JP2008013528A - Dentifrice composition - Google Patents

Abstract

<P>PROBLEM TO BE SOLVED: To obtain a dentifrice composition having excellent storage stability, an excellent firm feeling and refreshing feeling. <P>SOLUTION: The dentifrice composition comprises (A) 15-60 mass% of erythritol having a particle diameter of ≥45μm and <355μm, (B) 3-35 mass% of salt having a particle diameter of ≥500μm and <1,000μm, (C) 0.3-10 mass% of a binder and (D) 10-30 mass% of water and has the mass ratio of salt to erythritol of ≤1. <P>COPYRIGHT: (C)2008,JPO&INPIT

Description

  The present invention relates to a toothpaste composition excellent in the feeling of tightness and cleanliness of gums.

  The risk of periodontal disease increases with aging, and it is said that failure to perform routine self-care and regular checkups will result in loss of teeth and, as a result, overall health. To date, a number of periodontal disease preventing dentifrices have been developed as means of self-care for periodontal diseases. For example, various medicinal ingredients such as bactericides, anti-inflammatory agents, sodium chloride, protease inhibitors are blended. In order to continue to use a dentifrice containing these medicinal ingredients, it is important to feel the effect after brushing at the same time as the effect. In particular, the feeling of tightness and cleanliness of the gums in the sense of effectiveness is a synergistic feeling that reminds us of the feeling that the dentifrice directly acts on the gums and encourages continued use. As a means for improving the general feeling of tightness, there is a method of adding salts such as salt and baking soda to a dentifrice. However, when the compounding amount of salt and the like is increased, there is a problem that the taste is drastically reduced due to the taste of the salt and the feeling of use is greatly impaired although the feeling of crushing is improved. On the other hand, as a means for improving the feeling of cleanliness, there is a method of increasing the amount of surfactant or abrasive in the dentifrice, but if it is simply increased, it becomes bitter or powdery and the use feeling is significantly impaired. . Therefore, a dentifrice composition that continuously improves the intention to use by realizing a higher crushing feeling and a clean feeling without increasing the blending amount of salts, surfactant and abrasive is desired.

Patent Document 1 reports a method for producing salt granules, wherein the salt particles are granulated and / or coated with a water-insoluble substance. However, although there is a description about the improvement of the feeling of tightness after polishing, there is no description about the clean feeling.
Patent Document 2 discloses a toothpaste composition in which a salt such as baking soda is added in addition to salt to suppress a crushing effect and salty taste. However, since baking soda has a unique salty taste, the user tends to be limited.
Furthermore, Patent Document 3 describes a dentifrice that contains erythritol having a specific particle size and has a refreshing feeling. The feeling of use is a cool feeling based on the cool feeling, and there is no description regarding the clean feeling. The refreshing feeling is a refreshing feeling mainly obtained by increasing the amount of flavored menthol, and is different from the clean feeling that the whole mouth feels clean.
JP-A-6-11626 JP-A-7-206650 JP-A-2005-281306

  An object of the present invention is to provide a toothpaste composition that is excellent in storage stability and has a higher feeling of tightness and cleanliness.

  Therefore, the present inventor has studied crispness, cleanliness and storage stability by blending erythritol and salt in a dentifrice, and controls the particle size of erythritol and the particle size of salt, and the blending ratio thereof is set. It has been found that by making it within a certain range, the storage stability is excellent, and a high feeling of tightness and cleanliness can be obtained.

That is, the present invention includes the following components (A) to (D):
(A) Erythritol having a particle size of 45 μm or more and less than 355 μm 15 to 60% by mass
(B) 3 to 35% by mass of sodium chloride having a particle size of 500 μm or more and less than 1000 μm
(C) Binder 0.3 to 10% by mass
(D) Water 10-30 mass%
And a dentifrice composition having a mass ratio of sodium chloride to erythritol of 1 or less.
The present invention also includes the following components (A) to (D):
(A) Erythritol having a particle diameter of 45 μm or more and less than 355 μm 20 to 60% by mass
(B) Sodium chloride having a particle diameter of 500 μm or more and less than 1000 μm, 5 to 35 mass%
(C) Binder 0.3 to 10% by mass
(D) Water 10-30 mass%
And a dentifrice composition having a mass ratio of sodium chloride to erythritol of 1 or less.
Further, the present invention provides the above-mentioned dentifrice composition characterized by adding erythritol having a particle size of 45 μm or more and less than 355 μm and sodium chloride having a particle size of 500 μm or more and less than 1000 μm after mixing the binder and water. A method is provided.

