JP2003064046A5 - - Google Patents
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- Publication number
- JP2003064046A5 JP2003064046A5 JP2002161471A JP2002161471A JP2003064046A5 JP 2003064046 A5 JP2003064046 A5 JP 2003064046A5 JP 2002161471 A JP2002161471 A JP 2002161471A JP 2002161471 A JP2002161471 A JP 2002161471A JP 2003064046 A5 JP2003064046 A5 JP 2003064046A5
- Authority
- JP
- Japan
- Prior art keywords
- compound
- group
- formula
- tosyl
- mesyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 150000001875 compounds Chemical class 0.000 description 28
- 125000006239 protecting group Chemical group 0.000 description 8
- 125000002088 tosyl group Chemical group [H]C1=C([H])C(=C([H])C([H])=C1C([H])([H])[H])S(*)(=O)=O 0.000 description 8
- 125000004170 methylsulfonyl group Chemical group [H]C([H])([H])S(*)(=O)=O 0.000 description 6
- 125000003865 brosyl group Chemical group [H]C1=C([H])C(=C([H])C([H])=C1Br)S(*)(=O)=O 0.000 description 5
- 125000001736 nosyl group Chemical group S(=O)(=O)(C1=CC=C([N+](=O)[O-])C=C1)* 0.000 description 5
- 125000002947 alkylene group Chemical group 0.000 description 4
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 description 3
- 239000000203 mixture Substances 0.000 description 3
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 description 3
- 150000003839 salts Chemical class 0.000 description 3
- 125000000472 sulfonyl group Chemical group *S(*)(=O)=O 0.000 description 3
- 230000002194 synthesizing effect Effects 0.000 description 3
- 125000000843 phenylene group Chemical group C1(=C(C=CC=C1)*)* 0.000 description 2
- NHTGHBARYWONDQ-JTQLQIEISA-N L-α-methyl-Tyrosine Chemical compound OC(=O)[C@](N)(C)CC1=CC=C(O)C=C1 NHTGHBARYWONDQ-JTQLQIEISA-N 0.000 description 1
- AXDLCFOOGCNDST-UHFFFAOYSA-N N-methyl-DL-tyrosine Natural products CNC(C(O)=O)CC1=CC=C(O)C=C1 AXDLCFOOGCNDST-UHFFFAOYSA-N 0.000 description 1
- 125000000217 alkyl group Chemical group 0.000 description 1
- 125000005816 fluoropropyl group Chemical group [H]C([H])(F)C([H])([H])C([H])([H])* 0.000 description 1
- 229910052736 halogen Inorganic materials 0.000 description 1
- 150000002367 halogens Chemical class 0.000 description 1
- 239000000543 intermediate Substances 0.000 description 1
- 239000002904 solvent Substances 0.000 description 1
- -1 trifil Chemical group 0.000 description 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/872,156 US6824760B2 (en) | 2001-06-04 | 2001-06-04 | Imaging agents, precursors thereof and methods of manufacture |
| US09/872156 | 2001-06-04 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2003064046A JP2003064046A (ja) | 2003-03-05 |
| JP2003064046A5 true JP2003064046A5 (enExample) | 2008-02-14 |
Family
ID=25358962
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2002161471A Pending JP2003064046A (ja) | 2001-06-04 | 2002-06-03 | 新造影剤、その前駆体、及び、製造方法 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US6824760B2 (enExample) |
| JP (1) | JP2003064046A (enExample) |
| KR (1) | KR100483650B1 (enExample) |
| CN (1) | CN1234680C (enExample) |
| TW (1) | TWI244925B (enExample) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20060115426A1 (en) * | 2004-08-11 | 2006-06-01 | Weichert Jamey P | Methods of detecting breast cancer, brain cancer, and pancreatic cancer |
| US8845999B2 (en) * | 2005-05-23 | 2014-09-30 | The Regents Of The University Of California | Tracers for monitoring the activity of sodium/glucose cotransporters in health and disease |
| EP2046686A1 (en) * | 2006-08-03 | 2009-04-15 | Hammersmith Imanet, Ltd | Fluoride drying method |
| WO2012025464A1 (en) | 2010-08-24 | 2012-03-01 | Bayer Pharma Aktiengesellschaft | Fluorodeuteriomethyl tyrosine derivatives |
| GB201021530D0 (en) * | 2010-12-20 | 2011-02-02 | Ge Healthcare Ltd | Purification of precursor compound by crystallisation |
| EP2520557A1 (en) * | 2011-05-03 | 2012-11-07 | Bayer Pharma Aktiengesellschaft | Novel precursors of glutamate derivatives |
| WO2015152128A1 (ja) * | 2014-03-31 | 2015-10-08 | 長瀬産業株式会社 | アミノ酸前駆体、アミノ酸およびその製造方法、ならびに該アミノ酸を用いたｐｅｔ診断用トレーサー |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3800302A1 (de) * | 1988-01-08 | 1989-07-27 | Kernforschungsanlage Juelich | Radiohalogentyrosinderivate, deren herstellung und verwendung |
-
2001
- 2001-06-04 US US09/872,156 patent/US6824760B2/en not_active Expired - Fee Related
-
2002
- 2002-06-03 JP JP2002161471A patent/JP2003064046A/ja active Pending
- 2002-06-04 TW TW091111997A patent/TWI244925B/zh not_active IP Right Cessation
- 2002-06-04 KR KR10-2002-0031228A patent/KR100483650B1/ko not_active Expired - Fee Related
- 2002-06-04 CN CNB02122255XA patent/CN1234680C/zh not_active Expired - Fee Related
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