JP4658747B2 - Toothpaste composition - Google Patents

Description

  The present invention relates to a dentifrice composition containing erythritol.

  In general, the purpose of brushing teeth is to clean the mouth and obtain a refreshing feeling. A fragrance ingredient represented by menthol, which is usually included in a toothpaste composition, is indispensable for imparting a refreshing feeling, but in recent years, there has been a tendency to increase the number of oily meals and meals using spices. Therefore, a toothpaste composition having a higher refreshing feeling is desired.

  As a means to improve the refreshing feeling, there are methods such as increasing the blending amount of perfume ingredients or adding a solvent component such as ethanol. However, increasing the blending amount of these ingredients increases the irritation in the oral cavity. Moreover, since foaming is suppressed, there arises a problem that the feeling of use when polished is impaired.

  Therefore, a toothpaste composition that obtains a higher refreshing feeling without increasing the blending amount of a fragrance component or a solvent such as ethanol is desired.

Patent Document 1 discloses a toothpaste composition having an excellent refreshing feeling, which contains a component that causes an endothermic hydration reaction such as erythritol and has a water content of 10% by mass or less. However, although a refreshing sensation was obtained, a clear cooling sensation was not obtained in the oral cavity.
JP 2000-191383 A

  An object of the present invention is to provide a toothpaste composition containing erythritol, which has a higher refreshing sensation and cooling sensation and is excellent in tooth cleaning effect.

  The present inventor first studied a method for enhancing the refreshing feeling and cooling feeling when brushing teeth, and as a result, contains erythritol having a specific particle size, and further adjusts its content and the amount of water in the composition. And it discovered that a refreshing feeling and a cool feeling could be improved. However, since a large amount of erythritol is required, it was necessary to reduce raw materials such as abrasives, wetting agents, binders, surfactants, etc. to make dentifrices, and the tooth cleaning effect was not sufficient. . Therefore, as a result of further examination to efficiently remove tooth stains even with a small amount of raw material, it was found that an excellent tooth cleaning effect can be obtained if a specific abrasive is used in combination.

That is, the present invention includes the following components (A) to (C):
(A) Erythritol having a particle diameter of less than 355 μm, 25 to 60% by mass
(B) Water 10-40% by mass
(C) 5-20 mass% of the following abrasive powders
(C1) The average particle diameter is 1 to 10 μm, and the RDA value is 150 to 300.
(C2) The average particle size is 5 to 20 μm, and the RDA value is 50 to 150.
A toothpaste composition containing
The present invention also includes the following components (A) to (C):
(A) 30-60% by mass of erythritol having a particle size of less than 355 μm
(B) Water 10-40% by mass
(C) 5-20 mass% of the following abrasive powders
(C1) The average particle diameter is 1 to 10 μm, and the RDA value is 150 to 300.
(C2) The average particle size is 5 to 20 μm, and the RDA value is 50 to 150.
Is a toothpaste composition.

  By applying the toothpaste composition according to the present invention to the oral cavity, a higher refreshing feeling can be obtained, and furthermore, the tooth cleaning effect is also excellent.

The dentifrice composition of the present invention is characterized by containing erythritol (component (A)) having a particle size of less than 355 μm. Normally available erythritol is crystalline erythritol obtained by recrystallizing after fermenting glucose, and its particle size is larger than that of the product of the present invention. Therefore, it is preferable to use what obtained the erythritol grind | pulverized and adjusted the particle diameter for the toothbrushing composition of this invention.
A roller mill, hammer mill, high-speed pulverizer, pulverizer, etc. are generally used to pulverize erythritol, but a high-speed pulverizer and hammer mill that are easy to adjust the particle size and excellent in production efficiency. Is preferred.
The structure of erythritol includes three isomers of L-erythritol, D-erythritol, and meso-erythritol, and the present invention may have any of these structures. As crystalline erythritol, commercially available products such as those manufactured by Nikken Chemical Co., Ltd., Mitsubishi Chemical Foods Co., Ltd., and Celestor are available.

  The particle diameter of erythritol is less than 355 μm because it can provide a cool feeling and a cool feeling, but is preferably 3 μm or more and less than 355 μm. From the viewpoint that the cooling sensation persists in the mouth, it is preferably 45 μm or more and less than 355 μm, more preferably 45 μm or more and less than 300 μm, and particularly preferably 45 μm or more and less than 250 μm.