  The toothpaste composition of the present invention is excellent in storage stability by adding granular sodium chloride and granular erythritol, and provides a high feeling of gumming and cleanliness.

  The toothpaste composition of the present invention is characterized by containing erythritol having a particle size of 45 μm or more and less than 355 μm and sodium chloride having a particle size of 500 μm or more and less than 1000 μm.

  As the structure of erythritol, there are three isomers of L-erythritol, D-erythritol, and meso-erythritol, and the present invention may have any of these structures.

  In general, erythritol is obtained by fermenting glucose and then recrystallizing crystalline erythritol into a granular form using a roller mill, hammer mill, high-speed pulverizer, pulverizer, or the like. As the crystalline erythritol, for example, those commercially available from Nikken Chemical Co., Ltd., Mitsubishi Chemical Foods Co., Ltd., Selestar, etc. can be used. In order to obtain the particle size distribution of the present invention, pulverization with a high-speed pulverizer or hammer mill, which is easy to adjust the particle size and excellent in production efficiency, is preferable.

In the toothpaste composition of the present invention, the erythritol content is 15 to 60% by mass, more preferably 20 to 40% by mass, and still more preferably 25 to 35% by mass from the viewpoint of clean feeling and tight feeling.
The particle size of erythritol is 45 μm or more and less than 355 μm, but is preferably 53 μm or more and less than 300 μm, and more preferably 75 μm or more and less than 250 μm, from the viewpoint that a clean feeling continues in the oral cavity. When the particle diameter of erythritol is less than 45 μm, the particle diameter is small, so it dissolves quickly in the mouth, and the clean feeling does not last long. On the other hand, those exceeding 355 μm are difficult to dissolve in the oral cavity and thus do not exhibit a tight feeling.

The erythritol particle size is measured as follows.
Sieve: JIS standard sieve φ75mm
Aperture: 500 μm, 355 μm, 250 μm, 180 μm, 125 from the top
The receiver is located under a sieve with openings of μm, 90 μm and 45 μm.
Shaker: Micro type electromagnetic vibrator M-2 type (Tsutsui Rikenki Co., Ltd.)
Method: Place 15 g of sample on a 500 μm sieve and classify by shaking for 5 minutes with an electromagnetic vibrator. The total amount of erythritol present on a sieve having openings of 250 μm, 180 μm, 125 μm, 90 μm and 45 μm is defined as erythritol having a particle size of 45 μm or more and less than 355 μm.

  In the present invention, the erythritol having the above particle size blended in the toothpaste composition needs to be contained in a granular form. Since erythritol is a substance that is soluble in water, it is preferable to contain erythritol having a solubility higher than the solubility in the toothpaste composition in order to be included in the toothpaste composition throughout the shelf life of the product. It is preferable to blend an excess amount of erythritol in a granular form with respect to the water content. The amount of erythritol contained in the toothpaste composition is 15 to 60% by mass, but considering the solubility of erythritol, at least a certain amount or more of erythritol having a particle size enough to maintain a granular shape without dissolving. Further, the blending amount is preferably 20 to 60% by mass, and particularly preferably 20 to 50% by mass.

  The particle diameter of the salt used in the present invention is 500 μm or more and less than 1000 μm from the viewpoint that a clean feeling and a tight feeling continue in the oral cavity for a long time. When the particle diameter of the salt is less than 500 μm, the particle diameter is small, so it dissolves quickly in the mouth, and the feeling of tightness does not last long. On the other hand, when the thickness exceeds 1000 μm, there is a feeling of massage, but salt feels that the teeth are sandwiched between the teeth, and the intention to continue use decreases.

