JP2003081898A5 - - Google Patents
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- Publication number
- JP2003081898A5 JP2003081898A5 JP2002257373A JP2002257373A JP2003081898A5 JP 2003081898 A5 JP2003081898 A5 JP 2003081898A5 JP 2002257373 A JP2002257373 A JP 2002257373A JP 2002257373 A JP2002257373 A JP 2002257373A JP 2003081898 A5 JP2003081898 A5 JP 2003081898A5
- Authority
- JP
- Japan
- Prior art keywords
- group
- ene
- alkylene
- heteroatoms
- alkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 229910052757 nitrogen Inorganic materials 0.000 claims 19
- 125000005842 heteroatom Chemical group 0.000 claims 15
- 229910052760 oxygen Inorganic materials 0.000 claims 14
- 238000000034 method Methods 0.000 claims 10
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 claims 8
- 239000002585 base Substances 0.000 claims 7
- 229910052799 carbon Inorganic materials 0.000 claims 7
- 125000004432 carbon atom Chemical group C* 0.000 claims 7
- 229920006395 saturated elastomer Polymers 0.000 claims 6
- -1 C 1 -C 4 alkoxy Chemical group 0.000 claims 5
- 125000003118 aryl group Chemical group 0.000 claims 5
- RTZKZFJDLAIYFH-UHFFFAOYSA-N ether Substances CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 claims 4
- 229910052739 hydrogen Inorganic materials 0.000 claims 4
- BASFCYQUMIYNBI-UHFFFAOYSA-N platinum Chemical compound [Pt] BASFCYQUMIYNBI-UHFFFAOYSA-N 0.000 claims 4
- 150000001721 carbon Chemical group 0.000 claims 3
- 239000003054 catalyst Substances 0.000 claims 3
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 claims 3
- 125000003161 (C1-C6) alkylene group Chemical group 0.000 claims 2
- 125000006656 (C2-C4) alkenyl group Chemical group 0.000 claims 2
- 125000006552 (C3-C8) cycloalkyl group Chemical group 0.000 claims 2
- VHUUQVKOLVNVRT-UHFFFAOYSA-N Ammonium hydroxide Chemical group [NH4+].[OH-] VHUUQVKOLVNVRT-UHFFFAOYSA-N 0.000 claims 2
- 125000002853 C1-C4 hydroxyalkyl group Chemical group 0.000 claims 2
- 125000004406 C3-C8 cycloalkylene group Chemical group 0.000 claims 2
- 125000000217 alkyl group Chemical group 0.000 claims 2
- 125000002947 alkylene group Chemical group 0.000 claims 2
- 125000000113 cyclohexyl group Chemical group [H]C1([H])C([H])([H])C([H])([H])C([H])(*)C([H])([H])C1([H])[H] 0.000 claims 2
- 125000000592 heterocycloalkyl group Chemical group 0.000 claims 2
- 125000006588 heterocycloalkylene group Chemical group 0.000 claims 2
- 229910052697 platinum Inorganic materials 0.000 claims 2
- 125000004767 (C1-C4) haloalkoxy group Chemical group 0.000 claims 1
- 125000004765 (C1-C4) haloalkyl group Chemical group 0.000 claims 1
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical group [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 claims 1
- 235000021513 Cinchona Nutrition 0.000 claims 1
- 241000157855 Cinchona Species 0.000 claims 1
- 125000002723 alicyclic group Chemical group 0.000 claims 1
- 125000001931 aliphatic group Chemical group 0.000 claims 1
- 150000008044 alkali metal hydroxides Chemical class 0.000 claims 1
- 229930013930 alkaloid Natural products 0.000 claims 1
- 150000003797 alkaloid derivatives Chemical class 0.000 claims 1
- 125000004848 alkoxyethyl group Chemical group 0.000 claims 1
- 125000001118 alkylidene group Chemical group 0.000 claims 1
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 claims 1