The erythritol particle size is measured as follows.
Sieve: JIS standard sieve φ75mm
Opening: From the upper stage, a receiver is provided under a sieve having openings of 500 μm, 355 μm, 250 μm, 180 μm, 125 μm, 90 μm and 45 μm, respectively.
Shaker: Micro type electromagnetic vibrator M-2 type (Tsutsui Rikenki Co., Ltd.)
Method: Place 15 g of sample on 500 μm sieve and classify with electromagnetic vibrator for 5 minutes. The total amount of erythritol present on a sieve having openings of 250 μm, 180 μm, 125 μm, 90 μm and 45 μm is defined as erythritol having a particle size of 45 μm or more and less than 355 μm.
The particle size distribution of less than 45 μm can be measured with a dry laser distribution diffraction particle size distribution measuring apparatus.

In the toothpaste composition of the present invention, the content of erythritol having a particle size of less than 355 μm is 25 to 60% by mass, more preferably 25 to 55% by mass, and still more preferably from the viewpoint of obtaining a high refreshing feeling. 30-50% by mass.
For this reason, the compounding quantity of the erythritol whose particle diameter is less than 355 micrometers is 30-60 mass%, More preferably, it is 30-55 mass%, More preferably, it is 35-50 mass%.

  In the toothpaste composition of the present invention, the content of water (component (B)) is 10 to 40% by mass, more preferably 12 to 35% by mass from the viewpoint of obtaining storage stability and a higher refreshing feeling and cooling feeling. More preferably, it is 15-30 mass%, Most preferably, it is 18-25 mass%.

  The abrasive powder (component (C)) includes silica-based abrasives such as hydrous silica, anhydrous silica, silica gel, aluminosilicate, zirconosilicate, dicalcium phosphate dihydrate and anhydrous, pyro Calcium phosphate, calcium carbonate, alumina, aluminum hydroxide, magnesium acetate, tribasic magnesium phosphate, zeolite, etc. are used, especially hydrous silica, anhydrous silica, calcium hydrogen phosphate dihydrate from the viewpoint of cleaning effect and safety. , Anhydrous calcium hydrogen phosphate, alumina, aluminum hydroxide, calcium carbonate, and zeolite are preferably used. In the toothpaste composition of the present invention, the content of these abrasive powders is 5 to 20% by mass, more preferably 8 to 18% by mass, and even more preferably 10 to 15% by mass, from the viewpoint of obtaining a sufficient cleaning effect. %.

  As the abrasive powder, two kinds of abrasive powders (C1) and abrasive powders (C2) having different physical properties are used in combination. By using these two in combination, an excellent tooth cleaning effect can be obtained with a small amount of powder. The abrasive powder (C1) has an average particle size of 1 to 10 μm, more preferably 2 to 8 μm, still more preferably 3 to 6 μm, and an RDA value of 150 to 300, more preferably 180 to 250. It is. The abrasive powder (C2) has an average particle size of 5 to 20 μm, more preferably 6 to 18 μm, still more preferably 8 to 15 μm, and an RDA value of 50 to 150, more preferably 80. ~ 120. Here, RDA (Radioactive Dentin Abrasion: Radial Dentin Abrasion Value) is a scale indicating the abrasiveness of tooth brushing on dentin, and is an RDA test method (Hefferen, Journal of Dental Research 1976, No. 7, 8 p.563). -573).

  As the abrasive powder, it is preferable to use two kinds of abrasive powders (C1) and abrasive powders (C2) having different physical properties, and these two kinds of abrasive powders are selected from the same kind. There is no need, and it can be freely selected and used from the above-mentioned abrasive powders. Furthermore, the compounding ratio of the abrasive powder (C1) and the abrasive powder (C2) is 50:50 to 5:95, more preferably 40:60 to 10:90.

  In the toothpaste composition of the present invention, in addition to the above components, for example, a binder, a foaming agent, a foaming aid, a wetting agent, a sweetener, a preservative, an enzyme, a pH adjuster, a bactericidal agent, a medicinal component, a pigment, A pigment | dye, a fragrance | flavor, etc. can be contained suitably.