In addition, the particle diameter of salt is measured as follows.
Sieve: JIS standard sieve φ75mm
Opening: From the upper stage, a receiver is provided under a sieve having openings of 1000 μm, 850 μm, 710 μm, 600 μm, and 500 μm, respectively.
Shaker: Micro type electromagnetic vibrator M-2 type (Tsutsui Rikenki Co., Ltd.)
Method: Place 15 g of sample on a 1000 μm sieve and classify with an electromagnetic vibrator for 5 minutes. The total amount of sodium chloride present on a sieve having openings of 850 μm, 710 μm, 600 μm, and 500 μm is defined as sodium chloride having a particle diameter of 500 μm or more and less than 1000 μm.

  The salt used in the present invention may be produced by any production method such as one made from seawater and one made from rock salt. In the past, when it was made from seawater, it was mainly made from sun-salt made using the characteristics of the Japanese climate, but now it is made by a production method such as an ion exchange membrane method that concentrates and produces seawater. The content of the salt is from 3 to 35% by mass, and more preferably from 10 to 20% by mass, from the viewpoints of cleanliness and tightness.

  In the present invention, the amount of erythritol (A) and sodium chloride (B) needs to be such that the mass ratio of sodium chloride to erythritol in the toothpaste composition is 1 or less. On the contrary, when the amount of salt added to the granular erythritol increases (B / A> 1), the clean feeling and the tight feeling are remarkably lowered. In order to exert the effect of the present invention, the blending ratio of salt to erythritol (B / A) is particularly preferably 0.6 or less, and more preferably at least 0.3 or more.

  As the binder (component (C)) used in the present invention, generally usable binders for dentifrices can be used, such as sodium alginate, sodium carboxymethylcellulose, carrageenan, xanthan gum, sodium polyacrylate. , Hydroxyethylcellulose, hydroxypropylcellulose, pectin, tragacanth gum, gum arabic, guar gum, karaya gum, locust bean gum, gellan gum, tamarind gum, psyllium seed gum, polyvinyl alcohol, sodium chondroitin sulfate and methoxyethylene maleic anhydride copolymer One type or two or more types of water-soluble polymers may be mentioned. In particular, since sodium chloride is blended, it is preferable to include sodium carboxymethylcellulose. Carboxymethyl cellulose preferably has a high degree of etherification from the viewpoint of stability, preferably has a degree of etherification of 0.8 or more, particularly preferably 0.8 to 1.5, and more preferably 0.8 to 1.3. In the toothpaste composition of the present invention, the content of the binder is 0.3 to 10% by mass from the viewpoint of storage stability, more preferably 0.5 to 8% by mass, and further preferably 1 to 5% by mass. %.

  In the toothpaste composition of the present invention, the content of water (component (D)) is 10 to 30% by mass, and more preferably 10 to 20% by mass from the viewpoint of obtaining storage stability, a high degree of tightness and a clean feeling. It is. When the amount is less than 10% by mass, the binder is not sufficiently dissolved and the stability is lowered. On the other hand, when the amount exceeds 30% by mass, it is difficult to maintain a clean feeling.

  In the toothpaste composition of the present invention, in addition to the above components, for example, foaming agent, foaming aid, abrasive, wetting agent, sweetener, preservative, enzyme, pH adjuster, bactericidal agent, medicinal component, pigment, dye, A fragrance | flavor etc. can be contained suitably.

  Foaming agents include anionic, nonionic, cationic, and amphoteric surfactants. Examples of the anionic surfactant include sodium lauryl sulfate, an amino acid surfactant, and a sulfosuccinic acid surfactant. Nonionic surfactants include polyglycerol fatty acid esters, sucrose fatty acid esters, fatty acid alkanolamide surfactants such as coconut oil fatty acid diethanolamide, polyoxyethylene hydrogenated castor oil, polyoxyethylene higher alcohol ether, polyoxyethylene And ethylene fatty acid esters, alkyl glucosides, and polyoxyethylene polyoxypropylene copolymers. These foaming agents may be used alone or in combination of two or more, and the content thereof is usually preferably 0.01 to 40% by mass, particularly 0%, based on the entire dentifrice composition. 0.5 to 20% by mass is preferable. In particular, from the viewpoint of foaming properties, it is preferable to include sodium alkyl sulfate, preferably using an alkyl group having 8 to 18 carbon atoms, particularly 10 to 16 carbon atoms, and further 12 to 14 carbon atoms in an arbitrary ratio. Can do.

