JP2003095884A - Hair grower material using elaeagnus glabra thunb. - Google Patents

Abstract

PROBLEM TO BE SOLVED: To provide a safe hair grower material having good hair growing effect and causing no allergic reaction on the scalp. SOLUTION: This hair grower material is obtained by diluting an ingredient with water derived from trace amounts of a ferrous or ferric salt, wherein the ingredient is obtained by extraction of or boiling down the trunks, leaves or fruits of Elaeagnus glabra Thunb. with an alcohol.

Description

Detailed Description of the Invention

[0001]

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a hair-growth raw material, and an object thereof is to provide a safe hair-growth raw material having an excellent hair-growth effect and which does not cause an allergic reaction to the scalp. To provide.

[0002]

2. Description of the Related Art Conventionally, many hair cosmetics, pharmaceuticals, and quasi-drugs used for the purpose of hair growth and hair nourishment have been created. Expands blood vessels, promotes blood circulation, and further stimulates the papilla to promote hair production, hair-growth ingredients, ingredients that give a refreshing feeling, ingredients that have a bactericidal action, ingredients that prevent dandruff and itchiness, etc. There is. Specifically, as a hair growth ingredient, female hormone, vitamin E, pantothenic acid, capsicum tincture,
Ginseng tincture, assembly extract, cepharanthine, photosensitizer, etc., have ethanol as a component that gives a refreshing feeling and have a bactericidal action, as anti-dandruff components, resorcin, salicylic acid, zinc pyridione, etc. There are a large number of products in which the above are mixed.

[0003]

However, the conventional hair-growth compositions as described above do not provide a sufficient hair-growth effect, and sometimes give an unfavorable stimulus to the scalp. Therefore, there is a demand for the creation of a safe hair-growth agent raw material which has an excellent hair-growth effect and which does not give unfavorable irritation to the scalp. Then, as a hair-growth agent raw material having such an excellent hair-growth effect and having a high safety for the scalp that is derived from a natural product, as described in JP-A No. 11-286414, a heron (Clerodendron trichotomum Thunb.). , Nothopanax scutellarium Mer.,
Kukuoki (Aleurites moluccanaWilld.), Kayupte (Melaleuca leucadendra L.), Thrush (Elaeagnus)
glabra Thunb.), as well as these extracts and pressed oils have been developed and found to have excellent hair growth effects.

However, in the hair restorer raw material comprising the above plant extract and compressed oil, the extract is applied to the scalp as a 99% ethanol solution. Therefore, the present condition is that the ability to penetrate the scalp is weak and the function originally possessed by the extract cannot be fully exerted. Therefore, the present invention is, among the raw materials for hair-growth agents derived from the above-mentioned tense products,
It has been found that Turgus has a remarkable hair-growing effect, and by diluting it with an extremely small amount of water induced by divalent and trivalent iron salts, it has high penetrating power to the scalp and the extract's original function is sufficient. The present invention is intended to provide a hair-growth agent raw material that uses turdus that is capable of exhibiting excellent effects.

[0005]

Means for Solving the Problems That is, a hair-growth agent raw material using the turmeric of this invention is
aeagnus glabra Thunb.) stem, leaf, or fruit components obtained by alcohol extraction or boiling, and obtained by diluting this with water induced by an ultratrace amount of divalent and trivalent iron salts. It is what

[0006] In the hair-growth agent raw material using turmeric of the present invention, water derived from the above-mentioned ultra-trace amount of divalent and trivalent iron salt has a pH of 7
It is also characterized by neutral water before and after.

In the hair-growth agent raw material using turmeric of the present invention, the alcohol extract is a monohydric alcohol, a polyhydric alcohol or a derivative thereof, a ketone, an ester, an ether, a petroleum ether, an aliphatic hydrocarbon or a halide thereof, It is also characterized in that the extract is an anhydrous or water-containing organic solvent containing at least one selected from aromatic hydrocarbons.

[0008]

BEST MODE FOR CARRYING OUT THE INVENTION As the hair-growth agent raw material according to the present invention, Thrush (Elaeagnus glabra Thunb.) Is used.

In the present invention, all the above-ground and below-ground parts of the above plant can be used.
Each part such as a fruit part, a flower part, a leaf part and a stem part may be used alone or as a mixture. Further, both the dried state and the non-dried state are preferably used.

The form of use of the above plant is not particularly limited, but it is desirable to use an extract or boiled juice of the above plant as a hair restorer raw material. Of course, it is also possible to use a soft extract or a dry extract obtained by concentrating or drying the above extract.