- 125000000649 benzylidene group Chemical group [H]C(=[*])C1=C([H])C([H])=C([H])C([H])=C1[H] 0.000 claims 1
- 150000001875 compounds Chemical class 0.000 claims 1
- 229920001577 copolymer Polymers 0.000 claims 1
- 150000001923 cyclic compounds Chemical class 0.000 claims 1
- 125000004210 cyclohexylmethyl group Chemical group [H]C([H])(*)C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H] 0.000 claims 1
- 229910052736 halogen Inorganic materials 0.000 claims 1
- 150000002367 halogens Chemical class 0.000 claims 1
- 150000002390 heteroarenes Chemical class 0.000 claims 1
- 125000001072 heteroaryl group Chemical group 0.000 claims 1
- 238000005984 hydrogenation reaction Methods 0.000 claims 1
- 125000001624 naphthyl group Chemical group 0.000 claims 1
- 125000004433 nitrogen atom Chemical group N* 0.000 claims 1
- 125000000109 phenylethoxy group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])O* 0.000 claims 1
- 125000000286 phenylethyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])* 0.000 claims 1
- 239000011541 reaction mixture Substances 0.000 claims 1
- 239000007787 solid Substances 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH20011648/01 | 2001-09-05 | ||
| CH16482001 | 2001-09-05 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2003081898A JP2003081898A (ja) | 2003-03-19 |
| JP2003081898A5 true JP2003081898A5 (enExample) | 2005-11-04 |
Family
ID=4565756
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2002257373A Pending JP2003081898A (ja) | 2001-09-05 | 2002-09-03 | 光学活性を有するα−ヒドロキシエーテルの製造 |
Country Status (3)
| Country | Link |
|---|---|
| US (1) | US6617475B2 (enExample) |
| EP (1) | EP1291336A3 (enExample) |
| JP (1) | JP2003081898A (enExample) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7705036B2 (en) * | 2004-04-01 | 2010-04-27 | Cardiome Pharma Corp. | Deuterated aminocyclohexyl ether compounds and processes for preparing same |
| JP5159314B2 (ja) | 2004-11-18 | 2013-03-06 | カーディオム ファーマ コーポレイション | アミノシクロヘキシルエーテル化合物の合成方法 |
| BRPI0612138B8 (pt) | 2005-06-15 | 2021-05-25 | Cardiome Pharma Corp | compostos éter aminocicloexílicos e método para fazer os mesmos |
| DE102010046720A1 (de) | 2010-09-23 | 2012-03-29 | Bayer Schering Pharma Aktiengesellschaft | Verfahren zur Herstellung von pan-CDK-Inhibitoren der Formel (l), sowie Intermediate der Herstellung |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3818013A (en) * | 1970-04-09 | 1974-06-18 | American Home Prod | 2-substituted-cinchona alkaloids |
| JPS5823861B2 (ja) * | 1979-06-05 | 1983-05-18 | 工業技術院長 | α−ケトエステルの不斉水素化方法 |
| US4785089A (en) * | 1985-06-13 | 1988-11-15 | Ciba-Geigy Corporation | Novel sulfonic acid esters and their preparation |
| JPH0730062B2 (ja) * | 1986-01-06 | 1995-04-05 | 日産化学工業株式会社 | ケトパントラクトンの不斉水素化法 |
| TR200002822T2 (tr) * | 1998-03-31 | 2001-01-22 | Ciba Specialty Chemicals Holding Inc. | HPB esterlerinin hazırlanması için bir işlem. |
| AU1379200A (en) * | 1999-06-23 | 2001-01-31 | Solvias Ag | Production of optically active alpha-hydroxyacetals |
-
2002
- 2002-08-07 EP EP02017575A patent/EP1291336A3/en not_active Withdrawn
- 2002-09-03 JP JP2002257373A patent/JP2003081898A/ja active Pending
- 2002-09-04 US US10/233,441 patent/US6617475B2/en not_active Expired - Fee Related
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