  Binders are sodium alginate, sodium carboxymethylcellulose, carrageenan, xanthan gum, sodium polyacrylate, hydroxyethylcellulose, hydroxypropylcellulose, pectin, tragacanth gum, gum arabic, guar gum, caraya gum, locust bean gum, gellan gum, tamarind gum, psyllium seed It is preferable to use one or more water-soluble polymers composed of gum, polyvinyl alcohol, sodium chondroitin sulfate, and methoxyethylene maleic anhydride copolymer. In the toothpaste composition, the content of the binder is preferably 0.6 to 2% by mass, more preferably 0.7 to 1.5% by mass, and still more preferably, from the viewpoint of the stability of the toothpaste composition. Is 0.8 to 1.2% by mass.

  As the wetting agent, glycerin, sorbitol, propylene glycol, polyethylene glycol, xylitol, maltite, lactit, trehalose and the like are preferably used. It is preferable to use polyethylene glycol from the viewpoint of supplementing the tooth cleaning effect. Polyethylene glycol has the effect of dissolving tobacco dust, so it is effective against tooth stains caused by smoking. When used in combination with abrasive powder, it can further enhance the cleaning effect of teeth. It becomes. Here, the molecular weight of polyethylene glycol is 200 to 6000, more preferably 200 to 3000, still more preferably 200 to 1000, and the content is 1 to 15% by mass, more preferably 3 to 12. It is 5 mass%, More preferably, it is 5-10 mass%.

  Furthermore, examples of the sweetening agent include saccharin sodium, aspartame, thaumatin, acesulfame potassium, stevioside, stevia extract, paramethoxycinnamic aldehyde, neohesperidyl dihydrochalcone, and perilartin.

  As a fragrance, 1-menthol, carvone, anethole, eugenol, limonene, peppermint oil, spearmint oil, ocimen, n-amyl alcohol, citronellol, α-terpineol, methyl salicylate, methyl acetate, citronole acetate, cineol, linalool, Examples include ethyl linalool, crocodile, thymol, lemon oil, orange oil, sage oil, rosemary oil, cinnamon oil, pimento oil, perilla oil, clove oil, and eucalyptus oil.

  Other various active ingredients include water-soluble phosphate compounds such as potassium phosphate and sodium salt of orthophosphoric acid, allantochlorohydroxyaluminum, hinokitiol, lysozyme chloride, glycyrrhizic acid and its salts, sodium chloride, tranexamic acid, epsilon. Aminocaproic acid, dl-tocopherol acetate, azulene, glycyrrhetinic acid, copper chlorophyllin sodium, copper compounds such as copper gluconate, aluminum lactate, strontium chloride, potassium nitrate, berberine, hydroxamic acid and its derivatives, sodium tripolyphosphate, zeolite, dextranase , Mutanase, amylase, methoxyethylene, maleic anhydride copolymer, polyvinylpyrrolidone, epidihydrocholesterin, dihydrocholesterol, zinc citrate, Float, cork tree bark, clove, rosemary, scutellaria, an extract of such safflower, alpha-bisabolol, chlorhexidine salts, triclosan, cetylpyridinium chloride, benzethonium chloride, trichlorocarbanilide, and the like.

  In the toothpaste composition of the present invention, it is desirable that erythritol is dispersed in a powder state from the viewpoint of obtaining a higher refreshing feeling. For this purpose, erythritol is preferably added as a powder to the final production process. By using such a production method, erythritol can be present in a powder state in the toothpaste composition without being substantially dissolved in water. Specifically, for example, after measuring the prescribed amount of each component such as purified water, wetting agent, binder, flavoring agent, preservative, abrasive, foaming agent, sweetener, and medicinal component, it is according to certain production conditions. The toothpaste composition of the present invention can be produced by mixing and fully swelling the binder, and further adding a polishing agent, a foaming agent, a flavoring agent, and powdered erythritol and defoaming and mixing.

[Preparation of toothpaste composition]
According to the composition shown in Table 1, toothpaste compositions of Examples 1 to 4 and Comparative Examples 1 to 4 were prepared.
Erythritol was added last.

(1) Evaluation of cool feeling and cool feeling Ten subjects (5 men, 5 women) took 1 g of each brushing composition on a toothbrush and brushed freely for about 2 minutes. The strength of the refreshing feeling after rinsing was evaluated according to the following criteria. In addition, the result of the determination shown in Table 1 shows the highest evaluation among 10 people.
<Evaluation criteria for coolness>
◎: Strong feeling in mouth ○: Refreshing feeling in mouth is slightly strong ×: Feeling in mouth is weak <Evaluation criteria for cool feeling>
◎: The mouth feels clear and the cool feeling persists. ○: The mouth feels a little cool. ×: The mouth feels cool.