When the above extract is used as a hair restorer raw material, the solvent to be used is not particularly limited, but anhydrous or hydrous organic solvents, especially monohydric alcohols, polyhydric alcohols or derivatives thereof, ketones, esters, ethers, petroleum ethers. It is preferable to use an anhydrous or water-containing organic solvent containing at least one selected from aliphatic hydrocarbons or halides thereof and aromatic hydrocarbons, because the hair-growing effect is sufficiently exhibited.
Specifically, methanol, ethanol, isopropyl alcohol, n-propyl alcohol, isobutanol,
C1-C8 monohydric alcohols such as n-hexanol, methylamyl alcohol, 2-ethylbutanol, and n-octanol, ethylene glycol, propylene glycol, 1,3-butylene glycol, hexylene glycol, ethylene glycol monomethyl ether, Polyhydric alcohols having 2 to 6 carbon atoms such as ethylene glycol monoethyl ether, propylene glycol monomethyl ether, propylene glycol monoethyl ether or derivatives thereof, acetone, methylacetone, ethylmethylketone, isobutylmethylketone, methyl-n-propylketone Etc., C3-6 ketones, ethyl acetate, isopropyl acetate, etc. C4-5 esters, ethyl ether, isopropyl ether, n-butyl ether, etc. C4-8 acetones. Le and petroleum ether, n- butane, n
-Pentane, n-hexane, n-octane, etc. having 4 carbon atoms
Of aliphatic hydrocarbons having 1 to 8 carbon atoms, carbon tetrachloride, chloroform, dichloroethane, trichloroethylene and the like, halides of aliphatic hydrocarbons having 1 to 2 carbon atoms, and aromatic hydrocarbons having 6 to 7 carbon atoms such as benzene and toluene An anhydrous or water-containing organic solvent containing one or more of the above can be mentioned as a preferred example. Of course, liqueur or awamori may be used.

The extract obtained by distilling off the solvent from the extract obtained with the above-mentioned extraction solvent can be used as a hair-growth raw material, but when ethanol is used as the extraction solvent, ethanol is applied to the skin. Due to its high safety, the mixture can be used as a hair-growing agent raw material without distilling the solvent from the extract. The hair-growth agent raw material is used by diluting the extract obtained by alcohol extraction or boiling as described above with water containing a very small amount of divalent and trivalent iron salt. Examples of water derived from such an extremely small amount of divalent and trivalent iron salts include so-called π-water (registered trademark of IBB Co., Ltd.). It has been clarified that divalent and trivalent iron salts in π-water have a role of transmitting temperature and light information to plant seed genes, and the iron salt responsible for this gene information memory is
It has been ascertained that even ultra-small concentrations of 2 × 10 -12 moles will react. If this divalent and trivalent iron salt is neither too thick nor too thin, it will not become π water, so it is extremely difficult to generate π water by the water flow (running water) method. However, the water induced by such an ultra-trace amount of divalent and trivalent iron salts is neutral water with a pH of around 7, and also has a good balance of mineral components and high activity containing many enzymes. Therefore, it is considered that the activity thereof enhances the penetrating power of the above-mentioned hair-growth agent raw material into the scalp, and allows it to sufficiently exhibit the function originally possessed by the Thrush extract.

The hair restorer composition of the present invention contains one or more of the above hair restorer ingredients. The blending amount of the hair restorer raw material is not particularly limited, but if it is too small, the effect due to the blending of the hair restorer raw material will not be sufficiently exerted, so that it is 0.
The amount is preferably 01 to 100% by weight, and it is also possible to use only dry powder of plants, kukui nut oil, or extracts of plants as the hair restorer composition.

The hair-growth agent raw material according to the present invention includes, as hair-growth and hair-growth ingredients, for example, vitamin E and its derivatives, cembran extract, garlic extract, cepharanthin, carpronium chloride, acetylcholine, and other blood circulation promoters, capsicum tincture, and cans. Talis tincture, Ginger tincture,
Topical stimulants such as nonyl vanillamide, keratolytic agents such as salicylic acid, resorcin, lactic acid, placenta extract,
Metabolites such as pentadecanoic acid glyceride, pantothenyl ethyl ether, biotin, hinokitiol, allantoin, anti-inflammatory agents such as glycyrrhizinic acid and glycyrrhetinic acid, bactericides such as isopropylmethylphenol, triclosan, zinc pyrithione, hinokitiol, and cooling of menthol and camphor It is also possible to appropriately mix an agent and other female hormones.

Further, within a range that does not impair the effects of the present invention, alcohol, polyhydric alcohol, water-soluble polymer, antioxidant, pH adjuster, UV inhibitor, sequestering agent, thickener, interface. Ordinary cosmetic ingredients such as activators, fragrances, preservatives, antibacterial agents, oils, higher fatty acids, fatty acid esters, moisturizers, cooling agents, pigments, or hormones, vitamins, amino acids, astringents and placenta extracts, Elastin, collagen, mucopolysaccharide, aloe extract, loofah water,
Royal jelly, birch, carrot extract, chamomile extract, licorice extract, salvia extract, altea extract,
Special blending components such as animal and plant extract components including crude drug components such as yarrow extract and the like may be appropriately blended in accordance with the purpose.