  As abrasives, silica-based abrasives such as precipitated silica, silica gel, aluminosilicate, zirconosilicate; dicalcium phosphate dihydrate and anhydrous, calcium pyrophosphate, calcium carbonate, alumina, aluminum hydroxide, acetic acid Magnesium, tribasic magnesium phosphate, zeolite, synthetic resin-based abrasive and the like are preferably used. The content of the abrasive is preferably 5 to 20% by mass, more preferably 8 to 18% by mass, and particularly preferably 10 to 15% by mass in the dentifrice composition.

  As the wetting agent, glycerin, sorbitol, propylene glycol, polyethylene glycol, xylitol, maltite, lactit, trehalose and the like are preferably used.

  Furthermore, examples of the sweetener include saccharin sodium, aspartame, thaumatin, acesulfame potassium, stevioside, stevia extract, paramethoxycinnamic aldehyde, neohesperidyl dihydrochalcone, and perilartin.

  As a fragrance, 1-menthol, carvone, anethole, eugenol, limonene, peppermint oil, spearmint oil, ocimen, n-amyl alcohol, citronellol, α-terpineol, methyl salicylate, methyl acetate, citronole acetate, cineol, linalool, Examples include ethyl linalool, crocodile, thymol, lemon oil, orange oil, sage oil, rosemary oil, cinnamon oil, pimento oil, perilla oil, clove oil, and eucalyptus oil.

  As other various active ingredients, water-soluble phosphate compounds such as potassium salt and sodium salt of orthophosphoric acid; allantochlorohydroxyaluminum, azulene, glycyrrhetinic acid, epidihydrocholesterin, α-bisabolol, glycyrrhizic acid and the like Anti-inflammatory agents such as salts; phenolic compounds such as hinokitiol; antiplasmin agents such as tranexamic acid and epsilon aminocaproic acid; vitamin Es of dl-tocopherol acetate; copper compounds such as copper chlorophyllin sodium and copper gluconate; sodium chloride; Salts such as potassium nitrate; bactericides such as quaternary ammonium compounds such as triclosan, cetylpyridinium chloride, benzethonium chloride, chlorhexidine salts, trichlorocarbanilide; dextranase, mutanase, amylase, chloride Enzymes such as lysozyme; extracts such as sugarcane, duck, clove, rosemary, hornon, safflower; aluminum lactate, strontium chloride, berberine, hydroxamic acid and its derivatives, sodium tripolyphosphate, zeolite, polyvinylpyrrolidone, dihydrocholesterol, citric acid Zinc etc. are mentioned.

  In the toothpaste composition of the present invention, it is desirable that erythritol and sodium chloride are dispersed in a granular state. For this purpose, it is preferable to add erythritol and sodium chloride to the final step of production after mixing the binder and water. By using such a production method, erythritol and sodium chloride can be present in powder form in the dentifrice composition without being substantially dissolved in water. Specifically, for example, after prescription measurement of each component such as purified water, wetting agent, binder, flavoring agent, preservative, abrasive, foaming agent, sweetener, and medicinal component, first, it is caustic with water. Mixing agent to fully swell the binder, and then add other ingredients such as abrasives, foaming agents, flavoring agents, etc., then add erythritol and salt, defoaming and mixing, toothpaste of the present invention A composition can be produced.

<Preparation of toothpaste composition>
According to the composition shown in Table 1, Examples A to D and Comparative Examples E to J were prepared. Erythritol and sodium chloride were added last.

(1) Evaluation of storage stability The toothpaste composition shown in Table 1 was packed in a toothpaste tube for storage and stored at 5 ° C, room temperature, and 50 ° C for 1 month. Thereafter, the tube was opened, and whether or not the liquid component was separated from the toothpaste was evaluated according to the following criteria.