(2) Evaluation of tooth model dirt removal power A commercially available video tape with the magnetic powder side facing up is fixed to a brush friction and wear tester (HEIDON-14) with a plastic plate. Using a round cut toothbrush with a normal bristle hardness and a flocking length of 2 cm, each toothbrushing composition shown in Table 1 was squeezed to the entire toothbrush, and the load was 300 g, the brushing distance was 3 cm, and the speed was 120 rpm. The magnetic powder surface was stroked 250 times. In addition, the toothbrush was added to the toothbrush again every 50 strokes, and the same test was done. Thereafter, the model dirt removal rate was calculated from the following formula, and the model dirt removal power was evaluated according to the following criteria.

Model dirt removal rate (%) = (peeling area of magnetic powder / area brushed out by toothbrush) × 100
◎: Model dirt removal rate is 70% or more ○: Model dirt removal rate is 50% to less than 70% ×: Model dirt removal rate is less than 50%

(3) Evaluation of harmfulness to teeth The RDA values of the toothpaste compositions shown in Table 1 were measured according to the RDA test method, and the harmfulness to teeth was evaluated according to the following criteria.
<Evaluation criteria for harmfulness to teeth>
◎: RDA value is less than 150 ○: RDA value is 150 or more and less than 250 ×: RDA value is 250 or more

(4) Evaluation of tooth cleaning effect The tooth cleaning effect was evaluated according to the following criteria based on the results of the model dirt removal power and the harmful effect on the teeth.
<Evaluation criteria for tooth cleaning effect>
◎: When both evaluation results are ◎ ○: When either one is ○ and the other is ◎ ×: Either one is × or both are ×

  As shown in Table 1, the toothpaste compositions of Examples 1 to 4 contain a large amount of erythritol having a particle size of less than 355 μm, and further contain powders having different abrasive properties. The result was excellent. Furthermore, since the toothpaste compositions of Examples 2 to 4 contained more erythritol having a particle size of less than 355 μm, the refreshing feeling was further improved. In addition, none of the toothpaste compositions showed liquid separation in the storage stability test at room temperature for 3 months.

On the other hand, in the toothpaste composition of Comparative Example 1, the content of erythritol having a particle size of less than 355 μm was small, and therefore the refreshing feeling was weak. Moreover, since the toothbrushing composition of Comparative Example 2 contains only a highly abrasive powder, the result is that the harmfulness to the teeth is bad and the cleaning effect of the teeth is insufficient. Since the composition contains only a low-abrasive powder, the result was that the tooth model dirt removal ability was low and the tooth cleaning effect was insufficient. Further, the toothpaste composition of Comparative Example 4 contains a large amount of erythritol having a particle size of 355 μm or more, so that the refreshing feeling and cooling feeling are weak, and furthermore, the content of the abrasive powder is small, and therefore the tooth model. The result was that the dirt removing power was low and the cleaning effect of the teeth was insufficient.

Claims (5)

The following components (A) to (C):
(A) Erythritol having a particle diameter of less than 355 μm, 25 to 60% by mass
(B) water from 12 to 40 wt%
(C) 5-20 mass% of the following abrasive powders
(C1) The average particle diameter is 1 to 10 μm, and the RDA value is 150 to 300.
(C2) The average particle size is 5 to 20 μm, and the RDA value is 50 to 150.
A toothpaste composition comprising erythritol dispersed in powder form in the composition. The following components (A) to (C):
(A) 30-60% by mass of erythritol having a particle size of less than 355 μm
(B) water from 12 to 40 wt%
(C) 5-20 mass% of the following abrasive powders
(C1) The average particle diameter is 1 to 10 μm, and the RDA value is 150 to 300.
(C2) The average particle size is 5 to 20 μm, and the RDA value is 50 to 150.
A toothpaste composition in which erythritol is dispersed in a powder state in the composition.   The dentifrice composition according to claim 1 or 2, wherein the compounding ratio of the abrasive powder of component (C) and (C1) and (C2) is 50:50 to 5:95.   The abrasive powder of component (C) is one selected from hydrous silica, anhydrous silica, calcium hydrogen phosphate dihydrate, calcium hydrogen phosphate anhydrate, alumina, aluminum hydroxide, calcium carbonate and zeolite or The dentifrice composition of Claim 1 or 2 which is 2 or more types. Furthermore, the dentifrice composition of any one of Claims 1-4 which contains 0.6-2 mass% of binders.