The hair restorer composition according to the present invention can be used as a cosmetic, a quasi drug or a drug,
For example, it can be used as a hair tonic, a hair cream, and a hair treatment.

[0017]

[Test example; hair growth effect of extract]

(Example) Dried thrush (Elaeagnus glabra Thun)
b.) 500 g of 70% ethanol per 100 g of ground leaves
1 was added and the mixture was subjected to immersion extraction for 7 days. The extract was filtered and the solvent was distilled off to obtain 11.2 g of the extract. Groundwater drawn from the ground on the hillside in the suburbs of Himeji City, Hyogo Prefecture, was added to 1.5 g of this thrush extract to obtain ceramic filters, activated carbon made of coconut shells, strong magnets, and natural stones containing more minerals. Add a very small amount of water derived from divalent and trivalent iron salts obtained by passing each layer over several days to bring the total amount to 30
The sample solution of the example was obtained as ml.

Comparative Example A sample solution of Comparative Example was prepared by adding 99% ethanol to the above Thrush extract to make 30 ml.

[Test Method] C3H / HeN Crj mice (8 weeks old, weight 21-26 g) were acclimated and raised for 1 week or longer, and then those with no abnormalities had their back hair coated with electric clippers at 2 cm ×. Cut the hair to a size of 4 cm,
Furthermore, the hair was removed with an electric shaver and used as the administration site of the sample solution. Three days after the hair was removed, the sample solutions of Examples and Comparative Examples were applied to 10 mice each for 100 days in the morning, 100 μl each, for 19 consecutive days. During the test period, C3H /
HeN Crj mice have a temperature of 22 ± 2 ° C. and a relative humidity of 5
5 ± 15%, ventilation rate 20 times / hour, irradiation time set from 6:00 am to 6:00 pm, using a plastic cage (14.5 cm x 26 cm x 12.5 cm) in a breeding room 5
The animals were raised individually.

The condition of the sample application site was periodically observed, and scores were assigned according to the following evaluation criteria to calculate the average score of 10 animals. Skin is pink ... 0 points Skin changes to gray (less than 100%) 2 points Skin changes to gray (100%) 4 points Hair changes to brown (less than 100%) 6 points Hair growth Changes to brown (100%)… 8 points Hair changes to black… 10 points

The results are shown in Table 1.

[Table 1]

From the results shown in Table 1, the Turgus (Elaeagnus gl)
It can be seen that a solution obtained by diluting an extract of abra Thunb.) with water in which an extremely small amount of divalent and trivalent iron salts is diluted has an excellent hair-growing effect.

The following is a prescription example of a hair restorer composition containing the hair restorer raw material according to the present invention.

(Prescription example) Hair growth agent mix ratio (wt%) Obtained in the example Thrush extract 5.0 Tocopherol acetate 0.1 Pantothenyl alcohol 0.2 Dipotassium glycyrrhizinate 0.1 Quina extract 0.5 Polyoxyethylene (EO60) Hydrogenated castor oil 0.3 Perfume 0.1 Propylene glycol 2.0 The balance of mineral water Total 100.0

[0025]

As described in detail above, the present invention is applied to the trunks and leaves of Turdus (also known as Goupi Elaeagnus glabra Thunb.),
Alternatively, it is related to a hair-growth raw material obtained by extracting the fruit component by alcohol extraction or boiling and diluting it with water induced by an ultratrace amount of divalent and trivalent iron salts. Has the effect of having. Moreover, since it is derived from a natural product, it has an excellent effect that it is safe without causing an allergic reaction to the scalp.

Further, by diluting the extract of Thrush, with mineral water, it has the effect of having a high penetrating power to the scalp and being able to fully exhibit the function originally possessed by the extract.

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Claims (3)

[Claims] 1. A Turgusmi (also known as Goupi Elaeagnus glabra)
Thunb.) Stems, leaves, or fruit components obtained by alcohol extraction or boiling, and diluted with water inducing ultra trace amounts of ferric and trivalent iron salts. Raw material for hair-growth agents using turmeric. 2. A very small amount of water induced by a divalent and trivalent iron salt,
The hair restorer raw material according to claim 1, which is neutral water having a pH of around 7. 3. The alcohol extract is one or more selected from monohydric alcohols, polyhydric alcohols or derivatives thereof, ketones, esters, ethers, petroleum ethers, aliphatic hydrocarbons or halides thereof, and aromatic hydrocarbons. 2. A hair-growth agent raw material using the tsurushi according to claim 1, which is an extract containing an anhydrous or water-containing organic solvent.