<Evaluation criteria for storage stability>
A: No separation of liquid is observed.
○: Slight separation of liquid is observed.
X: Liquid separation is clearly observed.

(2) Evaluation of feeling of tightness 5 expert panelists took 1g of a toothbrushing composition on a toothbrush with a blind and brushed freely for about 2 minutes. It was evaluated according to the evaluation criteria. The average value of the evaluation was used as the evaluation of the toothpaste.

<Evaluation criteria for feeling of tightness>
Compared to standard toothpaste F, this toothpaste composition
3: Feels that my gums have been pulled.
2: Feels that the gums are slightly pulled.
1: I can't say either.

(3) Evaluation of cleanliness 5 expert panelists took 1g of a toothbrushing composition on a toothbrush with a blind and brushed freely for about 2 minutes. It was evaluated according to the evaluation criteria. The average value of the evaluation was used as the evaluation of the toothpaste.

<Evaluation criteria for cleanliness>
Compared to standard toothpaste F, this toothpaste composition
3: The mouth feels clean.
2: The mouth feels a bit clean.
1: I can't say either.

(4) Evaluation of intention to continue using 10 evaluation panelists (5 men, 5 women) took 1 g of the toothbrushing composition on the toothbrush with the blinds, brushed freely for about 2 minutes, and then want to use it continuously. The number of people who wanted to use it was used as an evaluation standard for intention to continue using it.

  The toothpaste composition (AD) of the present invention, in which erythritol and salt having a certain particle size are blended, and the blending ratio is 1 or less, is excellent in storage stability, excellent in tightness and cleanliness, Therefore, it was a thing with a high intention of continuous use. On the other hand, Comparative Example E in which the compounding ratio of sodium chloride relative to erythritol was greater than 1 was not sufficiently clean and had a low intention to continue use. Comparative Example F containing no erythritol, toothpaste composition (GI) containing erythritol or sodium chloride having different particle diameters were not sufficient in both tightness and cleanliness, and the transition to continuous use was also low. In Comparative Example J having a small amount of water, sufficient storage stability could not be obtained.

Claims (6)

Next components (A) to (D)
(A) Erythritol having a particle size of 45 μm or more and less than 355 μm 15 to 60% by mass
(B) 3 to 35% by mass of sodium chloride having a particle size of 500 μm or more and less than 1000 μm
(C) Binder 0.3 to 10% by mass
(D) Water 10-30 mass%
And a dentifrice composition having a mass ratio of sodium chloride to erythritol of 1 or less. Next components (A) to (D)
(A) Erythritol having a particle diameter of 45 μm or more and less than 355 μm 20 to 60% by mass
(B) 5 to 35% by mass of sodium chloride having a particle size of 500 μm or more and less than 1000 μm
(C) Binder 0.3 to 10% by mass
(D) Water 10-30 mass%
A toothpaste composition wherein the mass ratio of sodium chloride to erythritol is 1 or less.   The dentifrice composition according to claim 1 or 2, wherein erythritol is present in a granular form in the dentifrice composition.   The dentifrice composition according to any one of claims 1 to 3, wherein the salt is present in a granular form in the dentifrice composition.   Component (C) is sodium alginate, sodium carboxymethyl cellulose, carrageenan, xanthan gum, sodium polyacrylate, hydroxyethyl cellulose, hydroxypropyl cellulose, pectin, tragacanth gum, gum arabic, guar gum, caraya gum, locust bean gum, gellan gum, tamarind gum, psyllium The dentifrice composition according to any one of claims 1 to 4, which is one or more binders selected from the group consisting of seed gum, polyvinyl alcohol, sodium chondroitin sulfate and a methoxyethylene maleic anhydride copolymer. .   The toothpaste according to claim 1, wherein erythritol having a particle size of 45 μm or more and less than 355 μm and sodium chloride having a particle size of 500 μm or more and less than 1000 μm are added after mixing the binder and water. A method for producing the composition.