosphate compounds such as potassium salt and sodium salt of orthophosphoric acid; allantochlorohydroxyaluminum, azulene, glycyrrhetinic acid, epidihydrocholesterin, α-bisabolol, glycyrrhizic acid and the like Anti-inflammatory agents such as salts; phenolic compounds such as hinokitiol; antiplasmin agents such as tranexamic acid and epsilon aminocaproic acid; vitamin Es of dl-tocopherol acetate; copper compounds such as copper chlorophyllin sodium and copper gluconate; sodium chloride; Salts such as potassium nitrate; bactericides such as quaternary ammonium compounds such as triclosan, cetylpyridinium chloride, benzethonium chloride, chlorhexidine salts, trichlorocarbanilide; dextranase, mutanase, amylase, chloride Enzymes such as lysozyme; extracts such as sugarcane, duck, clove, rosemary, hornon, safflower; aluminum lactate, strontium chloride, berberine, hydroxamic acid and its derivatives, sodium tripolyphosphate, zeolite, polyvinylpyrrolidone, dihydrocholesterol, citric acid Zinc etc. are mentioned.

  In the toothpaste composition of the present invention, it is desirable that erythritol is dispersed in a powder state from the viewpoint of obtaining a higher refreshing feeling. For this purpose, erythritol is preferably added as a powder to the final production process. By using such a production method, erythritol can be present in a powder state in the toothpaste composition without being substantially dissolved in water. Specifically, for example, after measuring the prescribed amount of each component such as purified water, wetting agent, binder, flavoring agent, preservative, abrasive, foaming agent, sweetener, and medicinal component, it is according to certain production conditions. The toothpaste composition of the present invention can be produced by mixing and fully swelling the binder, and further adding a polishing agent, a foaming agent, a flavoring agent, and powdered erythritol and defoaming and mixing.

  The toothpaste composition of the present invention has a viscosity at 25 ° C. (helicus type viscometer, rotor C, 2.5 r / min, 1 minute) of 1500 to 5000 dPa · s, further 2000 to 4500 dPa · s, particularly 2500 to 4000 dPa · s. Is preferred.

<Preparation of toothpaste composition>
According to the composition shown in Table 1, toothpaste compositions of Examples 1-4 and Comparative Examples 1-3 were prepared. Erythritol was added last.

(1) Evaluation of storage stability Each toothpaste composition shown in Table 1 was packed in a toothpaste tube for storage, and stored at 5 ° C, room temperature, and 40 ° C for 3 months. Thereafter, the tube was opened and whether or not the liquid component was separated from the toothpaste composition was evaluated according to the following criteria.
<Evaluation criteria for storage stability>
◎: No liquid separation is observed ○: Liquid separation is slightly observed ×: Liquid separation is clearly observed

(2) Evaluation of massage effect on gums After 10 subjects (5 men and 5 women) took 1 g of each brushing composition on a toothbrush and brushed freely for about 2 minutes, the brushing composition of Comparative Example 1 Based on the above, the massage effect on the gums was evaluated according to the following criteria.
<Evaluation criteria for massage effect on gums>
◎: The massage effect is clearly stronger than the standard toothpaste ○: The massage effect is equivalent to the standard toothpaste ×: The massage effect is weaker than the standard toothpaste

(3) Taste evaluation Ten test subjects (5 men, 5 women) took 1 g of each toothbrushing composition on a toothbrush and brushed freely for about 2 minutes. Then, based on the toothpaste composition of Comparative Example 1, The taste was evaluated according to the following criteria.
<Taste Evaluation Criteria>
◎: Does not feel salty ○: Feels slightly salty ×: Feels salty clearly

  As shown in Table 1, since the toothpaste compositions of Examples 1 to 4 contain a large amount of erythritol having a particle size of 355 to 855 μm, the toothpaste has excellent massage effect on gums and further contains granular salt. The result was that it tasted better than the composition. Moreover, in the toothbrushing composition of Examples 2-4, since it contained more erythritol whose particle diameter is 355-855 micrometers, it was the result of being further excellent in the massage effect to a gum. Moreover, since it contained 15-30 mass% of moisture and 0.6-3 mass% of binder, it was excellent in long-term storage stability.

  On the other hand, the toothpaste composition of Comparative Example 1 contained a large amount of granular salt having a particle diameter of 700 to 1400 μm, and thus had a massage effect on the gums, but it felt that saltiness was clearly felt. Further, the toothpaste composition of Comparative Example 2 does not have a sufficient massage effect on the gums, and the toothpaste composition of Comparative Example 3 has a low water content and a small amount of binder, so that the storage stability is high. The result was bad.

Claims (3)

The following components (A), (B) and (C):
(A) 10 to 50% by mass of erythritol having a particle size of 355 μm or more and less than 855 μm
(B) Water 10-40% by mass
(C) Binder 0.6-3 mass%
A toothpaste composition comprising: The following components (A), (B) and (C):
(A) 10 to 50% by mass of erythritol having a particle size of 355 μm or more and less than 855 μm
(B) Water 10-40% by mass
(C) Binder 0.6-3 mass%
A toothpaste composition.   (C) is sodium alginate, sodium carboxymethyl cellulose, carrageenan, xanthan gum, sodium polyacrylate, hydroxyethyl cellulose, hydroxypropyl cellulose, pectin, tragacanth gum, gum arabic, guar gum, caraya gum, locust bean gum, gellan gum, tamarind gum, psyllium seed The dentifrice composition according to claim 1 or 2, which is one or more binders selected from the group consisting of gum, polyvinyl alcohol, sodium chondroitin sulfate and a methoxyethylene maleic anhydride copolymer.